Matthias Mann
Professor, head of research, Professor
- 2022
- Published
Noninvasive proteomic biomarkers for alcohol-related liver disease
Niu, Lili, Thiele, M., Geyer, P. E., Rasmussen, D. N., Webel, Henry, Santos, A., Gupta, R., Meier, F., Strauss, Maximilian, Kjaergaard, M., Lindvig, K., Jacobsen, S., Rasmussen, Simon, Hansen, Torben, Krag, A. & Mann, Matthias, 2022, In: Nature Medicine. 28, 6, p. 1277-1287 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
OpenCell: Endogenous tagging for the cartography of human cellular organization
Cho, N. H., Cheveralls, K. C., Brunner, A. D., Kim, K., Michaelis, A. C., Raghavan, P., Kobayashi, H., Savy, L., Li, J. Y., Canaj, H., Kim, J. Y. S., Stewart, E. M., Gnann, C., McCarthy, F., Cabrera, J. P., Brunetti, R. M., Chhun, B. B., Dingle, G., Hein, M. Y., Huang, B. & 7 others, , 2022, In: Science. 375, 6585, eabi6983.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organ-specific metabolic pathways distinguish prediabetes, type 2 diabetes, and normal tissues
Diamanti, K., Cavalli, M., Pereira, M. J., Pan, G., Castillejo-López, C., Kumar, C., Mundt Madsen, Filip Oskar, Komorowski, J., Deshmukh, Atul Shahaji, Mann, Matthias, Korsgren, O., Eriksson, J. W. & Wadelius, C., 2022, In: Cell Reports Medicine. 3, 10, 21 p., 100763.Research output: Contribution to journal › Journal article › Research › peer-review
PLCG1 is required for AML1-ETO leukemia stem cell self-renewal
Schnoeder, T. M., Schwarzer, A., Jayavelu, A. K., Hsu, C-J., Kirkpatrick, J., Döhner, K., Perner, F., Eifert, T., Huber, N., Arreba-Tutusaus, P., Dolnik, A., Assi, S. A., Nafria, M., Jiang, L., Dai, Y-T., Chen, Z., Chen, S-J., Kellaway, S. G., Ptasinska, A., Ng, E. S. & 17 others, , 2022, In: Blood. 139, 7, p. 1080-1097 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation
Stafford, C. A., Gassauer, A. M., de Oliveira Mann, C. C., Tanzer, M. C., Fessler, E., Wefers, B., Nagl, D., Kuut, G., Sulek, K., Vasilopoulou, C., Schwojer, S. J., Wiest, A., Pfautsch, M. K., Wurst, W., Yabal, M., Fröhlich, T., Mann, Matthias, Gisch, N., Jae, L. T. & Hornung, V., 2022, In: Nature. 609, p. 590-596 28 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome profiling of cerebrospinal fluid reveals biomarker candidates for Parkinson's disease
Karayel, O., Virreira Winter, S., Padmanabhan, S., Kuras, Y. I., Vu, D. T., Tuncali, I., Merchant, K., Wills, A. M., Scherzer, C. R. & Mann, Matthias, 2022, In: Cell Reports Medicine. 3, 6, 20 p., 100661.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid and In-Depth Coverage of the (Phospho-)Proteome With Deep Libraries and Optimal Window Design for dia-PASEF
Skowronek, P., Thielert, Marvin Christoffer, Voytik, E., Tanzer, M. C., Hansen, F. M., Willems, S., Karayel, O., Brunner, A., Meier, F. & Mann, Matthias, 2022, In: Molecular and Cellular Proteomics. 21, 9, 15 p., 100279.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial characterization of single tumor cells by proteomics
Mund, Andreas & Mann, Matthias, 2022, In: Nature Biotechnology. 40, 8, p. 1186-1187 2 p.Research output: Contribution to journal › Comment/debate › Research
- Published
Spatial proteomics in three-dimensional intact specimens
Bhatia, H. S., Brunner, A-D., Öztürk, F., Kapoor, S., Rong, Z., Mai, H., Thielert, M., Ali, M., Al-Maskari, R., Paetzold, J. C., Kofler, F., Todorov, M. I., Molbay, M., Kolabas, Z. I., Negwer, M., Hoeher, L., Steinke, H., Dima, A., Gupta, B., Kaltenecker, D. & 11 others, , 2022, In: Cell. 185, 26, p. 5040-5058.e19Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The emerging role of mass spectrometry-based proteomics in drug discovery
Meissner, F., Geddes-McAlister, J., Mann, Matthias & Bantscheff, M., 2022, In: Nature Reviews Drug Discovery. 21, p. 637-654 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The structural context of posttranslational modifications at a proteome-wide scale
Bludau, I., Willems, S., Zeng, W. F., Strauss, Maximilian, Hansen, F. M., Tanzer, M. C., Karayel, O., Schulman, B. A. & Mann, Matthias, 2022, In: PLOS Biology. 20, 5, 23 p., e3001636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards Precision Dermatology: Emerging Role of Proteomic Analysis of the Skin
Fredman, G., Skov, Lone, Mann, Matthias & Dyring-Andersen, Beatrice, 2022, In: Dermatology. 238, p. 185–194Research output: Contribution to journal › Review › Research › peer-review
- Published
Ultra-high sensitivity mass spectrometry quantifies single-cell proteome changes upon perturbation
Brunner, A., Thielert, Marvin Christoffer, Vasilopoulou, C., Ammar, C., Coscia, F., Mund, Andreas, Hoerning, O. B., Bache, N., Apalategui, A., Lubeck, M., Richter, S., Fischer, D. S., Raether, O., Park, M. A., Meier, F., Theis, F. J. & Mann, Matthias, 2022, In: Molecular Systems Biology. 18, 3, 15 p., e10798.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unbiased spatial proteomics with single-cell resolution in tissues
Mund, Andreas, Brunner, A. & Mann, Matthias, 2022, In: Molecular Cell. 82, 12, p. 2335-2349 15 p.Research output: Contribution to journal › Review › Research › peer-review
- 2021
Proteomic Analysis Identifies NDUFS1 and ATP5O as Novel Markers for Survival Outcome in Prostate Cancer
Wiebringhaus, R., Pecoraro, M., Neubauer, H. A., Trachtová, K., Trimmel, B., Wieselberg, M., Pencik, J., Egger, G., Krall, C., Moriggl, R., Mann, Matthias, Hantusch, B. & Kenner, L., 30 Nov 2021, In: Cancers. 13, 23Research output: Contribution to journal › Journal article › Research › peer-review
Signaling defects associated with insulin resistance in nondiabetic and diabetic individuals and modification by sex
Haider, N., Lebastchi, J., Jayavelu, A. K., Batista, T. M., Pan, H., Dreyfuss, J. M., Carcamo-Orive, I., Knowles, J. W., Mann, Matthias & Kahn, C. R., 1 Nov 2021, In: The Journal of Clinical Investigation. 131, 21Research output: Contribution to journal › Journal article › Research › peer-review
Phosphoproteome profiling uncovers a key role for CDKs in TNF signaling
Tanzer, M. C., Bludau, I., Stafford, C. A., Hornung, V. & Mann, Matthias, 18 Oct 2021, In: Nature Communications. 12, 1, p. 6053Research output: Contribution to journal › Journal article › Research › peer-review
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation
Hoefig, K. P., Reim, A., Gallus, C., Wong, E. H., Behrens, G., Conrad, C., Xu, M., Kifinger, L., Ito-Kureha, T., Defourny, K. A. Y., Geerlof, A., Mautner, J., Hauck, S. M., Baumjohann, D., Feederle, R., Mann, Matthias, Wierer, M., Glasmacher, E. & Heissmeyer, V., 1 Sep 2021, In: Nature Communications. 12, 1, p. 5208Research output: Contribution to journal › Journal article › Research › peer-review
Artificial intelligence for proteomics and biomarker discovery
Mann, Matthias, Kumar, C., Zeng, W. & Strauss, M. T., 18 Aug 2021, In: Cell Systems. 12, 8, p. 759-770 12 p.Research output: Contribution to journal › Review › Research › peer-review
Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation - Serial Fragmentation (PASEF) in Proteomics
Meier, F., Park, M. A. & Mann, Matthias, 17 Aug 2021, (E-pub ahead of print) In: Molecular and Cellular Proteomics. p. 100138Research output: Contribution to journal › Journal article › Research › peer-review
Identification of the transcription factor MAZ as a regulator of erythropoiesis
Deen, D., Butter, F., Daniels, D. E., Ferrer-Vicens, I., Ferguson, D. C. J., Holland, M. L., Samara, V., Sloane-Stanley, J. A., Ayyub, H., Mann, Matthias, Frayne, J., Garrick, D. & Vernimmen, D., 10 Aug 2021, In: Blood advances. 5, 15, p. 3002-3015 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Identification of covalent modifications regulating immune signaling complex composition and phenotype
Frauenstein, A., Ebner, S., Hansen, F. M., Sinha, A., Phulphagar, K., Swatek, K., Hornburg, D., Mann, Matthias & Meissner, F., Jul 2021, In: Molecular Systems Biology. 17, 7, p. e10125Research output: Contribution to journal › Journal article › Research › peer-review
Multi-omics profiling of living human pancreatic islet donors reveals heterogeneous beta cell trajectories towards type 2 diabetes
Wigger, L., Barovic, M., Brunner, A-D., Marzetta, F., Schöniger, E., Mehl, F., Kipke, N., Friedland, D., Burdet, F., Kessler, C., Lesche, M., Thorens, B., Bonifacio, E., Legido-Quigley, C., Barbier Saint Hilaire, P., Delerive, P., Dahl, A., Klose, C., Gerl, M. J., Simons, K. & 7 others, , 28 Jun 2021, (E-pub ahead of print) In: Nature Metabolism.Research output: Contribution to journal › Journal article › Research › peer-review
GID E3 ligase supramolecular chelate assembly configures multipronged ubiquitin targeting of an oligomeric metabolic enzyme
Sherpa, D., Chrustowicz, J., Qiao, S., Langlois, C. R., Hehl, L. A., Gottemukkala, K. V., Hansen, F. M., Karayel, O., von Gronau, S., Prabu, J. R., Mann, Matthias, Alpi, A. F. & Schulman, B. A., 22 Apr 2021, (E-pub ahead of print) In: Molecular Cell.Research output: Contribution to journal › Journal article › Research › peer-review
Tissue-specific modulation of gene expression in response to lowered insulin signalling in Drosophila
Tain, L. S., Sehlke, R., Meilenbrock, R. L., Leech, T., Paulitz, J., Chokkalingam, M., Nagaraj, N., Grönke, S., Fröhlich, J., Atanassov, I., Mann, Matthias, Beyer, A. & Partridge, L., 21 Apr 2021, In: eLife. 10Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5650809
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Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
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515
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Region and cell-type resolved quantitative proteomic map of the human heart
Research output: Contribution to journal › Journal article › Research › peer-review
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498
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Revisiting biomarker discovery by plasma proteomics
Research output: Contribution to journal › Review › Research › peer-review
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