Jakob Nilsson

Jakob Nilsson

Professor


  1. Published

    The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing

    Lischetti, T., Zhang, G., Sedgwick, G. G., Bolanos-Garcia, V. M. & Nilsson, Jakob, Dec 2014, In: Nature Communications. 5, p. 1-12 12 p., 5563.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Regulation of mitotic progression by the spindle assembly checkpoint

    Lischetti, T. & Nilsson, Jakob, 2015, In: Molecular & Cellular Oncology. 2, 1, e970484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Quantitative kinase and phosphatase profiling reveal that CDK1 phosphorylates PP2Ac to promote mitotic entry

    Nasa, I., Cressey, L. E., Kruse, Thomas, Hertz, Emil Peter Thrane, Gui, J., Graves, L. M., Nilsson, Jakob & Kettenbach, A. N., 2020, In: Science Signaling. 13, 648, 15 p., eaba7823.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction

    Nilsson, Jakob, Yekezare, M., Minshull, J. & Pines, J., 2008, In: Nature Cell Biology. 10, 12, p. 1411-20 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mps1-Ndc80: one interaction to rule them all

    Nilsson, Jakob, 10 Jun 2015, In: OncoTarget. 6, 19, p. 16822–16823 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  6. Published

    Bub1/BubR1: swiss army knives at kinetochores

    Nilsson, Jakob, 11 Aug 2015, In: Cell Cycle. 14, 9, p. 2999-3000 2 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  7. Published

    Protein phosphatases in the regulation of mitosis

    Nilsson, Jakob, 2019, In: The Journal of Cell Biology. 218, 2, 15 p., 395.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Escape from the checkpoint: Nek2A binds a unique conformation of the APC/C-MCC complex

    Nilsson, Jakob, 2020, In: EMBO Reports. 21, 6, e50494.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?

    Nilsson, Jakob, 2011, In: BioEssays. 33, 12, p. 903-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?

    Nilsson, Jakob, Dec 2012, In: BioEssays. 34, 12, p. 1070-7 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    Can sequestering of mitotic spindle proteins cause aneuploidy? (Comment on DOI 10.1002/bies.201400175)

    Nilsson, Jakob, Mar 2015, In: BioEssays. 37, 3, p. 234 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  12. Published

    Cryo-EM structures of PP2A:B55–FAM122A and PP2A:B55–ARPP19

    Padi, S. K. R., Vos, M. R., Godek, R. J., Fuller, J. R., Kruse, Thomas, Hein, J. B., Nilsson, Jakob, Kelker, M. S., Page, R. & Peti, W., 2024, In: Nature. 625, 7993, p. 195-203 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A

    Pavic, K., Gupta, N., Omella, J. D., Derua, R., Aakula, A., Huhtaniemi, R., Määttä, J. A., Höfflin, N., Okkeri, J., Wang, Z., Kauko, O., Varjus, R., Honkanen, H., Abankwa, D., Köhn, M., Hytönen, V. P., Xu, W., Nilsson, J., Page, R., Janssens, V. & 2 others, Leitner, A. & Westermarck, J., 2023, In: Nature Communications. 14, 18 p., 1143.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development

    Pedersen, M. T., Kooistra, S. M., Radzisheuskaya, A., Laugesen, A., Johansen, Jens Vilstrup, Hayward, D. G., Nilsson, Jakob, Agger, K. & Helin, K., 15 Jul 2016, In: E M B O Journal. 35, 14, p. 1550-64 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells

    Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis

    Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex

    Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In: E M B O Journal. 32, 2, p. 303-314 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis

    Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In: Oncogene. 32, 39, p. 4622-4633 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling

    Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    SLiM-binding pockets: an attractive target for broad-spectrum antivirals

    Simonetti, L., Nilsson, Jakob, McInerney, G., Ivarsson, Y. & Davey, N. E., 2023, In: Trends in Biochemical Sciences. 48, 5, p. 420-427

    Research output: Contribution to journalReviewResearchpeer-review

  21. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A highly conserved pocket on PP2A-B56 is required for hSgo1 binding and cohesion protection during mitosis

    Ueki, Y., Hadders, M. A., Weisser, Melanie, Nasa, I., Sotelo-Parrilla, P., Cressey, L. E., Gupta, T., Hertz, Emil Peter Thrane, Kruse, Thomas, Montoya, Guillermo, Jeyaprakash, A. A., Kettenbach, A., Lens, S. M. A. & Nilsson, Jakob, 2021, In: EMBO Reports. 22, 7, 13 p., e52295.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Human SLFN5 and its Xenopus Laevis ortholog regulate entry into mitosis and oocyte meiotic resumption

    Vit, G., Hirth, A., Neugebauer, N., Kraft, B. N., Sigismondo, G., Cazzola, A., Tessmer, C., Duro, Joana Maria, Krijgsveld, J., Hofmann, I., Berger, M., Klüter, H., Niehrs, C., Nilsson, Jakob & Krämer, A., 2022, In: Cell Death Discovery. 8, 12 p., 484.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

    Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Spatial separation of phosphatase and kinase activity within the Bub complex is required for proper mitosis

    Wang, L., Kruse, Thomas, López-Méndez, B., Zhang, Y., Song, C., Zhu, L., Li, B., Fang, J., Lu, Z., Nilsson, Jakob & Zhang, G., 2023, In: Journal of Molecular Cell Biology. 14, 11, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 8799501