Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor


  1. Published

    XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

    Mortuza, G. B., Cavazza, T., Garcia-Mayoral, M. F., Hermida, D., Peset, I., Pedrero, J. G., Merino, N., Blanco, F. J., Lyngsø, J., Bruix, M., Pedersen, J. S., Vernos, I. & Montoya, Guillermo, 29 Sep 2014, In: Nature Communications. 5, p. 1-12 12 p., 5072.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Visualizing phosphodiester-bond hydrolysis by an endonuclease

    Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, Guillermo, Jan 2015, In: Nature Structural and Molecular Biology. 22, 1, p. 65-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

    Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

    Prieto, J., Redondo, P., López-Méndez, B., D'Abramo, M., Merino, N., Blanco, F. J., Duchateau, P., Montoya, Guillermo & Molina, R., 2018, In: Scientific Reports. 8, p. 1-9 10286.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Transposons and CRISPR: Rewiring Gene Editing

    Tenjo Castano, Francisco Javier, Montoya, Guillermo & Carabias del Rey, Arturo, 2023, In: Biochemistry. 62, 24, p. 3521-3532 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    TnpB structure reveals minimal functional core of Cas12 nuclease family

    Sasnauskas, G., Tamulaitiene, G., Druteika, G., Carabias del Rey, Arturo, Silanskas, A., Kazlauskas, D., Venclovas, Č., Montoya, Guillermo, Karvelis, T. & Siksnys, V., 2023, In: Nature. 616, 7956, p. 384-389 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    The genome editing revolution: A CRISPR-Cas TALE off-target story

    Stella, S. & Montoya, Guillermo, Jul 2016, In: BioEssays. 38, S1, p. S4-S13

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation

    Wang, D. Y., Kamuda, K., Montoya, Guillermo & Mesa, Pablo, 2020, HSF1 and Molecular Chaperones in Biology and Cancer. Mendillo, M. L., Pincus, D. & ScherzShouval, R. (eds.). Springer, p. 21-40 20 p. (Advances in Experimental Medicine and Biology, Vol. 1243).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

    Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

    Sofos, N., Feng, M., Stella, S., Pape, T., Fuglsang, Anders, Lin, Jinzhong, Huang, Q., Li, Y., She, Q. & Montoya, Guillermo, 2020, In: Molecular Cell. 79, 5, p. 741-757

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Structure of the mini-RNA-guided endonuclease CRISPR-Cas12j3

    Carabias del Rey, Arturo, Fuglsang, Anders, Temperini, Piero, Pape, T., Sofos, N., Stella, S., qrc243, qrc243 & Montoya, Guillermo, 2021, In: Nature Communications. 12, 12 p., 4476.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure of the TnsB transposase-DNA complex of type V-K CRISPR-associated transposon

    Tenjo Castano, Francisco Javier, Sofos, N., López-Méndez, B., Stutzke, L. S., Fuglsang, Anders, Stella, S. & Montoya, Guillermo, 2022, In: Nature Communications. 13, 14 p., 5792.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structure of the RAF1-HSP90-CDC37 complex reveals the basis of RAF1 regulation

    García-Alonso, S., Mesa, Pablo, Ovejero, L. D. L. P., Aizpurua, G., Lechuga, C. G., Zarzuela, E., Santiveri, C. M., Sanclemente, M., Muñoz, J., Musteanu, M., Campos-Olivas, R., Martínez-Torrecuadrada, J., Barbacid, M. & Montoya, Guillermo, 2022, In: Molecular Cell. 82, 18, p. 3438-3452.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Structure of the I-SceI nuclease complexed with its dsDNA target and three catalytic metal ions

    Prieto, J., Redondo, P., Merino, N., Villate, M., Montoya, Guillermo, Blanco, F. J. & Molina, R., Jun 2016, In: Acta crystallographica. Section F, Structural biology communications. 72, Pt 6, p. 473-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

    Stella, S., Alcón, P. & Montoya, Guillermo, 22 Jun 2017, In: Nature. 546, 7659, p. 559-563 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  16. Structure of the AvrBs3-DNA complex provides new insights into the initial thymine-recognition mechanism

    Stella, S., Molina, R., Yefimenko, I., Prieto, J., Silva, G., Bertonati, C., Juillerat, A., Duchateau, P. & Montoya, Guillermo, 2013, In: Acta Crystallographica Section D: Biological Crystallography. 69, 9, p. 1707-1716 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Structure of p15PAF-PCNA complex and implications for clamp sliding during DNA replication and repair

    De Biasio, A., de Opakua, A. I., Mortuza, G. B., Molina, R., Cordeiro, T. N., Castillo, F., Villate, M., Merino, N., Delgado, S., Gil-Cartón, D., Luque, I., Diercks, T., Bernadó, P., Montoya, Guillermo & Blanco, F. J., 12 Mar 2015, In: Nature Communications. 6, p. 1-12 6439.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

    Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

    Alba, J., Marcaida, M. J., Prieto, J., Montoya, Guillermo, Molina, R. & D'Abramo, M., Dec 2017, In: Journal of Computer - Aided Molecular Design. 31, 12, p. 1063-1072 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases

    Molina Monterrubio, R. A., Jensen, A. L. G., Marchena-Hurtado, J., López-Méndez, B., Stella, S. & Montoya, Guillermo, 2021, In: Nucleic Acids Research. 49, 21, p. 12577-12590 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Structural basis of CRISPR-Cas Type III prokaryotic defence systems

    Molina, R., Sofos, N. & Montoya, Guillermo, 2020, In: Current Opinion in Structural Biology. 65, p. 119-129 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published
  23. Published

    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

    Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Non-specific protein-DNA interactions control I-CreI target binding and cleavage

    Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Molecular scissors for in situ cellular repair

    Prieto, J., Molina, R. & Montoya, Guillermo, 31 Jan 2012, In: Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

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ID: 93716435