Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)
Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Limits for resolving isobaric tandem mass tag reporter ions using phase constrained spectrum deconvolution
Kelstrup, C. D., Aizikov, K., Batth, Tanveer Singh, Kreutzman, A., Grinfeld, D., Lange, O., Mourad, D., Makarov, A. A. & Olsen, Jesper Velgaard, 2 Nov 2018, In: Journal of Proteome Research. 17, 11, p. 4008-4016 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures
Kjær, I., Lindsted, T., Fröhlich, C., Olsen, Jesper Velgaard, Horak, I. D., Kragh, M. & Pedersen, M. W., Jul 2016, In: Molecular Cancer Therapeutics. 15, 7, p. 1614-1626 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
The low molecular weight proteome of Halobacterium salinarum
Klein, C., Aivaliotis, M., Olsen, Jesper Velgaard, Falb, M., Besir, H., Scheffer, B., Bisle, B., Tebbe, A., Konstantinidis, K., Siedler, F., Pfeiffer, F., Mann, Matthias & Oesterhelt, D., 2007, In: Journal of Proteome Research. 6, 4, p. 1510-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ubc9 sumoylation regulates SUMO target discrimination
Knipscheer, P., Flotho, A., Klug, H., Olsen, Jesper Velgaard, van Dijk, W. J., Fish, A., Johnson, E. S., Mann, M., Sixma, T. K. & Pichler, A., 2008, In: Molecular Cell. 31, 3, p. 371-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation
Knipscheer, P., van Dijk, W. J., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: EMBO Journal. 26, 11, p. 2797-807 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for high-throughput semi-automated label-free- or TMT-based phosphoproteome profiling
Koenig, Claire, Martinez Del Val, Ana, Naicker, P., Stoychev, S., Jordaan, J. & Olsen, Jesper Velgaard, 2023, In: STAR Protocols. 4, 3, 30 p., 102536.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing
Koenig, Claire, Martinez-Val, A., Franciosa, Giulia & Olsen, Jesper Velgaard, 2022, In: Proteomics. 22, 19-20, 13 p., 2100245.Research output: Contribution to journal › Journal article › Research › peer-review
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A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment
Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290Research output: Contribution to journal › Journal article › Research › peer-review
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Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-protease analysis of Pleistocene bone proteomes
Lanigan, Liam Thomas, Mackie, Meaghan, Feine, S., Hublin, J., Schmitz, R. W., Wilcke, A., Collins, Matthew James, Cappellini, Enrico, Olsen, Jesper Velgaard, Taurozzi, Alberto John & Welker, Frido, 30 Sep 2020, In: Journal of Proteomics. 228, 11 p., 103889.Research output: Contribution to journal › Journal article › Research › peer-review
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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphorylation of the yeast γ-tubulin Tub4 regulates microtubule function
Lin, T., Gombos, L., Neuner, A., Sebastian, D., Olsen, Jesper Velgaard, Hrle, A., Benda, C. & Schiebel, E., 2011, In: P L o S One. 6, 5, p. e19700Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation
Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer
Lu, A., Waanders, L. F., Almeida, R., Li, G., Allen, M., Cox, J., Olsen, Jesper Velgaard, Bonaldi, T. & Mann, Matthias, 1 Dec 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 158-167 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ETD-Based Proteomic Profiling Improves Arginine Methylation Identification and Reveals Novel PRMT5 Substrates
Lu, L., Ye, Z., Zhang, R., Olsen, Jesper Velgaard, Yuan, Y. & Mao, Y., 2024, In: Journal of Proteome Research. 23, 3, p. 1014-1027Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphoproteomics taken to heart
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Sep 2013, In: Cell Cycle. 12, 17, p. 2707-2708 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, , 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chunaram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In: Cell Reports. 2, 2, p. 419-431 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.Research output: Contribution to journal › Journal article › Research › peer-review
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In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling
Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GeLCMS for in-depth protein characterization and advanced analysis of proteomes
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Separation of the gluconeogenic and mitochondrial functions of pgc-1α through s6 kinase
Lustig, Y., Ruas, J. L., Estall, J. L., Lo, J. C., Devarakonda, S., Laznik, D., Choi, J. H., Spiegelman, B. M., Ono, H. & Olsen, Jesper Velgaard, 15 Jun 2011, In: Genes & Development. 25, 12, p. 1232-1244 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis
Macek, B., Mijakovic, I., Olsen, Jesper Velgaard, Gnad, F., Kumar, C., Jensen, P. R. & Mann, Matthias, Feb 2008, In: Molecular and Cellular Proteomics. 6, 4, p. 697-707 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
Macek, B., Gnad, F., Soufi, B., Kumar, C., Olsen, Jesper Velgaard, Mijakovic, I. & Mann, Matthias, 2007, In: Molecular and Cellular Proteomics. 7, 2, p. 299-307 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting
Mackie, Meaghan, Rüther, P. L., Samodova, D., Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In: Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining mass spectrometry and machine learning to discover bioactive peptides
Madsen, C. T., Refsgaard, J. C., Teufel, F. G., Kjærulff, S. K., Wang, Z., Meng, G., Jessen, C., Heljo, P., Jiang, Q., Zhao, X., Wu, B., Zhou, X., Tang, Y., Jeppesen, J. F., Kelstrup, C. D., Buckley, S. T., Tullin, S., Nygaard-Jensen, J., Chen, X., Zhang, F. & 4 others, , 2022, In: Nature Communications. 13, 17 p., 6235.Research output: Contribution to journal › Journal article › Research › peer-review
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The feasibility of palaeoproteomics for studying ancient hominins from South Africa
Madupe, Palesa Petunia, Hlazo, N., Ruther, P. L., Mackie, Meaghan, Welker, Frido, Ramos Madrigal, Jazmin, Patramanis, Ioannis, Racimo, Fernando, Schroeder, L., Olsen, Jesper Velgaard, Ackermann, R. R. & Cappellini, Enrico, 2022, In: American journal of biological anthropology. 177, S73, p. 112 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis
Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomic analysis of the acid-soluble organic matrix of the chicken calcified eggshell layer
Mann, K., Macek, B. & Olsen, Jesper Velgaard, 2006, In: Proteomics. 6, 13, p. 3801-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphoproteins of the chicken eggshell calcified layer
Mann, K., Olsen, Jesper Velgaard, Macek, B., Gnad, F. & Mann, Matthias, 2007, In: Proteomics. 7, 1, p. 106-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.Research output: Working paper › Preprint › Research
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Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
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Data Processing and Analysis for DIA-Based Phosphoproteomics Using Spectronaut
Martinez Del Val, Ana, Bekker-Jensen, D. B., Hogrebe, A. & Olsen, Jesper Velgaard, 2021, Proteomics Data Analysis. Cecconi, D. (ed.). Springer, p. 95-107 13 p. (Methods in Molecular Biology, Vol. 2361).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Obtaining Complete Human Proteomes
Martinez Del Val, Ana, Hernández Guzmán, Ulises & Olsen, Jesper Velgaard, 2022, In: Annual Review of Genomics and Human Genetics. 23, p. 10.1-10.23 23 p.Research output: Contribution to journal › Review › Research › peer-review
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Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids
Martinez Del Val, Ana, Fort, K., Koenig, Claire, van der Hoeven, Leander Roeland, Franciosa, Giulia, Moehring, T., Ishihama, Y., Chen, Y. J., Makarov, A., Xuan, Y. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
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Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Małecki, J. M., Odonohue, M., Kim, Y., Jakobsson, M. E., Gessa, L., Pinto, R., Wu, J., Davydova, E., Moen, A., Olsen, Jesper Velgaard, Thiede, B., Gleizes, P., Leidel, S. A. & Falnes, P. Ø., 2021, In: Nucleic Acids Research. 49, 6, p. 3185-3203 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics
Mertins, P., Eberl, H. C., Renkawitz, J., Olsen, Jesper Velgaard, Tremblay, M. L., Mann, M., Ullrich, A. & Daub, H., 2008, In: Molecular and Cellular Proteomics. 7, 9, p. 1763-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mass spectrometry-based proteomics of cerebrospinal fluid in pediatric central nervous system malignancies: a systematic review with meta-analysis of individual patient data
Larsen, Christian Mirian, Thastrup, M., Mathiasen, R., Schmiegelow, Kjeld, Olsen, Jesper Velgaard & Østergaard, Ole, 2024, In: Fluids and Barriers of the CNS. 21, 17 p., 14.Research output: Contribution to journal › Review › Research › peer-review
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics
Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis of Tousled-Like Kinase 2 activation
Mortuza, G. B., Hermida, D., Pedersen, A., Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.Research output: Contribution to journal › Journal article › Research › peer-review
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From Phosphosites to Kinases
Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress
Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systems Analysis for Interpretation of Phosphoproteomics Data
Munk, S., Refsgaard, J. C. & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 341-60 20 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification
Mylopotamitaki, Dorothea, Harking, F. S., Taurozzi, Alberto John, Fagernäs, Zandra Selina, Godinho, R. M., Smith, G. M., Weiss, M., Schüler, T., McPherron, S. P., Meller, H., Cascalheira, J., Bicho, N., Olsen, Jesper Velgaard, Hublin, J. & Welker, Frido, 2023, In: Scientific Reports. 13, 14 p., 18345.Research output: Contribution to journal › Journal article › Research › peer-review
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Homo sapiens reached the higher latitudes of Europe by 45,000 years ago
Mylopotamitaki, D., Weiss, M., Fewlass, H., Zavala, E. I., Rougier, H., Sümer, A. P., Hajdinjak, M., Smith, G. M., Ruebens, K., Sinet-Mathiot, V., Pederzani, S., Essel, E., Harking, F. S., Xia, H., Hansen, J., Kirchner, A., Lauer, T., Stahlschmidt, M., Hein, M., Talamo, S. & 13 others, , 2024, In: Nature. 626, 7998, p. 341-346Research output: Contribution to journal › Journal article › Research › peer-review
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Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
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Feasibility of large-scale phosphoproteomics with higher energy collisional dissociation fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, M., 3 Dec 2010, In: Journal of Proteome Research. 9, 12, p. 6786-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Matrix Gla Protein drives stemness and tumor initiation in ovarian cancer
Nieddu, V., Melocchi, V., Battistini, C., Franciosa, Giulia, Lupia, M., Stellato, C., Bertalot, G., Olsen, Jesper Velgaard, Colombo, N., Bianchi, F. & Cavallaro, U., 2023, In: Cell Death and Disease. 14, 3, 16 p., 220.Research output: Contribution to journal › Journal article › Research › peer-review
Intramolecular hydrogen atom transfer in hydrogen-deficient polypeptide radical cations
Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F., Olsen, Jesper Velgaard & Zubarev, R. A., 2000, In: Chemical Physics Letters. 330, 5-6, p. 558-562 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomic mapping of brain plasma membrane proteins
Nielsen, P. A., Olsen, Jesper Velgaard, Podtelejnikov, A. V., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 402-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells
Niss, K., Jakobsson, M. E., Westergaard, David, Belling, K. G., Olsen, Jesper Velgaard & Brunak, Søren, 2020, In: Molecular and Cellular Endocrinology. 517, 9 p., 110923.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of the golgi apparatus by p38 and JNK kinases during cellular stress responses
Nordgaard, C., Tollenaere, M. A. X., Martinez Del Val, Ana, Bekker-Jensen, D. B., Blasius, Melanie, Olsen, Jesper Velgaard & Bekker-Jensen, Simon Holst, 2021, In: International Journal of Molecular Sciences. 22, 17, 23 p., 9595.Research output: Contribution to journal › Journal article › Research › peer-review
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ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
Notenboom, V., Hibbert, R. G., van Rossum-Fikkert, S. E., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: Nucleic Acids Research. 35, 17, p. 5819-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Status of large-scale analysis of post-translational modifications by mass spectrometry
Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In: Molecular & Cellular Proteomics. 12, p. 3444-52Research output: Contribution to journal › Journal article › Research › peer-review
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Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community
Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In: Science Signaling. 4, 160, p. pe7Research output: Contribution to journal › Journal article › Research › peer-review
High accuracy mass spectrometry in large-scale analysis of protein phosphorylation
Olsen, Jesper Velgaard & Macek, B., 2009, In: Methods in Molecular Biology. 492, p. 131-42 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids
Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In: Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain
Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Higher-energy C-trap dissociation for peptide modification analysis
Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative proteomic profiling of membrane proteins from the mouse brain cortex, hippocampus, and cerebellum using the HysTag reagent: mapping of neurotransmitter receptors and ion channels
Olsen, Jesper Velgaard, Nielsen, P. A., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2007, In: Brain Research. 1134, 1, p. 95-106 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Trypsin cleaves exclusively C-terminal to arginine and lysine residues
Olsen, Jesper Velgaard, Ong, S. & Mann, Matthias, 2004, In: Molecular and Cellular Proteomics. 3, 6, p. 608-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap
Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation
Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Large-scale proteomics analysis of the human kinome
Oppermann, F. S., Gnad, F., Olsen, Jesper Velgaard, Hornberger, R., Greff, Z., Kéri, G., Mann, M. & Daub, H., 2009, In: Molecular and Cellular Proteomics. 8, 7, p. 1751-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, , 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors
Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis
Papadopoulou, D., Roumelioti, F., Tzaferis, C., Chouvardas, P., Pedersen, A., Charalampous, F., Christodoulou-Vafeiadou, E., Ntari, L., Karagianni, N., Denis, M. C., Olsen, Jesper Velgaard, Matralis, A. N. & Kollias, G., 2023, In: JCI insight. 8, 9, 18 p., e165024.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation
Paul, I., Batth, Tanveer Singh, Iglesias Gato, Diego, Al-Araimi, A., Al-Haddabi, I., Alkharusi, A., Norstedt, G., Olsen, Jesper Velgaard, Zadjali, F. & Flores-Morales, A., 2017, In: Scientific Reports. 7, 14 p., 42800.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
Pedersen, A., Pfeiffer, A., Karemore, G., Akimov, V., Bekker-Jensen, D. B., Blagoev, B., Francavilla, C. & Olsen, Jesper Velgaard, 2021, In: iScience. 24, 4, 34 p., 102321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)
Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing Linear Ion-Trap Data-Independent Acquisition toward Single-Cell Proteomics
Phlairaharn, T., Ye, Z., Krismer, Elena, Pedersen, A. K., Pietzner, M., Olsen, Jesper Velgaard, Schoof, E. M. & Searle, B. C., 2023, In: Analytical Chemistry. 95, 26, p. 9881-9891 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma
Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
Pichler, A., Knipscheer, P., Oberhofer, E., van Dijk, W. J., Körner, R., Olsen, Jesper Velgaard, Jentsch, S., Melchior, F. & Sixma, T. K., 2005, In: Nature Structural and Molecular Biology. 12, 3, p. 264-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells
Pines, A., Kelstrup, C. D., Vrouwe, M. G., Puigvert, J. C., Typas, D., Misovic, B., de Groot, A., von Stechow, L., van de Water, B., Danen, E. H. J., Vrieling, H., Mullenders, L. H. F. & Olsen, Jesper Velgaard, 2011, In: Molecular and Cellular Biology. 31, 24, p. 4964-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Pinto, R., Vågbø, C. B., Jakobsson, M. E., Kim, Y., Baltissen, M. P., O'Donohue, M., Hernández Guzmán, Ulises, Małecki, J. M., Wu, J., Kirpekar, F., Olsen, Jesper Velgaard, Gleizes, P., Vermeulen, M., Leidel, S. A., Slupphaug, G. & Falnes, P. Ø., 2020, In: Nucleic Acids Research. 48, 2, p. 830-846 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation
Pirone, L., Xolalpa, W., Sigurdsson, J. O., Ramirez, J., Pérez, C., González, M., de Sabando, A. R., Elortza, F., Rodriguez, M. S., Mayor, U., Olsen, Jesper Velgaard, Barrio, R. & Sutherland, J. D., 2017, In: Scientific Reports. 7, 17 p., 40756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Palaeoproteomics resolves sloth relationships
Presslee, S., Slater, G. J., Pujos, F., Forasiepi, A. M., Fischer, R., Molloy, K., Mackie, M., Olsen, J. V., Kramarz, A., Taglioretti, M., Scaglia, F., Lezcano, M., Lanata, J. L., Southon, J., Feranec, R., Bloch, J., Hajduk, A., Martin, F. M., Salas Gismondi, R., Reguero, M. & 6 others, , 2019, In: Nature Ecology & Evolution. 3, p. 1121-1130Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immature truncated O-glycophenotype of cancer directly induces oncogenic features
Radhakrishnan, P., Dabelsteen, S., Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, C., Vakhrushev, S. Y., Olsen, J. V., Hansen, L., Bennett, E. P., Woetmann, A., Yin, G., Chen, L., Song, H., Bak, M., Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, K. & 4 others, , 12 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combinatorial Drug Screening Identifies Ewing Sarcoma–specific Sensitivities
Radic-Sarikas, B., Tsafou, K. P., Emdal, Kristina Bennet, Papamarkou, T., Huber, K. V. M., Mutz, C., Toretsky, J. A., Bennett, K. L., Olsen, Jesper Velgaard, Brunak, S., Kovar, H. & Superti-Furga, G., Jan 2017, In: Molecular Cancer Therapeutics. 16, 1, p. 88-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PRIME-XS, a European infrastructure for proteomics
Raijmakers, R., Olsen, Jesper Velgaard, Aebersold, R. & Heck, A. J. R., 23 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1901-1904 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., Pedersen, J. S., Kuhlmann, Tine Plato, Hansen, F., Olsen, Jesper Velgaard, Pfeiffer, P., Ørntoft, T. F. & Andersen, C. L., 2016, In: Nature Communications. 7, 15 p., 12436.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3
Ronkina, N., Shushakova, N., Tiedje, C., Yakovleva, T., Tollenaere, M. A. X., Scott, A., Batth, Tanveer Singh, Olsen, Jesper Velgaard, Helmke, A., Bekker-Jensen, Simon Holst, Clark, A. R., Kotlyarov, A. & Gaestel, M., 2019, In: Journal of immunology (Baltimore, Md. : 1950). 203, 8, p. 2291-2300 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression and secretion of a lytic polysaccharide monooxygenase by a fast-growing cyanobacterium
Russo, D. A., Zedler, J. A. Z., Wittmann, D. N., Möllers, B., Singh, R. K., Batth, Tanveer Singh, van Oort, B., Olsen, Jesper Velgaard, Bjerrum, Morten Jannik & Jensen, Poul Erik, 2019, In: Biotechnology for Biofuels. 12, 1, 13 p., 74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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