Niels Mailand

Niels Mailand

Professor, head of research, Professor

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    ORCID: 0000-0002-6623-709X

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    1. DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology

      Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity

      Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation

      Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Chemogenetic profiling reveals PP2A-independent cytotoxicity of proposed PP2A activators iHAP1 and DT-061

      Vit, G., Duro, Joana Maria, Rajendraprasad, G., Hertz, Emil Peter Thrane, Holland, L. K. K., Weisser, Melanie, McEwan, B. C., Lopez-Mendez, B., Sotelo-Parrilla, P., Jeyaprakash, A. A., Montoya, Guillermo, Mailand, Niels, Maeda, K., Kettenbach, A., Barisic, Marin & Nilsson, Jakob, 2022, In: EMBO Journal. 41, 14, e110611.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase

      Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Centriolar satellites: key mediators of centrosome functions

      Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

      Research output: Contribution to journal › Review › Research › peer-review

    7. CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis

      Mailand, Niels & Diffley, J. F. X., 23 Sep 2005, In: Cell. 122, 6, p. 915-26 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Assembly and function of DNA double-strand break repair foci in mammalian cells

      Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Dec 2010, In: D N A Repair. 9, 12, p. 1219-28 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      An unorthodox partnership in DNA repair pathway choice

      Typas, D. & Mailand, Niels, 2019, In: EMBO Reports. 20, 11, e49105.

      Research output: Contribution to journal › Editorial › Research › peer-review

    10. Published

      Ago2 facilitates Rad51 recruitment and DNA double-strand break repair by homologous recombination

      Gao, M., Wei, W., Li, M. H., Wu, Y., Ba, Z., Jin, K., Li, M., Liao, Y., Adhikari, S., Chong, Z., Zhang, T., Guo, C., Tang, T., Zhu, B., Xu, X., Mailand, Niels, Yang, Y., Qi, Y. & Danielsen, J. M. R., May 2014, In: Cell Research. 24, 5, p. 532-41 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Activation of the ATR kinase by the RPA-binding protein ETAA1

      Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      ATXN3 controls DNA replication and transcription by regulating chromatin structure

      Hernández-Carralero, E., Cabrera, E., Rodríguez-Torres, G., Hernández-Reyes, Y., Singh, A. N., Santa-María, C., Fernández-Justel, J. M., Janssens, R. C., Marteijn, J. A., Evert, B. O., Mailand, Niels, Gómez, M., Ramadan, K., Smits, V. A. J. & Freire, R., 2023, In: Nucleic Acids Research. 51, 11, p. 5396–5413

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress

      Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In: Genes & Development. 27, 22, p. 2459-2472 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

      Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

      Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

      Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      A DNA helicase remodeling proteins: How DNA-protein crosslink repair unfolds via FANCJ

      Mailand, Niels, 2023, In: Molecular Cell. 83, 1, p. 3-5 3 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

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