Jakob Nilsson

Jakob Nilsson

Professor

ORCID: 0000-0003-4100-1125

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  1. Published

    Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

    Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In: Nature Communications. 7, p. 1-12 12 p., 12256.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

    Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In: Oncogene. 32, 39, p. 4622-4633 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

    Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

    Lischetti, T., Zhang, G., Sedgwick, G. G., Bolanos-Garcia, V. M. & Nilsson, Jakob, Dec 2014, In: Nature Communications. 5, p. 1-12 12 p., 5563.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

    Zhang, G. & Nilsson, Jakob, 2018, In: Cell Cycle. 17, 9, p. 1087-1091

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication

    Bolanos-Garcia, V. M., Nilsson, Jakob & Blundell, T. L., 1 Jan 2012, In: Bioarchitecture. 2, 1, p. 23-27 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity

    Wild, T., Larsen, Marie Sofie Yoo, Narita, Takeo, Schou, J., Nilsson, Jakob & Choudhary, Chunaram, 1 Mar 2016, In: Cell Reports. 14, 8, p. 1829-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure

    Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The RIF1-PP1 Axis Controls Abscission Timing in Human Cells

    Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores

    Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In: Journal of Cell Science. p. 3243-3253 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions

    Garvanska, D. H., Alvarado, R. E., Mundt, F. O., Lindqvist, R., Duel, J. K., Coscia, F., Nilsson, E., Lokugamage, K., Johnson, B. A., Plante, J. A., Morris, D. R., Vu, M. N., Estes, L. K., McLeland, A. M., Walker, J., Crocquet-Valdes, P. A., Mendez, B. L., Plante, K. S., Walker, D. H., Weisser, M. B. & 4 others, Överby, A. K., Mann, Matthias, Menachery, V. D. & Nilsson, Jakob, 2024, In: EMBO Reports.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The Ebola Virus Nucleoprotein Recruits the Host PP2A-B56 Phosphatase to Activate Transcriptional Support Activity of VP30

    Kruse, Thomas, Biedenkopf, N., Hertz, Emil Peter Thrane, Dietzel, E., Stalmann, G., López-Méndez, B., Davey, N. E., Nilsson, Jakob & Becker, S., 4 Jan 2018, In: Molecular Cell. 69, 1, p. 136-145 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region

    Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In: P L o S One. 8, 4, p. e60596 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

    Nilsson, Jakob, Yekezare, M., Minshull, J. & Pines, J., 2008, In: Nature Cell Biology. 10, 12, p. 1411-20 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C

    Garvanska, Dimitriya Hristoforova, Larsen, Marie Sofie Yoo & Nilsson, Jakob, 2 Sep 2016, In: Biology Open. 5, p. 1441-1448

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site

    Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, Jakob & Blundell, T. L., 9 Nov 2011, In: Structure. 19, 11, p. 1691-700 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

    Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, Leitner, A. & Westermarck, J., 2023, In: Nature Communications. 14, 18 p., 1143.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

    Hein, J. B. & Nilsson, Jakob, 25 Jan 2014, In: E M B O Reports. 15, p. 264-272

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

    Garvanska, Dimitriya Hristoforova & Nilsson, Jakob, 2020, In: Essays in Biochemistry. 64, 2, p. 325-336

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

    Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    SLiM-binding pockets: an attractive target for broad-spectrum antivirals

    Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    SAC during early cell divisions: Sacrificing fidelity over timely division, regulated differently across organisms Chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varying from species to species

    Duro, Joana Maria & Nilsson, Jakob, 2021, In: BioEssays. 43, 3, 13 p., 2000174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Response to Raaijmakers & Medema

    Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.

    Research output: Contribution to journal › Comment/debate › Research

  24. Published

    Regulation of mitotic progression by the spindle assembly checkpoint

    Lischetti, T. & Nilsson, Jakob, 2015, In: Molecular & Cellular Oncology. 2, 1, e970484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry

    Nasa, I., Cressey, L. E., Kruse, Thomas, Hertz, Emil Peter Thrane, Gui, J., Graves, L. M., Nilsson, Jakob & Kettenbach, A. N., 2020, In: Science Signaling. 13, 648, 15 p., eaba7823.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 8799501