Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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SPIN enables high throughput species identification of archaeological bone by proteomics
Rüther, P. L., Husic, I. M., Bangsgaard, Pernille, Gregersen, K. M., Pantmann, P., Carvalho, M., Godinho, R. M., Friedl, L., Cascalheira, J., Taurozzi, Alberto John, Jørkov, M L S, Benedetti, M. M., Haws, J., Bicho, N., Welker, Frido, Cappellini, Enrico & Olsen, Jesper Velgaard, 2022, In: Nature Communications. 13, 14 p., 2458.Research output: Contribution to journal › Journal article › Research › peer-review
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ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping
Samodova, D., Hosfield, C. M., Cramer, C. N., Giuli, M. V., Cappellini, Enrico, Franciosa, Giulia, Rosenblatt, M. M., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2020, In: Molecular & Cellular Proteomics. 19, 12, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action
Sampadi, B., Pines, A., Munk, S., Mišovic, B., de Groot, A. J., van de Water, B., Olsen, Jesper Velgaard, Mullenders, L. H. F. & Vrieling, H., 2020, In: Archives of Toxicology. 94, p. 1655-1671 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation
Sampadi, B., Vermeulen, S., Mišovic, B., Boei, J. J., Batth, Tanveer Singh, Chang, J. G., Paulsen, M. T., Magnuson, B., Schimmel, J., Kool, H., Olie, C. S., Everts, B., Vertegaal, A. C. O., Olsen, Jesper Velgaard, Ljungman, M., Jeggo, P. A., Mullenders, L. H. F. & Vrieling, H., 2022, In: Cells. 11, 23, 25 p., 3794.Research output: Contribution to journal › Journal article › Research › peer-review
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Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor
Sanchez-Quiles, V., Akimov, V., Osinalde, N., Francavilla, C., Puglia, M., Barrio-Hernandez, I., Kratchmarova, I., Olsen, Jesper Velgaard & Blagoev, B., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1433-1446 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic profiling of archaeological human bone
Sawafuji, R., Cappellini, Enrico, Nagaoka, T., Fotaki, Anna Katerina, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Hirata, K. & Ueda, S., Jun 2017, In: Royal Society Open Science. 4, 6, 12 p., 161004.Research output: Contribution to journal › Journal article › Research › peer-review
A mass spectrometry-friendly database for cSNP identification
Schandorff, S., Olsen, Jesper Velgaard, Bunkenborg, J., Blagoev, B., Zhang, Y., Andersen, J. S. & Mann, Matthias, 2007, In: Nature Methods. 4, 6, p. 465-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein
Schimmel, J., Eifler, K., Sigurdsson, J. O., Cuijpers, S. A. G., Hendriks, I. A., Verlaan-de Vries, M., Kelstrup, C. D., Francavilla, C., Medema, R. H., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 20 Mar 2014, In: Molecular Cell. 53, 6, p. 1053-1066Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of animal species in skin clothing from museum collections
Schmidt, A. L., Gilbert, M Thomas P, Cappellini, Enrico & Olsen, Jesper Velgaard, 2011. 8 p.Research output: Contribution to conference › Paper › Research › peer-review
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Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient biomolecules reveal ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from Sicily
Scorrano, Gabriele, Nielsen, S. H., Lo Vetro, D., Mackie, Meaghan, Fabbri, P. F., Allentoft, Morten Erik, Martini, F., Martanez-Labarga, C., Rickards, O., Olsen, Jesper Velgaard, Willerslev, Eske, Cappellini, Enrico & Sikora, Martin, 2020, p. 255-255.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Scorrano, Gabriele, Nielsen, Sofie Holtsmark, Vetro, D. L., Sawafuji, R., Mackie, Meaghan, Margaryan, Ashot, Fotaki, Anna Katerina, Martínez-Labarga, C., Fabbri, P. F., Allentoft, Morten Erik, Carra, M., Martini, F., Rickards, O., Olsen, Jesper Velgaard, Pedersen, Mikkel Winther, Cappellini, Enrico & Sikora, Martin, 2022, In: Communications Biology. 5Research output: Contribution to journal › Journal article › Research › peer-review
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Analytic framework for peptidomics applied to large-scale neuropeptide identification
Secher, A., Kelstrup, C. D., Conde-Frieboes, K. W., Pyke, C., Raun, K., Wulff, B. S. & Olsen, Jesper Velgaard, 2016, In: Nature Communications. 7, 10 p., 11436.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomics strategy for quantitative protein interaction profiling in cell extracts
Sharma, K., Weber, C., Bairlein, M., Greff, Z., Kéri, G., Cox, J., Olsen, Jesper Velgaard & Daub, H., 2009, In: Nature Methods. 6, 10, p. 741-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
In-gel digestion for mass spectrometric characterization of proteins and proteomes
Shevchenko, A., Tomas, H., Havlis, J., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Nature Protocols (Print Edition). 1, 6, p. 2856-60 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
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Global analysis of the yeast osmotic stress response by quantitative proteomics
Soufi, B., Kelstrup, C. D., Stoehr, G., Fröhlich, F., Walther, T. C. & Olsen, Jesper Velgaard, 2009, In: Molecular BioSystems. 5, 11, p. 1337-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structures of down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition
Soundararajan, M., Roos, A. K., Savitsky, P., Filippakopoulos, P., Kettenbach, A. N., Olsen, Jesper Velgaard, Gerber, S., Eswaran, J., Knapp, S. & Elkins, J. M., 4 Jun 2013, In: Structure. 21, 6, p. 986-996 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PKD Phosphorylation as Novel Pathway of KV11.1 Regulation
Steffensen, Annette Buur, Bomholtz, Sofia Hammami, Andersen, M. N., Olsen, Jesper Velgaard, Mutsaers, N., Lundegaard, Pia Rengtved, Lundby, Alicia & Schmitt, Nicole, 2018, In: Cellular Physiology and Biochemistry. 47, 4, p. 1742-1750 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Electron capture dissociation of singly and multiply phosphorylated peptides
Stensballe, A., Jensen, O. N., Olsen, Jesper Velgaard, Haselmann, K. F. & Zubarev, R. A., 2000, In: Rapid Communications in Mass Spectrometry. 14, 19, p. 1793-800 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of Changes in SUMO-2/3 Modification during Breast Cancer Progression and Metastasis
Subramonian, D., Raghunayakula, S., Olsen, Jesper Velgaard, Beningo, K. A., Paschen, W. & Zhang, X., Sep 2014, In: Journal of Proteome Research. 13, 9, p. 3905–3918 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner
Sun, J., Mohlin, S., Lundby, Alicia, Kazi, J. U., Hellman, U., Påhlman, S., Olsen, Jesper Velgaard & Rönnstrand, L., 11 Nov 2013, In: Oncogene.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel
Taurozzi, Alberto John, Rüther, P. L., Patramanis, Ioannis, Koenig, Claire, Paterson, Ryan Sinclair, Madupe, Palesa Petunia, Harking, F. S., Welker, Frido, Mackie, Meaghan, Ramos Madrigal, Jazmin, Olsen, Jesper Velgaard & Cappellini, Enrico, 2024, (E-pub ahead of print) In: Nature Protocols. 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The SH2 domain interaction landscape
Tinti, M., Kiemer, L., Costa, S., Miller, M. L., Sacco, F., Olsen, Jesper Velgaard, Carducci, M., Paoluzi, S., Langone, F., Workman, C., Blom, N., Machida, K., Thompson, C. M., Schutkowski, M., Brunak, Søren, Mann, Matthias, Mayer, B. J., Castagnoli, L. & Cesareni, G., 2013, In: Cell Reports. 3, 4, p. 1293-1305 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling
Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extending the Coverage of Lys-C/Trypsin-Based Bottom-up Proteomics by Cysteine S-Aminoethylation
Tomioka, R., Tomioka, A., Ogata, K., Chan, H. J., Chen, L. Y., Hernández Guzmán, Ulises, Xuan, Y., Olsen, Jesper Velgaard, Chen, Y. J. & Ishihama, Y., 2024, In: Journal of the American Society for Mass Spectrometry. 35, 2, p. 386-396 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alternative Translation Initiation Generates a Functionally Distinct Isoform of the Stress-Activated Protein Kinase MK2
Trulley, P., Snieckute, Goda, Bekker-Jensen, D., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2019, In: Cell Reports. 27, 10, p. 2859-2870.e6 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2
Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).Research output: Working paper › Preprint
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Palaeoproteomic identification of breast milk protein residues from the archaeological skeletal remains of a neonatal dog
Tsutaya, T., Mackie, Meaghan, Koenig, C., Sato, T., Weber, A. W., Kato, H., Olsen, Jesper Velgaard & Cappellini, Enrico, 2019, In: Scientific Reports. 9, 7 p., 12841.Research output: Contribution to journal › Journal article › Research › peer-review
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Faecal proteomics as a novel method to study mammalian behaviour and physiology
Tsutaya, T., Mackie, Meaghan, Sawafuji, R., Miyabe-Nishiwaki, T., Olsen, Jesper Velgaard & Cappellini, Enrico, 2021, In: Molecular Ecology Resources. 21, 6, p. 1808-1819 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphorylation Variation during the Cell Cycle Scales with Structural Propensities of Proteins
Tyanova, S., Frishman, D., Cox, J., Mann, Matthias & Olsen, Jesper Velgaard, 10 Jan 2013, In: P L o S Computational Biology (Online). 9, 1, p. e1002842 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and proteomic evidence for Mycobacterium leprae in human medieval dental calculus from Trondheim, Norway
Vagene, A. J., Fotaki, Anna Katerina, Denham, S. D., Orbegozo, M., Mackie, Meaghan, Olsen, Jesper Velgaard, Cappellini, Enrico, Christophersen, A. & Gilbert, M Thomas P, 2020, In: American Journal of Physical Anthropology. 171, p. 291 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers
Vermeulen, M., Eberl, H. C., Matarese, F., Marks, H., Denissov, S., Butter, F., Lee, K. K., Olsen, Jesper Velgaard, Hyman, A. A., Stunnenberg, H. G. & Mann, M., 17 Sep 2010, In: Cell. 142, 6, p. 967-80 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
Vind, Anna Constance, Snieckute, Goda, Blasius, Melanie, Tiedje, C., Krogh, Nicolai, Bekker-Jensen, D. B., Andersen, Kasper Langebjerg, Nordgaard, C., Tollenaere, M. A. X., Lund, Anders H., Olsen, Jesper Velgaard, Nielsen, Henrik & Bekker-Jensen, Simon Holst, 2020, In: Molecular Cell. 78, 4, p. 700-713.E7Research output: Contribution to journal › Journal article › Research › peer-review
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RNF4 is required for DNA double-strand break repair in vivo
Vyas, R., Kumar, R., Clermont, F., Helfricht, A., Kalev, P., Sotiropoulou, P., Hendriks, I. A., Radaelli, E., Hochepied, T., Blanpain, C., Sablina, A., van Attikum, H., Olsen, Jesper Velgaard, Jochemsen, A. G., Vertegaal, A. C. O. & Marine, J., Mar 2013, In: Cell Death and Differentiation. 20, 3, p. 490-502 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues
Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.Research output: Contribution to journal › Journal article › Research › peer-review
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Yeast expression proteomics by high-resolution mass spectrometry
Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2010, In: Methods in Enzymology. 470, p. 259-80 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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qcML: an exchange format for quality control metrics from mass spectrometry experiments
Walzer, M., Pernas, L. E., Nasso, S., Bittremieux, W., Nahnsen, S., Kelchtermans, P., Pichler, P., van den Toorn, H. W. P., Staes, A., Vandenbussche, J., Mazanek, M., Taus, T., Scheltema, R. A., Kelstrup, C. D., Gatto, L., van Breukelen, B., Aiche, S., Valkenborg, D., Laukens, K., Lilley, K. S. & 9 others, , 23 Apr 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1905-1913 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O. E., Swallow, D. M., Fotakis, A. K., Jersie-Christensen, R. R., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Charlton, S., Mackie, M. E., Canci, A., Bouwman, A. & 3 others, , 2014, In: Scientific Reports. 4, 6 p., 7104.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathogens and host immunity in the ancient human oral cavity
Warinner, C., Rodrigues, J. F. M., Vyas, R., Trachsel, C., Shved, N., Grossmann, J., Radini, A., Hancock, Y., Tito, R. Y., Fiddyment, S., Speller, C., Hendy, J., Charlton, S., Luder, H. U., Salazar-García, D. C., Eppler, E., Seiler, R., Hansen, L. H., Samaniego Castruita, J. A., Barkow-Oesterreicher, S. & 12 others, , 2014, In: Nature Genetics. 46, p. 336-344 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O., Swallow, D. M., Fotakis, A. K., Christensen, R. J., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Mackie, M., Canci, A., Bouwman, A., Ruhli, F. & 2 others, , 2015, In: American Journal of Physical Anthropology. 156, Suppl. 60, p. 319 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Atypical cofilin signaling drives dendritic cell migration through the extracellular matrix via nuclear deformation
Warner, H., Franciosa, Giulia, van der Borg, G., Coenen, B., Faas, Felix, Koenig, Claire, de Boer, R., Classens, R., Maassen, S., Baranov, M. V., Mahajan, S., Dabral, D., Bianchi, F., van Hilten, N., Risselada, H. J., Roos, W. H., Olsen, Jesper Velgaard, Cano, L. Q. & van den Bogaart, G., 2024, In: Cell Reports. 43, 3, 28 p., 113866.Research output: Contribution to journal › Journal article › Research › peer-review
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Pre-Clovis mastodon hunting 13,800 years ago at the Manis site, Washington
Waters, M. R., Stafford jr., T., McDonald, H. G., Gustafson, C., Rasmussen, M., Cappellini, Enrico, Olsen, Jesper Velgaard, Szklarczyk, D. M., Jensen, Lars Juhl, Gilbert, M Thomas P & Willerslev, Eske, 2011, In: Science. 334, 6054, p. 351-353 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation
Weinert, B. T., Wagner, S. A., Horn, H., Henriksen, P., Liu, W. R., Olsen, Jesper Velgaard, Jensen, Lars Juhl & Choudhary, Chunaram, 2011, In: Science Signaling. 4, 183, p. ra48Research output: Contribution to journal › Journal article › Research › peer-review
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The phosphoproteome of toll-like receptor-activated macrophages
Weintz, G., Olsen, Jesper Velgaard, Frühauf, K., Niedzielska, M., Amit, I., Jantsch, J., Mages, J., Frech, C., Dölken, L., Mann, M. & Lang, R., 8 Jun 2010, In: Molecular Systems Biology. 6, p. 371Research output: Contribution to journal › Journal article › Research › peer-review
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Enamel proteome shows that Gigantopithecus was an early diverging pongine
Welker, Frido, Ramos Madrigal, Jazmin, Kuhlwilm, M., Liao, W., Gutenbrunner, P., de Manuel, M., Samodova, D., Mackie, Meaghan, Allentoft, Morten Erik, Bacon, A., Collins, Matthew James, Cox, J., Lalueza-Fox, C., Olsen, Jesper Velgaard, Demeter, Fabrice, Wang, W., Marques-Bonet, T. & Cappellini, Enrico, 2019, In: Nature. 576, p. 262-265Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient proteins resolve the evolutionary history of Darwin's South American ungulates
Welker, F., Collins, M. J., Thomas, J. A., Wadsley, M., Brace, S., Cappellini, E., Turvey, S. T., Reguero, M., Gelfo, J. N., Kramarz, A., Burger, J., Thomas-Oates, J., Ashford, D. A., Ashton, P. D., Rowsell, K., Porter, D. M., Kessler, B., Fischer, R., Baessmann, C., Kaspar, S. & 11 others, , 4 Jun 2015, In: Nature. 522, 7554, p. 81–84 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Palaeoproteomic analysis of Early Pleistocene Gigantopithecus blacki
Welker, Frido, Ramos Madrigal, Jazmin, Wang, W., Kuhlwilm, M., Montero, M. D. M., Demeter, Fabrice, Lalueza-Fox, C., Marques-Bonet, T., Olsen, Jesper Velgaard & Cappellini, Enrico, Mar 2019, In: American Journal of Physical Anthropology. 168, suppl. 68, p. 265-266Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 9925376
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Molecular basis of Tousled-Like Kinase 2 activation
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52 Genetic Loci Influencing Myocardial Mass
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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