Jakob Nilsson
Professor
Nilsson Group
Blegdamsvej 3B
2200 København N
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A Consensus Binding Motif for the PP4 Protein Phosphatase
Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6Research output: Contribution to journal › Journal article › Research › peer-review
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A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.Research output: Contribution to journal › Journal article › Research › peer-review
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A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment
Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290Research output: Contribution to journal › Journal article › Research › peer-review
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A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Y., Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In: eLife. 9, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis
Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.Research output: Contribution to journal › Journal article › Research › peer-review
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A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation
Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In: Journal of Cell Science. 127, p. 871-884Research output: Contribution to journal › Journal article › Research › peer-review
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.Research output: Contribution to journal › Journal article › Research › peer-review
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Bub1/BubR1: swiss army knives at kinetochores
Nilsson, Jakob, 11 Aug 2015, In: Cell Cycle. 14, 9, p. 2999-3000 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Can sequestering of mitotic spindle proteins cause aneuploidy? (Comment on DOI 10.1002/bies.201400175)
Nilsson, Jakob, Mar 2015, In: BioEssays. 37, 3, p. 234 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?
Nilsson, Jakob, 2011, In: BioEssays. 33, 12, p. 903-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061
Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development
Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, Jens Vilstrup, Hayward, D. G., Nilsson, Jakob, Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coupling of Cdc20 inhibition and activation by BubR1
Hein, J. B., Garvanska, Dimitriya Hristoforova, Nasa, I., Kettenbach, A. N. & Nilsson, Jakob, 2021, In: Journal of Cell Biology. 220, 5, e202012081.Research output: Contribution to journal › Journal article › Research › peer-review
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Cryo-EM structures of PP2A:B55–FAM122A and PP2A:B55–ARPP19
Padi, S. K. R., Vos, M. R., Godek, R. J., Fuller, J. R., Kruse, Thomas, Hein, J. B., Nilsson, Jakob, Kelker, M. S., Page, R. & Peti, W., 2024, In: Nature. 625, 7993, p. 195-203 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression
Kruse, Thomas, Zhang, G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, Jakob, 23 Jan 2013, In: Journal of Cell Science. 126, p. 1086-1092 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
Zhang, G., Lischetti, T., Hayward, D. G. & Nilsson, Jakob, 2 Jun 2015, In: Nature Communications. 6, 14 p., 7162.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis
Hein, J. B., Hertz, Emil Peter Thrane, Garvanska, Dimitriya Hristoforova, Kruse, Thomas & Nilsson, Jakob, 2017, In: Nature Cell Biology. 19, p. 1433-1440Research output: Contribution to journal › Journal article › Research › peer-review
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Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex
Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.Research output: Contribution to journal › Journal article › Research › peer-review
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Escape from the checkpoint: Nek2A binds a unique conformation of the APC/C-MCC complex
Nilsson, Jakob, 2020, In: EMBO Reports. 21, 6, e50494.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Zhang, Y., Young, R., Garvanska, Dimitriya Hristoforova, Song, C., Zhai, Y., Wang, Y., Jiang, H., Fang, J., Nilsson, Jakob, Alfieri, C. & Zhang, G., 2024, In: Communications Biology . 7, 12 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review
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Generation and diversification of recombinant monoclonal antibodies
DeLuca, K. F., Mick, J. E., Ide, A. H., Lima, W. C., Sherman, L., Schaller, K. L., Anderson, S. M., Zhao, N., Stasevich, T. J., Varma, D., Nilsson, Jakob & DeLuca, J. G., 2021, In: eLife. 10, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8799501
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
122
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Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Research output: Contribution to journal › Journal article › Research › peer-review
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118
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A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Research output: Contribution to journal › Journal article › Research › peer-review
Published