Jakob Nilsson

Jakob Nilsson

Professor

ORCID: 0000-0003-4100-1125

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  1. Published

    Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

    Vit, G., Hirth, A., Neugebauer, N., Kraft, B. N., Sigismondo, G., Cazzola, A., Tessmer, C., Duro, Joana Maria, Krijgsveld, J., Hofmann, I., Berger, M., Klüter, H., Niehrs, C., Nilsson, Jakob & Krämer, A., 2022, In: Cell Death Discovery. 8, 12 p., 484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Interphase APC/C-Cdc20 inhibition by cyclin A2-Cdk2 ensures efficient mitotic entry

    Hein, J. B. & Nilsson, Jakob, Mar 2016, In: Nature Communications. 7, 10 p., 10975.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities

    Kruse, T., Benz, C., Garvanska, D. H., Lindqvist, R., Mihalic, F., Coscia, F., Inturi, R., Sayadi, A., Simonetti, L., Nilsson, E., Ali, M., Kliche, J., Moliner Morro, A., Mund, A., Andersson, E., McInerney, G., Mann, M., Jemth, P., Davey, N. E., Överby, A. K. & 2 others, Nilsson, Jakob & Ivarsson, Y., 2021, In: Nature Communications. 12, 1, 13 p., 6761.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions

    Kliche, J., Garvanska, Dimitriya Hristoforova, Simonetti, L., Badgujar, D., Dobritzsch, D., Nilsson, Jakob, Davey, N. E. & Ivarsson, Y., 2023, In: Molecular Systems Biology. 19, 7, 21 p., e11164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Localization of PP2A-B56 to centromeres in Drosophila

    Hertz, Emil Peter Thrane & Nilsson, Jakob, 3 Aug 2017, In: Cell Cycle. 16, 15, p. 1385-1386 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  6. Published

    Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?

    Nilsson, Jakob, Dec 2012, In: BioEssays. 34, 12, p. 1070-7 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

    Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In: E M B O Journal. 32, 2, p. 303-314 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits

    Kruse, Thomas, Gnosa, S. P., Nasa, I., Garvanska, Dimitriya Hristoforova, Hein, J. B., Nguyen, H., Samsøe-Petersen, Jacob, Lopez-Mendez, B., Hertz, Emil Peter Thrane, Schwarz, J., Pena, H. S., Nikodemus, D., Kveiborg, Marie, Kettenbach, A. N. & Nilsson, Jakob, 2020, In: EMBO Journal. 39, 18 p., e103695.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Mps1-Ndc80: one interaction to rule them all

    Nilsson, Jakob, 10 Jun 2015, In: OncoTarget. 6, 19, p. 16822–16823 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  10. Published

    Multi-level Proteomics Identifies CT45 as a Chemosensitivity Mediator and Immunotherapy Target in Ovarian Cancer

    Coscia, F., Lengyel, E., Duraiswamy, J., Ashcroft, B., Bassani-Sternberg, M., Wierer, M., Johnson, A., Wroblewski, K., Montag, A., Yamada, S. D., López-Méndez, B., Nilsson, Jakob, Mund, Andreas, Mann, Matthias & Curtis, M., 2018, In: Cell. 175, 1, p. 159-170.e16

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

    Hein, J. B., Nguyen, H. T., Garvanska, Dimitriya Hristoforova, Nasa, I., Kruse, Thomas, Feng, Y., Lopez Mendez, B., Davey, N., Kettenbach, A. N., Fordyce, P. M. & Nilsson, Jakob, 2023, In: Molecular Systems Biology. 19, 17 p., e11782.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Protein phosphatases in the regulation of mitosis

    Nilsson, Jakob, 2019, In: The Journal of Cell Biology. 218, 2, 15 p., 395.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry

    Nasa, I., Cressey, L. E., Kruse, Thomas, Hertz, Emil Peter Thrane, Gui, J., Graves, L. M., Nilsson, Jakob & Kettenbach, A. N., 2020, In: Science Signaling. 13, 648, 15 p., eaba7823.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Regulation of mitotic progression by the spindle assembly checkpoint

    Lischetti, T. & Nilsson, Jakob, 2015, In: Molecular & Cellular Oncology. 2, 1, e970484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Response to Raaijmakers & Medema

    Zhang, G., Kruse, Thomas, Boldú, C. G., Garvanska, Dimitriya Hristoforova, Coscia, F., Mann, Matthias, Barisic, Marin & Nilsson, Jakob, 2019, In: The EMBO Journal. 38, 22, 5 p., e103547.

    Research output: Contribution to journal › Comment/debate › Research

  16. Published

    SAC during early cell divisions: Sacrificing fidelity over timely division, regulated differently across organisms Chromosome alignment and segregation are left unsupervised from the onset of development until checkpoint activity is acquired, varying from species to species

    Duro, Joana Maria & Nilsson, Jakob, 2021, In: BioEssays. 43, 3, 13 p., 2000174.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    SLiM-binding pockets: an attractive target for broad-spectrum antivirals

    Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

    Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Specificity determinants of phosphoprotein phosphatases controlling kinetochore functions

    Garvanska, Dimitriya Hristoforova & Nilsson, Jakob, 2020, In: Essays in Biochemistry. 64, 2, p. 325-336

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint

    Hein, J. B. & Nilsson, Jakob, 25 Jan 2014, In: E M B O Reports. 15, p. 264-272

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

    Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, Leitner, A. & Westermarck, J., 2023, In: Nature Communications. 14, 18 p., 1143.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site

    Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, Jakob & Blundell, T. L., 9 Nov 2011, In: Structure. 19, 11, p. 1691-700 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Synergistic inhibition of the APC/C by the removal of APC15 in HCT116 cells lacking UBE2C

    Garvanska, Dimitriya Hristoforova, Larsen, Marie Sofie Yoo & Nilsson, Jakob, 2 Sep 2016, In: Biology Open. 5, p. 1441-1448

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

    Nilsson, Jakob, Yekezare, M., Minshull, J. & Pines, J., 2008, In: Nature Cell Biology. 10, 12, p. 1411-20 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region

    Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In: P L o S One. 8, 4, p. e60596 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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