Saskia Hoffmann

Saskia Hoffmann

Associate Professor


  1. 2021
  2. Published

    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

    Gallina, Irene, Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, L., Sellés Baiget, Selene, Fábián, Zita, Kühbacher, Ulrike, Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2020
  4. Published

    FAM111 protease activity undermines cellular fitness and is amplified by gain-of-function mutations in human disease

    Hoffmann, Saskia, Pentakota, Satya Krishna, Mund, Andreas, Haahr, Peter Thorlund, Coscia, F., Gallo, M., Mann, Matthias, Taylor, Nicholas M I & Mailand, Niels, 2020, In: EMBO Reports. 21, 10, 14 p., e50662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2019
  6. Published

    Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability

    Achuthankutty, D., Thakur, R. S., Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, Anna Helene, Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

    Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2018
  9. Published

    ZUFSP Deubiquitylates K63-Linked Polyubiquitin Chains to Promote Genome Stability

    Haahr, Peter Thorlund, Borgermann, N., Guo, X., Typas, Dimitris, Achuthankutty, D., Hoffmann, Saskia, Shearer, R., Sixma, T. K. & Mailand, Niels, 2018, In: Molecular Cell. 70, 1, p. 165-174

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2017
  11. Published

    RADX interacts with single-stranded DNA to promote replication fork stability

    Schubert, L., Ho, T., Hoffmann, Saskia, Haahr, Peter Thorlund, Guérillon, C. & Mailand, Niels, Nov 2017, In: EMBO Reports. 18, 11, p. 1991-2003 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2016
  13. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, Luis Ignacio, Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

    Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication

    Walter, D., Hoffmann, Saskia, Komseli, E., Rappsilber, J., Gorgoulis, V. & Sørensen, Claus Storgaard, 2016, In: Nature Communications. 7, 10 p., 10530.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2015
  17. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

Previous 1 2 Next

ID: 40814530