Jakob Nilsson

Jakob Nilsson

Professor

ORCID: 0000-0003-4100-1125

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  1. Published

    Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling

    Zhang, Y., Young, R., Garvanska, Dimitriya Hristoforova, Song, C., Zhai, Y., Wang, Y., Jiang, H., Fang, J., Nilsson, Jakob, Alfieri, C. & Zhang, G., 2024, In: Communications Biology . 7, 12 p., 164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint

    Zhang, G., Lischetti, T., Hayward, D. G. & Nilsson, Jakob, 2 Jun 2015, In: Nature Communications. 6, 14 p., 7162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Response to Raaijmakers & Medema

    Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.

    Research output: Contribution to journal › Comment/debate › Research

  4. Published

    The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region

    Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In: P L o S One. 8, 4, p. e60596 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex

    Zhang, G., Kruse, Thomas, Guasch Boldú, C., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: E M B O Journal. 38, 7, e100977.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores

    Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In: Journal of Cell Science. p. 3243-3253 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

    Zhang, G. & Nilsson, Jakob, 2018, In: Cell Cycle. 17, 9, p. 1087-1091

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

    Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation

    Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In: Journal of Cell Science. 127, p. 871-884

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation

    Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In: Nature Communications. 7, p. 1-12 12 p., 12256.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The Spindle Assembly Checkpoint Is Not Essential for Viability of Human Cells with Genetically Lowered APC/C Activity

    Wild, T., Larsen, Marie Sofie Yoo, Narita, Takeo, Schou, J., Nilsson, Jakob & Choudhary, Chunaram, 1 Mar 2016, In: Cell Reports. 14, 8, p. 1829-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment

    Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Y., Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In: eLife. 9, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

    Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

    Vit, G., Hirth, A., Neugebauer, N., Kraft, B. N., Sigismondo, G., Cazzola, A., Tessmer, C., Duro, Joana Maria, Krijgsveld, J., Hofmann, I., Berger, M., Klüter, H., Niehrs, C., Nilsson, Jakob & Krämer, A., 2022, In: Cell Death Discovery. 8, 12 p., 484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis

    Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    SLiM-binding pockets: an attractive target for broad-spectrum antivirals

    Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling

    Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

    Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In: E M B O Journal. 32, 2, p. 303-314 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

    Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In: Oncogene. 32, 39, p. 4622-4633 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

    Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

    Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

    Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, Jens Vilstrup, Hayward, D. G., Nilsson, Jakob, Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

    Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, Leitner, A. & Westermarck, J., 2023, In: Nature Communications. 14, 18 p., 1143.

    Research output: Contribution to journal › Journal article › Research › peer-review

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