Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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52 Genetic Loci Influencing Myocardial Mass
van der Harst, P., van Setten, J., Verweij, N., Vogler, G., Franke, L., Maurano, M. T., Wang, X., Mateo Leach, I., Eijgelsheim, M., Sotoodehnia, N., Hayward, C., Sorice, R., Meirelles, O., Lyytikäinen, L-P., Polašek, O., Tanaka, T., Arking, D. E., Ulivi, S., Trompet, S., Müller-Nurasyid, M. & 140 others, , 27 Sep 2016, In: Journal of the American College of Cardiology. 68, 13, p. 1435-48 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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FRMD6 has tumor suppressor functions in prostate cancer
Haldrup, J., Strand, S. H., Cieza-Borrella, C., Jakobsson, M. E., Riedel, M., Norgaard, M., Hedensted, S., Dagnaes-Hansen, F., Ulhoi, B. P., Eeles, R., Borre, M., Olsen, Jesper Velgaard, Thomsen, M., Kote-Jarai, Z. & Sorensen, K. D., 2021, In: Oncogene. 40, p. 763-776 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Homo sapiens reached the higher latitudes of Europe by 45,000 years ago
Mylopotamitaki, D., Weiss, M., Fewlass, H., Zavala, E. I., Rougier, H., Sümer, A. P., Hajdinjak, M., Smith, G. M., Ruebens, K., Sinet-Mathiot, V., Pederzani, S., Essel, E., Harking, F. S., Xia, H., Hansen, J., Kirchner, A., Lauer, T., Stahlschmidt, M., Hein, M., Talamo, S. & 13 others, , 2024, In: Nature. 626, 7998, p. 341-346Research output: Contribution to journal › Journal article › Research › peer-review
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In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, Diego, Kruse, Thomas, Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, Jesper Velgaard & Flores Morales, A., 2015, In: Oncogene. 34, p. 2764–2776 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., Pedersen, J. S., Kuhlmann, Tine Plato, Hansen, F., Olsen, Jesper Velgaard, Pfeiffer, P., Ørntoft, T. F. & Andersen, C. L., 2016, In: Nature Communications. 7, 15 p., 12436.Research output: Contribution to journal › Journal article › Research › peer-review
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A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients
Bekker-Jensen, D. B., Martinez Del Val, Ana, Steigerwald, S., Rüther, P., Fort, K. L., Arrey, T. N., Harder, A., Makarov, A. & Olsen, Jesper Velgaard, 2020, In: Molecular and Cellular Proteomics. 19, 4, p. 716-729 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin
Egerod, Kristoffer Lihme, Engelstoft, M. S., Grunddal, Kaare Villum, Nøhr, M. K., Secher, A., Sakata, I., Pedersen, Jens, Windeløv, Johanne Agerlin, Füchtbauer, E., Olsen, Jørgen, Sundler, F., Christensen, Jan Pravsgaard, Wierup, N., Olsen, Jesper Velgaard, Holst, Jens Juul, Zigman, J. M., Poulsen, Steen Seier & Schwartz, Thue W., 1 Dec 2012, In: Endocrinology. 153, 12, p. 5782-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos
Demeter, F., Zanolli, C., Westaway, K. E., Joannes-Boyau, R., Duringer, P., Morley, M. W., Welker, F., Rüther, P. L., Skinner, M. M., McColl, H., Gaunitz, C., Vinner, L., Dunn, T. E., Olsen, J. V., Sikora, M., Ponche, J-L., Suzzoni, E., Frangeul, S., Boesch, Q., Antoine, P-O. & 20 others, , 2022, In: Nature Communications. 13, 17 p., 2557.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation
Pirone, L., Xolalpa, W., Sigurdsson, J. O., Ramirez, J., Pérez, C., González, M., de Sabando, A. R., Elortza, F., Rodriguez, M. S., Mayor, U., Olsen, Jesper Velgaard, Barrio, R. & Sutherland, J. D., 2017, In: Scientific Reports. 7, 17 p., 40756.Research output: Contribution to journal › Journal article › Research › peer-review
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A deeper look at carrier proteome effects for single-cell proteomics
Ye, Z., Batth, Tanveer Singh, Rüther, P. & Olsen, Jesper Velgaard, 2022, In: Communications Biology . 5, 8 p., 150.Research output: Contribution to journal › Journal article › Research › peer-review
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A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment
Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290Research output: Contribution to journal › Journal article › Research › peer-review
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
A mass spectrometry-friendly database for cSNP identification
Schandorff, S., Olsen, Jesper Velgaard, Bunkenborg, J., Blagoev, B., Zhang, Y., Andersen, J. S. & Mann, Matthias, 2007, In: Nature Methods. 4, 6, p. 465-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics
Bache, N., Geyer, P. E., Bekker-Jensen, D. B., Hørning, O., Falkenby, L., Treit, P. V., Doll, S., Paron, I., Müller, J. B., Meier, F., Olsen, Jesper Velgaard, Vorm, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 11, p. 2284-2296 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
A practical guide to the MaxQuant computational platform for SILAC-based quantitative proteomics
Cox, J., Matic, I., Hilger, M., Nagaraj, N., Selbach, M., Olsen, Jesper Velgaard & Mann, M., 2009, In: Nature Protocols (Print Edition). 4, 5, p. 698-705 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A seven-transmembrane methyltransferase catalysing N-terminal histidine methylation of lytic polysaccharide monooxygenases
Batth, Tanveer Singh, Simonsen, J. L., Hernandez Rollan, Cristina, Brander, Søren, Morth, J. P., Johansen, Katja Salomon, Nørholm, M. H. H., Hoof, J. B. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 15 p., 4202.Research output: Contribution to journal › Journal article › Research › peer-review
Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry
Haselmann, K. F., Budnik, B. A., Olsen, Jesper Velgaard, Nielsen, Michael Lund, Reis, C. A., Clausen, H., Johnsen, A. H. & Zubarev, R. A., 2001, In: Analytical Chemistry. 73, 13, p. 2998-3005 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
Trulley, P., Snieckute, Goda, Bekker-Jensen, D., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2019, In: Cell Reports. 27, 10, p. 2859-2870.e6 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2
Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).Research output: Working paper › Preprint › Research
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In: Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of Changes in SUMO-2/3 Modification during Breast Cancer Progression and Metastasis
Subramonian, D., Raghunayakula, S., Olsen, Jesper Velgaard, Beningo, K. A., Paschen, W. & Zhang, X., Sep 2014, In: Journal of Proteome Research. 13, 9, p. 3905–3918 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analytic framework for peptidomics applied to large-scale neuropeptide identification
Secher, A., Kelstrup, C. D., Conde-Frieboes, K. W., Pyke, C., Raun, K., Wulff, B. S. & Olsen, Jesper Velgaard, 2016, In: Nature Communications. 7, 10 p., 11436.Research output: Contribution to journal › Journal article › Research › peer-review
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Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)
Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient biomolecules reveal ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from Sicily
Scorrano, Gabriele, Nielsen, S. H., Lo Vetro, D., Mackie, Meaghan, Fabbri, P. F., Allentoft, Morten Erik, Martini, F., Martanez-Labarga, C., Rickards, O., Olsen, Jesper Velgaard, Willerslev, Eske, Cappellini, Enrico & Sikora, Martin, 2020, p. 255-255.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers
Hendy, J., Colonese, A. C., Franz, I., Fernandes, R., Fischer, R., Orton, D., Lucquin, A., Spindler, L., Anvari, J., Stroud, E., Biehl, P. F., Speller, C., Boivin, N., Mackie, Meaghan, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Collins, Matthew James, Craig, O. E. & Rosenstock, E., 1 Dec 2018, In: Nature Communications. 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient proteins resolve the evolutionary history of Darwin's South American ungulates
Welker, F., Collins, M. J., Thomas, J. A., Wadsley, M., Brace, S., Cappellini, E., Turvey, S. T., Reguero, M., Gelfo, J. N., Kramarz, A., Burger, J., Thomas-Oates, J., Ashford, D. A., Ashton, P. D., Rowsell, K., Porter, D. M., Kessler, B., Fischer, R., Baessmann, C., Kaspar, S. & 11 others, , 4 Jun 2015, In: Nature. 522, 7554, p. 81–84 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Andromeda - a peptide search engine integrated into the MaxQuant environment
Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, Jesper Velgaard & Mann, Matthias, 1 Apr 2011, In: Journal of Proteome Research. 10, 4, p. 1794-805 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Annotation of loci from genome-wide association studies using tissue-specific quantitative interaction proteomics
Lundby, A., Rossin, E. J., Steffensen, A. B., Acha, M. R., Newton-Cheh, C., Pfeufer, A., Lynch, S. N., Olesen, S-P., Brunak, S., Ellinor, P. T., Jukema, J. W., Trompet, S., Ford, I., Macfarlane, P. W., Krijthe, B. P., Hofman, A., Uitterlinden, A. G., Stricker, B. H., Nathoe, H. M., Spiering, W. & 8 others, , 22 Jun 2014, In: Nature Methods. 11, 8, p. 868-874 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation
Warner, H., Franciosa, Giulia, van der Borg, G., Coenen, B., Faas, Felix, Koenig, Claire, de Boer, R., Classens, R., Maassen, S., Baranov, M. V., Mahajan, S., Dabral, D., Bianchi, F., van Hilten, N., Risselada, H. J., Roos, W. H., Olsen, Jesper Velgaard, Cano, L. Q. & van den Bogaart, G., 2024, In: Cell Reports. 43, 3, 28 p., 113866.Research output: Contribution to journal › Journal article › Research › peer-review
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B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)
Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Benchmarking common quantification strategies for large-scale phosphoproteomics
Hogrebe, A., von Stechow, L., Bekker-Jensen, D. B., Weinert, B. T., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, 1, p. 1-13 1045.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
Can relative cleavage frequencies in peptides provide additional sequence information?
Budnik, B. A., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Haselmann, K. F., Horth, P., Haehnel, W. & Zubarev, R. A., 2002, In: International Journal of Mass Spectrometry. 219, 1, p. 283-294 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.Research output: Contribution to journal › Journal article › Research › peer-review
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Cetuximab Resistance in Squamous Carcinomas of the Upper Aerodigestive Tract Is Driven by Receptor Tyrosine Kinase Plasticity: Potential for mAb Mixtures
Kjær, I., Lindsted, T., Fröhlich, C., Olsen, Jesper Velgaard, Horak, I. D., Kragh, M. & Pedersen, M. W., Jul 2016, In: Molecular Cancer Therapeutics. 15, 7, p. 1614-1626 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth
Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.Research output: Contribution to journal › Journal article › Research › peer-review
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Combinatorial Drug Screening Identifies Ewing Sarcoma–specific Sensitivities
Radic-Sarikas, B., Tsafou, K. P., Emdal, Kristina Bennet, Papamarkou, T., Huber, K. V. M., Mutz, C., Toretsky, J. A., Bennett, K. L., Olsen, Jesper Velgaard, Brunak, S., Kovar, H. & Superti-Furga, G., Jan 2017, In: Molecular Cancer Therapeutics. 16, 1, p. 88-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combining mass spectrometry and machine learning to discover bioactive peptides
Madsen, C. T., Refsgaard, J. C., Teufel, F. G., Kjærulff, S. K., Wang, Z., Meng, G., Jessen, C., Heljo, P., Jiang, Q., Zhao, X., Wu, B., Zhou, X., Tang, Y., Jeppesen, J. F., Kelstrup, C. D., Buckley, S. T., Tullin, S., Nygaard-Jensen, J., Chen, X., Zhang, F. & 4 others, , 2022, In: Nature Communications. 13, 17 p., 6235.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparing extraction method efficiency for high-throughput palaeoproteomic bone species identification
Mylopotamitaki, Dorothea, Harking, F. S., Taurozzi, Alberto John, Fagernäs, Zandra Selina, Godinho, R. M., Smith, G. M., Weiss, M., Schüler, T., McPherron, S. P., Meller, H., Cascalheira, J., Bicho, N., Olsen, Jesper Velgaard, Hublin, J. & Welker, Frido, 2023, In: Scientific Reports. 13, 14 p., 18345.Research output: Contribution to journal › Journal article › Research › peer-review
Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids
Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In: Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Complete Mapping of Complex Disulfide Patterns with Closely-Spaced Cysteines by In-Source Reduction and Data-Dependent Mass Spectrometry
Cramer, C. N., Kelstrup, C. D., Olsen, Jesper Velgaard, Haselmann, K. F. & Nielsen, P. K., 6 Jun 2017, In: Analytical Chemistry. 89, 11, p. 5949-5957 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)
Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
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Ctk1 function is necessary for full translation initiation activity in Saccharomyces cerevisiae
Coordes, B., Brünger, K. M., Burger, K., Soufi, B., Horenk, J., Eick, D., Olsen, Jesper Velgaard & Sträßer, K., Jan 2015, In: Eukaryotic Cell (Online Edition). 14, 1, p. 86 95 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor
Sanchez-Quiles, V., Akimov, V., Osinalde, N., Francavilla, C., Puglia, M., Barrio-Hernandez, I., Kratchmarova, I., Olsen, Jesper Velgaard & Blagoev, B., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1433-1446 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Data Processing and Analysis for DIA-Based Phosphoproteomics Using Spectronaut
Martinez Del Val, Ana, Bekker-Jensen, D. B., Hogrebe, A. & Olsen, Jesper Velgaard, 2021, Proteomics Data Analysis. Cecconi, D. (ed.). Springer, p. 95-107 13 p. (Methods in Molecular Biology, Vol. 2361).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
De novo sequencing of antimicrobial peptides isolated from the venom glands of the wolf spider Lycosa singoriensis
Budnik, B. A., Olsen, Jesper Velgaard, Egorov, T. A., Anisimova, V. E., Galkina, T. G., Musolyamov, A. K., Grishin, E. V. & Zubarev, R. A., 2004, In: Journal of Mass Spectrometry. 39, 2, p. 193-201 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias
Boulanger, M., Aqrouq, M., Tempé, D., Kifagi, C., Ristic, M., Akl, D., Hallal, R., Carusi, A., Gabellier, L., de Toledo, M., Sigurdsson, J-O., Kaoma, T., Andrieu-Soler, C., Forné, T., Soler, E., Hicheri, Y., Gueret, E., Vallar, L., Olsen, J. V., Cartron, G. & 2 others, , 2023, In: Nucleic Acids Research. 51, 16, 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the human phosphoproteome
Franciosa, Giulia, Martinez-Val, A. & Olsen, Jesper Velgaard, 2020, In: Nature Biotechnology. 38, p. 285-286 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel
Taurozzi, Alberto John, Rüther, P. L., Patramanis, Ioannis, Koenig, Claire, Paterson, Ryan Sinclair, Madupe, Palesa Petunia, Harking, F. S., Welker, Frido, Mackie, Meaghan, Ramos Madrigal, Jazmin, Olsen, Jesper Velgaard & Cappellini, Enrico, 2024, (E-pub ahead of print) In: Nature Protocols. 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
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Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases
Fagernäs, Zandra Selina, Troché, Gaudry Bruno, Olsen, Jesper Velgaard & Welker, Frido, 2024, In: Journal of Proteomics. 298, 10 p., 105143.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O., Swallow, D. M., Fotakis, A. K., Christensen, R. J., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Mackie, M., Canci, A., Bouwman, A., Ruhli, F. & 2 others, , 2015, In: American Journal of Physical Anthropology. 156, Suppl. 60, p. 319 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O. E., Swallow, D. M., Fotakis, A. K., Jersie-Christensen, R. R., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Charlton, S., Mackie, M. E., Canci, A., Bouwman, A. & 3 others, , 2014, In: Scientific Reports. 4, 6 p., 7104.Research output: Contribution to journal › Journal article › Research › peer-review
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Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry
Cramer, C. N., Haselmann, K. F., Olsen, Jesper Velgaard & Nielsen, P. K., 2 Feb 2016, In: Analytical Chemistry. 88, 3, p. 1585-1592 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation
Sampadi, B., Vermeulen, S., Mišovic, B., Boei, J. J., Batth, Tanveer Singh, Chang, J. G., Paulsen, M. T., Magnuson, B., Schimmel, J., Kool, H., Olie, C. S., Everts, B., Vertegaal, A. C. O., Olsen, Jesper Velgaard, Ljungman, M., Jeggo, P. A., Mullenders, L. H. F. & Vrieling, H., 2022, In: Cells. 11, 23, 25 p., 3794.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
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ETD-Based Proteomic Profiling Improves Arginine Methylation Identification and Reveals Novel PRMT5 Substrates
Lu, L., Ye, Z., Zhang, R., Olsen, Jesper Velgaard, Yuan, Y. & Mao, Y., 2024, In: Journal of Proteome Research. 23, 3, p. 1014-1027Research output: Contribution to journal › Journal article › Research › peer-review
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Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny
Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Rüther, P. L., Fotakis, A. K., Lyon, D., Moreno-Mayar, J. V., Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, M., Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W., Chan, Y. L., Götherström, A. & 23 others, , 2019, In: Nature. 574, 7776, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
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Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community
Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In: Science Signaling. 4, 160, p. pe7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells
Niss, K., Jakobsson, M. E., Westergaard, David, Belling, K. G., Olsen, Jesper Velgaard & Brunak, Søren, 2020, In: Molecular and Cellular Endocrinology. 517, 9 p., 110923.Research output: Contribution to journal › Journal article › Research › peer-review
Electron capture dissociation of singly and multiply phosphorylated peptides
Stensballe, A., Jensen, O. N., Olsen, Jesper Velgaard, Haselmann, K. F. & Zubarev, R. A., 2000, In: Rapid Communications in Mass Spectrometry. 14, 19, p. 1793-800 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Electronic excitation gives informative fragmentation of polypeptide cations and anions
Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In: European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enamel proteome sequences from Dmanisi (Georgia) enable molecular phylogeny beyond the limits of ancient DNA preservation
Cappellini, Enrico, Welker, Frido, Olsen, Jesper Velgaard, Lordkipanidze, D. & Willerslev, Eske, 2019, In: American Journal of Physical Anthropology. 168, suppl. 68, p. 35 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Enamel proteome shows that Gigantopithecus was an early diverging pongine
Welker, Frido, Ramos Madrigal, Jazmin, Kuhlwilm, M., Liao, W., Gutenbrunner, P., de Manuel, M., Samodova, D., Mackie, Meaghan, Allentoft, Morten Erik, Bacon, A., Collins, Matthew James, Cox, J., Lalueza-Fox, C., Olsen, Jesper Velgaard, Demeter, Fabrice, Wang, W., Marques-Bonet, T. & Cappellini, Enrico, 2019, In: Nature. 576, p. 262-265Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression and secretion of a lytic polysaccharide monooxygenase by a fast-growing cyanobacterium
Russo, D. A., Zedler, J. A. Z., Wittmann, D. N., Möllers, B., Singh, R. K., Batth, Tanveer Singh, van Oort, B., Olsen, Jesper Velgaard, Bjerrum, Morten Jannik & Jensen, Poul Erik, 2019, In: Biotechnology for Biofuels. 12, 1, 13 p., 74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extending the Coverage of Lys-C/Trypsin-Based Bottom-up Proteomics by Cysteine S-Aminoethylation
Tomioka, R., Tomioka, A., Ogata, K., Chan, H. J., Chen, L. Y., Hernández Guzmán, Ulises, Xuan, Y., Olsen, Jesper Velgaard, Chen, Y. J. & Ishihama, Y., 2024, In: Journal of the American Society for Mass Spectrometry. 35, 2, p. 386-396 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Faecal proteomics as a novel method to study mammalian behaviour and physiology
Tsutaya, T., Mackie, Meaghan, Sawafuji, R., Miyabe-Nishiwaki, T., Olsen, Jesper Velgaard & Cappellini, Enrico, 2021, In: Molecular Ecology Resources. 21, 6, p. 1808-1819 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Feasibility of large-scale phosphoproteomics with higher energy collisional dissociation fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, M., 3 Dec 2010, In: Journal of Proteome Research. 9, 12, p. 6786-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From Phosphosites to Kinases
Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
Notenboom, V., Hibbert, R. G., van Rossum-Fikkert, S. E., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: Nucleic Acids Research. 35, 17, p. 5819-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling
Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
Wright, S. C., Motso, A., Koutsilieri, S., Beusch, C. M., Sabatier, Pierre Camille, Berghella, A., Blondel-Tepaz, É., Mangenot, K., Pittarokoilis, I., Sismanoglou, D. C., Le Gouill, C., Olsen, Jesper Velgaard, Zubarev, R. A., Lambert, N. A., Hauser, Alexander Sebastian, Bouvier, M. & Lauschke, V. M., 2023, In: Nature Communications. 14, 1, 13 p., 6243.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GeLCMS for in-depth protein characterization and advanced analysis of proteomes
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Generic Workflow for Mapping of Complex Disulfide Bonds Using In-Source Reduction and Extracted Ion Chromatograms from Data-Dependent Mass Spectrometry
Cramer, C. N., Kelstrup, C., Olsen, Jesper Velgaard, Haselmann, K. F. & Nielsen, P. K., 2018, In: Analytical Chemistry. 90, 13, p. 8202-8210Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M. & 31 others, , 22 Jun 2014, In: Nature Genetics. 46, 8, p. 826-838 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Scorrano, Gabriele, Nielsen, Sofie Holtsmark, Vetro, D. L., Sawafuji, R., Mackie, Meaghan, Margaryan, Ashot, Fotaki, Anna Katerina, Martínez-Labarga, C., Fabbri, P. F., Allentoft, Morten Erik, Carra, M., Martini, F., Rickards, O., Olsen, Jesper Velgaard, Pedersen, Mikkel Winther, Cappellini, Enrico & Sikora, Martin, 2022, In: Communications Biology. 5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells
Galli, G. G., Carrara, M., Francavilla, C., Honnens de Lichtenberg, K., Olsen, Jesper Velgaard, Calogero, R. A. & Lund, Anders H., 16 Sep 2013, In: Molecular and Cellular Biology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and proteomic evidence for Mycobacterium leprae in human medieval dental calculus from Trondheim, Norway
Vagene, A. J., Fotaki, Anna Katerina, Denham, S. D., Orbegozo, M., Mackie, Meaghan, Olsen, Jesper Velgaard, Cappellini, Enrico, Christophersen, A. & Gilbert, M Thomas P, 2020, In: American Journal of Physical Anthropology. 171, p. 291 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Global analysis of the yeast osmotic stress response by quantitative proteomics
Soufi, B., Kelstrup, C. D., Stoehr, G., Fröhlich, F., Walther, T. C. & Olsen, Jesper Velgaard, 2009, In: Molecular BioSystems. 5, 11, p. 1337-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells
Pines, A., Kelstrup, C. D., Vrouwe, M. G., Puigvert, J. C., Typas, D., Misovic, B., de Groot, A., von Stechow, L., van de Water, B., Danen, E. H. J., Vrieling, H., Mullenders, L. H. F. & Olsen, Jesper Velgaard, 2011, In: Molecular and Cellular Biology. 31, 24, p. 4964-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
High accuracy mass spectrometry in large-scale analysis of protein phosphorylation
Olsen, Jesper Velgaard & Macek, B., 2009, In: Methods in Molecular Biology. 492, p. 131-42 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast
Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Proteomics. 9, 20, p. 4642-4652 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Higher-energy C-trap dissociation for peptide modification analysis
Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Jones, M. J. K., Gelot, C., Munk, S., Koren, A., Kawasoe, Y., George, K. A., Santos, R. E., Olsen, Jesper Velgaard, McCarroll, S. A., Frattini, M. G., Takahashi, T. S. & Jallepalli, P. V., 2021, In: Molecular Cell. 81, 3, p. 426-441.e8 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Małecki, J. M., Odonohue, M., Kim, Y., Jakobsson, M. E., Gessa, L., Pinto, R., Wu, J., Davydova, E., Moen, A., Olsen, Jesper Velgaard, Thiede, B., Gleizes, P., Leidel, S. A. & Falnes, P. Ø., 2021, In: Nucleic Acids Research. 49, 6, p. 3185-3203 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids
Martinez Del Val, Ana, Fort, K., Koenig, Claire, van der Hoeven, Leander Roeland, Franciosa, Giulia, Moehring, T., Ishihama, Y., Chen, Y. J., Makarov, A., Xuan, Y. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain
Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of animal species in skin clothing from museum collections
Schmidt, A. L., Gilbert, M Thomas P, Cappellini, Enrico & Olsen, Jesper Velgaard, 2011. 8 p.Research output: Contribution to conference › Paper › Research › peer-review
- Published
Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., Bochud, M. & 31 others, , 14 Apr 2013, In: Nature Genetics. 45, 6, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis
Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immature truncated O-glycophenotype of cancer directly induces oncogenic features
Radhakrishnan, P., Dabelsteen, S., Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, C., Vakhrushev, S. Y., Olsen, J. V., Hansen, L., Bennett, E. P., Woetmann, A., Yin, G., Chen, L., Song, H., Bak, M., Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, K. & 4 others, , 12 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis of Tousled-Like Kinase 2 activation
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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