Matthias Mann

Matthias Mann

Professor, head of research, Professor


  1. 1994
  2. Published

    Error-tolerant identification of peptides in sequence databases by peptide sequence tags

    Mann, Matthias & Wilm, M., 15 Dec 1994, In: Analytical Chemistry. 66, 24, p. 4390-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 1996
  4. Published

    Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

    Wilm, M., Shevchenko, A., Houthaeve, T., Breit, S., Schweigerer, L., Fotsis, T. & Mann, Matthias, 1 Feb 1996, In: Nature. 379, 6564, p. 466-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 1997
  6. Identification of a novel membrane protein that interacts specifically with the upar-prourokinase complex

    Behrendt, Niels, Engelholm, Lars Henning, Jensen, O. N., Mörtz, E., Ranne, E., Mann, Matthias & Dan, K., 1997, In: Fibrinolysis and Proteolysis. 11, Supl. 3, p. 10 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  7. 2000
  8. A urokinase receptor-associated protein with specific collagen binding properties

    Behrendt, Niels, Jensen, O. N., Engelholm, Lars Henning, Mørtz, E., Mann, Matthias & Danø, K., 2000, In: The Journal of Biological Chemistry. 275, 3, p. 1993-2002 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2003
  10. Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry

    Hinsby, A. M., Olsen, Jesper Velgaard, Bennett, K. L. & Mann, Matthias, 2003, In: Molecular and Cellular Proteomics. 2, 1, p. 29-36 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria

    Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2004
  13. Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4

    Hinsby, A. M., Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Journal of Biological Chemistry. 279, 45, p. 46438-47 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain

    Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation

    Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Trypsin cleaves exclusively C-terminal to arginine and lysine residues

    Olsen, Jesper Velgaard, Ong, S. & Mann, Matthias, 2004, In: Molecular and Cellular Proteomics. 3, 6, p. 608-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2005
  18. Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway

    Gruhler, A., Olsen, Jesper Velgaard, Mohammed, S., Mortensen, P., Faergeman, N. J., Mann, Matthias & Jensen, O. N., 2005, In: Molecular and Cellular Proteomics. 4, 3, p. 310-27 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Proteomic mapping of brain plasma membrane proteins

    Nielsen, P. A., Olsen, Jesper Velgaard, Podtelejnikov, A. V., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 402-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap

    Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2006
  22. The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins

    Adachi, J., Kumar, C., Zhang, Y., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Genome Biology. 7, 9, p. R80

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Actin homolog MreB and RNA polymerase interact and are both required for chromosome segregation in Escherichia coli

    Kruse, Thomas, Blagoev, B., Løbner-Olesen, Anders, Wachi, M., Sasaki, K., Iwai, N., Mann, Matthias & Gerdes, K., 1 Jan 2006, In: Genes & Development. 20, 1, p. 113-124 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer

    Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

    Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. In-gel digestion for mass spectrometric characterization of proteins and proteomes

    Shevchenko, A., Tomas, H., Havlis, J., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Nature Protocols (Print Edition). 1, 6, p. 2856-60 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system

    de Godoy, L. M. F., Olsen, Jesper Velgaard, de Souza, G. A., Li, G., Mortensen, P. & Mann, Matthias, 2006, In: Genome Biology. 7, 6, p. R50

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2007
  29. Quantitative proteomic assessment of very early cellular signaling events

    Dengjel, J., Akimov, V., Olsen, Jesper Velgaard, Bunkenborg, J., Mann, Matthias, Blagoev, B. & Andersen, J. S., 2007, In: Nature Biotechnology. 25, 5, p. 566-8 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites

    Gnad, F., Ren, S., Cox, J., Olsen, Jesper Velgaard, Macek, B., Oroshi, M. & Mann, Matthias, 2007, In: Genome Biology. 8, 11, p. R250

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. The low molecular weight proteome of Halobacterium salinarum

    Klein, C., Aivaliotis, M., Olsen, Jesper Velgaard, Falb, M., Besir, H., Scheffer, B., Bisle, B., Tebbe, A., Konstantinidis, K., Siedler, F., Pfeiffer, F., Mann, Matthias & Oesterhelt, D., 2007, In: Journal of Proteome Research. 6, 4, p. 1510-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Noncovalent interaction between Ubc9 and SUMO promotes SUMO chain formation

    Knipscheer, P., van Dijk, W. J., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: EMBO Journal. 26, 11, p. 2797-807 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Nanoelectrospray peptide mapping revisited: Composite survey spectra allow high dynamic range protein characterization without LCMS on an orbitrap mass spectrometer

    Lu, A., Waanders, L. F., Almeida, R., Li, G., Allen, M., Cox, J., Olsen, Jesper Velgaard, Bonaldi, T. & Mann, Matthias, 1 Dec 2007, In: International Journal of Mass Spectrometry. 268, 2-3, p. 158-167 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation

    Macek, B., Gnad, F., Soufi, B., Kumar, C., Olsen, Jesper Velgaard, Mijakovic, I. & Mann, Matthias, 2007, In: Molecular and Cellular Proteomics. 7, 2, p. 299-307 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Phosphoproteins of the chicken eggshell calcified layer

    Mann, K., Olsen, Jesper Velgaard, Macek, B., Gnad, F. & Mann, Matthias, 2007, In: Proteomics. 7, 1, p. 106-15 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification

    Notenboom, V., Hibbert, R. G., van Rossum-Fikkert, S. E., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: Nucleic Acids Research. 35, 17, p. 5819-30 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Higher-energy C-trap dissociation for peptide modification analysis

    Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Quantitative proteomic profiling of membrane proteins from the mouse brain cortex, hippocampus, and cerebellum using the HysTag reagent: mapping of neurotransmitter receptors and ion channels

    Olsen, Jesper Velgaard, Nielsen, P. A., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2007, In: Brain Research. 1134, 1, p. 95-106 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. A mass spectrometry-friendly database for cSNP identification

    Schandorff, S., Olsen, Jesper Velgaard, Bunkenborg, J., Blagoev, B., Zhang, Y., Andersen, J. S. & Mann, Matthias, 2007, In: Nature Methods. 4, 6, p. 465-6 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. MAPU: Max-Planck Unified database of organellar, cellular, tissue and body fluid proteomes

    Zhang, Y., Zhang, Y., Adachi, J., Olsen, Jesper Velgaard, Shi, R., de Souza, G., Pasini, E., Foster, L. J., Macek, B., Zougman, A., Kumar, C., Wisniewski, J. R., Jun, W. & Mann, Matthias, Jan 2007, In: Nucleic Acids Research. 35, Database issue, p. D771-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 2008
  42. The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis

    Macek, B., Mijakovic, I., Olsen, Jesper Velgaard, Gnad, F., Kumar, C., Jensen, P. R. & Mann, Matthias, Feb 2008, In: Molecular and Cellular Proteomics. 6, 4, p. 697-707 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis

    Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors

    Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2009
  46. Published

    Lysine acetylation targets protein complexes and co-regulates major cellular functions

    Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Mislocalized activation of oncogenic RTKs switches downstream signaling outcomes

    Choudhary, Chunaram, Olsen, Jesper Velgaard, Brandts, C., Cox, J., Reddy, P. N. G., Böhmer, F. D., Gerke, V., Schmidt-Arras, D., Berdel, W. E., Müller-Tidow, C., Mann, Matthias & Serve, H., 2009, In: Molecular Cell. 36, 2, p. 326-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast

    Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Proteomics. 9, 20, p. 4642-4652 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Global and site-specific quantitative phosphoproteomics: principles and applications

    Macek, B., Mann, Matthias & Olsen, J. V., 2009, In: Annual Review of Pharmacology and Toxicology. 49, p. 199-221 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

    Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics

    Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. 2010
  53. Published

    Decoding signalling networks by mass spectrometry-based proteomics

    Choudhary, Chunaram & Mann, Matthias, 1 Jun 2010, In: Nature Reviews. Molecular Cell Biology. 11, 6, p. 427-39 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics

    Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis

    Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Yeast expression proteomics by high-resolution mass spectrometry

    Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2010, In: Methods in Enzymology. 470, p. 259-80 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. 2011
  58. Published

    Quantitative, high-resolution proteomics for data-driven systems biology

    Cox, J. & Mann, Matthias, 7 Jul 2011, In: Annual Review of Biochemistry. 80, p. 273-299 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Andromeda - a peptide search engine integrated into the MaxQuant environment

    Cox, J., Neuhauser, N., Michalski, A., Scheltema, R. A., Olsen, Jesper Velgaard & Mann, Matthias, 1 Apr 2011, In: Journal of Proteome Research. 10, 4, p. 1794-805 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community

    Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In: Science Signaling. 4, 160, p. pe7

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation

    Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2012
  64. Published

    Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response

    Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, Jesper Velgaard, Baskcomb, L., Mann, Matthias, Jackson, S. P. & Choudhary, Chunaram, 2012, In: Molecular Cell. 46, 2, p. 212-25 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 1D and 2D annotation enrichment: a statistical method integrating quantitative proteomics with complementary high-throughput data

    Cox, J. & Mann, Matthias, 2012, In: B M C Bioinformatics. 13 Suppl 16, p. S12

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Advancing cell biology through proteomics in space and time (PROSPECTS)

    Lamond, A. I., Uhlen, M., Horning, S., Makarov, A., Robinson, C. V., Serrano, L., Hartl, F. U., Baumeister, W., Werenskiold, A. K., Mann, Matthias, Andersen, J. S., Vorm, O., Linial, M. & Aebersold, R., 1 Mar 2012, In: Molecular & Cellular Proteomics. 11, 3, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Proteomics for biomedicine: A half-completed journey

    Mann, Matthias, 1 Feb 2012, In: EMBO Molecular Medicine. 4, 2, p. 75-77 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation

    Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In: Journal of Proteome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma

    Wiśniewski, J. R., Ostasiewicz, P., Duś, K., Zielińska, D. F., Gnad, F. & Mann, Matthias, 1 Jan 2012, In: Molecular Systems Biology. 8, 611.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. 2013
  71. A systematic mammalian genetic interaction map reveals pathways underlying ricin susceptibility

    Bassik, M. C., Kampmann, M., Lebbink, R. J., Wang, S., Hein, M. Y., Poser, I., Weibezahn, J., Horlbeck, M. A., Chen, S., Mann, Matthias, Hyman, A. A., Leproust, E. M., McManus, M. T. & Weissman, J. S., 14 Feb 2013, In: Cell. 152, 4, p. 909-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Quantification of the N-glycosylated secretome by super-SILAC during breast cancer progression and in human blood Samples

    Boersema, P. J., Geiger, T., Wiśniewski, J. R. & Mann, Matthias, 1 Jan 2013, In: Molecular & Cellular Proteomics. 12, 1, p. 158-171 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. DEAD box protein DDX1 regulates cytoplasmic localization of KSRP

    Chou, C., Lin, W., Lin, C., Luber, C. A., Godbout, R., Mann, Matthias & Chen, C., 4 Sep 2013, In: P L o S One. 8, 9, e73752.

    Research output: Contribution to journalJournal articleResearch

  74. N-linked glycosylation enrichment for in-depth cell surface proteomics of diffuse large B-cell lymphoma subtypes

    Deeb, S. J., Cox, J., Schmidt-Supprian, M. & Mann, Matthias, 4 Nov 2013, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Initial quantitative proteomic map of 28 mouse tissues using the SILAC mouse

    Geiger, T., Velic, A., Macek, B., Lundberg, E., Kampf, C., Nagaraj, N., Uhlen, M., Cox, J. & Mann, Matthias, Jun 2013, In: Molecular & Cellular Proteomics. 12, 6, p. 1709-22 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Interaction between AP-5 and the hereditary spastic paraplegia proteins SPG11 and SPG15

    Hirst, J., Borner, G. H. H., Edgar, J., Hein, M. Y., Mann, Matthias, Buchholz, F., Antrobus, R. & Robinson, M. S., Aug 2013, In: Molecular Biology of the Cell. 24, 16, p. 2558-69 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

    Kappei, D., Butter, F., Benda, C., Scheibe, M., Draškovič, I., Stevense, M., Novo, C. L., Basquin, C., Araki, M., Araki, K., Krastev, D. B., Kittler, R., Jessberger, R., Londoño-Vallejo, J. A., Mann, Matthias & Buchholz, F., 12 Jun 2013, In: E M B O Journal. 32, 12, p. 1681-701 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Quantitative proteomic analysis reveals concurrent RNA-protein interactions and identifies new RNA-binding proteins in Saccharomyces cerevisiae

    Klass, D. M., Scheibe, M., Butter, F., Hogan, G. J., Mann, Matthias & Brown, P. O., Jun 2013, In: Genome Research. 23, 6, p. 1028-38 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Protein correlation profiles identify lipid droplet proteins with high confidence

    Krahmer, N., Hilger, M., Kory, N., Wilfling, F., Stoehr, G., Mann, Matthias, Farese, R. V. & Walther, T. C., May 2013, In: Molecular & Cellular Proteomics. 12, 5, p. 1115-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. The proteome of the calcified layer organic matrix of turkey (Meleagris gallopavo) eggshell

    Mann, K. & Mann, Matthias, 2013, In: Proteome Science. 11, 1, p. 40

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    The Coming Age of Complete, Accurate, and Ubiquitous Proteomes

    Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In: Molecular Cell. 49, 4, p. 583-590 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics

    Marx, H., Lemeer, S., Schliep, J. E., Matheron, L., Mohammed, S., Cox, J., Mann, Matthias, Heck, A. J. R. & Kuster, B., Jun 2013, In: Nature Biotechnology. 31, 6, p. 557-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Direct proteomic quantification of the secretome of activated immune cells

    Meissner, F., Scheltema, R. A., Mollenkopf, H. & Mann, Matthias, 26 Apr 2013, In: Science (New York, N.Y.). 340, 6131, p. 475-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. High performance computational analysis of large-scale proteome data sets to assess incremental contribution to coverage of the human genome

    Neuhauser, N., Nagaraj, N., McHardy, P., Zanivan, S., Scheltema, R., Cox, J. & Mann, Matthias, 7 Jun 2013, In: Journal of Proteome Research. 12, 6, p. 2858-68 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Status of large-scale analysis of post-translational modifications by mass spectrometry

    Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In: Molecular & Cellular Proteomics. 12, p. 3444-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins

    Pasini, E. M., Braks, J. A., Fonager, J., Klop, O., Aime, E., Spaccapelo, R., Otto, T. D., Berriman, M., Hiss, J. A., Thomas, A. W., Mann, Matthias, Janse, C. J., Kocken, C. H. M. & Franke-Fayard, B., Feb 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 426-48 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment

    Powers, N. R., Eicher, J. D., Butter, F., Kong, Y., Miller, L. L., Ring, S. M., Mann, Matthias & Gruen, J. R., 11 Jul 2013, In: American Journal of Human Genetics. 93, 1, p. 19-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

    Radovanac, K., Morgner, J., Schulz, J., Blumbach, K., Patterson, C., Geiger, T., Mann, Matthias, Krieg, T., Eckes, B., Fässler, R. & Wickström, S. A., 15 May 2013, In: E M B O Journal. 32, 10, p. 1409-24 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Proteomic approaches in circadian biology

    Robles, M. S. & Mann, Matthias, 2013, Handbook of experimental pharmacology: Circadian Clocks. p. 389-407 19 p. (Handbook of Experimental Pharmacology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  90. Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators

    Scheibe, M., Arnoult, N., Kappei, D., Buchholz, F., Decottignies, A., Butter, F. & Mann, Matthias, 22 Oct 2013, In: Genome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Quantitative interaction screen of telomeric repeat-containing RNA reveals novel TERRA regulators

    Scheibe, M., Arnoult, N., Kappei, D., Buchholz, F., Decottignies, A., Butter, F. & Mann, Matthias, 22 Oct 2013, In: Genome Research.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

    Schiller, H. B., Hermann, M., Polleux, J., Vignaud, T., Zanivan, S., Friedel, C. C., Sun, Z., Raducanu, A., Gottschalk, K., Théry, M., Mann, Matthias & Fässler, R., Jun 2013, In: Nature Cell Biology. 15, 6, p. 625-36 12 p.

    Research output: Contribution to journalJournal articleResearch

  93. The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation

    Sparmann, A., Xie, Y., Verhoeven, E., Vermeulen, M., Lancini, C., Gargiulo, G., Hulsman, D., Mann, Matthias, Knoblich, J. A. & van Lohuizen, M., 29 May 2013, In: E M B O Journal. 32, 11, p. 1598-612 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. A SILAC-based approach identifies substrates of caspase-dependent cleavage upon TRAIL-induced apoptosis

    Stoehr, G., Schaab, C., Graumann, J. & Mann, Matthias, May 2013, In: Molecular & Cellular Proteomics. 12, 5, p. 1436-50 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    The SH2 domain interaction landscape

    Tinti, M., Kiemer, L., Costa, S., Miller, M. L., Sacco, F., Olsen, Jesper Velgaard, Carducci, M., Paoluzi, S., Langone, F., Workman, C., Blom, N., Machida, K., Thompson, C. M., Schutkowski, M., Brunak, Søren, Mann, Matthias, Mayer, B. J., Castagnoli, L. & Cesareni, G., 2013, In: Cell Reports. 3, 4, p. 1293-1305 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Phosphorylation Variation during the Cell Cycle Scales with Structural Propensities of Proteins

    Tyanova, S., Frishman, D., Cox, J., Mann, Matthias & Olsen, Jesper Velgaard, 10 Jan 2013, In: P L o S Computational Biology (Online). 9, 1, p. e1002842 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. A DNA-Centric Protein Interaction Map of Ultraconserved Elements Reveals Contribution of Transcription Factor Binding Hubs to Conservation

    Viturawong, T., Meissner, F., Butter, F. & Mann, Matthias, 31 Oct 2013, In: Plant Cell Reports. 5, 2, p. 531-45 15 p.

    Research output: Contribution to journalJournal articleResearch

  98. Published

    In Vivo SILAC-Based Proteomics Reveals Phosphoproteome Changes during Mouse Skin Carcinogenesis

    Zanivan, S., Meves, A., Behrendt, K., Schoof, E., Neilson, L. J., Cox, J., Tang, H. R., Kalna, G., van Ree, J. H., van Deursen, J. M., Trempus, C. S., Machesky, L. M., Linding, R., Wickström, S. A., Fässler, R. & Mann, Matthias, 21 Feb 2013, In: Cell Reports. 3, 2, p. 552-566 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers

    Zanivan, S., Maione, F., Hein, M. Y., Hernández-Fernaud, J. R., Ostasiewicz, P., Giraudo, E. & Mann, Matthias, 26 Aug 2013, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. 2014
  101. Published

    The growing landscape of lysine acetylation links metabolism and cell signalling

    Choudhary, Chunaram, Weinert, B. T., Nishida, Y., Verdin, E. & Mann, Matthias, 23 Jul 2014, In: Nature Reviews. Molecular Cell Biology. 15, 8, p. 536-50 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  102. Published

    Time-resolved dissection of early phosphoproteome and ensuing proteome changes in response to TGF-β

    J D'Souza, R. C., Knittle, A. M., Nagaraj, N., van Dinther, M., Choudhary, Chunaram, Ten Dijke, P., Mann, Matthias & Sharma, K., Jul 2014, In: Science Signaling. 7, 335, p. rs5 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry

    Jungmichel, S., Sylvestersen, K. B., Choudhary, Chunaram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In: Cell Reports. 6, 3, p. 578-91 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome

    Ripaud, L., Chumakova, V., Antonin, M., Hastie, A. R., Pinkert, S., Körner, R., Ruff, K. M., Pappu, R. V., Hornburg, D., Mann, Matthias, Hartl, F. U. & Hipp, M. S., 23 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18219-24 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. 2015
  106. Published

    Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

    Bassani-Sternberg, M., Pletscher-Frankild, S., Jensen, Lars Juhl & Mann, Matthias, Mar 2015, In: Molecular and Cellular Proteomics. 14, 3, p. 658-73 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Deep proteomics of mouse skeletal muscle enables quantitation of protein isoforms, metabolic pathways and transcription factors

    Deshmukh, Atul Shahaji, Murgia, M., Nagaraja, N., Treebak, Jonas Thue, Cox, J. & Mann, Matthias, Apr 2015, In: Molecular and Cellular Proteomics. 14, 4, p. 841-853

    Research output: Contribution to journalJournal articleResearchpeer-review

  108. Published

    Secretome Analysis of Lipid-Induced Insulin Resistance in Skeletal Muscle Cells by a Combined Experimental and Bioinformatics Workflow

    Deshmukh, Atul Shahaji, Cox, J., Jensen, Lars Juhl, Meissner, F. & Mann, Matthias, 6 Nov 2015, In: Journal of Proteome Research. 14, 11, p. 4885-95 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Systems Analyses Reveal Shared and Diverse Attributes of Oct4 Regulation in Pluripotent Cells

    Ding, L., Paszkowski-Rogacz, M., Winzi, M., Chakraborty, D., Theis, M., Singh, S., Ciotta, G., Poser, I., Roguev, A., Chu, W. K., Choudhary, Chunaram, Mann, Matthias, Stewart, A. F., Krogan, N. & Buchholz, F., 26 Aug 2015, In: Cell Systems. 1, 2, p. 141-151 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy

    Gramlich, M., Pane, L. S., Zhou, Q., Chen, Z., Murgia, M., Schötterl, S., Goedel, A., Metzger, K., Brade, T., Parrotta, E., Schaller, M., Gerull, B., Thierfelder, L., Aartsma-Rus, A., Labeit, S., Atherton, J. J., McGaughran, J., Harvey, R. P., Sinnecker, D., Mann, M. & 3 others, Laugwitz, K., Gawaz, M. P. & Moretti, A., 9 Mar 2015, In: EMBO Molecular Medicine. 7, 5, p. 562-576 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. A double-barrel LC-MS/MS system to quantify 96 interactomes per day

    Hosp, F., Scheltema, R. A., Eberl, C., Kulak, N. A., Keilhauer, E. C., Mayr, K. & Mann, Matthias, 17 Apr 2015, In: Molecular and Cellular Proteomics. 14, 7, p. 2030-41 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  112. Published

    Single muscle fiber proteomics reveals unexpected mitochondrial specialization

    Murgia, M., Nagaraj, N., Deshmukh, Atul Shahaji, Zeiler, M., Cancellara, P., Moretti, I., Reggiani, C., Schiaffino, S. & Mann, Matthias, 1 Mar 2015, In: E M B O Reports. 16, 3, p. 387-95 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Proteomics reveals dynamic assembly of repair complexes during bypass of DNA cross-links

    Räschle, M., Smeenk, G., Hansen, R. K., Temu, T., Oka, Y., Hein, M. Y., Nagaraj, N., Long, D. T., Walter, J. C., Hofmann, K., Storchova, Z., Cox, J., Bekker-Jensen, Simon Holst, Mailand, Niels & Mann, Matthias, 2015, In: Science. 348, 6234, p. 539- 10 p., 1253671.

    Research output: Contribution to journalJournal articleResearchpeer-review

  114. Published

    Mitochondrial specialization revealed by single muscle fiber proteomics: focus on the Krebs cycle

    Schiaffino, S., Reggiani, C., Kostrominova, T. Y., Mann, Matthias & Murgia, M., Dec 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Suppl 4, p. 41-8 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  115. 2016
  116. Published

    Mass-spectrometric exploration of proteome structure and function

    Aebersold, R. & Mann, Matthias, 15 Sep 2016, In: Nature. 537, 7620, p. 347-55 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry

    Bassani-Sternberg, M., Bräunlein, E., Klar, R., Engleitner, T., Sinitcyn, P., Audehm, S., Straub, M., Weber, J., Slotta-Huspenina, J., Specht, K., Martignoni, M. E., Werner, A., Hein, R., H Busch, D., Peschel, C., Rad, R., Cox, J., Mann, Matthias & Krackhardt, A. M., 21 Nov 2016, In: Nature Communications. 7, p. 13404

    Research output: Contribution to journalJournal articleResearchpeer-review

  118. Published

    C/EBPα creates elite cells for iPSC reprogramming by upregulating Klf4 and increasing the levels of Lsd1 and Brd4

    Di Stefano, B., Collombet, S., Jakobsen, J. S., Wierer, M., Sardina, J. L., Lackner, A., Stadhouders, R., Segura-Morales, C., Francesconi, M., Limone, F., Mann, Matthias, Porse, Bo Torben, Thieffry, D. & Graf, T., Apr 2016, In: Nature Cell Biology. 18, 4, p. 371-81 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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