Jesper Velgaard Olsen

Jesper Velgaard Olsen

Professor, Deputy Head of Centre, Professor

Member of:


    1. Published

      Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)

      Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    2. Published

      Limits for resolving isobaric tandem mass tag reporter ions using phase constrained spectrum deconvolution

      Kelstrup, C. D., Aizikov, K., Batth, Tanveer Singh, Kreutzman, A., Grinfeld, D., Lange, O., Mourad, D., Makarov, A. A. & Olsen, Jesper Velgaard, 2 Nov 2018, In: Journal of Proteome Research. 17, 11, p. 4008-4016 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures

      Kjær, I., Lindsted, T., Fröhlich, C., Olsen, Jesper Velgaard, Horak, I. D., Kragh, M. & Pedersen, M. W., Jul 2016, In: Molecular Cancer Therapeutics. 15, 7, p. 1614-1626 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. The low molecular weight proteome of Halobacterium salinarum

      Klein, C., Aivaliotis, M., Olsen, Jesper Velgaard, Falb, M., Besir, H., Scheffer, B., Bisle, B., Tebbe, A., Konstantinidis, K., Siedler, F., Pfeiffer, F., Mann, Matthias & Oesterhelt, D., 2007, In: Journal of Proteome Research. 6, 4, p. 1510-8 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Ubc9 sumoylation regulates SUMO target discrimination

      Knipscheer, P., Flotho, A., Klug, H., Olsen, Jesper Velgaard, van Dijk, W. J., Fish, A., Johnson, E. S., Mann, M., Sixma, T. K. & Pichler, A., 2008, In: Molecular Cell. 31, 3, p. 371-82 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

      Knipscheer, P., van Dijk, W. J., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: EMBO Journal. 26, 11, p. 2797-807 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    7. Published

      Protocol for high-throughput semi-automated label-free- or TMT-based phosphoproteome profiling

      Koenig, Claire, Martinez Del Val, Ana, Naicker, P., Stoychev, S., Jordaan, J. & Olsen, Jesper Velgaard, 2023, In: STAR Protocols. 4, 3, 30 p., 102536.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Optimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing

      Koenig, Claire, Martinez-Val, A., Franciosa, Giulia & Olsen, Jesper Velgaard, 2022, In: Proteomics. 22, 19-20, 13 p., 2100245.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

      Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published
    11. Published

      Multi-protease analysis of Pleistocene bone proteomes

      Lanigan, Liam Thomas, Mackie, Meaghan, Feine, S., Hublin, J., Schmitz, R. W., Wilcke, A., Collins, Matthew James, Cappellini, Enrico, Olsen, Jesper Velgaard, Taurozzi, Alberto John & Welker, Frido, 30 Sep 2020, In: Journal of Proteomics. 228, 11 p., 103889.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

      Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

      Research output: Contribution to journalJournal articleResearchpeer-review

    13. Published

      Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function

      Lin, T., Gombos, L., Neuner, A., Sebastian, D., Olsen, Jesper Velgaard, Hrle, A., Benda, C. & Schiebel, E., 2011, In: P L o S One. 6, 5, p. e19700

      Research output: Contribution to journalJournal articleResearchpeer-review

    14. Published

      Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation

      Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Quantitative proteome comparison of human hearts with those of model organisms

      Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking

      Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer

      Lu, A., Waanders, L. F., Almeida, R., Li, G., Allen, M., Cox, J., Olsen, Jesper Velgaard, Bonaldi, T. & Mann, Matthias, 1 Dec 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 158-167 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      ETD-Based Proteomic Profiling Improves Arginine Methylation Identification and Reveals Novel PRMT5 Substrates

      Lu, L., Ye, Z., Zhang, R., Olsen, Jesper Velgaard, Yuan, Y. & Mao, Y., 2024, In: Journal of Proteome Research. 23, 3, p. 1014-1027

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Phosphoproteomics taken to heart

      Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In: Cell Cycle. 12, 17, p. 2707-2708 2 p.

      Research output: Contribution to journalEditorialResearchpeer-review

    20. Published

      Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics

      Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, Daly, M. J., Asselbergs, F. W., van der Harst, P., Milan, D. J., de Bakker, P. I. W., Hansen, K. L., Olsen, Jesper Velgaard & The QT Interval International GWAS Consortium (QT-IGC), T. Q. I. I. G. C. (., 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns

      Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chunaram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In: Cell Reports. 2, 2, p. 419-431 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journalJournal articleResearchpeer-review

    23. Published

      Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues

      Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

      Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      GeLCMS for in-depth protein characterization and advanced analysis of proteomes

      Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    26. Published

      Separation of the gluconeogenic and mitochondrial functions of pgc-1α through s6 kinase

      Lustig, Y., Ruas, J. L., Estall, J. L., Lo, J. C., Devarakonda, S., Laznik, D., Choi, J. H., Spiegelman, B. M., Ono, H. & Olsen, Jesper Velgaard, 15 Jun 2011, In: Genes & Development. 25, 12, p. 1232-1244 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

      Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis

      Macek, B., Mijakovic, I., Olsen, Jesper Velgaard, Gnad, F., Kumar, C., Jensen, P. R. & Mann, Matthias, Feb 2008, In: Molecular and Cellular Proteomics. 6, 4, p. 697-707 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    29. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation

      Macek, B., Gnad, F., Soufi, B., Kumar, C., Olsen, Jesper Velgaard, Mijakovic, I. & Mann, Matthias, 2007, In: Molecular and Cellular Proteomics. 7, 2, p. 299-307 8 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    30. Published

      Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting

      Mackie, Meaghan, Rüther, P. L., Samodova, D., Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In: Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    31. Published

      Combining mass spectrometry and machine learning to discover bioactive peptides

      Madsen, C. T., Refsgaard, J. C., Teufel, F. G., Kjærulff, S. K., Wang, Z., Meng, G., Jessen, C., Heljo, P., Jiang, Q., Zhao, X., Wu, B., Zhou, X., Tang, Y., Jeppesen, J. F., Kelstrup, C. D., Buckley, S. T., Tullin, S., Nygaard-Jensen, J., Chen, X., Zhang, F. & 4 others, Olsen, Jesper Velgaard, Han, D., Grønborg, M. & de Lichtenberg, U., 2022, In: Nature Communications. 13, 17 p., 6235.

      Research output: Contribution to journalJournal articleResearchpeer-review

    32. Published

      The feasibility of palaeoproteomics for studying ancient hominins from South Africa

      Madupe, Palesa Petunia, Hlazo, N., Ruther, P. L., Mackie, Meaghan, Welker, Frido, Ramos Madrigal, Jazmin, Patramanis, Ioannis, Racimo, Fernando, Schroeder, L., Olsen, Jesper Velgaard, Ackermann, R. R. & Cappellini, Enrico, 2022, In: American journal of biological anthropology. 177, S73, p. 112 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    33. Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis

      Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    34. Proteomic analysis of the acid-soluble organic matrix of the chicken calcified eggshell layer

      Mann, K., Macek, B. & Olsen, Jesper Velgaard, 2006, In: Proteomics. 6, 13, p. 3801-10 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    35. Phosphoproteins of the chicken eggshell calcified layer

      Mann, K., Olsen, Jesper Velgaard, Macek, B., Gnad, F. & Mann, Matthias, 2007, In: Proteomics. 7, 1, p. 106-15 9 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    36. Published

      Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.

      Research output: Working paperPreprintResearch

    37. Published

      Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.

      Research output: Contribution to journalJournal articleResearchpeer-review

    38. Published

      Data Processing and Analysis for DIA-Based Phosphoproteomics Using Spectronaut

      Martinez Del Val, Ana, Bekker-Jensen, D. B., Hogrebe, A. & Olsen, Jesper Velgaard, 2021, Proteomics Data Analysis. Cecconi, D. (ed.). Springer, p. 95-107 13 p. (Methods in Molecular Biology, Vol. 2361).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    39. Published

      Obtaining Complete Human Proteomes

      Martinez Del Val, Ana, Hernández Guzmán, Ulises & Olsen, Jesper Velgaard, 2022, In: Annual Review of Genomics and Human Genetics. 23, p. 10.1-10.23 23 p.

      Research output: Contribution to journalReviewResearchpeer-review

    40. Published

      Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids

      Martinez Del Val, Ana, Fort, K., Koenig, Claire, van der Hoeven, Leander Roeland, Franciosa, Giulia, Moehring, T., Ishihama, Y., Chen, Y. J., Makarov, A., Xuan, Y. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 18 p., 3599.

      Research output: Contribution to journalJournal articleResearchpeer-review

    41. Published

      Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function

      Małecki, J. M., Odonohue, M., Kim, Y., Jakobsson, M. E., Gessa, L., Pinto, R., Wu, J., Davydova, E., Moen, A., Olsen, Jesper Velgaard, Thiede, B., Gleizes, P., Leidel, S. A. & Falnes, P. Ø., 2021, In: Nucleic Acids Research. 49, 6, p. 3185-3203 19 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    42. Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics

      Mertins, P., Eberl, H. C., Renkawitz, J., Olsen, Jesper Velgaard, Tremblay, M. L., Mann, M., Ullrich, A. & Daub, H., 2008, In: Molecular and Cellular Proteomics. 7, 9, p. 1763-77 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    43. Published

      Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data

      Larsen, Christian Mirian, Thastrup, M., Mathiasen, R., Schmiegelow, Kjeld, Olsen, Jesper Velgaard & Østergaard, Ole, 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.

      Research output: Contribution to journalReviewResearchpeer-review

    44. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

      Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    45. MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

      Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.

      Research output: Contribution to journalJournal articleResearchpeer-review

    46. Published

      Molecular basis of Tousled-Like Kinase 2 activation

      Mortuza, G. B., Hermida, D., Pedersen, A., Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

      Research output: Contribution to journalJournal articleResearchpeer-review

    47. Published

      From Phosphosites to Kinases

      Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    48. Published

      Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

      Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    49. Published

      Systems Analysis for Interpretation of Phosphoproteomics Data

      Munk, S., Refsgaard, J. C. & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 341-60 20 p. (Methods in molecular biology (Clifton, N.J.)).

      Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

    50. Published

      Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification

      Mylopotamitaki, Dorothea, Harking, F. S., Taurozzi, Alberto John, Fagernäs, Zandra Selina, Godinho, R. M., Smith, G. M., Weiss, M., Schüler, T., McPherron, S. P., Meller, H., Cascalheira, J., Bicho, N., Olsen, Jesper Velgaard, Hublin, J. & Welker, Frido, 2023, In: Scientific Reports. 13, 14 p., 18345.

      Research output: Contribution to journalJournal articleResearchpeer-review

    ID: 9925376