Jakob Nilsson
Professor
Nilsson Group
Blegdamsvej 3B
2200 København N
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Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Zhang, Y., Young, R., Garvanska, Dimitriya Hristoforova, Song, C., Zhai, Y., Wang, Y., Jiang, H., Fang, J., Nilsson, Jakob, Alfieri, C. & Zhang, G., 2024, In: Communications Biology . 7, 12 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
Zhang, G., Lischetti, T., Hayward, D. G. & Nilsson, Jakob, 2 Jun 2015, In: Nature Communications. 6, 14 p., 7162.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to Raaijmakers & Medema
Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.Research output: Contribution to journal › Comment/debate › Research
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The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region
Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In: P L o S One. 8, 4, p. e60596 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex
Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.Research output: Contribution to journal › Journal article › Research › peer-review
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The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores
Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In: Journal of Cell Science. p. 3243-3253 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores
Zhang, G. & Nilsson, Jakob, 2018, In: Cell Cycle. 17, 9, p. 1087-1091Research output: Contribution to journal › Journal article › Research › peer-review
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.Research output: Contribution to journal › Journal article › Research › peer-review
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A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation
Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In: Journal of Cell Science. 127, p. 871-884Research output: Contribution to journal › Journal article › Research › peer-review
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Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In: Nature Communications. 7, p. 1-12 12 p., 12256.Research output: Contribution to journal › Journal article › Research › peer-review
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The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity
Wild, T., Larsen, Marie Sofie Yoo, Narita, Takeo, Schou, J., Nilsson, Jakob & Choudhary, Chunaram, 1 Mar 2016, In: Cell Reports. 14, 8, p. 1829-40 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Y., Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In: eLife. 9, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis
Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption
Vit, G., Hirth, A., Neugebauer, N., Kraft, B. N., Sigismondo, G., Cazzola, A., Tessmer, C., Duro, Joana Maria, Krijgsveld, J., Hofmann, I., Berger, M., Klüter, H., Niehrs, C., Nilsson, Jakob & Krämer, A., 2022, In: Cell Death Discovery. 8, 12 p., 484.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061
Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.Research output: Contribution to journal › Journal article › Research › peer-review
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A Consensus Binding Motif for the PP4 Protein Phosphatase
Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6Research output: Contribution to journal › Journal article › Research › peer-review
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A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis
Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.Research output: Contribution to journal › Journal article › Research › peer-review
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SLiM-binding pockets: an attractive target for broad-spectrum antivirals
Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427Research output: Contribution to journal › Review › Research › peer-review
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Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex
Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In: E M B O Journal. 32, 2, p. 303-314 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis
Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In: Oncogene. 32, 39, p. 4622-4633 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells
Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development
Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, Jens Vilstrup, Hayward, D. G., Nilsson, Jakob, Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, , 2023, In: Nature Communications. 14, 18 p., 1143.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8799501
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
123
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Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Research output: Contribution to journal › Journal article › Research › peer-review
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120
downloads
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Research output: Contribution to journal › Journal article › Research › peer-review
Published