Jakob Nilsson

Jakob Nilsson

Professor

ORCID: 0000-0003-4100-1125

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  1. Published

    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

    Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The RIF1-PP1 Axis Controls Abscission Timing in Human Cells

    Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

    Bolanos-Garcia, V. M., Nilsson, Jakob & Blundell, T. L., 1 Jan 2012, In: Bioarchitecture. 2, 1, p. 23-27 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site

    Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, Jakob & Blundell, T. L., 9 Nov 2011, In: Structure. 19, 11, p. 1691-700 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

    Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, Jakob, Mund, Andreas, Mann, Matthias & Curtis, M., 2018, In: Cell. 175, 1, p. 159-170.e16

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Generation and diversification of recombinant monoclonal antibodies

    DeLuca, K. F., Mick, J. E., Ide, A. H., Lima, W. C., Sherman, L., Schaller, K. L., Anderson, S. M., Zhao, N., Stasevich, T. J., Varma, D., Nilsson, Jakob & DeLuca, J. G., 2021, In: eLife. 10, 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    SAC during early cell divisions: Sacrificing fidelity over timely division, regulated differently across organisms Chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varying from species to species

    Duro, Joana Maria & Nilsson, Jakob, 2021, In: BioEssays. 43, 3, 13 p., 2000174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C

    Garvanska, Dimitriya Hristoforova, Larsen, Marie Sofie Yoo & Nilsson, Jakob, 2 Sep 2016, In: Biology Open. 5, p. 1441-1448

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

    Garvanska, Dimitriya Hristoforova & Nilsson, Jakob, 2020, In: Essays in Biochemistry. 64, 2, p. 325-336

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions

    Garvanska, D. H., Alvarado, R. E., Mundt, F. O., Lindqvist, R., Duel, J. K., Coscia, F., Nilsson, E., Lokugamage, K., Johnson, B. A., Plante, J. A., Morris, D. R., Vu, M. N., Estes, L. K., McLeland, A. M., Walker, J., Crocquet-Valdes, P. A., Mendez, B. L., Plante, K. S., Walker, D. H., Weisser, M. B. & 4 others, Överby, A. K., Mann, Matthias, Menachery, V. D. & Nilsson, Jakob, 2024, In: EMBO Reports.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

    Hein, J. B. & Nilsson, Jakob, 25 Jan 2014, In: E M B O Reports. 15, p. 264-272

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Distinct kinetics of serine and threonine dephosphorylation are essential for mitosis

    Hein, J. B., Hertz, Emil Peter Thrane, Garvanska, Dimitriya Hristoforova, Kruse, Thomas & Nilsson, Jakob, 2017, In: Nature Cell Biology. 19, p. 1433-1440

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Coupling of Cdc20 inhibition and activation by BubR1

    Hein, J. B., Garvanska, Dimitriya Hristoforova, Nasa, I., Kettenbach, A. N. & Nilsson, Jakob, 2021, In: Journal of Cell Biology. 220, 5, e202012081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry

    Hein, J. B. & Nilsson, Jakob, Mar 2016, In: Nature Communications. 7, 10 p., 10975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

    Hein, J. B., Nguyen, H. T., Garvanska, Dimitriya Hristoforova, Nasa, I., Kruse, Thomas, Feng, Y., Lopez Mendez, B., Davey, N., Kettenbach, A. N., Fordyce, P. M. & Nilsson, Jakob, 2023, In: Molecular Systems Biology. 19, 17 p., e11782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure

    Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase

    Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Localization of PP2A-B56 to centromeres in Drosophila

    Hertz, Emil Peter Thrane & Nilsson, Jakob, 3 Aug 2017, In: Cell Cycle. 16, 15, p. 1385-1386 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  20. Published

    Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions

    Kliche, J., Garvanska, Dimitriya Hristoforova, Simonetti, L., Badgujar, D., Dobritzsch, D., Nilsson, Jakob, Davey, N. E. & Ivarsson, Y., 2023, In: Molecular Systems Biology. 19, 7, 21 p., e11164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

    Kruse, Thomas, Gnosa, S. P., Nasa, I., Garvanska, Dimitriya Hristoforova, Hein, J. B., Nguyen, H., Samsøe-Petersen, Jacob, Lopez-Mendez, B., Hertz, Emil Peter Thrane, Schwarz, J., Pena, H. S., Nikodemus, D., Kveiborg, Marie, Kettenbach, A. N. & Nilsson, Jakob, 2020, In: EMBO Journal. 39, 18 p., e103695.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

    Kruse, Thomas, Biedenkopf, N., Hertz, Emil Peter Thrane, Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, Jakob & Becker, S., 4 Jan 2018, In: Molecular Cell. 69, 1, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment

    Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression

    Kruse, Thomas, Zhang, G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, Jakob, 23 Jan 2013, In: Journal of Cell Science. 126, p. 1086-1092 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

    Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

    Research output: Contribution to journal › Journal article › Research › peer-review

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