Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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α4βδ GABA receptors are high-affinity targets for γ-hydroxybutyric acid (GHB)
Absalom, N., Karim, N., Eghorn, L. F., Villumsen, I. S., Bay, T., Bräuner, Hans, Frølund, Bente, Clausen, Rasmus Prætorius, Olsen, Jesper Velgaard, Knudsen, Gitte Moos, Chebib, M. & Wellendorph, Petrine, 14 Aug 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 33, p. 13404-13409 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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qcML: an exchange format for quality control metrics from mass spectrometry experiments
Walzer, M., Pernas, L. E., Nasso, S., Bittremieux, W., Nahnsen, S., Kelchtermans, P., Pichler, P., van den Toorn, H. W. P., Staes, A., Vandenbussche, J., Mazanek, M., Taus, T., Scheltema, R. A., Kelstrup, C. D., Gatto, L., van Breukelen, B., Aiche, S., Valkenborg, D., Laukens, K., Lilley, K. S. & 9 others, , 23 Apr 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1905-1913 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle
Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, , 2022, In: E M B O Journal. 41, 17, 19 p., e111650.Research output: Contribution to journal › Journal article › Research › peer-review
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ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
Vind, Anna Constance, Snieckute, Goda, Blasius, Melanie, Tiedje, C., Krogh, Nicolai, Bekker-Jensen, D. B., Andersen, Kasper Langebjerg, Nordgaard, C., Tollenaere, M. A. X., Lund, Anders H., Olsen, Jesper Velgaard, Nielsen, Henrik & Bekker-Jensen, Simon Holst, 2020, In: Molecular Cell. 78, 4, p. 700-713.E7Research output: Contribution to journal › Journal article › Research › peer-review
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Yeast expression proteomics by high-resolution mass spectrometry
Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 1 Jan 2010, In: Methods in Enzymology. 470, p. 259-80 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein
Schimmel, J., Eifler, K., Sigurdsson, J. O., Cuijpers, S. A. G., Hendriks, I. A., Verlaan-de Vries, M., Kelstrup, C. D., Francavilla, C., Medema, R. H., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 20 Mar 2014, In: Molecular Cell. 53, 6, p. 1053-1066Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C., Makarov, A. & 2 others, , 2024, (E-pub ahead of print) In: Nature Biotechnology.Research output: Contribution to journal › Journal article › Research › peer-review
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Ubiquitin-specific Protease 11 (USP11) Deubiquitinates Hybrid Small Ubiquitin-like Modifier (SUMO)-Ubiquitin Chains to Counteract RING Finger Protein 4 (RNF4)
Hendriks, I. A., Schimmel, J., Eifler, K., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 19 Jun 2015, In: The Journal of Biological Chemistry. 290, 25, p. 15526-37 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
Akimov, V., Barrio-Hernandez, I., Hansen, S. V. F., Hallenborg, P., Pedersen, A., Bekker-Jensen, D. B., Puglia, M., Christensen, S. D. K., Vanselow, J. T., Nielsen, M. M., Kratchmarova, I., Kelstrup, C. D., Olsen, Jesper Velgaard & Blagoev, B., 2018, In: Nature Structural & Molecular Biology. 25, p. 631-640 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ubc9 sumoylation regulates SUMO target discrimination
Knipscheer, P., Flotho, A., Klug, H., Olsen, Jesper Velgaard, van Dijk, W. J., Fish, A., Johnson, E. S., Mann, M., Sixma, T. K. & Pichler, A., 2008, In: Molecular Cell. 31, 3, p. 371-82 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Tyrosine phosphoproteomics of fibroblast growth factor signaling: a role for insulin receptor substrate-4
Hinsby, A. M., Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Journal of Biological Chemistry. 279, 45, p. 46438-47 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Trypsin cleaves exclusively C-terminal to arginine and lysine residues
Olsen, Jesper Velgaard, Ong, S. & Mann, Matthias, 2004, In: Molecular and Cellular Proteomics. 3, 6, p. 608-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Truncated SALL1 Impedes Primary Cilia Function in Townes-Brocks Syndrome
Bozal-Basterra, L., Martín-Ruíz, I., Pirone, L., Liang, Y., Sigurðsson, J. O., Gonzalez-Santamarta, M., Giordano, I., Gabicagogeascoa, E., de Luca, A., Rodríguez, J. A., Wilkie, A. O. M., Kohlhase, J., Eastwood, D., Yale, C., Olsen, Jesper Velgaard, Rauchman, M., Anderson, K. V., Sutherland, J. D. & Barrio, R., 2018, In: American Journal of Human Genetics. 102, 2, p. 249-265 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Top-down protein sequencing and MS3 on a hybrid linear quadrupole ion trap-orbitrap mass spectrometer
Macek, B., Waanders, L. F., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 949-58 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation
Paul, I., Batth, Tanveer Singh, Iglesias Gato, Diego, Al-Araimi, A., Al-Haddabi, I., Alkharusi, A., Norstedt, G., Olsen, Jesper Velgaard, Zadjali, F. & Flores-Morales, A., 2017, In: Scientific Reports. 7, 14 p., 42800.Research output: Contribution to journal › Journal article › Research › peer-review
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis
Macek, B., Mijakovic, I., Olsen, Jesper Velgaard, Gnad, F., Kumar, C., Jensen, P. R. & Mann, Matthias, Feb 2008, In: Molecular and Cellular Proteomics. 6, 4, p. 697-707 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The phosphoproteome of toll-like receptor-activated macrophages
Weintz, G., Olsen, Jesper Velgaard, Frühauf, K., Niedzielska, M., Amit, I., Jantsch, J., Mages, J., Frech, C., Dölken, L., Mann, M. & Lang, R., 8 Jun 2010, In: Molecular Systems Biology. 6, p. 371Research output: Contribution to journal › Journal article › Research › peer-review
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The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Davydova, E., Shimazu, T., Schuhmacher, M. K., Jakobsson, M. E., Willemen, H. L. D. M., Liu, T., Moen, A., Ho, A. Y. Y., Małecki, J., Schroer, L., Pinto, R., Suzuki, T., Grønsberg, I. A., Sohtome, Y., Akakabe, M., Weirich, S., Kikuchi, M., Olsen, J. V., Dohmae, N., Umehara, T. & 8 others, , 2021, In: Nature Communications. 12, 14 p., 891.Research output: Contribution to journal › Journal article › Research › peer-review
The low molecular weight proteome of Halobacterium salinarum
Klein, C., Aivaliotis, M., Olsen, Jesper Velgaard, Falb, M., Besir, H., Scheffer, B., Bisle, B., Tebbe, A., Konstantinidis, K., Siedler, F., Pfeiffer, F., Mann, Matthias & Oesterhelt, D., 2007, In: Journal of Proteome Research. 6, 4, p. 1510-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins
Adachi, J., Kumar, C., Zhang, Y., Olsen, Jesper Velgaard & Mann, Matthias, 2006, In: Genome Biology. 7, 9, p. R80Research output: Contribution to journal › Journal article › Research › peer-review
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The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Pinto, R., Vågbø, C. B., Jakobsson, M. E., Kim, Y., Baltissen, M. P., O'Donohue, M., Hernández Guzmán, Ulises, Małecki, J. M., Wu, J., Kirpekar, F., Olsen, Jesper Velgaard, Gleizes, P., Vermeulen, M., Leidel, S. A., Slupphaug, G. & Falnes, P. Ø., 2020, In: Nucleic Acids Research. 48, 2, p. 830-846 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The feasibility of palaeoproteomics for studying ancient hominins from South Africa
Madupe, Palesa Petunia, Hlazo, N., Ruther, P. L., Mackie, Meaghan, Welker, Frido, Ramos Madrigal, Jazmin, Patramanis, Ioannis, Racimo, Fernando, Schroeder, L., Olsen, Jesper Velgaard, Ackermann, R. R. & Cappellini, Enrico, 2022, In: American journal of biological anthropology. 177, S73, p. 112 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The dual methyltransferase METTL13 targets N terminus and Lys55 of eEF1A and modulates codon-specific translation rates
Jakobsson, M. E., Małecki, J. M., Halabelian, L., Nilges, B. S., Pinto, R., Kudithipudi, S., Munk, S., Davydova, E., Zuhairi, F. R., Arrowsmith, C. H., Jeltsch, A., Leidel, S. A., Olsen, Jesper Velgaard & Falnes, P. Ø., 2018, In: Nature Communications. 9, 1, 3411.Research output: Contribution to journal › Journal article › Research › peer-review
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The dental proteome of Homo antecessor: {with Author Correction]
Welker, F., Ramos-Madrigal, J., Gutenbrunner, P., Mackie, M., Tiwary, S., Rakownikow Jersie-Christensen, R., Chiva, C., Dickinson, M. R., Kuhlwilm, M., de Manuel, M., Gelabert, P., Martinón-Torres, M., Margvelashvili, A., Arsuaga, J. L., Carbonell, E., Marques-Bonet, T., Penkman, K., Sabidó, E., Cox, J., Olsen, J. V. & 6 others, , Apr 2020, In: Nature. 580, 7802, p. 235-238 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The SH2 domain interaction landscape
Tinti, M., Kiemer, L., Costa, S., Miller, M. L., Sacco, F., Olsen, Jesper Velgaard, Carducci, M., Paoluzi, S., Langone, F., Workman, C., Blom, N., Machida, K., Thompson, C. M., Schutkowski, M., Brunak, Søren, Mann, Matthias, Mayer, B. J., Castagnoli, L. & Cesareni, G., 2013, In: Cell Reports. 3, 4, p. 1293-1305 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3
Ronkina, N., Shushakova, N., Tiedje, C., Yakovleva, T., Tollenaere, M. A. X., Scott, A., Batth, Tanveer Singh, Olsen, Jesper Velgaard, Helmke, A., Bekker-Jensen, Simon Holst, Clark, A. R., Kotlyarov, A. & Gaestel, M., 2019, In: Journal of immunology (Baltimore, Md. : 1950). 203, 8, p. 2291-2300 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The PI3-kinase isoform p110δ is essential for cell transformation induced by the D816V mutant of c-Kit in a lipid-kinase-independent manner
Sun, J., Mohlin, S., Lundby, Alicia, Kazi, J. U., Hellman, U., Påhlman, S., Olsen, Jesper Velgaard & Rönnstrand, L., 11 Nov 2013, In: Oncogene.Research output: Contribution to journal › Journal article › Research › peer-review
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The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores
Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In: Journal of Cell Science. p. 3243-3253 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.Research output: Contribution to journal › Journal article › Research › peer-review
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TIMP-1 increases expression and phosphorylation of proteins associated with drug resistance in breast cancer cells
Hekmat, O., Munk, S., Fogh, L., Yadav, R., Francavilla, C., Horn, H., Würtz, S. Ø., Schrohl, A-S., Damsgaard, B., Romer, M. U., Belling, K., Jensen, N. F., Gromova, I., Bekker-Jensen, D. B., Moreira, J., Jensen, L. J., Gupta, R., Lademann, U. A., Brünner, N., Olsen, J. V. & 1 others, , 5 Aug 2013, In: Journal of Proteome Research. 12, 9, p. 4136-4151 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1
Kamp, J. A., Lemmens, B. B. L. G., Romeijn, R. J., González-Prieto, R., Olsen, Jesper Velgaard, Vertegaal, A. C. O., van Schendel, R. & Tijsterman, M., 2022, In: Nucleic Acids Research. 50, 11, p. 6235-6250 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systems biology approach identifies the kinase Csnk1a1 as a regulator of the DNA damage response in embryonic stem cells
Carreras Puigvert, J., von Stechow, L., Siddappa, R., Pines, A., Bahjat, M., Haazen, L. C. J. M., Olsen, Jesper Velgaard, Vrieling, H., Meerman, J. H. N., Mullenders, L. H. F., van de Water, B. & Danen, E. H. J., 2013, In: Science Signaling. 6, 259, p. ra5 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Systems Analysis for Interpretation of Phosphoproteomics Data
Munk, S., Refsgaard, J. C. & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). Springer, Vol. 1355. p. 341-60 20 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3Research output: Contribution to journal › Journal article › Research › peer-review
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System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability
Xiao, Z., Chang, J., Hendriks, I. A., Sigurdsson, J. O., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 1 May 2015, In: Molecular and Cellular Proteomics. 14, 5, p. 1419-1434Research output: Contribution to journal › Journal article › Research › peer-review
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Structures of down syndrome kinases, DYRKs, reveal mechanisms of kinase activation and substrate recognition
Soundararajan, M., Roos, A. K., Savitsky, P., Filippakopoulos, P., Kettenbach, A. N., Olsen, Jesper Velgaard, Gerber, S., Eswaran, J., Knapp, S. & Elkins, J. M., 4 Jun 2013, In: Structure. 21, 6, p. 986-996 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Status of large-scale analysis of post-translational modifications by mass spectrometry
Olsen, Jesper Velgaard & Mann, Matthias, 1 Nov 2013, In: Molecular & Cellular Proteomics. 12, p. 3444-52Research output: Contribution to journal › Journal article › Research › peer-review
Status of complete proteome analysis by mass spectrometry: SILAC labeled yeast as a model system
de Godoy, L. M. F., Olsen, Jesper Velgaard, de Souza, G. A., Li, G., Mortensen, P. & Mann, Matthias, 2006, In: Genome Biology. 7, 6, p. R50Research output: Contribution to journal › Journal article › Research › peer-review
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Species identification of archaeological skin objects from Danish bogs: comparison between mass spectrometry-based peptide sequencing and microscopy-based methods
Brandt, Luise Ørsted, Schmidt, A. L., Mannering, U., Sarret, M., Kelstrup, C., Olsen, Jesper Velgaard & Cappellini, Enrico, 2014, In: PloS one. 9, 9, 10 p., e106875.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
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Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.Research output: Working paper › Preprint › Research
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Simple and Reproducible Sample Preparation for Single-Shot Phosphoproteomics with High Sensitivity
Jersie-Christensen, R. R., Sultan, A. & Olsen, Jesper Velgaard, 2016, Phospho-Proteomics: Methods and Protocols. Stechow, L. V. (ed.). p. 251-60 10 p. (Methods in molecular biology (Clifton, N.J.), Vol. 1355).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Signaling initiated by overexpression of the fibroblast growth factor receptor-1 investigated by mass spectrometry
Hinsby, A. M., Olsen, Jesper Velgaard, Bennett, K. L. & Mann, Matthias, 2003, In: Molecular and Cellular Proteomics. 2, 1, p. 29-36 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Separation of the gluconeogenic and mitochondrial functions of pgc-1α through s6 kinase
Lustig, Y., Ruas, J. L., Estall, J. L., Lo, J. C., Devarakonda, S., Laznik, D., Choi, J. H., Spiegelman, B. M., Ono, H. & Olsen, Jesper Velgaard, 15 Jun 2011, In: Genes & Development. 25, 12, p. 1232-1244 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SUMO-2 Orchestrates Chromatin Modifiers in Response to DNA Damage
Hendriks, I. A., Treffers, L. W., Verlaan-de Vries, M., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 17 Mar 2015, In: Cell Reports. 10, 10, p. 1778–1791Research output: Contribution to journal › Journal article › Research › peer-review
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
Pichler, A., Knipscheer, P., Oberhofer, E., van Dijk, W. J., Körner, R., Olsen, Jesper Velgaard, Jentsch, S., Melchior, F. & Sixma, T. K., 2005, In: Nature Structural and Molecular Biology. 12, 3, p. 264-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability (vol 46, pg 9484, 2018)
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurosson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Symposium Series. 46, 18, p. 9891-9891Research output: Contribution to journal › Journal article › Research › peer-review
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SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability
Hjorth-Jensen, K., Maya-Mendoza, A., Dalgaard, Nanna, Sigurðsson, J. O., Bartek, J., Iglesias Gato, Diego, Olsen, Jesper Velgaard & Flores-Morales, A., 2018, In: Nucleic Acids Research. 46, 18, p. 9484-9495Research output: Contribution to journal › Journal article › Research › peer-review
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SPIN enables high throughput species identification of archaeological bone by proteomics
Rüther, P. L., Husic, I. M., Bangsgaard, Pernille, Gregersen, K. M., Pantmann, P., Carvalho, M., Godinho, R. M., Friedl, L., Cascalheira, J., Taurozzi, Alberto John, Jørkov, M L S, Benedetti, M. M., Haws, J., Bicho, N., Welker, Frido, Cappellini, Enrico & Olsen, Jesper Velgaard, 2022, In: Nature Communications. 13, 14 p., 2458.Research output: Contribution to journal › Journal article › Research › peer-review
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SILAC-Based Temporal Phosphoproteomics
Francavilla, C., Hekmat, O., Blagoev, B. & Olsen, Jesper Velgaard, 2014, Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): Methods and Protocols. Warscheid, B. (ed.). Vol. 1188. p. 125-48 24 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Resolution of the type material of the Asian elephant, Elephas maximus Linnaeus, 1758 (Proboscidea, Elephantidae)
Cappellini, Enrico, Gentry, A., Palkopoulou, E., Ishida, Y., Cram, D., Roos, A., Watson, M., Johansson, U. S., Fernholm, B., Agnelli, P., Barbagli, F., Littlewood, D. T. J., Kelstrup, C., Olsen, Jesper Velgaard, Lister, A. M., Roca, A. L., Dalén, L. & Gilbert, M Thomas P, 2014, In: Zoological Journal of the Linnean Society. 170, 1, p. 222-232 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis
Papadopoulou, D., Roumelioti, F., Tzaferis, C., Chouvardas, P., Pedersen, A., Charalampous, F., Christodoulou-Vafeiadou, E., Ntari, L., Karagianni, N., Denis, M. C., Olsen, Jesper Velgaard, Matralis, A. N. & Kollias, G., 2023, In: JCI insight. 8, 9, 18 p., e165024.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of the golgi apparatus by p38 and JNK kinases during cellular stress responses
Nordgaard, C., Tollenaere, M. A. X., Martinez Del Val, Ana, Bekker-Jensen, D. B., Blasius, Melanie, Olsen, Jesper Velgaard & Bekker-Jensen, Simon Holst, 2021, In: International Journal of Molecular Sciences. 22, 17, 23 p., 9595.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent findings and technological advances in phosphoproteomics for cells and tissues
von Stechow, L., Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Expert Review of Proteomics. 12, 5, p. 469-87 19 p.Research output: Contribution to journal › Review › Research › peer-review
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Recent advances in kinase signaling network profiling by mass spectrometry
Franciosa, Giulia, Locard-Paulet, Marie, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2023, In: Current Opinion in Chemical Biology. 73, 11 p., 102260.Research output: Contribution to journal › Review › Research › peer-review
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Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, , 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.Research output: Contribution to journal › Letter › Research › peer-review
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Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries
Bekker-Jensen, D. B., Bernhardt, O. M., Hogrebe, A., Martinez Del Val, Ana, Verbeke, L., Gandhi, T., Kelstrup, C. D., Reiter, L. & Olsen, Jesper Velgaard, 2020, In: Nature Communications. 11, 1, 12 p., 787.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid and Deep Proteomes by Faster Sequencing on a Benchtop Quadrupole Ultra-High-Field Orbitrap Mass Spectrometer
Kelstrup, C. D., Jersie-Christensen, R. R., Batth, Tanveer Singh, Arrey, T. N., Kuehn, A., Kellmann, M. & Olsen, Jesper Velgaard, 28 Oct 2014, In: Journal of Proteome Research. 13, 12, p. 6187-95 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging
Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, , 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNF4 is required for DNA double-strand break repair in vivo
Vyas, R., Kumar, R., Clermont, F., Helfricht, A., Kalev, P., Sotiropoulou, P., Hendriks, I. A., Radaelli, E., Hochepied, T., Blanpain, C., Sablina, A., van Attikum, H., Olsen, Jesper Velgaard, Jochemsen, A. G., Vertegaal, A. C. O. & Marine, J., Mar 2013, In: Cell Death and Differentiation. 20, 3, p. 490-502 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics of human heart samples collected In vivo reveal the remodeled protein landscape of dilated left atrium without atrial fibrillation
Linscheid, N., Poulsen, P. C., Pedersen, I. D., Gregers, E., Svendsen, Jesper Hastrup, Olesen, Morten Steen Salling, Olsen, Jesper Velgaard, Delmar, M. & Lundby, Alicia, 2020, In: Molecular and Cellular Proteomics. 19, 7, p. 1132-1144Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative proteomic profiling of membrane proteins from the mouse brain cortex, hippocampus, and cerebellum using the HysTag reagent: mapping of neurotransmitter receptors and ion channels
Olsen, Jesper Velgaard, Nielsen, P. A., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2007, In: Brain Research. 1134, 1, p. 95-106 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative proteomic assessment of very early cellular signaling events
Dengjel, J., Akimov, V., Olsen, Jesper Velgaard, Bunkenborg, J., Mann, Matthias, Blagoev, B. & Andersen, J. S., 2007, In: Nature Biotechnology. 25, 5, p. 566-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action
Sampadi, B., Pines, A., Munk, S., Mišovic, B., de Groot, A. J., van de Water, B., Olsen, Jesper Velgaard, Mullenders, L. H. F. & Vrieling, H., 2020, In: Archives of Toxicology. 94, p. 1655-1671 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative phosphoproteomics dissection of 7TM receptor signaling using full and biased agonists
Christensen, G. L., Kelstrup, C., Lyngsø, C., Sarwar, U., Bøgebo, R., Sheikh, S. P., Gammeltoft, S., Olsen, Jesper Velgaard & Hansen, J. L., Jul 2010, In: Molecular and Cellular Proteomics. 9, 7, p. 1540-53 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway
Gruhler, A., Olsen, Jesper Velgaard, Mohammed, S., Mortensen, P., Faergeman, N. J., Mann, Matthias & Jensen, O. N., 2005, In: Molecular and Cellular Proteomics. 4, 3, p. 310-27 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors
Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative metaproteomics of medieval dental calculus reveals individual oral health status
Jersie-Christensen, R. R., Lanigan, Liam Thomas, Lyon, D., Mackie, Meaghan, Midjord-Belstrøm, Daniel, Kelstrup, C. D., Fotaki, Anna Katerina, Willerslev, Eske, Lynnerup, Niels, Jensen, Lars Juhl, Cappellini, Enrico & Olsen, Jesper Velgaard, 2018, In: Nature Communications. 9, p. 1-12 4744.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues
Lundby, Alicia, Secher, A., Lage, K., Nordsborg, Nikolai Baastrup, Dmytriyev, A., Lundby, C. & Olsen, Jesper Velgaard, 6 Jun 2012, In: Nature Communications. 3, p. 1-10 10 p., Article 876.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers
Vermeulen, M., Eberl, H. C., Matarese, F., Marks, H., Denissov, S., Butter, F., Lee, K. K., Olsen, Jesper Velgaard, Hyman, A. A., Stunnenberg, H. G. & Mann, M., 17 Sep 2010, In: Cell. 142, 6, p. 967-80 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protocol for high-throughput semi-automated label-free- or TMT-based phosphoproteome profiling
Koenig, Claire, Martinez Del Val, Ana, Naicker, P., Stoychev, S., Jordaan, J. & Olsen, Jesper Velgaard, 2023, In: STAR Protocols. 4, 3, 30 p., 102536.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics to study cancer immunity and improve treatment
Franciosa, Giulia, Kverneland, Anders Handrup, Jensen, Agnete Witness Præst, dqp123, dqp123 & Olsen, Jesper Velgaard, 2023, In: Seminars in Immunopathology. 45, 11 p., 241–251.Research output: Contribution to journal › Review › Research › peer-review
Proteomics strategy for quantitative protein interaction profiling in cell extracts
Sharma, K., Weber, C., Bairlein, M., Greff, Z., Kéri, G., Cox, J., Olsen, Jesper Velgaard & Daub, H., 2009, In: Nature Methods. 6, 10, p. 741-4 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures
Franciosa, Giulia, Smits, J. G. A., Minuzzo, S., Martinez Del Val, Ana, Indraccolo, S. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 19 p., 2507.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics insights into DNA damage response and translating this knowledge to clinical strategies
von Stechow, L. & Olsen, Jesper Velgaard, Feb 2017, In: Proteomics. 17, 3-4, 15 p., 1600018.Research output: Contribution to journal › Review › Research › peer-review
- Published
Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress
Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic profiling of archaeological human bone
Sawafuji, R., Cappellini, Enrico, Nagaoka, T., Fotaki, Anna Katerina, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Hirata, K. & Ueda, S., Jun 2017, In: Royal Society Open Science. 4, 6, 12 p., 161004.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomic mapping of brain plasma membrane proteins
Nielsen, P. A., Olsen, Jesper Velgaard, Podtelejnikov, A. V., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2005, In: Molecular and Cellular Proteomics. 4, 4, p. 402-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response
Beli, P., Lukashchuk, N., Wagner, S. A., Weinert, B. T., Olsen, Jesper Velgaard, Baskcomb, L., Mann, Matthias, Jackson, S. P. & Choudhary, Chunaram, 2012, In: Molecular Cell. 46, 2, p. 212-25 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
Pedersen, A., Pfeiffer, A., Karemore, G., Akimov, V., Bekker-Jensen, D. B., Blagoev, B., Francavilla, C. & Olsen, Jesper Velgaard, 2021, In: iScience. 24, 4, 34 p., 102321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic identification of beer brewing products in the ground layer of Danish Golden Age paintings
Di Gianvincenzo, Fabiana, Andersen, C. K., Filtenborg, T., Mackie, Meaghan, Ernst, M., Ramos Madrigal, Jazmin, Olsen, Jesper Velgaard, Wadum, J. & Cappellini, Enrico, 2023, In: Science Advances. 9, 21, 13 p., eade7686.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomic analysis of the acid-soluble organic matrix of the chicken calcified eggshell layer
Mann, K., Macek, B. & Olsen, Jesper Velgaard, 2006, In: Proteomics. 6, 13, p. 3801-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns
Lundby, Alicia, Hansen, K. L., Weinert, B. T., Breinholt Bekker-Jensen, D., Secher, A., Skovgaard, T., Kelstrup, C., Dmytriyev, A., Choudhary, Chunaram, Lundby, C. & Olsen, Jesper Velgaard, 30 Aug 2012, In: Cell Reports. 2, 2, p. 419-431 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of a pleistocene mammoth femur reveals more than one hundred ancient bone proteins
Cappellini, Enrico, Jensen, Lars Juhl, Szklarczyk, D. M., Ginolhac, A., Rodrigues da Fonseca, Rute Andreia, Stafford jr., T., Holen, S. R., Collins, M. J., Orlando, L. A. A., Willerslev, Eske, Gilbert, M Thomas P & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. 11, 2, p. 917-926 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues
Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation
Weinert, B. T., Wagner, S. A., Horn, H., Henriksen, P., Liu, W. R., Olsen, Jesper Velgaard, Jensen, Lars Juhl & Choudhary, Chunaram, 2011, In: Science Signaling. 4, 183, p. ra48Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome and Phosphoproteome Changes Associated with Prognosis in Acute Myeloid Leukemia
Aasebø, E., Berven, F. S., Bartaula-Brevik, S., Stokowy, T., Hovland, R., Vaudel, M., Døskeland, S. O., McCormack, E., Batth, Tanveer Singh, Olsen, Jesper Velgaard, Bruserud, Ø., Selheim, F. & Hernandez-Valladares, M., 2020, In: Cancers. 12, 3, 26 p., 709.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer
Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, , 2019, In: Clinical Cancer Research. 25, 2, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein sequences bound to mineral surfaces persist into deep time
Demarchi, B., Hall, S., Roncal-Herrero, T., Freeman, C. L., Woolley, J., Crisp, M. K., Wilson, J., Fotakis, A. K., Fischer, R., Kessler, B. M., Jersie-Christensen, R. R., Olsen, J. V., Haile, J., Thomas, J., Marean, C. W., Parkington, J., Presslee, S., Lee-Thorp, J., Ditchfield, P., Hamilton, J. F. & 16 others, , 2016, In: eLife. 5, 50 p., e17092.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein kinase A stimulates Kv7.1 surface expression by regulating Nedd4-2-dependent endocytic trafficking
Andersen, M. N., Hefting, L. L., Steffensen, Annette Buur, Schmitt, Nicole, Olesen, Søren-Peter, Olsen, Jesper Velgaard, Lundby, Alicia & Rasmussen, Hanne Borger, 15 Nov 2015, In: American Journal of Physiology: Cell Physiology. 309, 10, p. C693-C706 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein aggregation capture on microparticles enables multi-purpose proteomics sample preparation
Batth, Tanveer Singh, Tollenaere, M. A. X., Rüther, P. L., Gonzalez-Franquesa, A., Prabhakar, B. S., Bekker-Jensen, Simon Holst, Deshmukh, Atul Shahaji & Olsen, Jesper Velgaard, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1027-1035Research output: Contribution to journal › Journal article › Research › peer-review
Profiling the phospho-status of the BKCa channel alpha subunit in rat brain reveals unexpected patterns and complexity
Yan, J., Olsen, Jesper Velgaard, Park, K., Li, W., Bildl, W., Schulte, U., Aldrich, R. W., Fakler, B. & Trimmer, J. S., 2008, In: Molecular and Cellular Proteomics. 7, 11, p. 2188-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping
Samodova, D., Hosfield, C. M., Cramer, C. N., Giuli, M. V., Cappellini, Enrico, Franciosa, Giulia, Rosenblatt, M. M., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2020, In: Molecular & Cellular Proteomics. 19, 12, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting Kinase Activity in Angiotensin Receptor Phosphoproteomes Based on Sequence-Motifs and Interactions
Bøgebo, R., Horn, H., Olsen, Jesper Velgaard, Gammeltoft, S., Jensen, Lars Juhl, Hansen, J. L. & Christensen, G. L., 2014, In: PLOS ONE. 9, 4, p. 1-9 9 p., e94672.Research output: Contribution to journal › Journal article › Research › peer-review
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