Jakob Nilsson
Professor
Nilsson Group
Blegdamsvej 3B
2200 København N
- 2024
- Published
The NSP3 protein of SARS-CoV-2 binds fragile X mental retardation proteins to disrupt UBAP2L interactions
Garvanska, D. H., Alvarado, R. E., Mundt, F. O., Lindqvist, R., Duel, J. K., Coscia, F., Nilsson, E., Lokugamage, K., Johnson, B. A., Plante, J. A., Morris, D. R., Vu, M. N., Estes, L. K., McLeland, A. M., Walker, J., Crocquet-Valdes, P. A., Mendez, B. L., Plante, K. S., Walker, D. H., Weisser, M. B. & 4 others, , 2024, In: EMBO Reports.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cryo-EM structures of PP2A:B55–FAM122A and PP2A:B55–ARPP19
Padi, S. K. R., Vos, M. R., Godek, R. J., Fuller, J. R., Kruse, Thomas, Hein, J. B., Nilsson, Jakob, Kelker, M. S., Page, R. & Peti, W., 2024, In: Nature. 625, 7993, p. 195-203 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional analysis of Cdc20 reveals a critical role of CRY box in mitotic checkpoint signaling
Zhang, Y., Young, R., Garvanska, Dimitriya Hristoforova, Song, C., Zhai, Y., Wang, Y., Jiang, H., Fang, J., Nilsson, Jakob, Alfieri, C. & Zhang, G., 2024, In: Communications Biology . 7, 12 p., 164.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
Hein, J. B., Nguyen, H. T., Garvanska, Dimitriya Hristoforova, Nasa, I., Kruse, Thomas, Feng, Y., Lopez Mendez, B., Davey, N., Kettenbach, A. N., Fordyce, P. M. & Nilsson, Jakob, 2023, In: Molecular Systems Biology. 19, 17 p., e11782.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The SUMO–NIP45 pathway processes toxic DNA catenanes to prevent mitotic failure
Hertz, Emil Peter Thrane, Alonso de Vega, Ignacio, Kruse, Thomas, Wang, Y., Hendriks, Ivo Alexander, Bizard, A. H., Eugui-Anta, A., Hay, R. T., Nielsen, Michael Lund, Nilsson, Jakob, Hickson, Ian David & Mailand, Niels, 2023, In: Nature Structural and Molecular Biology. 30, p. 1303-1313Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions
Kliche, J., Garvanska, Dimitriya Hristoforova, Simonetti, L., Badgujar, D., Dobritzsch, D., Nilsson, Jakob, Davey, N. E. & Ivarsson, Y., 2023, In: Molecular Systems Biology. 19, 7, 21 p., e11164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A
Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, , 2023, In: Nature Communications. 14, 18 p., 1143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SLiM-binding pockets: an attractive target for broad-spectrum antivirals
Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427Research output: Contribution to journal › Review › Research › peer-review
- Published
Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis
Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061
Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption
Vit, G., Hirth, A., Neugebauer, N., Kraft, B. N., Sigismondo, G., Cazzola, A., Tessmer, C., Duro, Joana Maria, Krijgsveld, J., Hofmann, I., Berger, M., Klüter, H., Niehrs, C., Nilsson, Jakob & Krämer, A., 2022, In: Cell Death Discovery. 8, 12 p., 484.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generation and diversification of recombinant monoclonal antibodies
DeLuca, K. F., Mick, J. E., Ide, A. H., Lima, W. C., Sherman, L., Schaller, K. L., Anderson, S. M., Zhao, N., Stasevich, T. J., Varma, D., Nilsson, Jakob & DeLuca, J. G., 2021, In: eLife. 10, 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SAC during early cell divisions: Sacrificing fidelity over timely division, regulated differently across organisms Chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varying from species to species
Duro, Joana Maria & Nilsson, Jakob, 2021, In: BioEssays. 43, 3, 13 p., 2000174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coupling of Cdc20 inhibition and activation by BubR1
Hein, J. B., Garvanska, Dimitriya Hristoforova, Nasa, I., Kettenbach, A. N. & Nilsson, Jakob, 2021, In: Journal of Cell Biology. 220, 5, e202012081.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities
Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, , 2021, In: Nature Communications. 12, 1, 13 p., 6761.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis
Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions
Garvanska, Dimitriya Hristoforova & Nilsson, Jakob, 2020, In: Essays in Biochemistry. 64, 2, p. 325-336Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Kruse, Thomas, Gnosa, S. P., Nasa, I., Garvanska, Dimitriya Hristoforova, Hein, J. B., Nguyen, H., Samsøe-Petersen, Jacob, Lopez-Mendez, B., Hertz, Emil Peter Thrane, Schwarz, J., Pena, H. S., Nikodemus, D., Kveiborg, Marie, Kettenbach, A. N. & Nilsson, Jakob, 2020, In: EMBO Journal. 39, 18 p., e103695.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry
Nasa, I., Cressey, L. E., Kruse, Thomas, Hertz, Emil Peter Thrane, Gui, J., Graves, L. M., Nilsson, Jakob & Kettenbach, A. N., 2020, In: Science Signaling. 13, 648, 15 p., eaba7823.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Escape from the checkpoint: Nek2A binds a unique conformation of the APC/C-MCC complex
Nilsson, Jakob, 2020, In: EMBO Reports. 21, 6, e50494.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Wang, X., Garvanska, Dimitriya Hristoforova, Nasa, I., Ueki, Y., Zhang, G., Kettenbach, A. N., Peti, W., Nilsson, Jakob & Page, R., 2020, In: eLife. 9, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
The RIF1-PP1 Axis Controls Abscission Timing in Human Cells
Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein phosphatases in the regulation of mitosis
Nilsson, Jakob, 2019, In: The Journal of Cell Biology. 218, 2, 15 p., 395.Research output: Contribution to journal › Review › Research › peer-review
- Published
A Consensus Binding Motif for the PP4 Protein Phosphatase
Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8799501
Most downloads
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185
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
123
downloads
Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
120
downloads
A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Research output: Contribution to journal › Journal article › Research › peer-review
Published