Jakob Nilsson

Jakob Nilsson

professor, group leader

Jakob Nilsson is Associate Professor at Novo Nordisk Foundation Center for Protein Research, which he joined in 2011. Jakob did his PhD studies in the lab of Professor Jørgen Kjems, University of Aarhus, working on the small GTPase Ran. Following this, he joined Professor Poul Nissens Group, University of Aarhus, and studied structural aspects of the eukaryotic ribosome using cryo-EM. In 2005, he initiated his second Postdoc in the lab of Jonathon Pines at the Gurdon Institute, University of Cambridge, where he focused on understanding how cells accurately segregate their chromosomes during mitosis. In 2009, he was awarded the Lundbeck Foundation Junior Group Leader Fellowship to establish his own lab at BRIC, University of Copenhagen, focusing on mitotic regulation. In 2011, he moved to Novo Nordisk Foundation Center for Protein Research where he has continued his work on cell division.

Selected publications

  1. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Yumi, Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, M. S. Y., Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In : Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

    Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, Fabian, Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In : E M B O Journal. 38, 7, e100977.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

    Kruse, Thomas, Biedenkopf, N., Hertz, Emil Peter Thrane, Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, Jakob & Becker, S., 4 Jan 2018, In : Molecular Cell. 69, 1, p. 136-145 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

    Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In : Nature Communications. 8, 12 p., 15822.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

    bmk286, bmk286, Hertz, Emil Peter Thrane, Garvanska, Dimitriya Hristoforova, Kruse, Thomas & Nilsson, Jakob, 2017, In : Nature Cell Biology. 19, p. 1433-1440

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

    Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In : Molecular Cell. 63, 4, p. 686-695 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

    Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In : Nature Communications. 7, p. 1-12 12 p., 12256.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8799501