Julien Duxin

Julien Duxin

Associate Professor - Promotion Programme, Ekstern forsker

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    ORCID: 0000-0001-9389-4186

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    1. Published

      A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene

      Gao, Y., Guitton-Sert, L., Dessapt, J., Coulombe, Y., Rodrigue, A., Milano, L., Blondeau, A., Larsen, N. B., Duxin, Julien, Hussein, S., Fradet-Turcotte, A. & Masson, J. Y., 2023, In: Nature Communications. 14, 1, 20 p., 381.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

      Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      A safe fix for alcohol-derived DNA damage: [Alcohol-derived DNA damage fixed in two ways]

      Gallina, I. & Duxin, Julien, 2020, In: Nature. 579, 7800, p. 499-500 2 p.

      Research output: Contribution to journal › Comment/debate › Research

    4. Published

      Crosstalk between repair pathways elicits Double Strand Breaks in alkylated DNA and implications for the action of temozolomide

      Fuchs, R. P., Isogawa, A., Paulo, J. A., Onizuka, K., Takahashi, T., Amunugama, R., Duxin, Julien & Fujii, S., 2021, In: eLife. 10, 21 p., e69544.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network

      Karanja, K. K., Cox, S. W., Duxin, Julien, Stewart, S. A. & Campbell, J. L., 1 Nov 2012, In: Cell Cycle. 11, 21, p. 3983-96 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

      Kose, H. B., Larsen, N. B., Duxin, Julien & Yardimci, H., 2019, In: Cell Reports. 26, 8, p. 2113-2125.e6 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. FEN1 ensures telomere stability by facilitating replication fork re-initiation

      Saharia, A., Teasley, D. C., Duxin, Julien, Dao, B., Chiappinelli, K. B. & Stewart, S. A., 27 Aug 2010, In: The Journal of Biological Chemistry. 285, 35, p. 27057-66 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      How to fix DNA-protein crosslinks

      Kühbacher, U. & Duxin, Julien, 2020, In: DNA Repair. 94, 14 p., 102924.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

      Duxin, Julien, Dao, B., Martinsson, P., Rajala, N., Guittat, L., Campbell, J. L., Spelbrink, J. N. & Stewart, S. A., Aug 2009, In: Molecular and Cellular Biology. 29, 15, p. 4274-82 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway

      Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

      Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.

      Research output: Working paper › Preprint

    12. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication

      Duxin, Julien, Moore, H. R., Sidorova, J., Karanja, K. K., Honaker, Y., Dao, B., Piwnica-Worms, H., Campbell, J. L., Monnat, R. J. & Stewart, S. A., 22 Jun 2012, In: The Journal of Biological Chemistry. 287, 26, p. 21980-91 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1

      S.Colding-Christensen, Camilla, Kakulidis, Ellen Sofia, Arroyo Gomez, Javier, Hendriks, Ivo Alexander, Arkinson, C., Fábián, Z., Gambus, A., Mailand, Niels, Duxin, Julien & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 19 p., 8293.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Repair of a DNA-protein crosslink by replication-coupled proteolysis

      Duxin, Julien, Dewar, J. M., Yardimci, H. & Walter, J. C., 9 Oct 2014, In: Cell. 159, 2, p. 346-57 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

      Larsen, N. B., Gao, A. O., Sparks, J. L., Gallina, I., Wu, R. A., Mann, Matthias, Räschle, M., Walter, J. C. & Duxin, Julien, 2019, In: Molecular Cell. 73, 3, p. 574-588.e7 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS

      Nittis, T., Guittat, L., LeDuc, R. D., Dao, B., Duxin, Julien, Rohrs, H., Townsend, R. R. & Stewart, S. A., Jun 2010, In: Molecular and Cellular Proteomics. 9, 6, p. 1144-56 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

      Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Targeting DNA-Protein Crosslinks via Post-Translational Modifications

      Leng, Xueyuan & Duxin, Julien, 2022, In: Frontiers in Molecular Biosciences. 9, 14 p., 944775.

      Research output: Contribution to journal › Review › Research › peer-review

    19. Published

      The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

      Sparks, J. L., Chistol, G., Gao, A. O., Räschle, M., Larsen, N. B., Mann, Matthias, Duxin, Julien & Walter, J. C., 2019, In: Cell. 176, 1-2, p. 167-181.e21

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

      Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

      Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      What are the DNA lesions underlying formaldehyde toxicity?

      Benedict, Bente, Kristensen, S. M. & Duxin, Julien, 2024, In: DNA Repair. 138, 14 p., 103667.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. What is the DNA repair defect underlying Fanconi anemia?

      Duxin, Julien & Walter, J. C., Dec 2015, In: Current Opinion in Cell Biology. 37, p. 49-60 12 p.

      Research output: Contribution to journal › Review › Research › peer-review

    ID: 164085189