Saskia Hoffmann
Associate Professor
- Published
Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability
Achuthankutty, D., Thakur, R. S., Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, A. H., Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.Research output: Contribution to journal › Journal article › Research › peer-review
p53 and cell cycle dependent transcription of kinesin family member 23 (KIF23) is controlled via a CHR promoter element bound by DREAM and MMB complexes
Fischer, M., Grundke, I., Sohr, S., Quaas, M., Hoffmann, Saskia, Knörck, A., Gumhold, C. & Rother, K., 2013, In: PLoS ONE. 8, 5, p. e63187Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the ATR kinase by the RPA-binding protein ETAA1
Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability
Haahr, Peter Thorlund, Borgermann, N., Guo, X., Typas, D., Achuthankutty, D., Hoffmann, Saskia, Shearer, Robert Francis, Sixma, T. K. & Mailand, Niels, 2018, In: Molecular Cell. 70, 1, p. 165-174Research output: Contribution to journal › Journal article › Research › peer-review
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TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease
Hoffmann, Saskia, Pentakota, S., Mund, Andreas, Haahr, Peter Thorlund, Coscia, F., Gallo, M., Mann, Matthias, Taylor, Nicholas M I & Mailand, Niels, 2020, In: EMBO Reports. 21, 10, 14 p., e50662.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control
Klein, D. K., Hoffmann, Saskia, Ahlskog, J. K., O'Hanlon, K., Quaas, M., Larsen, Brian Daniel, Rolland, B., Rösner, Heike Ilona, Walter, D., Kousholt, A. N., Menzel, T., Lees, M., Johansen, Jens Vilstrup, Rappsilber, J., Engeland, K. & Sørensen, Claus Storgaard, 2015, In: Nature Communications. 6, p. 5800Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RADX interacts with single-stranded DNA to promote replication fork stability
Schubert, Lisa, Ho, T., Hoffmann, Saskia, Haahr, Peter Thorlund, Guérillon, C. & Mailand, Niels, Nov 2017, In: EMBO Reports. 18, 11, p. 1991-2003 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway
Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.Research output: Contribution to journal › Journal article › Research › peer-review
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TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication
Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication
Walter, D., Hoffmann, Saskia, Komseli, E., Rappsilber, J., Gorgoulis, V. & Sørensen, Claus Storgaard, 2016, In: Nature Communications. 7, 10 p., 10530.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 40814530
Most downloads
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2006
downloads
Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
898
downloads
Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage
Research output: Contribution to journal › Letter › Research › peer-review
Published -
464
downloads
TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Research output: Contribution to journal › Journal article › Research › peer-review
Published