Niels Mailand
Professor, head of research, Professor
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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75Research output: Contribution to journal › Journal article › Research › peer-review
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TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
Falck, J., Mailand, Niels, Syljuåsen, R. G., Bartek, J. & Lukas, Jiri, 12 Apr 2001, In: Nature. 410, 6830, p. 842-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure
Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313Research output: Contribution to journal › Journal article › Research › peer-review
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The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
Singh, A. N., Oehler, J., Torrecilla, I., Kilgas, S., Li, S., Vaz, B., Guerillon, C., Fielden, J., Esperanza Hernandez-Carralero, Cabrera, E., Tullis, I. D. C., Meerang, M., Barber, P. R., Freire, R., Parsons, J., Vojnovic, B., Kiltie, A. E., Mailand, Niels & Ramadan, K., 2019, In: EMBO Journal. 38, 25 p.Research output: Contribution to journal › Journal article › Research › peer-review
The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen
Gérard, A., Koundrioukoff, S., Ramillon, V., Sergère, J., Mailand, Niels, Quivy, J. & Almouzni, G., 2006, In: E M B O Reports. 7, 8, p. 817-23 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks
Bekker-Jensen, Simon Holst & Mailand, Niels, 12 Jun 2011, In: FEBS Letters. 585, p. 2914-2919 6 p.Research output: Contribution to journal › Review › Research › peer-review
ID: 13844358
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2010
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Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
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1721
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Molecular basis and regulation of OTULIN-LUBAC interaction
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
902
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Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Research output: Contribution to journal › Letter › Research › peer-review
Published