Platelet storage and functional integrity

Research output: Contribution to journal › Review › Research › peer-review

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Platelet storage and functional integrity. / Vit, Gianmatteo; Kluter, Harald; Wuchter, Patrick.

In: Journal of Laboratory Medicine, Vol. 44, No. 5, 2020, p. 285-293.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Vit, G, Kluter, H & Wuchter, P 2020, 'Platelet storage and functional integrity', Journal of Laboratory Medicine, vol. 44, no. 5, pp. 285-293. https://doi.org/10.1515/labmed-2020-0067

APA

Vit, G., Kluter, H., & Wuchter, P. (2020). Platelet storage and functional integrity. Journal of Laboratory Medicine, 44(5), 285-293. https://doi.org/10.1515/labmed-2020-0067

Vancouver

Vit G, Kluter H, Wuchter P. Platelet storage and functional integrity. Journal of Laboratory Medicine. 2020;44(5):285-293. https://doi.org/10.1515/labmed-2020-0067

Author

Vit, Gianmatteo ; Kluter, Harald ; Wuchter, Patrick. / Platelet storage and functional integrity. In: Journal of Laboratory Medicine. 2020 ; Vol. 44, No. 5. pp. 285-293.

Bibtex

@article{623f8db33c14437296100df50f77d6be,
title = "Platelet storage and functional integrity",
abstract = "Platelet transfusion is a topic of common interest for many specialists involved in patient care, from laboratory staff to clinical physicians. Various aspects make this type of transfusion different from those of other blood components. In this review, the challenges in platelet transfusion practice that are relevant for laboratory colleagues will be discussed, highlighting how the biochemical and structural characteristics of these blood elements directly affect their function and consequently the clinical outcome. More than 1,300 platelet concentrates are transfused in Germany every day, and several types are offered by their respective manufacturers. We describe the technological advances in platelet concentrate production, with a focus on how the storage conditions of platelets can be improved. Laboratory quality assessment procedures for a safe transfusion are discussed in detail. For this purpose, we will refer to the Hemotherapy Directives (Richtlinie Hamotherapie) of the German Medical Association.",
keywords = "platelet concentrate, thrombocytopenia, transfusion, POLYMERASE-CHAIN-REACTION, BACTERIAL-CONTAMINATION, ARACHIDONIC-ACID, P-SELECTIN, IN-VITRO, APHERESIS, ACTIVATION, COLD, IMPLEMENTATION, IDENTIFICATION",
author = "Gianmatteo Vit and Harald Kluter and Patrick Wuchter",
year = "2020",
doi = "10.1515/labmed-2020-0067",
language = "English",
volume = "44",
pages = "285--293",
journal = "Journal of Laboratory Medicine",
issn = "2567-9430",
publisher = "De Gruyter",
number = "5",

}

RIS

TY - JOUR

T1 - Platelet storage and functional integrity

AU - Vit, Gianmatteo

AU - Kluter, Harald

AU - Wuchter, Patrick

PY - 2020

Y1 - 2020

N2 - Platelet transfusion is a topic of common interest for many specialists involved in patient care, from laboratory staff to clinical physicians. Various aspects make this type of transfusion different from those of other blood components. In this review, the challenges in platelet transfusion practice that are relevant for laboratory colleagues will be discussed, highlighting how the biochemical and structural characteristics of these blood elements directly affect their function and consequently the clinical outcome. More than 1,300 platelet concentrates are transfused in Germany every day, and several types are offered by their respective manufacturers. We describe the technological advances in platelet concentrate production, with a focus on how the storage conditions of platelets can be improved. Laboratory quality assessment procedures for a safe transfusion are discussed in detail. For this purpose, we will refer to the Hemotherapy Directives (Richtlinie Hamotherapie) of the German Medical Association.

AB - Platelet transfusion is a topic of common interest for many specialists involved in patient care, from laboratory staff to clinical physicians. Various aspects make this type of transfusion different from those of other blood components. In this review, the challenges in platelet transfusion practice that are relevant for laboratory colleagues will be discussed, highlighting how the biochemical and structural characteristics of these blood elements directly affect their function and consequently the clinical outcome. More than 1,300 platelet concentrates are transfused in Germany every day, and several types are offered by their respective manufacturers. We describe the technological advances in platelet concentrate production, with a focus on how the storage conditions of platelets can be improved. Laboratory quality assessment procedures for a safe transfusion are discussed in detail. For this purpose, we will refer to the Hemotherapy Directives (Richtlinie Hamotherapie) of the German Medical Association.

KW - platelet concentrate

KW - thrombocytopenia

KW - transfusion

KW - POLYMERASE-CHAIN-REACTION

KW - BACTERIAL-CONTAMINATION

KW - ARACHIDONIC-ACID

KW - P-SELECTIN

KW - IN-VITRO

KW - APHERESIS

KW - ACTIVATION

KW - COLD

KW - IMPLEMENTATION

KW - IDENTIFICATION

U2 - 10.1515/labmed-2020-0067

DO - 10.1515/labmed-2020-0067

M3 - Review

VL - 44

SP - 285

EP - 293

JO - Journal of Laboratory Medicine

JF - Journal of Laboratory Medicine

SN - 2567-9430

IS - 5

ER -

ID: 251311345