Matthias Mann
Professor, head of research, Professor
Overexpression of Q-rich prion-like proteins suppresses polyQ cytotoxicity and alters the polyQ interactome
Ripaud, L., Chumakova, V., Antonin, M., Hastie, A. R., Pinkert, S., Körner, R., Ruff, K. M., Pappu, R. V., Hornburg, D., Mann, Matthias, Hartl, F. U. & Hipp, M. S., 23 Dec 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 51, p. 18219-24 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3Research output: Contribution to journal › Journal article › Research › peer-review
Amyloid-like aggregating proteins cause lysosomal defects in neurons via gain-of-function toxicity
Riera-Tur, I., Schäfer, T., Hornburg, D., Mishra, A., da Silva Padilha, M., Fernández-Mosquera, L., Feigenbutz, D., Auer, P., Mann, Matthias, Baumeister, W., Klein, R., Meissner, F., Raimundo, N., Fernández-Busnadiego, R. & Dudanova, I., Mar 2022, In: Life Science Alliance. 5, 3Research output: Contribution to journal › Journal article › Research › peer-review
Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons
Riemenschneider, H., Guo, Q., Bader, J., Frottin, F., Farny, D., Kleinberger, G., Haass, C., Mann, Matthias, Hartl, F. U., Baumeister, W., Hipp, M. S., Meissner, F., Fernández-Busnadiego, R. & Edbauer, D., 2022, In: EMBO Reports. 23, 6, e53890.Research output: Contribution to journal › Journal article › Research › peer-review
Social network architecture of human immune cells unveiled by quantitative proteomics
Rieckmann, J. C., Geiger, R., Hornburg, D., Wolf, T., Kveler, K., Jarrossay, D., Sallusto, F., Shen-Orr, S. S., Lanzavecchia, A., Mann, Matthias & Meissner, F., May 2017, In: Nature Immunology. 18, 5, p. 583-593 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Atomic-resolution mapping of transcription factor-DNA interactions by femtosecond laser crosslinking and mass spectrometry
Reim, A., Ackermann, R., Font-Mateu, J., Kammel, R., Beato, M., Nolte, S., Mann, Matthias, Russmann, C. & Wierer, M., 15 Jun 2020, In: Nature Communications. 11, 1, p. 3019Research output: Contribution to journal › Journal article › Research › peer-review
SHP1 regulates a STAT6-ITGB3 axis in FLT3ITD-positive AML cells
Reich, D., Kresinsky, A., Müller, J. P., Bauer, R., Kallenbach, J., Schnoeder, T. M., Heidel, F. H., Fässler, R., Mann, Matthias, Böhmer, F. & Jayavelu, A. K., 2020, In: Leukemia. 34, p. 1444-1449Research output: Contribution to journal › Letter › Research › peer-review
Defective glycosylation and multisystem abnormalities characterize the primary immunodeficiency XMEN disease
Ravell, J. C., Matsuda-Lennikov, M., Chauvin, S. D., Zou, J., Biancalana, M., Deeb, S. J., Price, S., Su, H. C., Notarangelo, G., Jiang, P., Morawski, A., Kanellopoulou, C., Binder, K. W., Mukherjee, R., Anibal, J. T., Sellers, B., Zheng, L., He, T., George, A. B., Pittaluga, S. & 34 others, , 5 Nov 2019, (E-pub ahead of print) In: The Journal of Clinical Investigation.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LifeTime and improving European healthcare through cell-based interceptive medicine
Rajewsky, N., Almouzni, G., Gorski, S. A., Aerts, S., Amit, I., Bertero, M. G., Bock, C., Bredenoord, A. L., Cavalli, G., Chiocca, S., Clevers, H., De Strooper, B., Eggert, A., Ellenberg, J., Fernández, X. M., Figlerowicz, M., Gasser, S. M., Hubner, N., Kjems, J., Knoblich, J. A. & 31 others, , 2020, In: Nature. 587, 7834, p. 377-386 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response
Radovanac, K., Morgner, J., Schulz, J., Blumbach, K., Patterson, C., Geiger, T., Mann, Matthias, Krieg, T., Eckes, B., Fässler, R. & Wickström, S. A., 15 May 2013, In: E M B O Journal. 32, 10, p. 1409-24 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
D13 Saliva biomarker discovery in Huntington’s disease
Qvist, Filippa Liliendahl, Hellem, M. N., Nielsen, Jørgen Erik, Mann, Matthias & Skotte, Niels Henning, 2022, In: Journal of Neurology, Neurosurgery and Psychiatry. 93, Suppl. 1, p. A24-A25Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
Cryo-EM structures of Gid12-bound GID E3 reveal steric blockade as a mechanism inhibiting substrate ubiquitylation
Qiao, S., Lee, C., Sherpa, D., Chrustowicz, J., Cheng, J., Duennebacke, M., Steigenberger, B., Karayel, O., Vu, D. T., von Gronau, S., Mann, Matthias, Wilfling, F. & Schulman, B. A., 2022, In: Nature Communications. 13, 3041.Research output: Contribution to journal › Journal article › Research › peer-review
Interconversion between Anticipatory and Active GID E3 Ubiquitin Ligase Conformations via Metabolically Driven Substrate Receptor Assembly
Qiao, S., Langlois, C. R., Chrustowicz, J., Sherpa, D., Karayel, O., Hansen, F. M., Beier, V., von Gronau, S., Bollschweiler, D., Schäfer, T., Alpi, A. F., Mann, Matthias, Prabu, J. R. & Schulman, B. A., 1 Nov 2019, (E-pub ahead of print) In: Molecular Cell.Research output: Contribution to journal › Journal article › Research › peer-review
Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation
Pünzeler, S., Link, S., Wagner, G., Keilhauer, E. C., Kronbeck, N., Spitzer, R. M., Leidescher, S., Markaki, Y., Mentele, E., Regnard, C., Schneider, K., Takahashi, D., Kusakabe, M., Vardabasso, C., Zink, L. M., Straub, T., Bernstein, E., Harata, M., Leonhardt, H., Mann, M. & 2 others, , 1 Aug 2017, In: E M B O Journal. 36, 15, p. 2263-2279 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
JAZF1, A Novel p400/TIP60/NuA4 Complex Member, Regulates H2A.Z Acetylation at Regulatory Regions
Procida, T., Friedrich, T., Jack, A. P. M., Peritore, M., Bönisch, C., Eberl, H. C., Daus, N., Kletenkov, K., Nist, A., Stiewe, T., Borggrefe, T., Mann, Matthias, Bartkuhn, M. & Hake, S. B., 12 Jan 2021, In: International Journal of Molecular Sciences. 22, 2Research output: Contribution to journal › Journal article › Research › peer-review
The Atherosclerosis Risk Variant rs2107595 Mediates Allele-Specific Transcriptional Regulation of HDAC9 via E2F3 and Rb1
Prestel, M., Prell-Schicker, C., Webb, T., Malik, R., Lindner, B., Ziesch, N., Rex-Haffner, M., Röh, S., Viturawong, T., Lehm, M., Mokry, M., den Ruijter, H., Haitjema, S., Asare, Y., Söllner, F., Najafabadi, M. G., Aherrahrou, R., Civelek, M., Samani, N. J., Mann, M. & 2 others, , Oct 2019, In: Stroke. 50, 10, p. 2651-2660 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment
Powers, N. R., Eicher, J. D., Butter, F., Kong, Y., Miller, L. L., Ring, S. M., Mann, Matthias & Gruen, J. R., 11 Jul 2013, In: American Journal of Human Genetics. 93, 1, p. 19-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Opinion: Advocating for science progress as a human right
Porsdam Mann, Sebastian, Donders, Y., Mitchell, C., Bradley, V. J., Chou, M. F., Mann, Matthias, Church, G. & Porsdam, Helle, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 43, p. 10820-10823 4 p.Research output: Contribution to journal › Comment/debate › Communication
YBX1 mediates translation of oncogenic transcripts to control cell competition in AML
Perner, F., Schnoeder, T. M., Xiong, Y., Jayavelu, A. K., Mashamba, N., Santamaria, N. T., Huber, N., Todorova, K., Hatton, C., Perner, B., Eifert, T., Murphy, C., Hartmann, M., Hoell, J. I., Schröder, N., Brandt, S., Hochhaus, A., Mertens, P. R., Mann, M., Armstrong, S. A. & 2 others, , Feb 2022, In: Leukemia. 36, 2, p. 426-437 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Proteomic and genetic analyses demonstrate that Plasmodium berghei blood stages export a large and diverse repertoire of proteins
Pasini, E. M., Braks, J. A., Fonager, J., Klop, O., Aime, E., Spaccapelo, R., Otto, T. D., Berriman, M., Hiss, J. A., Thomas, A. W., Mann, Matthias, Janse, C. J., Kocken, C. H. M. & Franke-Fayard, B., Feb 2013, In: Molecular & Cellular Proteomics. 12, 2, p. 426-48 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cohort profile: the MUNICH Preterm and Term Clinical study (MUNICH-PreTCl), a neonatal birth cohort with focus on prenatal and postnatal determinants of infant and childhood morbidity
Pangratz-Fuehrer, S., Genzel-Boroviczény, O., Bodensohn, W. E., Eisenburger, R., Scharpenack, J., Geyer, P. E., Müller-Reif, J. B., van Hagen, N., Müller, A. M., Jensen, Majken Karoline, Klein, C., Mann, Matthias & Nussbaum, C., 2021, In: BMJ Open. 11, 6, 13 p., e050652.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors
Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation
Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap
Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 5650809
Most downloads
-
2009
downloads
Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
515
downloads
Region and cell-type resolved quantitative proteomic map of the human heart
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
498
downloads
Revisiting biomarker discovery by plasma proteomics
Research output: Contribution to journal › Review › Research › peer-review
Published