Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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DeSUMOylation of chromatin-bound proteins limits the rapid transcriptional reprogramming induced by daunorubicin in acute myeloid leukemias
Boulanger, M., Aqrouq, M., Tempé, D., Kifagi, C., Ristic, M., Akl, D., Hallal, R., Carusi, A., Gabellier, L., de Toledo, M., Sigurdsson, J-O., Kaoma, T., Andrieu-Soler, C., Forné, T., Soler, E., Hicheri, Y., Gueret, E., Vallar, L., Olsen, J. V., Cartron, G. & 2 others, , 2023, In: Nucleic Acids Research. 51, 16, 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the human phosphoproteome
Franciosa, Giulia, Martinez-Val, A. & Olsen, Jesper Velgaard, 2020, In: Nature Biotechnology. 38, p. 285-286 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Deep-time phylogenetic inference by paleoproteomic analysis of dental enamel
Taurozzi, Alberto John, Rüther, P. L., Patramanis, Ioannis, Koenig, Claire, Paterson, Ryan Sinclair, Madupe, Palesa Petunia, Harking, F. S., Welker, Frido, Mackie, Meaghan, Ramos Madrigal, Jazmin, Olsen, Jesper Velgaard & Cappellini, Enrico, 2024, (E-pub ahead of print) In: Nature Protocols. 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
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Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases
Fagernäs, Zandra Selina, Troché, Gaudry Bruno, Olsen, Jesper Velgaard & Welker, Frido, 2024, In: Journal of Proteomics. 298, 10 p., 105143.Research output: Contribution to journal › Journal article › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O., Swallow, D. M., Fotakis, A. K., Christensen, R. J., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Mackie, M., Canci, A., Bouwman, A., Ruhli, F. & 2 others, , 2015, In: American Journal of Physical Anthropology. 156, Suppl. 60, p. 319 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Direct evidence of milk consumption from ancient human dental calculus
Warinner, C., Hendy, J., Speller, C., Cappellini, E., Fischer, R., Trachsel, C., Arneborg, J., Lynnerup, N., Craig, O. E., Swallow, D. M., Fotakis, A. K., Jersie-Christensen, R. R., Olsen, J. V., Liebert, A., Montalva, N., Fiddyment, S., Charlton, S., Mackie, M. E., Canci, A., Bouwman, A. & 3 others, , 2014, In: Scientific Reports. 4, 6 p., 7104.Research output: Contribution to journal › Journal article › Research › peer-review
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Disulfide Linkage Characterization of Disulfide Bond-Containing Proteins and Peptides by Reducing Electrochemistry and Mass Spectrometry
Cramer, C. N., Haselmann, K. F., Olsen, Jesper Velgaard & Nielsen, P. K., 2 Feb 2016, In: Analytical Chemistry. 88, 3, p. 1585-1592 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation
Sampadi, B., Vermeulen, S., Mišovic, B., Boei, J. J., Batth, Tanveer Singh, Chang, J. G., Paulsen, M. T., Magnuson, B., Schimmel, J., Kool, H., Olie, C. S., Everts, B., Vertegaal, A. C. O., Olsen, Jesper Velgaard, Ljungman, M., Jeggo, P. A., Mullenders, L. H. F. & Vrieling, H., 2022, In: Cells. 11, 23, 25 p., 3794.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
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ETD-Based Proteomic Profiling Improves Arginine Methylation Identification and Reveals Novel PRMT5 Substrates
Lu, L., Ye, Z., Zhang, R., Olsen, Jesper Velgaard, Yuan, Y. & Mao, Y., 2024, In: Journal of Proteome Research. 23, 3, p. 1014-1027Research output: Contribution to journal › Journal article › Research › peer-review
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Early Pleistocene enamel proteome from Dmanisi resolves Stephanorhinus phylogeny
Cappellini, E., Welker, F., Pandolfi, L., Ramos-Madrigal, J., Samodova, D., Rüther, P. L., Fotakis, A. K., Lyon, D., Moreno-Mayar, J. V., Bukhsianidze, M., Rakownikow Jersie-Christensen, R., Mackie, M., Ginolhac, A., Ferring, R., Tappen, M., Palkopoulou, E., Dickinson, M. R., Stafford, T. W., Chan, Y. L., Götherström, A. & 23 others, , 2019, In: Nature. 574, 7776, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
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Effective representation and storage of mass spectrometry-based proteomic data sets for the scientific community
Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2011, In: Science Signaling. 4, 160, p. pe7Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells
Niss, K., Jakobsson, M. E., Westergaard, David, Belling, K. G., Olsen, Jesper Velgaard & Brunak, Søren, 2020, In: Molecular and Cellular Endocrinology. 517, 9 p., 110923.Research output: Contribution to journal › Journal article › Research › peer-review
Electron capture dissociation of singly and multiply phosphorylated peptides
Stensballe, A., Jensen, O. N., Olsen, Jesper Velgaard, Haselmann, K. F. & Zubarev, R. A., 2000, In: Rapid Communications in Mass Spectrometry. 14, 19, p. 1793-800 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Electronic excitation gives informative fragmentation of polypeptide cations and anions
Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In: European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enamel proteome sequences from Dmanisi (Georgia) enable molecular phylogeny beyond the limits of ancient DNA preservation
Cappellini, Enrico, Welker, Frido, Olsen, Jesper Velgaard, Lordkipanidze, D. & Willerslev, Eske, 2019, In: American Journal of Physical Anthropology. 168, suppl. 68, p. 35 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Enamel proteome shows that Gigantopithecus was an early diverging pongine
Welker, Frido, Ramos Madrigal, Jazmin, Kuhlwilm, M., Liao, W., Gutenbrunner, P., de Manuel, M., Samodova, D., Mackie, Meaghan, Allentoft, Morten Erik, Bacon, A., Collins, Matthew James, Cox, J., Lalueza-Fox, C., Olsen, Jesper Velgaard, Demeter, Fabrice, Wang, W., Marques-Bonet, T. & Cappellini, Enrico, 2019, In: Nature. 576, p. 262-265Research output: Contribution to journal › Journal article › Research › peer-review
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Expression and secretion of a lytic polysaccharide monooxygenase by a fast-growing cyanobacterium
Russo, D. A., Zedler, J. A. Z., Wittmann, D. N., Möllers, B., Singh, R. K., Batth, Tanveer Singh, van Oort, B., Olsen, Jesper Velgaard, Bjerrum, Morten Jannik & Jensen, Poul Erik, 2019, In: Biotechnology for Biofuels. 12, 1, 13 p., 74.Research output: Contribution to journal › Journal article › Research › peer-review
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Extending the Coverage of Lys-C/Trypsin-Based Bottom-up Proteomics by Cysteine S-Aminoethylation
Tomioka, R., Tomioka, A., Ogata, K., Chan, H. J., Chen, L. Y., Hernández Guzmán, Ulises, Xuan, Y., Olsen, Jesper Velgaard, Chen, Y. J. & Ishihama, Y., 2024, In: Journal of the American Society for Mass Spectrometry. 35, 2, p. 386-396 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Faecal proteomics as a novel method to study mammalian behaviour and physiology
Tsutaya, T., Mackie, Meaghan, Sawafuji, R., Miyabe-Nishiwaki, T., Olsen, Jesper Velgaard & Cappellini, Enrico, 2021, In: Molecular Ecology Resources. 21, 6, p. 1808-1819 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Feasibility of large-scale phosphoproteomics with higher energy collisional dissociation fragmentation
Nagaraj, N., D'Souza, R. C. J., Cox, J., Olsen, Jesper Velgaard & Mann, M., 3 Dec 2010, In: Journal of Proteome Research. 9, 12, p. 6786-94 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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From Phosphosites to Kinases
Munk, S., Refsgaard, J. C., Olsen, Jesper Velgaard & Jensen, Lars Juhl, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 307-21 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification
Notenboom, V., Hibbert, R. G., van Rossum-Fikkert, S. E., Olsen, Jesper Velgaard, Mann, Matthias & Sixma, T. K., 2007, In: Nucleic Acids Research. 35, 17, p. 5819-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.Research output: Contribution to journal › Journal article › Research › peer-review
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GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling
Tollenaere, M. A. X., Tiedje, C., Rasmussen, S., Nielsen, J. C., Vind, Anna Constance, Blasius, Melanie, Batth, Tanveer Singh, Mailand, Niels, Olsen, Jesper Velgaard, Gaestel, M. & Bekker-Jensen, Simon Holst, 2019, In: Cell Reports. 26, 13, p. 3511-3521.e4 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics
Wright, S. C., Motso, A., Koutsilieri, S., Beusch, C. M., Sabatier, Pierre Camille, Berghella, A., Blondel-Tepaz, É., Mangenot, K., Pittarokoilis, I., Sismanoglou, D. C., Le Gouill, C., Olsen, Jesper Velgaard, Zubarev, R. A., Lambert, N. A., Hauser, Alexander Sebastian, Bouvier, M. & Lauschke, V. M., 2023, In: Nature Communications. 14, 1, 13 p., 6243.Research output: Contribution to journal › Journal article › Research › peer-review
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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
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GeLCMS for in-depth protein characterization and advanced analysis of proteomes
Lundby, Alicia & Olsen, Jesper Velgaard, 1 Jan 2011, Gel-Free Proteomics Methods and Protocols. Vol. 753. p. 143-55 13 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Generic Workflow for Mapping of Complex Disulfide Bonds Using In-Source Reduction and Extracted Ion Chromatograms from Data-Dependent Mass Spectrometry
Cramer, C. N., Kelstrup, C., Olsen, Jesper Velgaard, Haselmann, K. F. & Nielsen, P. K., 2018, In: Analytical Chemistry. 90, 13, p. 8202-8210Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization
Arking, D. E., Pulit, S. L., Crotti, L., van der Harst, P., Munroe, P. B., Koopmann, T. T., Sotoodehnia, N., Rossin, E. J., Morley, M., Wang, X., Johnson, A. D., Lundby, A., Gudbjartsson, D. F., Noseworthy, P. A., Eijgelsheim, M., Bradford, Y., Tarasov, K. V., Dörr, M., Müller-Nurasyid, M., Lahtinen, A. M. & 31 others, , 22 Jun 2014, In: Nature Genetics. 46, 8, p. 826-838 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Scorrano, Gabriele, Nielsen, Sofie Holtsmark, Vetro, D. L., Sawafuji, R., Mackie, Meaghan, Margaryan, Ashot, Fotaki, Anna Katerina, Martínez-Labarga, C., Fabbri, P. F., Allentoft, Morten Erik, Carra, M., Martini, F., Rickards, O., Olsen, Jesper Velgaard, Pedersen, Mikkel Winther, Cappellini, Enrico & Sikora, Martin, 2022, In: Communications Biology. 5Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells
Galli, G. G., Carrara, M., Francavilla, C., Honnens de Lichtenberg, K., Olsen, Jesper Velgaard, Calogero, R. A. & Lund, Anders H., 16 Sep 2013, In: Molecular and Cellular Biology.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and proteomic evidence for Mycobacterium leprae in human medieval dental calculus from Trondheim, Norway
Vagene, A. J., Fotaki, Anna Katerina, Denham, S. D., Orbegozo, M., Mackie, Meaghan, Olsen, Jesper Velgaard, Cappellini, Enrico, Christophersen, A. & Gilbert, M Thomas P, 2020, In: American Journal of Physical Anthropology. 171, p. 291 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Global analysis of the yeast osmotic stress response by quantitative proteomics
Soufi, B., Kelstrup, C. D., Stoehr, G., Fröhlich, F., Walther, T. C. & Olsen, Jesper Velgaard, 2009, In: Molecular BioSystems. 5, 11, p. 1337-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells
Pines, A., Kelstrup, C. D., Vrouwe, M. G., Puigvert, J. C., Typas, D., Misovic, B., de Groot, A., von Stechow, L., van de Water, B., Danen, E. H. J., Vrieling, H., Mullenders, L. H. F. & Olsen, Jesper Velgaard, 2011, In: Molecular and Cellular Biology. 31, 24, p. 4964-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
High accuracy mass spectrometry in large-scale analysis of protein phosphorylation
Olsen, Jesper Velgaard & Macek, B., 2009, In: Methods in Molecular Biology. 492, p. 131-42 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast
Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Proteomics. 9, 20, p. 4642-4652 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Higher-energy C-trap dissociation for peptide modification analysis
Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Jones, M. J. K., Gelot, C., Munk, S., Koren, A., Kawasoe, Y., George, K. A., Santos, R. E., Olsen, Jesper Velgaard, McCarroll, S. A., Frattini, M. G., Takahashi, T. S. & Jallepalli, P. V., 2021, In: Molecular Cell. 81, 3, p. 426-441.e8 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Małecki, J. M., Odonohue, M., Kim, Y., Jakobsson, M. E., Gessa, L., Pinto, R., Wu, J., Davydova, E., Moen, A., Olsen, Jesper Velgaard, Thiede, B., Gleizes, P., Leidel, S. A. & Falnes, P. Ø., 2021, In: Nucleic Acids Research. 49, 6, p. 3185-3203 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hybrid-DIA: intelligent data acquisition integrates targeted and discovery proteomics to analyze phospho-signaling in single spheroids
Martinez Del Val, Ana, Fort, K., Koenig, Claire, van der Hoeven, Leander Roeland, Franciosa, Giulia, Moehring, T., Ishihama, Y., Chen, Y. J., Makarov, A., Xuan, Y. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 18 p., 3599.Research output: Contribution to journal › Journal article › Research › peer-review
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain
Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of animal species in skin clothing from museum collections
Schmidt, A. L., Gilbert, M Thomas P, Cappellini, Enrico & Olsen, Jesper Velgaard, 2011. 8 p.Research output: Contribution to conference › Paper › Research › peer-review
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Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders
den Hoed, M., Eijgelsheim, M., Esko, T., Brundel, B. J. J. M., Peal, D. S., Evans, D. M., Nolte, I. M., Segrè, A. V., Holm, H., Handsaker, R. E., Westra, H-J., Johnson, T., Isaacs, A., Yang, J., Lundby, A., Zhao, J. H., Kim, Y. J., Go, M. J., Almgren, P., Bochud, M. & 31 others, , 14 Apr 2013, In: Nature Genetics. 45, 6, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of new chicken egg proteins by mass spectrometry-based proteomic analysis
Mann, K., Olsen, Jesper Velgaard, MaĉEk, B., Gnad, F. & Mann, Matthias, Jun 2008, In: World's Poultry Science Journal. 64, 2, p. 209-218 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immature truncated O-glycophenotype of cancer directly induces oncogenic features
Radhakrishnan, P., Dabelsteen, S., Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, C., Vakhrushev, S. Y., Olsen, J. V., Hansen, L., Bennett, E. P., Woetmann, A., Yin, G., Chen, L., Song, H., Bak, M., Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, K. & 4 others, , 12 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9925376
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Molecular basis of Tousled-Like Kinase 2 activation
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52 Genetic Loci Influencing Myocardial Mass
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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