Julien Duxin
Associate Professor - Promotion Programme
Duxin Group
Blegdamsvej 3, 2200 København N., 06 Bygning 6, Building: 06-3-32
- 2009
Human Dna2 is a nuclear and mitochondrial DNA maintenance protein
Duxin, Julien, Dao, B., Martinsson, P., Rajala, N., Guittat, L., Campbell, J. L., Spelbrink, J. N. & Stewart, S. A., Aug 2009, In: Molecular and Cellular Biology. 29, 15, p. 4274-82 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS
Nittis, T., Guittat, L., LeDuc, R. D., Dao, B., Duxin, Julien, Rohrs, H., Townsend, R. R. & Stewart, S. A., Jun 2010, In: Molecular and Cellular Proteomics. 9, 6, p. 1144-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
FEN1 ensures telomere stability by facilitating replication fork re-initiation
Saharia, A., Teasley, D. C., Duxin, Julien, Dao, B., Chiappinelli, K. B. & Stewart, S. A., 27 Aug 2010, In: The Journal of Biological Chemistry. 285, 35, p. 27057-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Okazaki fragment processing-independent role for human Dna2 enzyme during DNA replication
Duxin, Julien, Moore, H. R., Sidorova, J., Karanja, K. K., Honaker, Y., Dao, B., Piwnica-Worms, H., Campbell, J. L., Monnat, R. J. & Stewart, S. A., 22 Jun 2012, In: The Journal of Biological Chemistry. 287, 26, p. 21980-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
DNA2 and EXO1 in replication-coupled, homology-directed repair and in the interplay between HDR and the FA/BRCA network
Karanja, K. K., Cox, S. W., Duxin, Julien, Stewart, S. A. & Campbell, J. L., 1 Nov 2012, In: Cell Cycle. 11, 21, p. 3983-96 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
Repair of a DNA-protein crosslink by replication-coupled proteolysis
Duxin, Julien, Dewar, J. M., Yardimci, H. & Walter, J. C., 9 Oct 2014, In: Cell. 159, 2, p. 346-57 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
What is the DNA repair defect underlying Fanconi anemia?
Duxin, Julien & Walter, J. C., Dec 2015, In: Current Opinion in Cell Biology. 37, p. 49-60 12 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Mechanism of replication-coupled DNA-protein crosslink proteolysis by SPRTN and the proteasome
Gao, A., Larsen, N., Sparks, J., Gallina, I., Mann, Matthias, Räschle, M., Walter, J. & Duxin, Julien, 2018, bioRxiv, 54 p.Research output: Working paper › Preprint › Research
- 2019
- Published
Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model
Kose, H. B., Larsen, N. B., Duxin, Julien & Yardimci, H., 2019, In: Cell Reports. 26, 8, p. 2113-2125.e6 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts
Larsen, N. B., Gao, A. O., Sparks, J. L., Gallina, I., Wu, R. A., Mann, Matthias, Räschle, M., Walter, J. C. & Duxin, Julien, 2019, In: Molecular Cell. 73, 3, p. 574-588.e7 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The CMG Helicase Bypasses DNA-Protein Cross-Links to Facilitate Their Repair
Sparks, J. L., Chistol, G., Gao, A. O., Räschle, M., Larsen, N. B., Mann, Matthias, Duxin, Julien & Walter, J. C., 2019, In: Cell. 176, 1-2, p. 167-181.e21Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
A safe fix for alcohol-derived DNA damage: [Alcohol-derived DNA damage fixed in two ways]
Gallina, I. & Duxin, Julien, 2020, In: Nature. 579, 7800, p. 499-500 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
How to fix DNA-protein crosslinks
Kühbacher, U. & Duxin, Julien, 2020, In: DNA Repair. 94, 14 p., 102924.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
Ambjørn, Sara Marie, Duxin, Julien, Hertz, Emil Peter Thrane, Nasa, I., Duro, Joana Maria, Kruse, Thomas, Lopez-Mendez, B., Rymarczyk, B., Cressey, L. E., van Overeem Hansen, T., Kettenbach, A. N., Østergaard, Vibe Hallundbæk, Lisby, Michael & Nilsson, Jakob, 2021, In: Nature Communications. 12, 1, 11 p., 5748.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crosstalk between repair pathways elicits Double Strand Breaks in alkylated DNA and implications for the action of temozolomide
Fuchs, R. P., Isogawa, A., Paulo, J. A., Onizuka, K., Takahashi, T., Amunugama, R., Duxin, Julien & Fujii, S., 2021, In: eLife. 10, 21 p., e69544.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Gallina, I., Hendriks, Ivo Alexander, Hoffmann, Saskia, Larsen, N. B., Johansen, Joachim, S.Colding-Christensen, Camilla, Schubert, Lisa, Sellés Baiget, Selene, Fábián, Z., Kühbacher, U., Gao, A. O., Räschle, M., Rasmussen, Simon, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2021, In: Molecular Cell. 81, 3, p. 442-458.e9 27 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway
Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting DNA-Protein Crosslinks via Post-Translational Modifications
Leng, Xueyuan & Duxin, Julien, 2022, In: Frontiers in Molecular Biosciences. 9, 14 p., 944775.Research output: Contribution to journal › Review › Research › peer-review
- 2023
- Published
A CRISPR-Cas9 screen identifies EXO1 as a formaldehyde resistance gene
Gao, Y., Guitton-Sert, L., Dessapt, J., Coulombe, Y., Rodrigue, A., Milano, L., Blondeau, A., Larsen, N. B., Duxin, Julien, Hussein, S., Fradet-Turcotte, A. & Masson, J. Y., 2023, In: Nature Communications. 14, 1, 20 p., 381.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Profiling ubiquitin signalling with UBIMAX reveals DNA damage- and SCFβ-Trcp1-dependent ubiquitylation of the actin-organizing protein Dbn1
S.Colding-Christensen, Camilla, Kakulidis, Ellen Sofia, Arroyo Gomez, Javier, Hendriks, Ivo Alexander, Arkinson, C., Fábián, Z., Gambus, A., Mailand, Niels, Duxin, Julien & Nielsen, Michael Lund, 2023, In: Nature Communications. 14, 19 p., 8293.Research output: Contribution to journal › Journal article › Research › peer-review
- 2024
- Published
VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates
Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What are the DNA lesions underlying formaldehyde toxicity?
Benedict, Bente, Kristensen, S. M. & Duxin, Julien, 2024, In: DNA Repair. 138, 14 p., 103667.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 164085189
Most downloads
-
259
downloads
Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
136
downloads
The ubiquitin ligase RFWD3 is required for translesion DNA synthesis
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
96
downloads
Dynamics of the Eukaryotic Replicative Helicase at Lagging-Strand Protein Barriers Support the Steric Exclusion Model
Research output: Contribution to journal › Journal article › Research › peer-review
Published