Lars Juhl Jensen

Lars Juhl Jensen

Professor, Group Leader, Professor

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    ORCID: 0000-0001-7885-715X

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    1. Published

      Acetylation site specificities of lysine deacetylase inhibitors in human cells

      Schölz, C., Weinert, B. T., Wagner, S. A., Beli, P., Miyake, Y., Qi, J., Jensen, Lars Juhl, Streicher, W., McCarthy, A. R., Westwood, N. J., Lain, S., Cox, J., Matthias, P., Mann, M., Bradner, J. E. & Choudhary, Chunaram, 2015, In: Nature Biotechnology. 33, p. 415–423

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Microblogging the ISMB: a new approach to conference reporting

      Saunders, N., Beltrão, P., Jurczak, D., Krause, R., Kuhn, M., Wu, S. & Jensen, Lars Juhl, 2009, In: PLoS Computational Biology. 5, 1, p. e1000263

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Large-scale extraction of gene regulation for model organisms in an ontological context

      Saric, J., Jensen, Lars Juhl & Rojas, I., 2005, In: In Silico Biology. 5, 1, p. 21-32 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Extraction of regulatory gene/protein networks from Medline

      Saric, J., Jensen, Lars Juhl, Ouzounova, R., Rojas, I. & Bork, P., 2006, In: Bioinformatics. 22, 6, p. 645-50 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Cyclebase 3.0: a multi-organism database on cell-cycle regulation and phenotypes

      Santos Delgado, A., Wernersson, R. & Jensen, Lars Juhl, Jan 2015, In: Nucleic Acids Research. 43, D1, p. D1140-4 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Comprehensive comparison of large-scale tissue expression datasets

      Santos Delgado, A., Tsafou, K., Stolte, C., Pletscher-Frankild, S., O'Donoghue, S. I. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, e1054.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      A knowledge graph to interpret clinical proteomics data

      Santos, A., Colaço, A. R., Nielsen, A. B., Niu, Lili, Strauss, Maximilian, Geyer, P. E., Coscia, F., Albrechtsen, Nicolai Jacob Wewer, Mundt, F., Jensen, Lars Juhl & Mann, Matthias, 2022, In: Nature Biotechnology. 40, p. 692–702

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      miRandola 2017: a curated knowledge base of non-invasive biomarkers

      Russo, F., Di Bella, S., Vannini, F., Berti, G., Scoyni, F., Cook, H. V., Santos, A., Nigita, G., Bonnici, V., Laganà, A., Geraci, F., Pulvirenti, A., Giugno, R., De Masi, F., Belling, K., Jensen, Lars Juhl, Brunak, Søren, Pellegrini, M. & Ferro, A., 1 Jan 2018, In: Nucleic Acids Research. 46, D1, p. D354-D359 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      A comparison of protein kinases inhibitor screening methods using both enzymatic activity and binding affinity determination

      Rudolf, A. F., Skovgaard, T., Knapp, S., Jensen, Lars Juhl & Berthelsen, J., 2014, In: PloS one. 9, 6, p. 1-5 6 p., e98800.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Using electronic patient records to discover disease correlations and stratify patient cohorts

      Roque, F. S., Jensen, P. B., Schmock, H., Dalgaard, M., Andreatta, M., Hansen, T., Søeby, K., Bredkjær, S., Juul, Anders, Werge, Thomas, Jensen, Lars Juhl & Brunak, Søren, 2011, In: P L o S Computational Biology. 7, 8, p. e1002141 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Transcriptional regulation is a major controller of cell cycle transition dynamics

      Romanel, A., Jensen, Lars Juhl, Cardelli, L. & Csikász-Nagy, A., 2012, In: P L o S One. 7, 1, p. e29716

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Hunting for the elusive target antigen in gestational alloimmune liver disease (GALD)

      Rieneck, K., Rasmussen, K. K., Schoof, E. M., Clausen, F. B., Holze, H., Bergholt, Thomas, Jørgensen, M. H., Christensen, Vibeke Brix, Almaas, R., Jordal, P. L., Locard-Paulet, Marie, Runager, K., Nielsen, L. K., Schlotmann, Balthasar Clemens, Weischenfeldt, Joachim Lütken, Jensen, Lars Juhl & Dziegiel, Morten Hanefeld, 2023, In: PLoS ONE. 18, 10, 25 p., e0286432.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Search Databases and Statistics: Pitfalls and Best Practices in Phosphoproteomics

      Refsgaard, J. C., Munk, S. & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer Publishing Company, Vol. 1355. p. 323-39 17 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    14. E-pub ahead of print

      A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

      Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Toward molecular trait-based ecology through integration of biogeochemical, geographical and metagenomic data

      Raes, J., Letunic, I., Yamada, T., Jensen, Lars Juhl & Bork, P., 2011, In: Molecular Systems Biology. 7, p. 473

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      eggNOG v4.0: nested orthology inference across 3686 organisms

      Powell, S., Forslund, K., Szklarczyk, D. M., Trachana, K., Roth, A., Huerta-Cepas, J., Gabaldón, T., Rattei, T., Creevey, C., Kuhn, M., Jensen, Lars Juhl, von Mering, C. & Bork, P., 1 Dec 2013, In: Nucleic Acids Research. 42, D1, p. D231-D239 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      eggNOG v3.0: Orthologous groups covering 1133 organisms at 41 different taxonomic ranges

      Powell, S., Trachana, K., Letunic, I., Doerks, T., Bork, P., Szklarczyk, D., Jensen, Lars Juhl, Roth, A., Von Mering, C., Kuhn, M., Muller, J., Arnold, R. & Rattei, T., 2012, In: Nucleic Acids Research. 40, D1, p. D284-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

      Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In: Journal of Proteomics. 75, 13, p. 3886-97 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Design, implementation, and operation of a rapid, robust named entity recognition web service

      Pletscher-Frankild, S. & Jensen, Lars Juhl, 2019, In: Journal of Cheminformatics. 11, 6 p., 19.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      DISEASES: Text mining and data integration of disease-gene associations

      Pletscher-Frankild, S., Pallejà, A., Tsafou, K., Binder, J. X. & Jensen, Lars Juhl, Mar 2015, In: Methods. 74, p. 83-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

      Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Assessing systems properties of yeast mitochondria through an interaction map of the organelle

      Perocchi, F., Jensen, Lars Juhl, Gagneur, J., Ahting, U., von Mering, C., Bork, P., Prokisch, H. & Steinmetz, L. M., 2006, In: P L o S Genetics (Online). 2, 10, p. e170

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Impact of microRNA-130a on the neutrophil proteome

      Pedersen, C. C., Refsgaard, J. C., Østergaard, Ole, Jensen, Lars Juhl, Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. A DNA structural atlas for Escherichia coli

      Pedersen, A. G., Jensen, Lars Juhl, Brunak, S., Staerfeldt, H. H. & Ussery, D., 2000, In: Journal of Molecular Biology. 299, 4, p. 907-30 24 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      BioStar: an online question & answer resource for the bioinformatics community

      Parnell, L. D., Lindenbaum, P., Shameer, K., Dall'Olio, G. M., Swan, D. C., Jensen, Lars Juhl, Cockell, S. J., Pedersen, B. S., Mangan, M. E., Miller, C. A. & Albert, I., 2011, In: P L o S Computational Biology (Online). 7, 10, p. e1002216

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Genome-wide identification of clusters of predicted microRNA binding sites as microRNA sponge candidates

      Pan, X., Wenzel, Anne, Jensen, Lars Juhl & Gorodkin, Jan, 2018, In: PLoS ONE. 13, 8, 15 p., e0202369.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      Inferring disease-associated long non-coding RNAs using genome - wide tissue expression profiles

      Pan, X., Jensen, Lars Juhl & Gorodkin, Jan, 2019, In: Bioinformatics. 35, 9, p. 1494-1502 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      WebCircRNA: Classifying the Circular RNA Potential of Coding and Noncoding RNA.

      Pan, X., Xiong, K., Anthon, Christian, Hyttel, P., Freude, Kristine, Jensen, Lars Juhl & Gorodkin, Jan, 6 Nov 2018, In: Genes. 9, 11, 11 p., 536.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      DistiLD Database: diseases and traits in linkage disequilibrium blocks

      Palleja, A., Horn, H., Eliasson, S. & Jensen, Lars Juhl, 2012, In: Nucleic Acids Research. 40, Database issue, p. D1036-40

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      HOODS: finding context-specific neighborhoods of proteins, chemicals and diseases

      Palleja, A. & Jensen, Lars Juhl, 2015, In: PeerJ. 3, p. 1-10 10 p., e1057.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      TISSUES 2.0: an integrative web resource on mammalian tissue expression

      Palasca, Oana, Santos, A., Stolte, C., Gorodkin, Jan & Jensen, Lars Juhl, 2018, In: Database: The Journal of Biological Databases and Curation. 2018, 1, p. 1-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      EXTRACT: interactive extraction of environment metadata and term suggestion for metagenomic sample annotation

      Pafilis, E., Buttigieg, P. L., Ferrell, B., Pereira, E., Schnetzer, J., Arvanitidis, C. & Jensen, Lars Juhl, 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 7 p., baw005.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      The SPECIES and ORGANISMS Resources for Fast and Accurate Identification of Taxonomic Names in Text

      Pafilis, E., Pletscher-Frankild, S., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, A., Arvanitidis, C. & Jensen, Lars Juhl, 18 Jun 2013, In: PloS one. 8, 6, p. e65390

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Reflect: augmented browsing for the life scientist

      Pafilis, E., O'Donoghue, S. I., Jensen, Lars Juhl, Horn, H., Kuhn, M., Brown, N. P. & Schneider, R., 2009, In: Nature Biotechnology. 27, 6, p. 508-10 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      ENVIRONMENTS and EOL: identification of Environment Ontology terms in text and the annotation of the Encyclopedia of Life

      Pafilis, E., Pletscher-Frankild, S., Schnetzer, J., Fanini, L., Faulwetter, S., Pavloudi, C., Vasileiadou, K., Leary, P., Hammock, J., Schulz, K., Parr, C. S., Arvanitidis, C. & Jensen, Lars Juhl, 2015, In: Bioinformatics. 31, 11, p. 1872-1874

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse

      Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, Dolocan, A., Stenderup, Jesper Tandberg, Velazquez, A. M. V., Cahill, J., Rasmussen, M., Wang, X., Min, J., Zazula, G. D., Seguin-Orlando, A., Mortensen, C., Magnussen, K., Thompson, J. F., Weinstock, J., Gregersen, K., Røed, K. H., Eisenmann, V., Rubin, C. J., Miller, D. C., Antczak, D. F., Bertelsen, M. F., Brunak, S., Al-Rasheid, K. A. S., Ryder, O., Andersson, L., Mundy, J., Krogh, Anders, Gilbert, M Thomas P, Kjær, Kurt H., Sicheritz-Pontén, T., Jensen, Lars Juhl, Olsen, Jesper Velgaard, Hofreiter, M., Nielsen, R., Shapiro, B., Wang, J. & Willerslev, Eske, 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    37. Published

      Overview of the Knowledge Management Center for Illuminating the Druggable Genome

      Oprea, T. I., Bologa, C., Holmes, J., Mathias, S., Metzger, V. T., Waller, A., Yang, J. J., Leach, A. R., Jensen, Lars Juhl, Kelleher, K. J., Sheils, T. K., Mathé, E., Avram, S. & Edwards, J. S., 2024, In: Drug Discovery Today. 29, 3, 8 p., 103882.

      Research output: Contribution to journal › Review › Research › peer-review

    38. Published

      Unexplored therapeutic opportunities in the human genome

      Oprea, T. I., Bologa, C. G., Brunak, S., Campbell, A., Gan, G. N., Gaulton, A., Gomez, S. M., Guha, R., Hersey, A., Holmes, J., Jadhav, A., Jensen, L. J., Johnson, G. L., Karlson, A., Leach, A. R., Ma'ayan, A., Malovannaya, A., Mani, S., Mathias, S. L., McManus, M. T. & 21 others, Meehan, T. F., von Mering, C., Muthas, D., Nguyen, D., Overington, J. P., Papadatos, G., Qin, J., Reich, C., Roth, B. L., Schürer, S. C., Simeonov, A., Sklar, L. A., Southall, N., Tomita, S., Tudose, I., Ursu, O., Vidovic, D., Waller, A., Westergaard, David, Yang, J. J. & Zahoránszky-Köhalmi, G., 2018, In: Nature Reviews. Drug Discovery. 17, 5, p. 317-332 16 p.

      Research output: Contribution to journal › Review › Research › peer-review

    39. Published

      Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

      Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Reflect: a practical approach to web semantics

      O'Donoghue, S. I., Horn, H., Pafilisa, E., Haag, S., Kuhn, M., Satagopam, V. P., Schneider, R. & Jensen, Lars Juhl, Jul 2010, In: Journal of Web Semantics. 8, 2-3, p. 182-189

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      Improved metagenome binning and assembly using deep variational autoencoders

      Nissen, J. N., Johansen, Joachim, Allesoe, R. L., Sonderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Jensen, Lars Juhl, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2021, In: Nature Biotechnology. 39, p. 555-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      Pharos: Collating protein information to shed light on the druggable genome

      Nguyen, D-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schürer, S., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 2017, In: Nucleic Acids Research. 45, D1, p. D995–D1002

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Protein-driven inference of miRNA-disease associations

      Mørk, S., Pletscher-Frankild, S., Palleja, A., Gorodkin, Jan & Jensen, Lars Juhl, 2014, In: Bioinformatics (Oxford, England). 30, 3, p. 392-397 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      From Phosphosites to Kinases

      Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    45. Published

      eggNOG v2.0: extending the evolutionary genealogy of genes with enhanced non-supervised orthologous groups, species and functional annotations

      Muller, J., Szklarczyk, D., Julien, P., Letunic, I., Roth, A., Kuhn, M., Powell, S., von Mering, C., Doerks, T., Jensen, Lars Juhl & Bork, P., 1 Jan 2010, In: Nucleic Acids Symposium Series. 38, Database issue, p. D190-5

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification

      Mullari, M., Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In: Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Linear motif atlas for phosphorylation-dependent signaling

      Miller, M. L., Jensen, L. J., Diella, F., Jørgensen, C., Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E. & 3 others, Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In: Science Signaling. 1, 35, p. ra2

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. The more the merrier: comparative analysis of microarray studies on cell cycle-regulated genes in fission yeast

      Marguerat, S., Jensen, T. S., de Lichtenberg, U., Wilhelm, B. T., Jensen, Lars Juhl & Bähler, J., 2006, In: Yeast (Chichester, England). 23, 4, p. 261-77 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting

      Mackie, Meaghan, Rüther, P. L., Samodova, D., Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In: Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Structure-based discovery of novel US28 small molecule ligands with different modes of action

      Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296

      Research output: Contribution to journal › Journal article › Research › peer-review

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