Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. 2018
  2. Published

    Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future

    Comes, A. L., Papiol, S., Mueller, T., Geyer, P. E., Mann, Matthias & Schulze, T. G., 1 Dec 2018, In: Translational Psychiatry. 8, p. 1-15 15 p., 160.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    The proteome of prostate cancer bone metastasis reveals heterogeneity with prognostic implications

    Iglesias Gato, Diego, Thysell, E., Tyanova, S., Crnalic, S., Santos, A., Lima, T. S., Geiger, T., Cox, J., Widmark, A., Bergh, A., Mann, Matthias, Flores-Morales, A. & Wikström, P., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5433-5444 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex

    Link, S., Spitzer, R. M. M., Sana, M., Torrado, M., Völker-Albert, M. C., Keilhauer, E. C., Burgold, T., Pünzeler, S., Low, J. K. K., Lindström, I., Nist, A., Regnard, C., Stiewe, T., Hendrich, B., Imhof, A., Mann, Matthias, Mackay, J. P., Bartkuhn, M. & Hake, S. B., 16 Oct 2018, In: Nature Communications. 9, 1, p. 4300

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. UBL3 modification influences protein sorting to small extracellular vesicles

    Ageta, H., Ageta-Ishihara, N., Hitachi, K., Karayel, O., Onouchi, T., Yamaguchi, H., Kahyo, T., Hatanaka, K., Ikegami, K., Yoshioka, Y., Nakamura, K., Kosaka, N., Nakatani, M., Uezumi, A., Ide, T., Tsutsumi, Y., Sugimura, H., Kinoshita, M., Ochiya, T., Mann, M. & 2 others, Setou, M. & Tsuchida, K., 26 Sep 2018, In: Nature Communications. 9, 1, p. 3936

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion

    Liu, J. J., Chiu, Y., DiMattio, K. M., Chen, C., Huang, P., Gentile, T. A., Muschamp, J. W., Cowan, A., Mann, Matthias & Liu-Chen, L., 20 Jul 2018, (E-pub ahead of print) In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

    Wierer, M., Prestel, M., Schiller, H., Yan, G., Schaab, C., Azghandi, S., Werner, J., Kessler, T., Malik, R., Murgia, M., Aherrahrou, Z., Schunkert, H., Dichgans, M. & Mann, Matthias, Feb 2018, In: Molecular and Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase

    Lis, P., Burel, S., Steger, M., Mann, Matthias, Brown, F., Diez, F., Tonelli, F., Holton, J. L., Ho, P. W., Ho, S., Chou, M., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., Jan 2018, In: Biochemical Journal. 475, 1, 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

    Chheda, Z. S., Kohanbash, G., Okada, K., Jahan, N., Sidney, J., Pecoraro, M., Yang, X., Carrera, D. A., Downey, K. M., Shrivastav, S., Liu, S., Lin, Y., Lagisetti, C., Chuntova, P., Watchmaker, P. B., Mueller, S., Pollack, I. F., Rajalingam, R., Carcaboso, A. M., Mann, M. & 4 others, Sette, A., Garcia, K. C., Hou, Y. & Okada, H., Jan 2018, In: The Journal of Experimental Medicine. 215, 1, p. 141-157 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization

    Korge, S., Maier, B., Brüning, F., Ehrhardt, L., Korte, T., Mann, Matthias, Herrmann, A., Robles, M. S. & Kramer, A., Jan 2018, In: P L o S Genetics. 14, 1, p. e1007189

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics

    Bache, N., Geyer, P. E., Bekker-Jensen, D. B., Hørning, O., Falkenby, L., Treit, P. V., Doll, S., Paron, I., Müller, J. B., Meier, F., Olsen, Jesper Velgaard, Vorm, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 11, p. 2284-2296 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes

    Meier, F., Geyer, P. E., Virreira Winter, S., Cox, J. & Mann, Matthias, 2018, In: Nature Methods. 15, 6, p. 440-448 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Constructing a cell-type resolved human liver proteome atlas: THU-034

    Niu, Lili, Geyer, P. & Mann, Matthias, 2018, In: Journal of Hepatology. 68, p. S138-S139

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification

    Virreira Winter, S., Meier, F., Wichmann, C., Cox, J., Mann, Matthias & Meissner, F., 2018, In: Nature Methods. 15, 7, p. 527-530 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform

    Humphrey, S. J., Karayel, O., James, D. E. & Mann, Matthias, 2018, In: Nature Protocols (Print). 13, p. 1897-1916 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    In vivo brain GPCR signaling elucidated by phosphoproteomics

    Liu, J. J., Sharma, K., Zangrandi, L., Chen, C., Humphrey, S. J., Chiu, Y., Spetea, M., Liu-Chen, L., Schwarzer, C. & Mann, Matthias, 2018, In: Science (New York, N.Y.). 360, 6395, p. 1-11

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. In-depth proteomic analyses of (greenlip abalone) nacre and prismatic organic shell matrix

    Mann, K., Cerveau, N., Gummich, M., Fritz, M., Mann, Matthias & Jackson, D. J., 2018, In: Proteome Science. 16, p. 11

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

    Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.

    Research output: Working paperPreprintResearch

  19. Molecular and structural architecture of polyQ aggregates in yeast

    Gruber, A., Hornburg, D., Antonin, M., Krahmer, N., Collado, J., Schaffer, M., Zubaite, G., Lüchtenborg, C., Sachsenheimer, T., Brügger, B., Mann, Matthias, Baumeister, W., Hartl, F. U., Hipp, M. S. & Fernández-Busnadiego, R., 2018, In: Proceedings of the National Academy of Sciences of the United States of America.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

    Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, Jakob, Mund, Andreas, Mann, Matthias & Curtis, M., 2018, In: Cell. 175, 1, p. 159-170.e16

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

    Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 12, p. 2534-2545

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Opinion: Advocating for science progress as a human right

    Porsdam Mann, Sebastian, Donders, Y., Mitchell, C., Bradley, V. J., Chou, M. F., Mann, Matthias, Church, G. & Porsdam, Helle, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10820-10823 4 p.

    Research output: Contribution to journalComment/debateCommunication

  23. Published

    Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis

    Krahmer, N., Najafi, B., Schueder, F., Quagliarini, F., Steger, M., Seitz, S., Kasper, R., Salinas, F., Cox, J., Uhlenhaut, N. H., Walther, T. C., Jungmann, R., Zeigerer, A., Borner, G. H. H. & Mann, Matthias, 2018, In: Developmental Cell. 47, 2, p. 205-221.E7

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

    Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Proteomics in the Study of Liver Diseases

    Niu, Lili, Geyer, P. E. & Mann, Matthias, 2018, The Human Gut-Liver-Axis in Health and Disease. Krag, A. & Hansen, T. (eds.). Springer, p. 165-193

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  26. Published

    Quality control for plasma and cerebrospinal fluid samples using mass spectrometry

    Skotte, N. H., Geyer, P. E., Steger, M., Treit, P. V., Voytik, E., Hellem, M. N., Nielsen, Jørgen Erik & Mann, Matthias, 2018, In: Journal of Neurology, Neurosurgery and Psychiatry. 89, p. A31-A32

    Research output: Contribution to journalConference abstract in journalResearch

  27. Published

    Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient

    Doll, S., Kriegmair, M. C., Santos, A., Wierer, M., Coscia, F., Neil, H. M., Porubsky, S., Geyer, P. E., Mund, Andreas, Nuhn, P. & Mann, Matthias, 2018, In: Molecular Oncology. 12, 8, p. 1296-1307 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. The Transcription Factor ETV1 Induces Atrial Remodeling and Arrhythmia

    Rommel, C., Rösner, S., Lother, A., Barg, M., Schwaderer, M., Gilsbach, R., Bömicke, T., Schnick, T., Mayer, S., Doll, S., Hesse, M., Kretz, O., Stiller, B., Neumann, F., Mann, Matthias, Krane, M., Fleischmann, B. K., Ravens, U. & Hein, L., 2018, In: Circulation Research. 123, 5, p. 550-563 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. The hemicellulose-degrading enzyme system of the thermophilic bacterium Clostridium stercorarium: comparative characterisation and addition of new hemicellulolytic glycoside hydrolases

    Broeker, J., Mechelke, M., Baudrexl, M., Mennerich, D., Hornburg, D., Mann, Matthias, Schwarz, W. H., Liebl, W. & Zverlov, V. V., 2018, In: Biotechnology for Biofuels. 11, p. 229

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 5650809