Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
- Published
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases
Fagernäs, Zandra Selina, Troché, Gaudry Bruno, Olsen, Jesper Velgaard & Welker, Frido, 2024, In: Journal of Proteomics. 298, 10 p., 105143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer
Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, , 2019, In: Clinical Cancer Research. 25, 2, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)
Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus
Fotaki, Anna Katerina, Denham, S. D., Mackie, Meaghan, Iraeta Orbegozo, Miren, Mylopotamitaki, Dorothea, Gopalakrishnan, Shyam, Sicheritz-Pontén, Thomas, Olsen, Jesper Velgaard, Cappellini, Enrico, KU, thw266, Christophersen, A., Gilbert, M Thomas P & Vågene, Åshild Joanne, 2020, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 375, 1812, 10 p., 20190584.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SILAC-Based Temporal Phosphoproteomics
Francavilla, C., Hekmat, O., Blagoev, B. & Olsen, Jesper Velgaard, 2014, Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): Methods and Protocols. Warscheid, B. (ed.). Vol. 1188. p. 125-48 24 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking
Francavilla, C., Papetti, M., Rigbolt, K. T. G., Pedersen, A., Sigurdsson, J. O., Cazzamali, G., Karemore, G., Blagoev, B. & Olsen, Jesper Velgaard, Jun 2016, In: Nature Structural and Molecular Biology. 23, 6, p. 608–618 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer
Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, Søren, Jensen, Lars Juhl, Cavallaro, U. & Olsen, Jesper Velgaard, 28 Mar 2017, In: Cell Reports. 18, 13, p. 3242-3256 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recent advances in kinase signaling network profiling by mass spectrometry
Franciosa, Giulia, Locard-Paulet, Marie, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2023, In: Current Opinion in Chemical Biology. 73, 11 p., 102260.Research output: Contribution to journal › Review › Research › peer-review
- Published
Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors
Franciosa, Giulia & Olsen, Jesper Velgaard, 2023, In: OncoTarget. 14, p. 281-283 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Proteomics to study cancer immunity and improve treatment
Franciosa, Giulia, Kverneland, Anders Handrup, Jensen, Agnete Witness Præst, dqp123, dqp123 & Olsen, Jesper Velgaard, 2023, In: Seminars in Immunopathology. 45, 11 p., 241–251.Research output: Contribution to journal › Review › Research › peer-review
- Published
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures
Franciosa, Giulia, Smits, J. G. A., Minuzzo, S., Martinez Del Val, Ana, Indraccolo, S. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 19 p., 2507.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deciphering the human phosphoproteome
Franciosa, Giulia, Martinez-Val, A. & Olsen, Jesper Velgaard, 2020, In: Nature Biotechnology. 38, p. 285-286 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells
Galli, G. G., Carrara, M., Francavilla, C., Honnens de Lichtenberg, K., Olsen, Jesper Velgaard, Calogero, R. A. & Lund, Anders H., 16 Sep 2013, In: Molecular and Cellular Biology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast
Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Proteomics. 9, 20, p. 4642-4652 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites
Gnad, F., Ren, S., Cox, J., Olsen, Jesper Velgaard, Macek, B., Oroshi, M. & Mann, Matthias, 2007, In: Genome Biology. 8, 11, p. R250Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway
Gruhler, A., Olsen, Jesper Velgaard, Mohammed, S., Mortensen, P., Faergeman, N. J., Mann, Matthias & Jensen, O. N., 2005, In: Molecular and Cellular Proteomics. 4, 3, p. 310-27 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae
Hernández Guzmán, Ulises, Aksnes, H., Ree, R., Krogh, Nicolai, Jakobsson, M. E., Jensen, Lars Juhl, Arnesen, T. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 4517.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C., Makarov, A. & 2 others, , 2024, (E-pub ahead of print) In: Nature Biotechnology.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FRMD6 has tumor suppressor functions in prostate cancer
Haldrup, J., Strand, S. H., Cieza-Borrella, C., Jakobsson, M. E., Riedel, M., Norgaard, M., Hedensted, S., Dagnaes-Hansen, F., Ulhoi, B. P., Eeles, R., Borre, M., Olsen, Jesper Velgaard, Thomsen, M., Kote-Jarai, Z. & Sorensen, K. D., 2021, In: Oncogene. 40, p. 763-776 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
Advantages of external accumulation for electron capture dissociation in Fourier transform mass spectrometry
Haselmann, K. F., Budnik, B. A., Olsen, Jesper Velgaard, Nielsen, Michael Lund, Reis, C. A., Clausen, H., Johnsen, A. H. & Zubarev, R. A., 2001, In: Analytical Chemistry. 73, 13, p. 2998-3005 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Electronic excitation gives informative fragmentation of polypeptide cations and anions
Haselmann, K. F., Budnik, B. A., Kjeldsen, F., Nielsen, Michael Lund, Olsen, Jesper Velgaard & Zubarev, R. A., 2002, In: European Journal of Mass Spectrometry. 8, 2, p. 117-121 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells
Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, , 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage
Hendriks, I. A., Treffers, L. W., Verlaan-de Vries, M., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 17 Mar 2015, In: Cell Reports. 10, 10, p. 1778–1791Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4)
Hendriks, I. A., Schimmel, J., Eifler, K., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 19 Jun 2015, In: The Journal of Biological Chemistry. 290, 25, p. 15526-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient proteins from ceramic vessels at Çatalhöyük West reveal the hidden cuisine of early farmers
Hendy, J., Colonese, A. C., Franz, I., Fernandes, R., Fischer, R., Orton, D., Lucquin, A., Spindler, L., Anvari, J., Stroud, E., Biehl, P. F., Speller, C., Boivin, N., Mackie, Meaghan, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Collins, Matthew James, Craig, O. E. & Rosenstock, E., 1 Dec 2018, In: Nature Communications. 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Basis of the Mechanisms Controlling MASTL
Hermida, D., Mortuza, G. B., Pedersen, A., Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry
Hinsby, A. M., Olsen, Jesper Velgaard, Bennett, K. L. & Mann, Matthias, 2003, In: Molecular and Cellular Proteomics. 2, 1, p. 29-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4
Hinsby, A. M., Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Journal of Biological Chemistry. 279, 45, p. 46438-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability (vol 46, pg 9484, 2018)
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurosson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Symposium Series. 46, 18, p. 9891-9891Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurðsson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Research. 46, 18, p. 9484-9495Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Benchmarking common quantification strategies for large-scale phosphoproteomics
Hogrebe, A., von Stechow, L., Bekker-Jensen, D. B., Weinert, B. T., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, 1, p. 1-13 1045.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphorylation of histone H3 Thr-45 is linked to apoptosis
Hurd, P. J., Bannister, A. J., Halls, K., Dawson, M. A., Vermeulen, M., Olsen, Jesper Velgaard, Ismail, H., Somers, J., Mann, M., Owen-Hughes, T., Gout, I. & Kouzarides, T., 2009, In: Journal of Biological Chemistry. 284, 24, p. 16575-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
Jakobsson, M. E., Małecki, J. M., Halabelian, L., Nilges, B. S., Pinto, R., Kudithipudi, S., Munk, S., Davydova, E., Zuhairi, F. R., Arrowsmith, C. H., Jeltsch, A., Leidel, S. A., Olsen, Jesper Velgaard & Falnes, P. Ø., 2018, In: Nature Communications. 9, 1, 3411.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative metaproteomics of medieval dental calculus reveals individual oral health status
Jersie-Christensen, R. R., Lanigan, Liam Thomas, Lyon, D., Mackie, Meaghan, Midjord-Belstrøm, Daniel, Kelstrup, C. D., Fotaki, Anna Katerina, Willerslev, Eske, Lynnerup, Niels, Jensen, Lars Juhl, Cappellini, Enrico & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, p. 1-12 4744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simple and Reproducible Sample Preparation for Single-Shot Phosphoproteomics with High Sensitivity
Jersie-Christensen, R. R., Sultan, A. & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). p. 251-60 10 p. (Methods in molecular biology (Clifton, N.J.), Vol. 1355).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
In vivo quantitative phosphoproteomic profiling identifies novel regulators of castration-resistant prostate cancer growth
Jiang, N., Hjorth-Jensen, K., Hekmat, O., Iglesias Gato, Diego, Kruse, Thomas, Wang, C., Wei, W., Ke, B., Yan, B., Niu, Y., Olsen, Jesper Velgaard & Flores Morales, A., 2015, In: Oncogene. 34, p. 2764–2776 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Jones, M. J. K., Gelot, C., Munk, S., Koren, A., Kawasoe, Y., George, K. A., Santos, R. E., Olsen, Jesper Velgaard, McCarroll, S. A., Frattini, M. G., Takahashi, T. S. & Jallepalli, P. V., 2021, In: Molecular Cell. 81, 3, p. 426-441.e8 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping cardiac remodeling in chronic kidney disease
Kaesler, N., Cheng, M., Nagai, J., O'Sullivan, J., Peisker, F., Bindels, E. M. J., Babler, A., Moellmann, J., Droste, P., Franciosa, G., Dugourd, A., Saez-Rodriguez, J., Neuss, S., Lehrke, M., Boor, P., Goettsch, C., Olsen, J. V., Speer, T., Lu, T. S., Lim, K. & 4 others, , 2023, In: Science Advances. 9, 47, 18 p., eadj4846.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1
Kamp, J. A., Lemmens, B. B. L. G., Romeijn, R. J., González-Prieto, R., Olsen, Jesper Velgaard, Vertegaal, A. C. O., van Schendel, R. & Tijsterman, M., 2022, In: Nucleic Acids Research. 50, 11, p. 6235-6250 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
Kelstrup, C. D., Jersie-Christensen, R. R., Batth, Tanveer Singh, Arrey, T. N., Kuehn, A., Kellmann, M. & Olsen, Jesper Velgaard, 28 Oct 2014, In: Journal of Proteome Research. 13, 12, p. 6187-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Performance evaluation of the Q Exactive HF-X for shotgun proteomics
Kelstrup, C. D., Bekker-Jensen, D. B., Arrey, T. N., Hogrebe, A., Harder, A. & Olsen, Jesper Velgaard, Jan 2018, In: Journal of Proteome Research. 17, 1, p. 727-738 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)
Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Limits for resolving isobaric tandem mass tag reporter ions using phase constrained spectrum deconvolution
Kelstrup, C. D., Aizikov, K., Batth, Tanveer Singh, Kreutzman, A., Grinfeld, D., Lange, O., Mourad, D., Makarov, A. A. & Olsen, Jesper Velgaard, 2 Nov 2018, In: Journal of Proteome Research. 17, 11, p. 4008-4016 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9925376
Most downloads
-
1541
downloads
Molecular basis of Tousled-Like Kinase 2 activation
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
462
downloads
52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
423
downloads
Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published