Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

    Publication year:
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    201 - 300 out of 359Page size: 100
    1. 2018
    2. Published

      EASI-tag enables accurate multiplexed and interference-free MS2-based proteome quantification

      Virreira Winter, S., Meier, F., Wichmann, C., Cox, J., Mann, Matthias & Meissner, F., 2018, In: Nature Methods. 15, 7, p. 527-530 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

      Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Compartment-resolved Proteomic Analysis of Mouse Aorta during Atherosclerotic Plaque Formation Reveals Osteoclast-specific Protein Expression

      Wierer, M., Prestel, M., Schiller, H., Yan, G., Schaab, C., Azghandi, S., Werner, J., Kessler, T., Malik, R., Murgia, M., Aherrahrou, Z., Schunkert, H., Dichgans, M. & Mann, Matthias, Feb 2018, In: Molecular and Cellular Proteomics.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. 2017
    6. Published

      Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

      Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination

      Dewar, J. M., Low, E., Mann, Matthias, Räschle, M. & Walter, J. C., 1 Feb 2017, In: Genes & Development. 31, 3, p. 275-290 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Region and cell-type resolved quantitative proteomic map of the human heart

      Doll, S., Dreßen, M., Geyer, P. E., Itzhak, D. N., Braun, C., Doppler, S. A., Meier, F., Deutsch, M., Lahm, H., Lange, R., Krane, M. & Mann, Matthias, 13 Nov 2017, In: Nature Communications. 8, 1, 13 p., 1469.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Revisiting biomarker discovery by plasma proteomics

      Geyer, P. E., Holdt, L. M., Teupser, D. & Mann, Matthias, 26 Sep 2017, In: Molecular Systems Biology. 13, 9, 16 p., 942.

      Research output: Contribution to journal › Review › Research › peer-review

    10. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis

      Hartl, M., Füßl, M., Boersema, P. J., Jost, J., Kramer, K., Bakirbas, A., Sindlinger, J., Plöchinger, M., Leister, D., Uhrig, G., Moorhead, G. B., Cox, J., Salvucci, M. E., Schwarzer, D., Mann, Matthias & Finkemeier, I., 2017, In: Molecular Systems Biology. 13, 10, 16 p., 949.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      A Primer on Concepts and Applications of Proteomics in Neuroscience

      Hosp, F. & Mann, Matthias, 1 Nov 2017, In: Neuron. 96, 3, p. 558-571 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    12. Lysine acetylation in mitochondria: From inventory to function

      Hosp, F., Lassowskat, I., Santoro, V., De Vleesschauwer, D., Fliegner, D., Redestig, H., Mann, Matthias, Christian, S., Hannah, M. A. & Finkemeier, I., Mar 2017, In: Mitochondrion. 33, p. 58-71 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function

      Hosp, F., Gutiérrez-Ángel, S., Schaefer, M. H., Cox, J., Meissner, F., Hipp, M. S., Hartl, F., Klein, R., Dudanova, I. & Mann, Matthias, 21 Nov 2017, In: Cell Reports. 21, 8, p. 2291-2303 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Phylointeractomics reconstructs functional evolution of protein binding

      Kappei, D., Scheibe, M., Paszkowski-Rogacz, M., Bluhm, A., Gossmann, T. I., Dietz, S., Dejung, M., Herlyn, H., Buchholz, F., Mann, Matthias & Butter, F., 8 Feb 2017, In: Nature Communications. 8, p. 14334

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

      Kulak, N. A., Geyer, P. E. & Mann, Matthias, Apr 2017, In: Molecular and Cellular Proteomics. 16, 4, p. 694-705 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

      Kälin, S., Becker, M., Ott, V. B., Serr, I., Hosp, F., Mollah, M. M. H., Keipert, S., Lamp, D., Rohner-Jeanrenaud, F., Flynn, V. K., Scherm, M. G., Nascimento, L. F. R., Gerlach, K., Popp, V., Dietzen, S., Bopp, T., Krishnamurthy, P., Kaplan, M. H., Serrano, M., Woods, S. C. & 10 others, Tripal, P., Palmisano, R., Jastroch, M., Blüher, M., Wolfrum, C., Weigmann, B., Ziegler, A., Mann, Matthias, Tschöp, M. H. & Daniel, C., 5 Sep 2017, In: Cell Metabolism. 26, 3, p. 475-492.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Plenary Lecture Proteomics technologies for signaling, clinical applications

      Mann, Matthias, 2017, p. S62. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    18. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging

      Murgia, M., Toniolo, L., Nagaraj, N., Ciciliot, S., Vindigni, V., Schiaffino, S., Reggiani, C. & Mann, Matthias, 13 Jun 2017, In: Cell Reports. 19, 11, p. 2396-2409 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation

      Pünzeler, S., Link, S., Wagner, G., Keilhauer, E. C., Kronbeck, N., Spitzer, R. M., Leidescher, S., Markaki, Y., Mentele, E., Regnard, C., Schneider, K., Takahashi, D., Kusakabe, M., Vardabasso, C., Zink, L. M., Straub, T., Bernstein, E., Harata, M., Leonhardt, H., Mann, M. & 2 others, Rupp, R. A. & Hake, S. B., 1 Aug 2017, In: E M B O Journal. 36, 15, p. 2263-2279 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Social network architecture of human immune cells unveiled by quantitative proteomics

      Rieckmann, J. C., Geiger, R., Hornburg, D., Wolf, T., Kveler, K., Jarrossay, D., Sallusto, F., Shen-Orr, S. S., Lanzavecchia, A., Mann, Matthias & Meissner, F., May 2017, In: Nature Immunology. 18, 5, p. 583-593 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology

      Robles, M. S., Humphrey, S. J. & Mann, Matthias, 10 Jan 2017, In: Cell Metabolism. 25, 1, p. 118-127 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Deep Proteome Profiling Reveals Common Prevalence of MZB1-positive Plasma B Cells in Human Lung and Skin Fibrosis

      Schiller, H. B., Mayr, C. H., Leuschner, G., Strunz, M., Staab-Weijnitz, C., Preisendörfer, S., Eckes, B., Moinzadeh, P., Krieg, T., Schwartz, D. A., Hatz, R. A., Behr, J., Mann, Matthias & Eickelberg, O., 2017, In: American Journal of Respiratory and Critical Care Medicine. 196, 10, p. 1298–1310

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Systematic proteomic analysis of LRRK2-mediated Rab GTPase phosphorylation establishes a connection to ciliogenesis

      Steger, M., Diez, F., Dhekne, H. S., Lis, P., Nirujogi, R. S., Karayel, O., Tonelli, F., Martinez, T. N., Lorentzen, E., Pfeffer, S. R., Alessi, D. R. & Mann, Matthias, 10 Nov 2017, In: eLife. 6

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. A proteomic atlas of insulin signalling reveals tissue-specific mechanisms of longevity assurance

      Tain, L. S., Sehlke, R., Jain, C., Chokkalingam, M., Nagaraj, N., Essers, P., Rassner, M., Grönke, S., Froelich, J., Dieterich, C., Mann, Matthias, Alic, N., Beyer, A. & Partridge, L., 15 Sep 2017, In: Molecular Systems Biology. 13, 9, p. 939

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Widespread Proteome Remodeling and Aggregation in Aging C. elegans

      Walther, D. M., Kasturi, P., Zheng, M., Pinkert, S., Vecchi, G., Ciryam, P., Morimoto, R. I., Dobson, C. M., Vendruscolo, M., Mann, Matthias & Hartl, F. U., 23 Feb 2017, In: Cell. 168, 5, p. 944

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Why is it so difficult to measure glucagon-like peptide-1 in a mouse?

      Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. H3.Y discriminates between HIRA and DAXX chaperone complexes and reveals unexpected insights into human DAXX-H3.3-H4 binding and deposition requirements

      Zink, L., Delbarre, E., Eberl, H. C., Keilhauer, E. C., Bönisch, C., Pünzeler, S., Bartkuhn, M., Collas, P., Mann, Matthias & Hake, S. B., 2 Jun 2017, In: Nucleic Acids Research. 45, 10, p. 5691-5706 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. 2016
    29. Published

      Mass-spectrometric exploration of proteome structure and function

      Aebersold, R. & Mann, Matthias, 15 Sep 2016, In: Nature. 537, 7620, p. 347-55 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

      Bassani-Sternberg, M., Bräunlein, E., Klar, R., Engleitner, T., Sinitcyn, P., Audehm, S., Straub, M., Weber, J., Slotta-Huspenina, J., Specht, K., Martignoni, M. E., Werner, A., Hein, R., H Busch, D., Peschel, C., Rad, R., Cox, J., Mann, Matthias & Krackhardt, A. M., 21 Nov 2016, In: Nature Communications. 7, p. 13404

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

      Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC

      Frey, F., Sheahan, T., Finkl, K., Stoehr, G., Mann, Matthias, Benda, C. & Müller, J., 1 May 2016, In: Genes & Development. 30, 9, p. 1116-27 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

      Geiger, R., Rieckmann, J. C., Wolf, T., Basso, C., Feng, Y., Fuhrer, T., Kogadeeva, M., Picotti, P., Meissner, F., Mann, Matthias, Zamboni, N., Sallusto, F. & Lanzavecchia, A., 20 Oct 2016, In: Cell. 167, 3, p. 829-842.e13

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Plasma Proteome Profiling to Assess Human Health and Disease

      Geyer, P. E., Kulak, N. A., Pichler, G., Holdt, L. M., Teupser, D. & Mann, Matthias, 23 Mar 2016, In: Cell Systems. 2, 3, p. 185-95 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Proteomics reveals the effects of sustained weight loss on the human plasma proteome

      Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

      Graham, B., Marcais, A., Dharmalingam, G., Carroll, T., Kanellopoulou, C., Graumann, J., Nesterova, T. B., Bermange, A., Brazauskas, P., Xella, B., Kriaucionis, S., Higgs, D. R., Brockdorff, N., Mann, Matthias, Fisher, A. G. & Merkenschlager, M., 10 May 2016, In: Stem Cell Reports. 6, 5, p. 635-642 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Ultra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome

      Grassl, N., Kulak, N. A., Pichler, G., Geyer, P. E., Jung, J., Schubert, S., Sinitcyn, P., Cox, J. & Mann, Matthias, 21 Apr 2016, In: Genome Medicine. 8, 13 p., 44.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins

      Guerrera, D., Shah, J., Vasileva, E., Sluysmans, S., Méan, I., Jond, L., Poser, I., Mann, Matthias, Hyman, A. A. & Citi, S., 20 May 2016, In: The Journal of Biological Chemistry. 291, 21, p. 11016-29 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Activation of the ATR kinase by the RPA-binding protein ETAA1

      Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

      Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

      Research output: Contribution to journal › Letter › Research › peer-review

    41. Published

      TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

      Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

      Holdt, L. M., Stahringer, A., Sass, K., Pichler, G., Kulak, N. A., Wilfert, W., Kohlmaier, A., Herbst, A., Northoff, B. H., Nicolaou, A., Gäbel, G., Beutner, F., Scholz, M., Thiery, J., Musunuru, K., Krohn, K., Mann, Matthias & Teupser, D., 19 Aug 2016, In: Nature Communications. 7, p. 12429

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      The Proteome of Primary Prostate Cancer

      Iglesias Gato, Diego, Wikström, P., Tyanova, S., Lavallee, C., Thysell, E., Carlsson, J., Hägglöf, C., Cox, J., Andrén, O., Stattin, P., Egevad, L., Widmark, A., Bjartell, A., Collins, C. C., Bergh, A., Geiger, T., Mann, Matthias & Flores-Morales, A., May 2016, In: European Urology. 69, 5, p. 942-952 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. HCD Fragmentation of Glycated Peptides

      Keilhauer, E. C., Geyer, P. E. & Mann, Matthias, 5 Aug 2016, In: Journal of Proteome Research. 15, 8, p. 2881-90 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors

      Kim, Y. E., Hosp, F., Frottin, F., Ge, H., Mann, Matthias, Hayer-Hartl, M. & Hartl, F. U., 15 Sep 2016, In: Molecular Cell. 63, 6, p. 951-64 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Erratum: Evidence of extrapancreatic glucagon secretion in man. Diabetes 2016;65:585-597

      Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jun 2016, In: Diabetes. 65, 6, p. 1752 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    47. Published

      Evidence of Extrapancreatic Glucagon Secretion in Man

      Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes. 65, 3, p. 585-597 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1

      Ma-Lauer, Y., Carbajo-Lozoya, J., Hein, M. Y., Müller, M. A., Deng, W., Lei, J., Meyer, B., Kusov, Y., von Brunn, B., Bairad, D. R., Hünten, S., Drosten, C., Hermeking, H., Leonhardt, H., Mann, Matthias, Hilgenfeld, R. & von Brunn, A., 30 Aug 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 35, p. E5192-201

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Origins of mass spectrometry-based proteomics

      Mann, Matthias, Nov 2016, In: Nature Reviews. Molecular Cell Biology. 17, 11, p. 678

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Inflammatory signaling in human tuberculosis granulomas is spatially organized

      Marakalala, M. J., Raju, R. M., Sharma, K., Zhang, Y. J., Eugenin, E. A., Prideaux, B., Daudelin, I. B., Chen, P., Booty, M. G., Kim, J. H., Eum, S. Y., Via, L. E., Behar, S. M., Barry, C. E., Mann, Matthias, Dartois, V. & Rubin, E. J., May 2016, In: Nature Medicine. 22, 5, p. 531-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data

      Mischnik, M., Sacco, F., Cox, J., Schneider, H., Schäfer, M., Hendlich, M., Crowther, D., Mann, Matthias & Klabunde, T., 1 Feb 2016, In: Bioinformatics (Online). 32, 3, p. 424-31 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

      Neufeld-Cohen, A., Robles, M. S., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., Mann, Matthias & Asher, G., 22 Mar 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 12, p. E1673-82

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State

      Sacco, F., Silvestri, A., Posca, D., Pirrò, S., Gherardini, P. F., Castagnoli, L., Mann, Matthias & Cesareni, G., 23 Mar 2016, In: Cell Systems. 2, 3, p. 159-71 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

      Sacco, F., Humphrey, S. J., Cox, J., Mischnik, M., Schulte, A., Klabunde, T., Schäfer, M. & Mann, Matthias, 14 Nov 2016, In: Nature Communications. 7, p. 13250

      Research output: Contribution to journal › Journal article › Research › peer-review

    55. A genome-wide resource for the analysis of protein localisation in Drosophila

      Sarov, M., Barz, C., Jambor, H., Hein, M. Y., Schmied, C., Suchold, D., Stender, B., Janosch, S., K J, V. V., Krishnan, R. T., Krishnamoorthy, A., Ferreira, I. R. S., Ejsmont, R. K., Finkl, K., Hasse, S., Kämpfer, P., Plewka, N., Vinis, E., Schloissnig, S., Knust, E. & 6 others, Hartenstein, V., Mann, Matthias, Ramaswami, M., VijayRaghavan, K., Tomancak, P. & Schnorrer, F., 20 Feb 2016, In: eLife. 5, p. e12068

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease

      Schamberger, A. C., Schiller, H. B., Fernandez, I. E., Sterclova, M., Heinzelmann, K., Hennen, E., Hatz, R., Behr, J., Vašáková, M., Mann, Matthias, Eickelberg, O. & Staab-Weijnitz, C. A., 20 Jul 2016, In: Scientific Reports. 6, p. 29952

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons

      Sivadasan, R., Hornburg, D., Drepper, C., Frank, N., Jablonka, S., Hansel, A., Lojewski, X., Sterneckert, J., Hermann, A., Shaw, P. J., Ince, P. G., Mann, Matthias, Meissner, F. & Sendtner, M., Dec 2016, In: Nature Neuroscience. 19, 12, p. 1610-1618 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    58. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

      Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. & Mann, Matthias, 29 Jan 2016, In: eLife. 5

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Homology-driven assembly of NOn-redundant protEin sequence sets (NOmESS) for mass spectrometry

      Temu, T., Mann, Matthias, Räschle, M. & Cox, J., 1 May 2016, In: Bioinformatics (Online). 32, 9, p. 1417-9 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Proteomic maps of breast cancer subtypes

      Tyanova, S., Albrechtsen, Reidar, Kronqvist, P., Cox, J., Mann, Matthias & Geiger, T., 4 Jan 2016, In: Nature Communications. 7, 11 p., 10259.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. The Perseus computational platform for comprehensive analysis of (prote)omics data

      Tyanova, S., Temu, T., Sinitcyn, P., Carlson, A., Hein, M. Y., Geiger, T., Mann, Matthias & Cox, J., Sep 2016, In: Nature Methods. 13, 9, p. 731-40 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    62. Published

      Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

      Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    63. Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes

      Wierer, M. & Mann, Matthias, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R106-R114

      Research output: Contribution to journal › Journal article › Research › peer-review

    64. A Proteomics Approach to the Protein Normalization Problem: Selection of Unvarying Proteins for MS-Based Proteomics and Western Blotting

      Wiśniewski, J. R. & Mann, Matthias, 1 Jul 2016, In: Journal of Proteome Research. 15, 7, p. 2321-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    65. Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

      Woerner, A. C., Frottin, F., Hornburg, D., Feng, L. R., Meissner, F., Patra, M., Tatzelt, J., Mann, Matthias, Winklhofer, K. F., Hartl, F. U. & Hipp, M. S., 8 Jan 2016, In: Science (New York, N.Y.). 351, 6269, p. 173-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    66. 2015
    67. Published

      Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

      Bassani-Sternberg, M., Pletscher-Frankild, S., Jensen, Lars Juhl & Mann, Matthias, Mar 2015, In: Molecular and Cellular Proteomics. 14, 3, p. 658-73 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    68. Published

      Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors

      Deshmukh, Atul Shahaji, Murgia, M., Nagaraja, N., Treebak, Jonas Thue, Cox, J. & Mann, Matthias, Apr 2015, In: Molecular and Cellular Proteomics. 14, 4, p. 841-853

      Research output: Contribution to journal › Journal article › Research › peer-review

    69. Published

      Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow

      Deshmukh, Atul Shahaji, Cox, J., Jensen, Lars Juhl, Meissner, F. & Mann, Matthias, 6 Nov 2015, In: Journal of Proteome Research. 14, 11, p. 4885-95 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    70. Published

      Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells

      Ding, L., Paszkowski-Rogacz, M., Winzi, M., Chakraborty, D., Theis, M., Singh, S., Ciotta, G., Poser, I., Roguev, A., Chu, W. K., Choudhary, Chunaram, Mann, Matthias, Stewart, A. F., Krogan, N. & Buchholz, F., 26 Aug 2015, In: Cell Systems. 1, 2, p. 141-151 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    71. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy

      Gramlich, M., Pane, L. S., Zhou, Q., Chen, Z., Murgia, M., Schötterl, S., Goedel, A., Metzger, K., Brade, T., Parrotta, E., Schaller, M., Gerull, B., Thierfelder, L., Aartsma-Rus, A., Labeit, S., Atherton, J. J., McGaughran, J., Harvey, R. P., Sinnecker, D., Mann, M. & 3 others, Laugwitz, K., Gawaz, M. P. & Moretti, A., 9 Mar 2015, In: EMBO Molecular Medicine. 7, 5, p. 562-576 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    72. A double-barrel LC-MS/MS system to quantify 96 interactomes per day

      Hosp, F., Scheltema, R. A., Eberl, C., Kulak, N. A., Keilhauer, E. C., Mayr, K. & Mann, Matthias, 17 Apr 2015, In: Molecular and Cellular Proteomics. 14, 7, p. 2030-41 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    73. Published

      Single muscle fiber proteomics reveals unexpected mitochondrial specialization

      Murgia, M., Nagaraj, N., Deshmukh, Atul Shahaji, Zeiler, M., Cancellara, P., Moretti, I., Reggiani, C., Schiaffino, S. & Mann, Matthias, 1 Mar 2015, In: E M B O Reports. 16, 3, p. 387-95 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    74. Published

      Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

      Räschle, M., Smeenk, G., Hansen, R. K., Temu, T., Oka, Y., Hein, M. Y., Nagaraj, N., Long, D. T., Walter, J. C., Hofmann, K., Storchova, Z., Cox, J., Bekker-Jensen, Simon Holst, Mailand, Niels & Mann, Matthias, 2015, In: Science. 348, 6234, p. 539- 10 p., 1253671.

      Research output: Contribution to journal › Journal article › Research › peer-review

    75. Published

      Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle

      Schiaffino, S., Reggiani, C., Kostrominova, T. Y., Mann, Matthias & Murgia, M., Dec 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Suppl 4, p. 41-8 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    76. 2014
    77. Published

      The growing landscape of lysine acetylation links metabolism and cell signalling

      Choudhary, Chunaram, Weinert, B. T., Nishida, Y., Verdin, E. & Mann, Matthias, 23 Jul 2014, In: Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    78. Published

      Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β

      J D'Souza, R. C., Knittle, A. M., Nagaraj, N., van Dinther, M., Choudhary, Chunaram, Ten Dijke, P., Mann, Matthias & Sharma, K., Jul 2014, In: Science Signaling. 7, 335, p. rs5 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    79. Published

      Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry

      Jungmichel, S., Sylvestersen, K. B., Choudhary, Chunaram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In: Cell Reports. 6, 3, p. 578-91 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    80. Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome

      Ripaud, L., Chumakova, V., Antonin, M., Hastie, A. R., Pinkert, S., Körner, R., Ruff, K. M., Pappu, R. V., Hornburg, D., Mann, Matthias, Hartl, F. U. & Hipp, M. S., 23 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18219-24 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    81. 2013

    82. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility

      Bassik, M. C., Kampmann, M., Lebbink, R. J., Wang, S., Hein, M. Y., Poser, I., Weibezahn, J., Horlbeck, M. A., Chen, S., Mann, Matthias, Hyman, A. A., Leproust, E. M., McManus, M. T. & Weissman, J. S., 14 Feb 2013, In: Cell. 152, 4, p. 909-22 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    83. Published

      Quantification of the N-glycosylated secretome by super-SILAC during breast cancer progression and in human blood Samples

      Boersema, P. J., Geiger, T., Wiśniewski, J. R. & Mann, Matthias, 1 Jan 2013, In: Molecular & Cellular Proteomics. 12, 1, p. 158-171 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    84. DEAD box protein DDX1 regulates cytoplasmic localization of KSRP

      Chou, C., Lin, W., Lin, C., Luber, C. A., Godbout, R., Mann, Matthias & Chen, C., 4 Sep 2013, In: P L o S One. 8, 9, e73752.

      Research output: Contribution to journal › Journal article › Research

    85. N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes

      Deeb, S. J., Cox, J., Schmidt-Supprian, M. & Mann, Matthias, 4 Nov 2013, In: Molecular & Cellular Proteomics.

      Research output: Contribution to journal › Journal article › Research › peer-review

    86. Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse

      Geiger, T., Velic, A., Macek, B., Lundberg, E., Kampf, C., Nagaraj, N., Uhlen, M., Cox, J. & Mann, Matthias, Jun 2013, In: Molecular & Cellular Proteomics. 12, 6, p. 1709-22 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    87. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15

      Hirst, J., Borner, G. H. H., Edgar, J., Hein, M. Y., Mann, Matthias, Buchholz, F., Antrobus, R. & Robinson, M. S., Aug 2013, In: Molecular Biology of the Cell. 24, 16, p. 2558-69 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    88. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

      Kappei, D., Butter, F., Benda, C., Scheibe, M., Draškovič, I., Stevense, M., Novo, C. L., Basquin, C., Araki, M., Araki, K., Krastev, D. B., Kittler, R., Jessberger, R., Londoño-Vallejo, J. A., Mann, Matthias & Buchholz, F., 12 Jun 2013, In: E M B O Journal. 32, 12, p. 1681-701 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    89. Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae

      Klass, D. M., Scheibe, M., Butter, F., Hogan, G. J., Mann, Matthias & Brown, P. O., Jun 2013, In: Genome Research. 23, 6, p. 1028-38 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    90. Protein correlation profiles identify lipid droplet proteins with high confidence

      Krahmer, N., Hilger, M., Kory, N., Wilfling, F., Stoehr, G., Mann, Matthias, Farese, R. V. & Walther, T. C., May 2013, In: Molecular & Cellular Proteomics. 12, 5, p. 1115-26 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    91. The proteome of the calcified layer organic matrix of turkey (Meleagris gallopavo) eggshell

      Mann, K. & Mann, Matthias, 2013, In: Proteome Science. 11, 1, p. 40

      Research output: Contribution to journal › Journal article › Research › peer-review

    92. Published

      The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

      Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In: Molecular Cell. 49, 4, p. 583-590 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    93. A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics

      Marx, H., Lemeer, S., Schliep, J. E., Matheron, L., Mohammed, S., Cox, J., Mann, Matthias, Heck, A. J. R. & Kuster, B., Jun 2013, In: Nature Biotechnology. 31, 6, p. 557-64 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    94. Direct proteomic quantification of the secretome of activated immune cells

      Meissner, F., Scheltema, R. A., Mollenkopf, H. & Mann, Matthias, 26 Apr 2013, In: Science (New York, N.Y.). 340, 6131, p. 475-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    95. High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome

      Neuhauser, N., Nagaraj, N., McHardy, P., Zanivan, S., Scheltema, R., Cox, J. & Mann, Matthias, 7 Jun 2013, In: Journal of Proteome Research. 12, 6, p. 2858-68 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    96. Published

      Status of large-scale analysis of post-translational modifications by mass spectrometry

      Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In: Molecular & Cellular Proteomics. 12, p. 3444-52

      Research output: Contribution to journal › Journal article › Research › peer-review

    97. Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins

      Pasini, E. M., Braks, J. A., Fonager, J., Klop, O., Aime, E., Spaccapelo, R., Otto, T. D., Berriman, M., Hiss, J. A., Thomas, A. W., Mann, Matthias, Janse, C. J., Kocken, C. H. M. & Franke-Fayard, B., Feb 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 426-48 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    98. Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment

      Powers, N. R., Eicher, J. D., Butter, F., Kong, Y., Miller, L. L., Ring, S. M., Mann, Matthias & Gruen, J. R., 11 Jul 2013, In: American Journal of Human Genetics. 93, 1, p. 19-28 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    99. Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

      Radovanac, K., Morgner, J., Schulz, J., Blumbach, K., Patterson, C., Geiger, T., Mann, Matthias, Krieg, T., Eckes, B., Fässler, R. & Wickström, S. A., 15 May 2013, In: E M B O Journal. 32, 10, p. 1409-24 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    100. Proteomic approaches in circadian biology

      Robles, M. S. & Mann, Matthias, 2013, Handbook of experimental pharmacology: Circadian Clocks. p. 389-407 19 p. (Handbook of Experimental Pharmacology).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

    101. Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators

      Scheibe, M., Arnoult, N., Kappei, D., Buchholz, F., Decottignies, A., Butter, F. & Mann, Matthias, 22 Oct 2013, In: Genome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    102. Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators

      Scheibe, M., Arnoult, N., Kappei, D., Buchholz, F., Decottignies, A., Butter, F. & Mann, Matthias, 22 Oct 2013, In: Genome Research.

      Research output: Contribution to journal › Journal article › Research › peer-review

    103. β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

      Schiller, H. B., Hermann, M., Polleux, J., Vignaud, T., Zanivan, S., Friedel, C. C., Sun, Z., Raducanu, A., Gottschalk, K., Théry, M., Mann, Matthias & Fässler, R., Jun 2013, In: Nature Cell Biology. 15, 6, p. 625-36 12 p.

      Research output: Contribution to journal › Journal article › Research

    104. The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

      Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, Matthias, Knoblich, J. A. & van Lohuizen, M., 29 May 2013, In: E M B O Journal. 32, 11, p. 1598-612 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    105. A SILAC-based approach identifies substrates of caspase-dependent cleavage upon TRAIL-induced apoptosis

      Stoehr, G., Schaab, C., Graumann, J. & Mann, Matthias, May 2013, In: Molecular & Cellular Proteomics. 12, 5, p. 1436-50 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    106. Published

      The SH2 domain interaction landscape

      Tinti, M., Kiemer, L., Costa, S., Miller, M. L., Sacco, F., Olsen, Jesper Velgaard, Carducci, M., Paoluzi, S., Langone, F., Workman, C., Blom, N., Machida, K., Thompson, C. M., Schutkowski, M., Brunak, Søren, Mann, Matthias, Mayer, B. J., Castagnoli, L. & Cesareni, G., 2013, In: Cell Reports. 3, 4, p. 1293-1305 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 5650809