Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

    Publication year:
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    151 - 200 out of 358Page size: 50
    1. 2019
    2. Published

      Development, use, application of novel TIMS-Tof system

      Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S20 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    3. Published

      Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

      Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

      Seitz, S., Kwon, Y., Hartleben, G., Juelg, J., Sekar, R., Krahmer, N., Najafi, B., Loft, A., Gancheva, S., Stemmer, K., Feuchtinger, A., de Angelis, M. H., Mueller, T. D., Mann, M., Blueher, M., Roden, M., Diaz, M. B., Behrends, C., Gilleron, J., Herzig, S. & 1 others, Zeigerer, A., 2019, In: Nature Metabolism. 1, p. 1009-1026

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      MaxQuant.Live enables global targeting of more than 25,000 peptides

      Wichmann, C., Meier, F., Virreira Winter, S., Brunner, A., Cox, J. & Mann, Matthias, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 982-994 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

      Hart, P. C., Kenny, H. A., Grassl, N., Watters, K. M., Litchfield, L. M., Coscia, F., Blaženović, I., Ploetzky, L., Fiehn, O., Mann, Matthias, Lengyel, E. & Romero, I. L., 2019, In: Cell Reports. 29, 12, p. 4086-4098.e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Metallopeptidase Inhibitor 1 (TIMP-1) promotes receptor tyrosine kinase c-Kit signaling in colorectal cancer

      Nordgaard, C., Doll, S., Matos, A. L. D. S. A., Høeberg, M., Kazi, J. U., Friis, S., Stenvang, Jan, Rönnstrand, L., Mann, Matthias & Moreira, José, 2019, In: Molecular Oncology. 13, 12, p. 2646-2662

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Mobi-DIK (Ion Mobility DIA Analysis Kit): Targeted analysis software for diaPASEF data improves proteome coverage

      Ha, A., Frank, M., Meier, F., Brunner, A., Kaspar-Schoenefeld, S., Koch, S., Lubeck, M., Raether, O., Collins, B. C., Aebersold, R., Mann, Matthias & Rost, H., 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    9. Published

      Myosin binding protein H-like (MYBPHL): a promising biomarker to predict atrial damage

      Lahm, H., Dressen, M., Beck, N., Doppler, S., Deutsch, M., Matsushima, S., Neb, I., Koenig, K. C., Sideris, K., Voss, S., Eschenbach, L., Puluca, N., Deisenhofer, I., Doll, S., Holdenrieder, S., Mann, Matthias, Lange, R. & Krane, M., 2019, In: Scientific Reports. 9, 8 p., 9986.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Neurodevelopmental deficits in human isogenic fragile x syndrome neurons

      Utami, K., Skotte, N. H., Colaco, A. R. -., Yusof, N. A. B. M., Sim, B., Yeo, X. Y., Bae, H., Garcia-Miralles, M., Radulescu, C., Jung, S., Mann, Matthias & Pouladi, M., 2019, In: Journal of Neurochemistry. 150, p. 103 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    11. Published

      Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)

      Meier, F., Brunner, A., Frank, M., Ha, A., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    12. Published

      Plasma Proteome Profiling to detect and avoid sample-related biases in biomarker studies

      Geyer, P. E., Voytik, E., Treit, P. V., Doll, S., Kleinhempel, A., Niu, Lili, Müller, J. B., Buchholtz, M., Bader, J. M., Teupser, D., Holdt, L. M. & Mann, Matthias, 2019, In: EMBO Molecular Medicine. 11, 11, e10427.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

      Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy

      Murgia, M., Tan, J., Geyer, P. E., Doll, S., Mann, Matthias & Klopstock, T., 2019, In: Cell Reports. 29, 12, p. 3825-3834 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

      Eckert, M. A., Coscia, F., Chryplewicz, A., Chang, J. W., Hernandez, K. M., Pan, S., Tienda, S. M., Nahotko, D. A., Li, G., Blaženović, I., Lastra, R. R., Curtis, M., Yamada, S. D., Perets, R., McGregor, S. M., Andrade, J., Fiehn, O., Moellering, R. E., Mann, Matthias & Lengyel, E., 2019, In: Nature. 569, 7758, p. 723-728

      Research output: Contribution to journal › Letter › Research › peer-review

    16. Published

      Proteomics-Based Comparative Mapping of the Secretomes of Human Brown and White Adipocytes Reveals EPDR1 as a Novel Batokine

      Deshmukh, A. S., Peijs, L., Beaudry, J. L., Jespersen, N. Z., Nielsen, C. H., Ma, T., Brunner, A. D., Larsen, T. J., Bayarri-Olmos, R., Prabhakar, B. S., Helgstrand, C., Severinsen, M. C. K., Holst, B., Kjaer, A., Tang-Christensen, M., Sanfridson, A., Garred, P., Privé, G. G., Pedersen, B. K., Gerhart-Hines, Z. & 4 others, Nielsen, S., Drucker, D. J., Mann, Matthias & Schéele, Camilla Charlotte Nielsen, 2019, In: Cell Metabolism. 30, 5, p. 963-975.e7 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Quick and clean: Cracking sentences encoded in E. coli by LC-MS/MS, de novo sequencing, and dictionary search

      Niu, Lili & Mann, Matthias, 2019, In: EuPA Open Proteomics. 22-23, p. 30-35 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

      Larsen, N. B., Gao, A. O., Sparks, J. L., Gallina, I., Wu, R. A., Mann, Matthias, Räschle, M., Walter, J. C. & Duxin, Julien, 2019, In: Molecular Cell. 73, 3, p. 574-588.e7 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Response to Raaijmakers & Medema

      Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.

      Research output: Contribution to journal › Comment/debate › Research

    20. Published

      SILAC-based quantitative mass spectrometry-based proteomics quantifies endoplasmic reticulum stress in whole HeLa cells

      Itzhak, D. N., Sacco, F., Nagaraj, N., Tyanova, S., Mann, Matthias & Murgia, M., 2019, In: Disease Models & Mechanisms. 12, 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Sleep-wake cycles drive daily dynamics of synaptic phosphorylation

      Brüning, F., Noya, S. B., Bange, T., Koutsouli, S., Rudolph, J. D., Tyagarajan, S. K., Cox, J., Mann, Matthias, Brown, S. A. & Robles, M. S., 2019, In: Science (New York, N.Y.). 366, 6462, eaav3617 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

      Sparks, J. L., Chistol, G., Gao, A. O., Räschle, M., Larsen, N. B., Mann, Matthias, Duxin, Julien & Walter, J. C., 2019, In: Cell. 176, 1-2, p. 167-181.e21

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      The Case for Proteomics and Phospho-Proteomics in Personalized Cancer Medicine

      Doll, S., Gnad, F. & Mann, Matthias, 2019, In: Proteomics - Clinical Applications. 13, 2, 10 p., e1800113.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      The ever expanding scope of electrospray mass spectrometry-a 30 year journey

      Mann, Matthias, 2019, In: Nature Communications. 10, 3744.

      Research output: Contribution to journal › Comment/debate › Research

    25. Published

      The forebrain synaptic transcriptome is organized by clocks but its proteome is driven by sleep

      Noya, S. B., Colameo, D., Brüning, F., Spinnler, A., Mircsof, D., Opitz, L., Mann, Matthias, Tyagarajan, S. K., Robles, M. S. & Brown, S. A., 2019, In: Science. 366, 6462, eaav2642 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. 2018
    27. Published

      Proteomics for blood biomarker exploration of severe mental illness: pitfalls of the past and potential for the future

      Comes, A. L., Papiol, S., Mueller, T., Geyer, P. E., Mann, Matthias & Schulze, T. G., 1 Dec 2018, In: Translational Psychiatry. 8, p. 1-15 15 p., 160.

      Research output: Contribution to journal › Review › Research › peer-review

    28. Published

      The proteome of prostate cancer bone metastasis reveals heterogeneity with prognostic implications

      Iglesias Gato, Diego, Thysell, E., Tyanova, S., Crnalic, S., Santos, A., Lima, T. S., Geiger, T., Cox, J., Widmark, A., Bergh, A., Mann, Matthias, Flores-Morales, A. & Wikström, P., 1 Nov 2018, In: Clinical Cancer Research. 24, 21, p. 5433-5444 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex

      Link, S., Spitzer, R. M. M., Sana, M., Torrado, M., Völker-Albert, M. C., Keilhauer, E. C., Burgold, T., Pünzeler, S., Low, J. K. K., Lindström, I., Nist, A., Regnard, C., Stiewe, T., Hendrich, B., Imhof, A., Mann, Matthias, Mackay, J. P., Bartkuhn, M. & Hake, S. B., 16 Oct 2018, In: Nature Communications. 9, 1, p. 4300

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. UBL3 modification influences protein sorting to small extracellular vesicles

      Ageta, H., Ageta-Ishihara, N., Hitachi, K., Karayel, O., Onouchi, T., Yamaguchi, H., Kahyo, T., Hatanaka, K., Ikegami, K., Yoshioka, Y., Nakamura, K., Kosaka, N., Nakatani, M., Uezumi, A., Ide, T., Tsutsumi, Y., Sugimura, H., Kinoshita, M., Ochiya, T., Mann, M. & 2 others, Setou, M. & Tsuchida, K., 26 Sep 2018, In: Nature Communications. 9, 1, p. 3936

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Phosphoproteomic approach for agonist-specific signaling in mouse brains: mTOR pathway is involved in κ opioid aversion

      Liu, J. J., Chiu, Y., DiMattio, K. M., Chen, C., Huang, P., Gentile, T. A., Muschamp, J. W., Cowan, A., Mann, Matthias & Liu-Chen, L., 20 Jul 2018, (E-pub ahead of print) In: Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

      Wierer, M., Prestel, M., Schiller, H., Yan, G., Schaab, C., Azghandi, S., Werner, J., Kessler, T., Malik, R., Murgia, M., Aherrahrou, Z., Schunkert, H., Dichgans, M. & Mann, Matthias, Feb 2018, In: Molecular and Cellular Proteomics.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase

      Lis, P., Burel, S., Steger, M., Mann, Matthias, Brown, F., Diez, F., Tonelli, F., Holton, J. L., Ho, P. W., Ho, S., Chou, M., Polinski, N. K., Martinez, T. N., Davies, P. & Alessi, D. R., Jan 2018, In: Biochemical Journal. 475, 1, 22 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Novel and shared neoantigen derived from histone 3 variant H3.3K27M mutation for glioma T cell therapy

      Chheda, Z. S., Kohanbash, G., Okada, K., Jahan, N., Sidney, J., Pecoraro, M., Yang, X., Carrera, D. A., Downey, K. M., Shrivastav, S., Liu, S., Lin, Y., Lagisetti, C., Chuntova, P., Watchmaker, P. B., Mueller, S., Pollack, I. F., Rajalingam, R., Carcaboso, A. M., Mann, M. & 4 others, Sette, A., Garcia, K. C., Hou, Y. & Okada, H., Jan 2018, In: The Journal of Experimental Medicine. 215, 1, p. 141-157 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. The non-classical nuclear import carrier Transportin 1 modulates circadian rhythms through its effect on PER1 nuclear localization

      Korge, S., Maier, B., Brüning, F., Ehrhardt, L., Korte, T., Mann, Matthias, Herrmann, A., Robles, M. S. & Kramer, A., Jan 2018, In: P L o S Genetics. 14, 1, p. e1007189

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      A novel LC system embeds analytes in pre-formed gradients for rapid, ultra-robust proteomics

      Bache, N., Geyer, P. E., Bekker-Jensen, D. B., Hørning, O., Falkenby, L., Treit, P. V., Doll, S., Paron, I., Müller, J. B., Meier, F., Olsen, Jesper Velgaard, Vorm, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 11, p. 2284-2296 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes

      Meier, F., Geyer, P. E., Virreira Winter, S., Cox, J. & Mann, Matthias, 2018, In: Nature Methods. 15, 6, p. 440-448 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Constructing a cell-type resolved human liver proteome atlas: THU-034

      Niu, Lili, Geyer, P. & Mann, Matthias, 2018, In: Journal of Hepatology. 68, p. S138-S139

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    39. Published

      EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification

      Virreira Winter, S., Meier, F., Wichmann, C., Cox, J., Mann, Matthias & Meissner, F., 2018, In: Nature Methods. 15, 7, p. 527-530 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      High-throughput and high-sensitivity phosphoproteomics with the EasyPhos platform

      Humphrey, S. J., Karayel, O., James, D. E. & Mann, Matthias, 2018, In: Nature Protocols (Print). 13, p. 1897-1916 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Published

      In vivo brain GPCR signaling elucidated by phosphoproteomics

      Liu, J. J., Sharma, K., Zangrandi, L., Chen, C., Humphrey, S. J., Chiu, Y., Spetea, M., Liu-Chen, L., Schwarzer, C. & Mann, Matthias, 2018, In: Science (New York, N.Y.). 360, 6395, p. 1-11

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. In-depth proteomic analyses of (greenlip abalone) nacre and prismatic organic shell matrix

      Mann, K., Cerveau, N., Gummich, M., Fritz, M., Mann, Matthias & Jackson, D. J., 2018, In: Proteome Science. 16, p. 11

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

      Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.

      Research output: Working paper › Preprint › Research

    44. Molecular and structural architecture of polyQ aggregates in yeast

      Gruber, A., Hornburg, D., Antonin, M., Krahmer, N., Collado, J., Schaffer, M., Zubaite, G., Lüchtenborg, C., Sachsenheimer, T., Brügger, B., Mann, Matthias, Baumeister, W., Hartl, F. U., Hipp, M. S. & Fernández-Busnadiego, R., 2018, In: Proceedings of the National Academy of Sciences of the United States of America.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

      Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, Jakob, Mund, Andreas, Mann, Matthias & Curtis, M., 2018, In: Cell. 175, 1, p. 159-170.e16

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer

      Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 12, p. 2534-2545

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Opinion: Advocating for science progress as a human right

      Porsdam Mann, Sebastian, Donders, Y., Mitchell, C., Bradley, V. J., Chou, M. F., Mann, Matthias, Church, G. & Porsdam, Helle, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10820-10823 4 p.

      Research output: Contribution to journal › Comment/debate › Communication

    48. Published

      Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis

      Krahmer, N., Najafi, B., Schueder, F., Quagliarini, F., Steger, M., Seitz, S., Kasper, R., Salinas, F., Cox, J., Uhlenhaut, N. H., Walther, T. C., Jungmann, R., Zeigerer, A., Borner, G. H. H. & Mann, Matthias, 2018, In: Developmental Cell. 47, 2, p. 205-221.E7

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

      Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Proteomics in the Study of Liver Diseases

      Niu, Lili, Geyer, P. E. & Mann, Matthias, 2018, The Human Gut-Liver-Axis in Health and Disease. Krag, A. & Hansen, T. (eds.). Springer, p. 165-193

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    51. Published

      Quality control for plasma and cerebrospinal fluid samples using mass spectrometry

      Skotte, N. H., Geyer, P. E., Steger, M., Treit, P. V., Voytik, E., Hellem, M. N., Nielsen, Jørgen Erik & Mann, Matthias, 2018, In: Journal of Neurology, Neurosurgery and Psychiatry. 89, p. A31-A32

      Research output: Contribution to journal › Conference abstract in journal › Research

    52. Published

      Rapid proteomic analysis for solid tumors reveals LSD1 as a drug target in an end-stage cancer patient

      Doll, S., Kriegmair, M. C., Santos, A., Wierer, M., Coscia, F., Neil, H. M., Porubsky, S., Geyer, P. E., Mund, Andreas, Nuhn, P. & Mann, Matthias, 2018, In: Molecular Oncology. 12, 8, p. 1296-1307 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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