Matthias Mann
Professor, head of research, Professor
- E-pub ahead of print
Comparative quantitative proteomic analysis of melanoma subtypes, nevus-associated melanoma, and corresponding nevi
Naimy, S., Sølberg, J. B. K., Kuczek, D. E., Løvendorf, Marianne Bengtson, Bzorek, M., Litman, Thomas, Mund, Andreas, Gjerdrum, Lise Mette Rahbek, Clark, R. A., Mann, Matthias & Dyring-Andersen, Beatrice, 5 Jan 2024, (E-pub ahead of print) In: The Journal of Investigative Dermatology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Correction to Feasibility of Large-Scale Phosphoproteomics with Higher Energy Collisional Dissociation Fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, Matthias, 2012, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
Unique ligand and kinase-independent roles of the insulin receptor in regulation of cell cycle, senescence and apoptosis
Nagao, H., Jayavelu, A. K., Cai, W., Pan, H., Dreyfuss, J. M., Batista, T. M., Brandão, B. B., Mann, Matthias & Kahn, C. R., 4 Jan 2023, In: Nature Communications. 14, 1, p. 57Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains
Nagao, H., Cai, W., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Batista, T. M., Pan, H., Dreyfuss, J. M., Mann, Matthias & Kahn, C. R., 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 17, e2019474118.Research output: Contribution to journal › Journal article › Research › peer-review
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Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling
Nagao, H., Cai, W., Brandão, B. B., Albrechtsen, Nicolai Jacob Wewer, Steger, M., Gattu, A. K., Pan, H., Dreyfuss, J. M., Thomas Wunderlich, F., Mann, Matthias & Ronald Kahn, C., 2023, In: Journal of Clinical Investigation. 133, 4, 18 p., e161472.Research output: Contribution to journal › Journal article › Research › peer-review
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A new parallel high-pressure packing system enables rapid multiplexed production of capillary columns
Müller-Reif, J. B., Hansen, F. M., Schweizer, L., Treit, P. V., Geyer, P. E. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 10 p., 100082.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The proteome landscape of the kingdoms of life
Müller, J. B., Geyer, P. E., Colaço, A. R., Treit, P. V., Strauss, M. T., Oroshi, M., Doll, S., Virreira Winter, S., Bader, J. M., Köhler, N., Theis, F., Santos, A. & Mann, Matthias, 2020, In: Nature. 582, p. 592-596Research output: Contribution to journal › Journal article › Research › peer-review
Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging
Murgia, M., Toniolo, L., Nagaraj, N., Ciciliot, S., Vindigni, V., Schiaffino, S., Reggiani, C. & Mann, Matthias, 13 Jun 2017, In: Cell Reports. 19, 11, p. 2396-2409 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics of Cytochrome c Oxidase-Negative versus -Positive Muscle Fiber Sections in Mitochondrial Myopathy
Murgia, M., Tan, J., Geyer, P. E., Doll, S., Mann, Matthias & Klopstock, T., 2019, In: Cell Reports. 29, 12, p. 3825-3834 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protein profile of fiber types in human skeletal muscle: a single-fiber proteomics study
Murgia, M., Nogara, L., Baraldo, M., Reggiani, C., Mann, Matthias & Schiaffino, S., 2021, In: Skeletal Muscle. 11, 1, 19 p., 24.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma proteome profiling of healthy subjects undergoing bed rest reveals unloading-dependent changes linked to muscle atrophy
Murgia, M., Brocca, L., Monti, E., Franchi, M. V., Zwiebel, M., Steigerwald, S., Giacomello, E., Sartori, R., Zampieri, S., Capovilla, G., Gasparini, M., Biolo, G., Sandri, M., Mann, Matthias & Narici, M. V., 2023, In: Journal of Cachexia, Sarcopenia and Muscle. 14, p. 439-451Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single muscle fiber proteomics reveals unexpected mitochondrial specialization
Murgia, M., Nagaraj, N., Deshmukh, Atul Shahaji, Zeiler, M., Cancellara, P., Moretti, I., Reggiani, C., Schiaffino, S. & Mann, Matthias, 1 Mar 2015, In: E M B O Reports. 16, 3, p. 387-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foresight in clinical proteomics: current status, ethical considerations, and future perspectives
Mundt Madsen, Filip Oskar, Albrechtsen, Nicolai Jacob Wewer, Porsdam Mann, Sebastian, Treit, P., Ghodgaonkar-Steger, M., O’Flaherty, M., Raijmakers, R., Vizcaíno, J. A., Heck, A. J. R. & Mann, Matthias, 2023, In: Open Research Europe. 3, 19 p., 59.Research output: Contribution to journal › Letter › Research › peer-review
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Spatial characterization of single tumor cells by proteomics
Mund, Andreas & Mann, Matthias, 2022, In: Nature Biotechnology. 40, 8, p. 1186-1187 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Unbiased spatial proteomics with single-cell resolution in tissues
Mund, Andreas, Brunner, A. & Mann, Matthias, 2022, In: Molecular Cell. 82, 12, p. 2335-2349 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Deep Visual Proteomics defines single-cell identity and heterogeneity
Mund, A., Coscia, F., Kriston, A., Hollandi, R., Kovács, F., Brunner, A-D., Migh, E., Schweizer, L., Santos, A., Bzorek, M., Naimy, S., Rahbek-Gjerdrum, L. M., Dyring-Andersen, B., Bulkescher, J., Lukas, C., Eckert, M. A., Lengyel, E., Gnann, C., Lundberg, E., Horvath, P. & 1 others, , 2022, In: Nature Biotechnology. 40, p. 1231-1240Research output: Contribution to journal › Journal article › Research › peer-review
MSQuant, an Open Source Platform for Mass Spectrometry-Based Quantitative Proteomics
Mortensen, P., Gouw, J. W., Olsen, Jesper Velgaard, Ong, S., Rigbolt, K. T. G., Bunkenborg, J., Cox, J., Foster, L. J., Heck, A. J. R., Blagoev, B., Andersen, J. S. & Mann, Matthias, Jan 2010, In: Journal of Proteome Research.Research output: Contribution to journal › Journal article › Research › peer-review
Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria
Mootha, V. K., Bunkenborg, J., Olsen, Jesper Velgaard, Hjerrild, M., Wisniewski, J. R., Stahl, E., Bolouri, M. S., Ray, H. N., Sihag, S., Kamal, M., Patterson, N., Lander, E. S. & Mann, Matthias, 2003, In: Cell. 115, 5, p. 629-40 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data
Mischnik, M., Sacco, F., Cox, J., Schneider, H., Schäfer, M., Hendlich, M., Crowther, D., Mann, Matthias & Klabunde, T., 1 Feb 2016, In: Bioinformatics (Online). 32, 3, p. 424-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
HYPK promotes the activity of the Nα-acetyltransferase A complex to determine proteostasis of nonAc-X2/N-degron-containing proteins
Miklánková, P., Linster, E., Boyer, J., Weidenhausen, J., Mueller, J., Armbruster, L., Lapouge, K., De La Torre, C., Bienvenut, W., Sticht, C., Mann, Matthias, Meinnel, T., Sinning, I., Giglione, C., Hell, R. & Wirtz, M., 2022, In: Science Advances. 8, 24, 14 p., eabn6153.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The social and structural architecture of the yeast protein interactome
Michaelis, A. C., Brunner, A., Zwiebel, M., Meier, F., Strauss, Maximilian, Bludau, I. & Mann, Matthias, 2023, In: Nature. 624, 7990, p. 192-200 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The emerging role of mass spectrometry-based proteomics in drug discovery
Meissner, F., Geddes-McAlister, J., Mann, Matthias & Bantscheff, M., 2022, In: Nature Reviews Drug Discovery. 21, p. 637-654 18 p.Research output: Contribution to journal › Review › Research › peer-review
Direct proteomic quantification of the secretome of activated immune cells
Meissner, F., Scheltema, R. A., Mollenkopf, H. & Mann, Matthias, 26 Apr 2013, In: Science (New York, N.Y.). 340, 6131, p. 475-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BoxCar acquisition method enables single-shot proteomics at a depth of 10,000 proteins in 100 minutes
Meier, F., Geyer, P. E., Virreira Winter, S., Cox, J. & Mann, Matthias, 2018, In: Nature Methods. 15, 6, p. 440-448 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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diaPASEF: parallel accumulation-serial fragmentation combined with data-independent acquisition
Meier, F., Brunner, A., Frank, M., Ha, A., Bludau, I., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Bache, N., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2020, In: Nature Methods. 17, 12, p. 1229-1236Research output: Contribution to journal › Journal article › Research › peer-review
Deep learning the collisional cross sections of the peptide universe from a million experimental values
Meier, F., Köhler, N. D., Brunner, A. D., Wanka, J. M. H., Voytik, E., Strauss, M. T., Theis, F. J. & Mann, Matthias, 2021, In: Nature Communications. 12, 12 p., 1185.Research output: Contribution to journal › Journal article › Research › peer-review
Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics
Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Online parallel accumulation - serial fragmentation (PASEF) with a novel trapped ion mobility mass spectrometer
Meier, F., Brunner, A., Koch, S., Koch, H., Lubeck, M., Krause, M., Goedecke, N., Decker, J., Kosinski, T., Park, M. A., Bache, N., Hoerning, O., Cox, J., Räther, O. & Mann, Matthias, 2018, In: Molecular and Cellular Proteomics. 17, 12, p. 2534-2545Research output: Contribution to journal › Journal article › Research › peer-review
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Parallel accumulation - serial fragmentation combined with data-independent acquisition (diaPASEF)
Meier, F., Brunner, A., Frank, M., Ha, A., Voytik, E., Kaspar-Schoenefeld, S., Lubeck, M., Raether, O., Aebersold, R., Collins, B. C., Roest, H. L. & Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S17 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
Mehta, S., Buyanbat, A., Kai, Y., Karayel, O., Goldman, S. R., Seruggia, D., Zhang, K., Fujiwara, Y., Donovan, K. A., Zhu, Q., Yang, H., Nabet, B., Gray, N. S., Mann, Matthias, Fischer, E. S., Adelman, K. & Orkin, S. H., 18 Aug 2022, In: Cell Chemical Biology. 29, 8, p. 1273-1287.e8Research output: Contribution to journal › Journal article › Research › peer-review
Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers
Mayr, C. H., Simon, L. M., Leuschner, G., Ansari, M., Schniering, J., Geyer, P. E., Angelidis, I., Strunz, M., Singh, P., Kneidinger, N., Reichenberger, F., Silbernagel, E., Böhm, S., Adler, H., Lindner, M., Maurer, B., Hilgendorff, A., Prasse, A., Behr, J., Mann, M. & 3 others, , 2021, In: EMBO Molecular Medicine. e12871.Research output: Contribution to journal › Journal article › Research › peer-review
A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics
Marx, H., Lemeer, S., Schliep, J. E., Matheron, L., Mohammed, S., Cox, J., Mann, Matthias, Heck, A. J. R. & Kuster, B., Jun 2013, In: Nature Biotechnology. 31, 6, p. 557-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
Marinkovic, M., Fuoco, C., Sacco, F., Cerquone Perpetuini, A., Giuliani, G., Micarelli, E., Pavlidou, T., Petrilli, L. L., Reggio, A., Riccio, F., Spada, F., Vumbaca, S., Zuccotti, A., Castagnoli, L., Mann, Matthias, Gargioli, C. & Cesareni, G., Jun 2019, In: Life Science Alliance. 2, 3Research output: Contribution to journal › Journal article › Research › peer-review
Inflammatory signaling in human tuberculosis granulomas is spatially organized
Marakalala, M. J., Raju, R. M., Sharma, K., Zhang, Y. J., Eugenin, E. A., Prideaux, B., Daudelin, I. B., Chen, P., Booty, M. G., Kim, J. H., Eum, S. Y., Via, L. E., Behar, S. M., Barry, C. E., Mann, Matthias, Dartois, V. & Rubin, E. J., May 2016, In: Nature Medicine. 22, 5, p. 531-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ethical Principles, Constraints and Opportunities in Clinical Proteomics
Porsdam Mann, Sebastian, Treit, P. V., Geyer, P. E., Omenn, G. S. & Mann, Matthias, 2021, In: Molecular and Cellular Proteomics. 20, 14 p., 100046.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ever expanding scope of electrospray mass spectrometry-a 30 year journey
Mann, Matthias, 2019, In: Nature Communications. 10, 3744.Research output: Contribution to journal › Comment/debate › Research
Artificial intelligence for proteomics and biomarker discovery
Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Origins of Organellar Mapping by Protein Correlation Profiling
Mann, Matthias, 2020, In: Proteomics. 20, 23, 4 p., e1900330.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plenary Lecture Proteomics technologies for signaling, clinical applications
Mann, Matthias, 2017, p. S62. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Development, use, application of novel TIMS-Tof system
Mann, Matthias, 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S20 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Origins of mass spectrometry-based proteomics
Mann, Matthias, Nov 2016, In: Nature Reviews. Molecular Cell Biology. 17, 11, p. 678Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics for biomedicine: A half-completed journey
Mann, Matthias, 1 Feb 2012, In: EMBO Molecular Medicine. 4, 2, p. 75-77 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Coming Age of Complete, Accurate, and Ubiquitous Proteomes
Mann, Matthias, Kulak, N. A., Nagaraj, N. & Cox, J., 21 Feb 2013, In: Molecular Cell. 49, 4, p. 583-590 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Error-tolerant identification of peptides in sequence databases by peptide sequence tags
Mann, Matthias & Wilm, M., 15 Dec 1994, In: Analytical Chemistry. 66, 24, p. 4390-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphoproteins of the chicken eggshell calcified layer
Mann, K., Olsen, Jesper Velgaard, Macek, B., Gnad, F. & Mann, Matthias, 2007, In: Proteomics. 7, 1, p. 106-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
The proteome of the calcified layer organic matrix of turkey (Meleagris gallopavo) eggshell
Mann, K. & Mann, Matthias, 2013, In: Proteome Science. 11, 1, p. 40Research output: Contribution to journal › Journal article › Research › peer-review
In-depth proteomic analyses of (greenlip abalone) nacre and prismatic organic shell matrix
Mann, K., Cerveau, N., Gummich, M., Fritz, M., Mann, Matthias & Jackson, D. J., 2018, In: Proteome Science. 16, p. 11Research output: Contribution to journal › Journal article › Research › peer-review
Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis
Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
Macek, B., Gnad, F., Soufi, B., Kumar, C., Olsen, Jesper Velgaard, Mijakovic, I. & Mann, Matthias, 2007, In: Molecular and Cellular Proteomics. 7, 2, p. 299-307 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5650809
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2008
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Activation of the ATR kinase by the RPA-binding protein ETAA1
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Region and cell-type resolved quantitative proteomic map of the human heart
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Revisiting biomarker discovery by plasma proteomics
Research output: Contribution to journal › Review › Research › peer-review
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