Lars Juhl Jensen

Lars Juhl Jensen

Professor, Group Leader, Professor

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    ORCID: 0000-0001-7885-715X

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    1. Published

      ProtFus: A Comprehensive Method Characterizing Protein-Protein Interactions of Fusion Proteins

      Tagore, S., Gorohovski, A., Jensen, Lars Juhl & Frenkel-Morgenstern, M., 2019, In: PLOS Computational Biology. 15, 8, 16 p., e1007239.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Prediction of novel archaeal enzymes from sequence-derived features

      Jensen, Lars Juhl, Skovgaard, M. & Brunak, S., 2002, In: Protein Science. 11, 12, p. 2894-8 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Prediction of human protein function from post-translational modifications and localization features

      Jensen, Lars Juhl, Gupta, R., Blom, N., Devos, D., Tamames, J., Kesmir, C., Nielsen, H., Staerfeldt, H. H., Rapacki, K., Workman, C., Andersen, C. A. F., Knudsen, S., Krogh, A., Valencia, A. & Brunak, S., 2002, In: Journal of Molecular Biology. 319, 5, p. 1257-65 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Prediction of human protein function according to Gene Ontology categories

      Jensen, Lars Juhl, Gupta, R., Staerfeldt, H. & Brunak, S., 2003, In: Bioinformatics. 19, 5, p. 635-42 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Predicting biological networks from genomic data

      Harrington, E. D., Jensen, Lars Juhl & Bork, P., 2008, In: F E B S Letters. 582, 8, p. 1251-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Predicting Kinase Activity in Angiotensin Receptor Phosphoproteomes Based on Sequence-Motifs and Interactions

      Bøgebo, R., Horn, H., Olsen, Jesper Velgaard, Gammeltoft, S., Jensen, Lars Juhl, Hansen, J. L. & Christensen, G. L., 2014, In: PLOS ONE. 9, 4, p. 1-9 9 p., e94672.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Pre-Clovis mastodon hunting 13,800 years ago at the Manis site, Washington

      Waters, M. R., Stafford jr., T., McDonald, H. G., Gustafson, C., Rasmussen, M., Cappellini, Enrico, Olsen, Jesper Velgaard, Szklarczyk, D. M., Jensen, Lars Juhl, Gilbert, M Thomas P & Willerslev, Eske, 2011, In: Science. 334, 6054, p. 351-353 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

      Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer

      Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, Søren, Jensen, Lars Juhl, Cavallaro, U. & Olsen, Jesper Velgaard, 28 Mar 2017, In: Cell Reports. 18, 13, p. 3242-3256 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Phospho.ELM: a database of phosphorylation sites--update 2011

      Dinkel, H., Chica, C., Via, A., Gould, C. M., Jensen, Lars Juhl, Gibson, T. J. & Diella, F., 1 Jan 2011, In: Nucleic Acids Symposium Series. 39, Database issue, p. D261-7

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Pharos 2023: an integrated resource for the understudied human proteome

      Kelleher, K. J., Sheils, T. K., Mathias, S. L., Yang, J. J., Metzger, V. T., Siramshetty, V. B., Nguyen, D., Jensen, Lars Juhl, Vidovic, D., Schurer, S. C., Holmes, J., Sharma, K. R., Pillai, A., Bologa, C. G., Edwards, J. S., Mathe, E. A. & Oprea, T., 2023, In: Nucleic Acids Research. 51, D1, p. D1405-D1416 12 p., gkac1033.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Pharos: Collating protein information to shed light on the druggable genome

      Nguyen, D-T., Mathias, S., Bologa, C., Brunak, S., Fernandez, N., Gaulton, A., Hersey, A., Holmes, J., Jensen, L. J., Karlsson, A., Liu, G., Ma'ayan, A., Mandava, G., Mani, S., Mehta, S., Overington, J., Patel, J., Rouillard, A. D., Schürer, S., Sheils, T. & 10 others, Simeonov, A., Sklar, L. A., Southall, N., Ursu, O., Vidovic, D., Waller, A., Yang, J., Jadhav, A., Oprea, T. I. & Guha, R., Jan 2017, In: Nucleic Acids Research. 45, D1, p. D995–D1002

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Pancreatic cancer symptom trajectories from Danish registry data and free text in electronic health records

      Hjaltelin, Jessica Xin, Novitski, Sif Ingibergsdóttir, Jørgensen, Isabella Friis, Siggaard, T., Vulpius, S. A., Westergaard, David, Johansen, Julia Sidenius, Chen, I. M., Jensen, Lars Juhl & Brunak, Søren, 2023, In: eLife. 12, 15 p., e84919.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Palaeoproteomic Profiling of Conservation Layers on a 14th Century Italian Wall Painting

      Mackie, Meaghan, Rüther, P. L., Samodova-Sommer, Diana, Di Gianvincenzo, Fabiana, Granzotto, C., Lyon, D., Peggie, D. A., Howard, H., Harrison, L., Jensen, Lars Juhl, Olsen, Jesper Velgaard & Cappellini, Enrico, 2018, In: Angewandte Chemie (International ed. in English). 57, 25, p. 7369-7374 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      PREGO: A Literature and Data-Mining Resource to Associate Microorganisms, Biological Processes, and Environment Types

      Zafeiropoulos, H., Paragkamian, S., Ninidakis, S., Pavlopoulos, G. A., Jensen, Lars Juhl & Pafilis, E., 2022, In: Microorganisms. 10, 2, 22 p., 293.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Overview of the interactive task in BioCreative V

      Wang, Q., S Abdul, S., Almeida, L., Ananiadou, S., Balderas-Martínez, Y. I., Batista-Navarro, R., Campos, D., Chilton, L., Chou, H-J., Contreras, G., Cooper, L., Dai, H-J., Ferrell, B., Fluck, J., Gama-Castro, S., George, N., Gkoutos, G., Irin, A. K., Jensen, L. J., Jimenez, S. & 36 others, Jue, T. R., Keseler, I., Madan, S., Matos, S., McQuilton, P., Milacic, M., Mort, M., Natarajan, J., Pafilis, E., Pereira, E., Rao, S., Rinaldi, F., Rothfels, K., Salgado, D., Silva, R. M., Singh, O., Stefancsik, R., Su, C., Subramani, S., Tadepally, H. D., Tsaprouni, L., Vasilevsky, N., Wang, X., Chatr-Aryamontri, A., Laulederkind, S. J. F., Matis-Mitchell, S., McEntyre, J., Orchard, S., Pundir, S., Rodriguez-Esteban, R., Van Auken, K., Lu, Z., Schaeffer, M., Wu, C. H., Hirschman, L. & Arighi, C. N., 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 18 p., baw119.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Overview of the Knowledge Management Center for Illuminating the Druggable Genome

      Oprea, T. I., Bologa, C., Holmes, J., Mathias, S., Metzger, V. T., Waller, A., Yang, J. J., Leach, A. R., Jensen, Lars Juhl, Kelleher, K. J., Sheils, T. K., Mathé, E., Avram, S. & Edwards, J. S., 2024, In: Drug Discovery Today. 29, 3, 8 p., 103882.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Orphan protein function and its relation to glycosylation

      Gupta, R., Jensen, Lars Juhl & Brunak, S., 2002, In: Ernst Schering Foundation Symposium Proceedings. 38, p. 276-94 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Origin of replication in circular prokaryotic chromosomes

      Worning, P., Jensen, Lars Juhl, Hallin, P. F., Staerfeldt, H. & Ussery, D., 2006, In: Environmental Microbiology. 8, 2, p. 353-61 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Ontologies in quantitative biology: a basis for comparison, integration, and discovery

      Jensen, Lars Juhl & Bork, P., 1 May 2010, In: PLoS Biology. 8, 5, p. e1000374

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      One tagger, many uses: Illustrating the power of ontologies in dictionary-based named entity recognition

      Jensen, Lars Juhl, 2016, In: CEUR Workshop Proceedings. 1747, 2 p.

      Research output: Contribution to journal › Conference article › Research › peer-review

    22. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      OnTheFly2.0: a text-mining web application for automated biomedical entity recognition, document annotation, network and functional enrichment analysis

      Baltoumas, F. A., Zafeiropoulou, S., Karatzas, E., Paragkamian, S., Thanati, F., Iliopoulos, I., Eliopoulos, A. G., Schneider, R., Jensen, Lars Juhl, Pafilis, E. & Pavlopoulos, G. A., 2021, In: NAR Genomics and Bioinformatics. 3, 4, 10 p., lqab090.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      On the total number of genes and their length distribution in complete microbial genomes

      Skovgaard, M., Jensen, Lars Juhl, Brunak, Søren, Ussery, D. & Krogh, Anders, 2001, In: Trends in Genetics. 17, 8, p. 425-8 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. NetworKIN: a resource for exploring cellular phosphorylation networks

      Linding, R., Jensen, Lars Juhl, Pasculescu, A., Olhovsky, M., Colwill, K., Bork, P., Yaffe, M. B. & Pawson, T., 2008, In: Nucleic Acids Research. 36, Database issue, p. D695-9

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      Myeloma-induced bone pain: lessons learnt from a localized, immunocompetent mouse model

      Diaz-delCastillo, M., Nemler, T., Thygesen, D. M., Chavez-Saldana, N. A., Vazquez-Mora, J. A., Palasca, Oana, Jensen, Lars Juhl, Evans, H., Andrews, R. E., Mandal, A., Chantry, A. D., Lawson, M. A., Andersen, T., Jimenez-Andrade, J. M. & Heegaard, Anne-Marie, 2022, In: Clinical Lymphoma, Myeloma & Leukemia. 22, Suppl., p. S108-S108 P-133.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    27. Published

      Multiple independent analyses reveal only transcription factors as an enriched functional class associated with microRNAs

      Croft, L. J., Szklarczyk, D., Jensen, Lars Juhl & Gorodkin, Jan, 2012, In: B M C Systems Biology. 6, 1, p. 90

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Mining electronic health records: towards better research applications and clinical care

      Jensen, P. B., Jensen, Lars Juhl & Brunak, Søren, 2012, In: Nature Reviews. Genetics. 13, 6, p. 395-405 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Microblogging the ISMB: a new approach to conference reporting

      Saunders, N., Beltrão, P., Jurczak, D., Krause, R., Kuhn, M., Wu, S. & Jensen, Lars Juhl, 2009, In: PLoS Computational Biology. 5, 1, p. e1000263

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Metastatic Infiltration of Nervous Tissue and Periosteal Nerve Sprouting in Multiple Myeloma-Induced Bone Pain in Mice and Human

      Diaz-delCastillo, M., Palasca, O., Nemler, T. T., Thygesen, D. M., Chávez-Saldaña, N. A., Vázquez-Mora, J. A., Ponce Gomez, L. Y., Jensen, L. J., Evans, H., Andrews, R. E., Mandal, A., Neves, D., Mehlen, P., Caruso, J. P., Dougherty, P. M., Price, T. J., Chantry, A., Lawson, M. A., Andersen, T. L., Jimenez-Andrade, J. M. & 1 others, Heegaard, Anne-Marie, 2023, In: The Journal of Neuroscience. 43, 29, p. 5414-5430

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. Published

      Metaproteomics of saliva identifies human protein markers specific for individuals with periodontitis and dental caries compared to orally healthy controls

      Midjord-Belstrøm, Daniel, Jersie-Christensen, R. R., Lyon, D., Damgaard, Christian, Jensen, Lars Juhl, Holmstrup, Palle & Olsen, Jesper Velgaard, 2016, In: PeerJ. 4, 17 p., e2433.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level

      Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

      Bassani-Sternberg, M., Pletscher-Frankild, S., Jensen, Lars Juhl & Mann, Matthias, Mar 2015, In: Molecular and Cellular Proteomics. 14, 3, p. 658-73 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Martini: using literature keywords to compare gene sets

      Soldatos, T. G., O'Donoghue, S. I., Satagopam, V. P., Jensen, Lars Juhl, Brown, N. P., Barbosa-Silva, A. & Schneider, R., 2010, In: Nucleic Acids Research. 38, 1, p. 26-38 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Published

      Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae

      Hernández Guzmán, Ulises, Aksnes, H., Ree, R., Krogh, Nicolai, Jakobsson, M. E., Jensen, Lars Juhl, Arnesen, T. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 4517.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Literature mining for the biologist: from information retrieval to biological discovery

      Jensen, Lars Juhl, Saric, J. & Bork, P., 2006, In: Nature Reviews. Genetics. 7, 2, p. 119-29 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Linking glycemic dysregulation in diabetes to symptoms, comorbidities, and genetics through EHR data mining

      Kirk, I. K., Simon, C., Banasik, K., Holm, P. C., Haue, A. D., Jensen, P. B., Jensen, L. J., Rodriguez, C. L., Pedersen, M. K., Eriksson, R., Andersen, H. U., Almdal, T., Bork-Jensen, J., Grarup, N., Borch-Johnsen, K., Pedersen, O., Pociot, F., Hansen, T., Bergholdt, R., Rossing, P. & 1 others, Brunak, Søren, 2019, In: eLife. 8, 19 p., e44941.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Linear motif atlas for phosphorylation-dependent signaling

      Miller, M. L., Jensen, L. J., Diella, F., Jørgensen, C., Tinti, M., Li, L., Hsiung, M., Parker, S. A., Bordeaux, J., Sicheritz-Ponten, T., Olhovsky, M., Pasculescu, A., Alexander, J., Knapp, S., Blom, N., Bork, P., Li, S., Cesareni, G., Pawson, T., Turk, B. E. & 3 others, Yaffe, M. B., Brunak, Søren & Linding, R., 2008, In: Science Signaling. 1, 35, p. ra2

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Light-induced asymmetries in embryonic retinal gene expression are mediated by the vascular system and extracellular matrix

      Versace, E., Sgadò, P., George, J., Loveland, J. L., Ward, J., Thorpe, P., Jensen, Lars Juhl, Spencer, K. A., Paracchini, S. & Vallortigara, G., 2022, In: Scientific Reports. 12, 1, 12 p., 12086.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Large-scale prediction of drug-target relationships

      Kuhn, M., Campillos, M., González, P., Jensen, Lars Juhl & Bork, P., 2008, In: F E B S Letters. 582, 8, p. 1283-90 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    41. Large-scale extraction of gene regulation for model organisms in an ontological context

      Saric, J., Jensen, Lars Juhl & Rojas, I., 2005, In: In Silico Biology. 5, 1, p. 21-32 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      KinomeXplorer: an integrated platform for kinome biology studies

      Horn, H., Schoof, E. M., Kim, J., Robin, X., Miller, M. L., Diella, F., Palma, A., Cesareni, G., Jensen, Lars Juhl & Linding, R., 29 May 2014, In: Nature Methods. 11, 6, p. 603-4 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Inferring disease-associated long non-coding RNAs using genome - wide tissue expression profiles

      Pan, X., Jensen, Lars Juhl & Gorodkin, Jan, 2019, In: Bioinformatics. 35, 9, p. 1494-1502 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      In Vivo Phosphoproteomics Analysis Reveals the Cardiac Targets of β-Adrenergic Receptor Signaling

      Lundby, Alicia, Andersen, M. N., Steffensen, Annette Buur, Horn, H., Kelstrup, C. D., Francavilla, C., Jensen, Lars Juhl, Schmitt, Nicole, Thomsen, Morten Bækgaard & Olsen, Jesper Velgaard, 4 Jun 2013, In: Science Signaling. 6, 278, p. rs11 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Published

      Improving Peptide-Spectrum Matching by Fragmentation Prediction Using Hidden Markov Models

      Kirik, U., Refsgaard, J. C. & Jensen, Lars Juhl, 2019, In: Journal of Proteome Research. 18, 6, p. 2385-2396

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Improved metagenome binning and assembly using deep variational autoencoders

      Nissen, J. N., Johansen, Joachim, Allesoe, R. L., Sonderby, C. K., Armenteros, J. J. A., Grønbech, Christopher Heje, Jensen, Lars Juhl, Nielsen, H. B., Petersen, T. N., Winther, Ole & Rasmussen, Simon, 2021, In: Nature Biotechnology. 39, p. 555-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Impact of microRNA-130a on the neutrophil proteome

      Pedersen, C. C., Refsgaard, J. C., Østergaard, Ole, Jensen, Lars Juhl, Heegaard, N. H. H., Borregaard, N. & Cowland, J. B., 25 Nov 2015, In: B M C Immunology. 16, 10 p., 70.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. E-pub ahead of print

      Impact of acute alcohol consumption on circulating microbiome in asymptomatic alcohol-related liver disease

      Israelsen, M., Alvarez Silva, Maria Camila, Madsen, B. S., Hansen, C. D., Torp, N. C., Johansen, S., Hansen, J. K., Prier Lindvig, K., Insonere, J., Riviere, V., Juel, H. B., Brejnrod, A., Jensen, Lars Juhl, Thiele, M., Lelouvier, B., Hansen, Torben, Arumugam, Mani & Krag, A., 2023, (E-pub ahead of print) In: Gut. gutjnl-2023-330360.

      Research output: Contribution to journal › Letter › Research › peer-review

    49. Published

      Identifying the genes impacted by cell proliferation in proteomics and transcriptomics studies

      Locard-Paulet, Marie, Palasca, Oana & Jensen, Lars Juhl, 2022, In: PLOS Computational Biology. 18, 10, 20 p., e1010604.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Identification of tightly regulated groups of genes during Drosophila melanogaster embryogenesis

      Hooper, S. D., Boué, S., Krause, R., Jensen, Lars Juhl, Mason, C. E., Ghanim, M., White, K. P., Furlong, E. E. M. & Bork, P., 2007, In: Molecular Systems Biology. 3, p. 72

      Research output: Contribution to journal › Journal article › Research › peer-review

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