Julien Duxin

Julien Duxin

Associate Professor - Promotion Programme

ORCID: 0000-0001-9389-4186

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  1. Published

    A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene

    Gao, Y., Guitton-Sert, L., Dessapt, J., Coulombe, Y., Rodrigue, A., Milano, L., Blondeau, A., Larsen, N. B., Duxin, Julien, Hussein, S., Fradet-Turcotte, A. & Masson, J. Y., 2023, In: Nature Communications. 14, 1, 20 p., 381.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination

    Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A safe fix for alcohol-derived DNA damage: [Alcohol-derived DNA damage fixed in two ways]

    Gallina, I. & Duxin, Julien, 2020, In: Nature. 579, 7800, p. 499-500 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  4. Published

    Crosstalk between repair pathways elicits Double Strand Breaks in alkylated DNA and implications for the action of temozolomide

    Fuchs, R. P., Isogawa, A., Paulo, J. A., Onizuka, K., Takahashi, T., Amunugama, R., Duxin, Julien & Fujii, S., 2021, In: eLife. 10, 21 p., e69544.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network

    Karanja, K. K., Cox, S. W., Duxin, Julien, Stewart, S. A. & Campbell, J. L., 1 Nov 2012, In: Cell Cycle. 11, 21, p. 3983-96 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model

    Kose, H. B., Larsen, N. B., Duxin, Julien & Yardimci, H., 2019, In: Cell Reports. 26, 8, p. 2113-2125.e6 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. FEN1 ensures telomere stability by facilitating replication fork re-initiation

    Saharia, A., Teasley, D. C., Duxin, Julien, Dao, B., Chiappinelli, K. B. & Stewart, S. A., 27 Aug 2010, In: The Journal of Biological Chemistry. 285, 35, p. 27057-66 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    How to fix DNA-protein crosslinks

    Kühbacher, U. & Duxin, Julien, 2020, In: DNA Repair. 94, 14 p., 102924.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Human Dna2 is a nuclear and mitochondrial DNA maintenance protein

    Duxin, Julien, Dao, B., Martinsson, P., Rajala, N., Guittat, L., Campbell, J. L., Spelbrink, J. N. & Stewart, S. A., Aug 2009, In: Molecular and Cellular Biology. 29, 15, p. 4274-82 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway

    Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome

    Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.

    Research output: Working paper › Preprint › Research

  12. Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication

    Duxin, Julien, Moore, H. R., Sidorova, J., Karanja, K. K., Honaker, Y., Dao, B., Piwnica-Worms, H., Campbell, J. L., Monnat, R. J. & Stewart, S. A., 22 Jun 2012, In: The Journal of Biological Chemistry. 287, 26, p. 21980-91 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1

    S.Colding-Christensen, Camilla, Kakulidis, Ellen Sofia, Arroyo Gomez, Javier, Hendriks, Ivo Alexander, Arkinson, C., Fábián, Z., Gambus, A., Mailand, Niels, Duxin, Julien & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 19 p., 8293.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Repair of a DNA-protein crosslink by replication-coupled proteolysis

    Duxin, Julien, Dewar, J. M., Yardimci, H. & Walter, J. C., 9 Oct 2014, In: Cell. 159, 2, p. 346-57 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts

    Larsen, N. B., Gao, A. O., Sparks, J. L., Gallina, I., Wu, R. A., Mann, Matthias, Räschle, M., Walter, J. C. & Duxin, Julien, 2019, In: Molecular Cell. 73, 3, p. 574-588.e7 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS

    Nittis, T., Guittat, L., LeDuc, R. D., Dao, B., Duxin, Julien, Rohrs, H., Townsend, R. R. & Stewart, S. A., Jun 2010, In: Molecular and Cellular Proteomics. 9, 6, p. 1144-56 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

    Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Targeting DNA-Protein Crosslinks via Post-Translational Modifications

    Leng, Xueyuan & Duxin, Julien, 2022, In: Frontiers in Molecular Biosciences. 9, 14 p., 944775.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair

    Sparks, J. L., Chistol, G., Gao, A. O., Räschle, M., Larsen, N. B., Mann, Matthias, Duxin, Julien & Walter, J. C., 2019, In: Cell. 176, 1-2, p. 167-181.e21

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The ubiquitin ligase RFWD3 is required for translesion DNA synthesis

    Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

    Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    What are the DNA lesions underlying formaldehyde toxicity?

    Benedict, Bente, Kristensen, S. M. & Duxin, Julien, 2024, In: DNA Repair. 138, 14 p., 103667.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. What is the DNA repair defect underlying Fanconi anemia?

    Duxin, Julien & Walter, J. C., Dec 2015, In: Current Opinion in Cell Biology. 37, p. 49-60 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

ID: 164085189