Niels Mailand

Niels Mailand

Professor, head of research, Professor

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    ORCID: 0000-0002-6623-709X

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    1. Published

      RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

      Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

      Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In: Genes & Development. 27, 22, p. 2459-2472 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Human Cdc14A phosphatase modulates the G2/M transition through Cdc25A and Cdc25B

      Vázquez-Novelle, M. D., Mailand, Niels, Ovejero, S., Bueno, A. & Sacristán, M. P., 2010, In: Journal of Biological Chemistry. 285, 52, p. 40544-53 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

      Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

      Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair

      Van Cuijk, L., Van Belle, G. J., Turkyilmaz, Y., Poulsen, S. L., Janssens, R. C., Theil, A. F., Sabatella, M., Lans, H., Mailand, Niels, Houtsmuller, A. B., Vermeulen, W. & Marteijn, J. A., 7 Jul 2015, In: Nature Communications. 6, 10 p., 7499.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      An unorthodox partnership in DNA repair pathway choice

      Typas, D. & Mailand, Niels, 2019, In: EMBO Reports. 20, 11, e49105.

      Research output: Contribution to journal › Editorial › Research › peer-review

    8. Published

      GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling

      Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

      Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Centriolar satellites: key mediators of centrosome functions

      Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    11. Published

      ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

      Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

      Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    13. Published

      TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

      Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair

      Smeenk, G. & Mailand, Niels, 28 Jun 2016, In: Frontiers in Genetics. 7, 14 p., 122.

      Research output: Contribution to journal › Review › Research › peer-review

    15. Published

      Poly(ADP-ribosyl)ation links the chromatin remodeler SMARCA5/SNF2H to RNF168-dependent DNA damage signaling

      Smeenk, G., Wiegant, W. W., Luijsterburg, M. S., Costelloe, T., Romeijn, R. J., Pastink, A., van Attikum, H., Marteijn, J. A., Vermeulen, W., Sroczynski, N. & Mailand, Niels, 15 Feb 2013, In: Journal of Cell Science. 126, 4, p. 889-903 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      The p97-Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8

      Singh, A. N., Oehler, J., Torrecilla, I., Kilgas, S., Li, S., Vaz, B., Guerillon, C., Fielden, J., Esperanza Hernandez-Carralero, Cabrera, E., Tullis, I. D. C., Meerang, M., Barber, P. R., Freire, R., Parsons, J., Vojnovic, B., Kiltie, A. E., Mailand, Niels & Ramadan, K., 2019, In: EMBO Journal. 38, 25 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      K27-linked ubiquitylation promotes p97 substrate processing and is essential for cell proliferation

      Shearer, Robert Francis, Typas, D., Coscia, F., Schovsbo, Sofie Ulfbeck, Kruse, Thomas, Mund, Andreas & Mailand, Niels, 2022, In: E M B O Journal. 41, 9, 18 p., e110145.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

      Schwertman, P., Bekker-Jensen, Simon Holst & Mailand, Niels, Jun 2016, In: Nature Reviews. Molecular Cell Biology. 17, 6, p. 379-94 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      RADX interacts with single-stranded DNA to promote replication fork stability

      Schubert, Lisa, Ho, T., Hoffmann, Saskia, Haahr, Peter Thorlund, Guérillon, C. & Mailand, Niels, Nov 2017, In: EMBO Reports. 18, 11, p. 1991-2003 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

      Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

      Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway

      Santoni Rugiu, Eric, Falck, J., Mailand, Niels, Bartek, J. & Lukas, Jiri, May 2000, In: Molecular and Cellular Biology. 20, 10, p. 3497-509 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

      Räschle, M., Smeenk, G., Hansen, R. K., Temu, T., Oka, Y., Hein, M. Y., Nagaraj, N., Long, D. T., Walter, J. C., Hofmann, K., Storchova, Z., Cox, J., Bekker-Jensen, Simon Holst, Mailand, Niels & Mann, Matthias, 2015, In: Science. 348, 6234, p. 539- 10 p., 1253671.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation

      Rabl, J., Bunker, R. D., Schenk, A. D., Cavadini, S., Gill, M. E., Abdulrahman, W., Andrés-Pons, A., Luijsterburg, M. S., Ibrahim, A. F. M., Branigan, E., Aguirre, J. D., Marceau, A. H., Guérillon, C., Bouwmeester, T., Hassiepen, U., Peters, A. H. F. M., Renatus, M., Gelman, L., Rubin, S. M., Mailand, N. & 3 others, van Attikum, H., Hay, R. T. & Thomä, N. H., 2019, In: Molecular Cell. 75, 3, p. 483-497.e9 25 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

      Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 13844358