Matthias Mann

Matthias Mann

Professor, head of research, Professor

Member of:

    ORCID: 0000-0003-1292-4799

    Publication year:
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    101 - 150 out of 359Page size: 50
    1. 2016

    2. Molecular basis of PRC1 targeting to Polycomb response elements by PhoRC

      Frey, F., Sheahan, T., Finkl, K., Stoehr, G., Mann, Matthias, Benda, C. & Müller, J., 1 May 2016, In: Genes & Development. 30, 9, p. 1116-27 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

      Geiger, R., Rieckmann, J. C., Wolf, T., Basso, C., Feng, Y., Fuhrer, T., Kogadeeva, M., Picotti, P., Meissner, F., Mann, Matthias, Zamboni, N., Sallusto, F. & Lanzavecchia, A., 20 Oct 2016, In: Cell. 167, 3, p. 829-842.e13

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Plasma Proteome Profiling to Assess Human Health and Disease

      Geyer, P. E., Kulak, N. A., Pichler, G., Holdt, L. M., Teupser, D. & Mann, Matthias, 23 Mar 2016, In: Cell Systems. 2, 3, p. 185-95 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Proteomics reveals the effects of sustained weight loss on the human plasma proteome

      Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. MicroRNAs of the miR-290-295 Family Maintain Bivalency in Mouse Embryonic Stem Cells

      Graham, B., Marcais, A., Dharmalingam, G., Carroll, T., Kanellopoulou, C., Graumann, J., Nesterova, T. B., Bermange, A., Brazauskas, P., Xella, B., Kriaucionis, S., Higgs, D. R., Brockdorff, N., Mann, Matthias, Fisher, A. G. & Merkenschlager, M., 10 May 2016, In: Stem Cell Reports. 6, 5, p. 635-642 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Ultra-deep and quantitative saliva proteome reveals dynamics of the oral microbiome

      Grassl, N., Kulak, N. A., Pichler, G., Geyer, P. E., Jung, J., Schubert, S., Sinitcyn, P., Cox, J. & Mann, Matthias, 21 Apr 2016, In: Genome Medicine. 8, 13 p., 44.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. PLEKHA7 Recruits PDZD11 to Adherens Junctions to Stabilize Nectins

      Guerrera, D., Shah, J., Vasileva, E., Sluysmans, S., Méan, I., Jond, L., Poser, I., Mann, Matthias, Hyman, A. A. & Citi, S., 20 May 2016, In: The Journal of Biological Chemistry. 291, 21, p. 11016-29 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Activation of the ATR kinase by the RPA-binding protein ETAA1

      Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

      Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

      Research output: Contribution to journal › Letter › Research › peer-review

    11. Published

      TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

      Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Circular non-coding RNA ANRIL modulates ribosomal RNA maturation and atherosclerosis in humans

      Holdt, L. M., Stahringer, A., Sass, K., Pichler, G., Kulak, N. A., Wilfert, W., Kohlmaier, A., Herbst, A., Northoff, B. H., Nicolaou, A., Gäbel, G., Beutner, F., Scholz, M., Thiery, J., Musunuru, K., Krohn, K., Mann, Matthias & Teupser, D., 19 Aug 2016, In: Nature Communications. 7, p. 12429

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The Proteome of Primary Prostate Cancer

      Iglesias Gato, Diego, Wikström, P., Tyanova, S., Lavallee, C., Thysell, E., Carlsson, J., Hägglöf, C., Cox, J., Andrén, O., Stattin, P., Egevad, L., Widmark, A., Bjartell, A., Collins, C. C., Bergh, A., Geiger, T., Mann, Matthias & Flores-Morales, A., May 2016, In: European Urology. 69, 5, p. 942-952 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. HCD Fragmentation of Glycated Peptides

      Keilhauer, E. C., Geyer, P. E. & Mann, Matthias, 5 Aug 2016, In: Journal of Proteome Research. 15, 8, p. 2881-90 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors

      Kim, Y. E., Hosp, F., Frottin, F., Ge, H., Mann, Matthias, Hayer-Hartl, M. & Hartl, F. U., 15 Sep 2016, In: Molecular Cell. 63, 6, p. 951-64 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Erratum: Evidence of extrapancreatic glucagon secretion in man. Diabetes 2016;65:585-597

      Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 1 Jun 2016, In: Diabetes. 65, 6, p. 1752 1 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    17. Published

      Evidence of Extrapancreatic Glucagon Secretion in Man

      Lund, Asger Bach, Bagger, J. I., Albrechtsen, Nicolai Jacob Wewer, Christensen, M., Grøndahl, M., Hartmann, Bolette, Mathiesen, Elisabeth, Hansen, C. P., Storkholm, J. H., van Hall, Gerrit, Rehfeld, Jens Frederik, Hornburg, D., Meissner, F., Mann, Matthias, Larsen, S., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Mar 2016, In: Diabetes. 65, 3, p. 585-597 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. p53 down-regulates SARS coronavirus replication and is targeted by the SARS-unique domain and PLpro via E3 ubiquitin ligase RCHY1

      Ma-Lauer, Y., Carbajo-Lozoya, J., Hein, M. Y., Müller, M. A., Deng, W., Lei, J., Meyer, B., Kusov, Y., von Brunn, B., Bairad, D. R., Hünten, S., Drosten, C., Hermeking, H., Leonhardt, H., Mann, Matthias, Hilgenfeld, R. & von Brunn, A., 30 Aug 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 35, p. E5192-201

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Origins of mass spectrometry-based proteomics

      Mann, Matthias, Nov 2016, In: Nature Reviews. Molecular Cell Biology. 17, 11, p. 678

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Inflammatory signaling in human tuberculosis granulomas is spatially organized

      Marakalala, M. J., Raju, R. M., Sharma, K., Zhang, Y. J., Eugenin, E. A., Prideaux, B., Daudelin, I. B., Chen, P., Booty, M. G., Kim, J. H., Eum, S. Y., Via, L. E., Behar, S. M., Barry, C. E., Mann, Matthias, Dartois, V. & Rubin, E. J., May 2016, In: Nature Medicine. 22, 5, p. 531-8 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. IKAP: A heuristic framework for inference of kinase activities from Phosphoproteomics data

      Mischnik, M., Sacco, F., Cox, J., Schneider, H., Schäfer, M., Hendlich, M., Crowther, D., Mann, Matthias & Klabunde, T., 1 Feb 2016, In: Bioinformatics (Online). 32, 3, p. 424-31 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Circadian control of oscillations in mitochondrial rate-limiting enzymes and nutrient utilization by PERIOD proteins

      Neufeld-Cohen, A., Robles, M. S., Aviram, R., Manella, G., Adamovich, Y., Ladeuix, B., Nir, D., Rousso-Noori, L., Kuperman, Y., Golik, M., Mann, Matthias & Asher, G., 22 Mar 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 12, p. E1673-82

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State

      Sacco, F., Silvestri, A., Posca, D., Pirrò, S., Gherardini, P. F., Castagnoli, L., Mann, Matthias & Cesareni, G., 23 Mar 2016, In: Cell Systems. 2, 3, p. 159-71 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Glucose-regulated and drug-perturbed phosphoproteome reveals molecular mechanisms controlling insulin secretion

      Sacco, F., Humphrey, S. J., Cox, J., Mischnik, M., Schulte, A., Klabunde, T., Schäfer, M. & Mann, Matthias, 14 Nov 2016, In: Nature Communications. 7, p. 13250

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. A genome-wide resource for the analysis of protein localisation in Drosophila

      Sarov, M., Barz, C., Jambor, H., Hein, M. Y., Schmied, C., Suchold, D., Stender, B., Janosch, S., K J, V. V., Krishnan, R. T., Krishnamoorthy, A., Ferreira, I. R. S., Ejsmont, R. K., Finkl, K., Hasse, S., Kämpfer, P., Plewka, N., Vinis, E., Schloissnig, S., Knust, E. & 6 others, Hartenstein, V., Mann, Matthias, Ramaswami, M., VijayRaghavan, K., Tomancak, P. & Schnorrer, F., 20 Feb 2016, In: eLife. 5, p. e12068

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Glutathione peroxidase 3 localizes to the epithelial lining fluid and the extracellular matrix in interstitial lung disease

      Schamberger, A. C., Schiller, H. B., Fernandez, I. E., Sterclova, M., Heinzelmann, K., Hennen, E., Hatz, R., Behr, J., Vašáková, M., Mann, Matthias, Eickelberg, O. & Staab-Weijnitz, C. A., 20 Jul 2016, In: Scientific Reports. 6, p. 29952

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. C9ORF72 interaction with cofilin modulates actin dynamics in motor neurons

      Sivadasan, R., Hornburg, D., Drepper, C., Frank, N., Jablonka, S., Hansel, A., Lojewski, X., Sterneckert, J., Hermann, A., Shaw, P. J., Ince, P. G., Mann, Matthias, Meissner, F. & Sendtner, M., Dec 2016, In: Nature Neuroscience. 19, 12, p. 1610-1618 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

      Steger, M., Tonelli, F., Ito, G., Davies, P., Trost, M., Vetter, M., Wachter, S., Lorentzen, E., Duddy, G., Wilson, S., Baptista, M. A., Fiske, B. K., Fell, M. J., Morrow, J. A., Reith, A. D., Alessi, D. R. & Mann, Matthias, 29 Jan 2016, In: eLife. 5

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Homology-driven assembly of NOn-redundant protEin sequence sets (NOmESS) for mass spectrometry

      Temu, T., Mann, Matthias, Räschle, M. & Cox, J., 1 May 2016, In: Bioinformatics (Online). 32, 9, p. 1417-9 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      Proteomic maps of breast cancer subtypes

      Tyanova, S., Albrechtsen, Reidar, Kronqvist, P., Cox, J., Mann, Matthias & Geiger, T., 4 Jan 2016, In: Nature Communications. 7, 11 p., 10259.

      Research output: Contribution to journal › Journal article › Research › peer-review

    31. The Perseus computational platform for comprehensive analysis of (prote)omics data

      Tyanova, S., Temu, T., Sinitcyn, P., Carlson, A., Hein, M. Y., Geiger, T., Mann, Matthias & Cox, J., Sep 2016, In: Nature Methods. 13, 9, p. 731-40 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

      Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Proteomics to study DNA-bound and chromatin-associated gene regulatory complexes

      Wierer, M. & Mann, Matthias, 1 Oct 2016, In: Human Molecular Genetics. 25, R2, p. R106-R114

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. A Proteomics Approach to the Protein Normalization Problem: Selection of Unvarying Proteins for MS-Based Proteomics and Western Blotting

      Wiśniewski, J. R. & Mann, Matthias, 1 Jul 2016, In: Journal of Proteome Research. 15, 7, p. 2321-6 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    35. Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA

      Woerner, A. C., Frottin, F., Hornburg, D., Feng, L. R., Meissner, F., Patra, M., Tatzelt, J., Mann, Matthias, Winklhofer, K. F., Hartl, F. U. & Hipp, M. S., 8 Jan 2016, In: Science (New York, N.Y.). 351, 6269, p. 173-6 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. 2017
    37. Published

      Circulating Glucagon 1-61 Regulates Blood Glucose by Increasing Insulin Secretion and Hepatic Glucose Production

      Albrechtsen, N. J. W., Kuhre, R. E., Hornburg, D., Jensen, C. Z., Hornum, M., Dirksen, C., Svane, M., Gasbjerg, L. S., Jorgensen, N. B., Gabe, M. N., Balk-Moller, E., Albrechtsen, R., Winther-Sorensen, M., Galsgaard, K. D., Meissner, F., Jorsal, T., Lund, A., Vilsboll, T., Eliasen, R., Bojsen-Moller, K. N. & 9 others, Idorn, T., Deacon, Carolyn F., Knop, Filip Krag, Rosenkilde, Mette, Hartmann, Bolette, Feldt-Rasmussen, Bo, Mann, Matthias, Madsbad, Sten & Holst, Jens Juul, Nov 2017, In: Cell Reports. 21, 6, p. 1452-1460

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. CRL2(Lrr1) promotes unloading of the vertebrate replisome from chromatin during replication termination

      Dewar, J. M., Low, E., Mann, Matthias, Räschle, M. & Walter, J. C., 1 Feb 2017, In: Genes & Development. 31, 3, p. 275-290 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Region and cell-type resolved quantitative proteomic map of the human heart

      Doll, S., Dreßen, M., Geyer, P. E., Itzhak, D. N., Braun, C., Doppler, S. A., Meier, F., Deutsch, M., Lahm, H., Lange, R., Krane, M. & Mann, Matthias, 13 Nov 2017, In: Nature Communications. 8, 1, 13 p., 1469.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      Revisiting biomarker discovery by plasma proteomics

      Geyer, P. E., Holdt, L. M., Teupser, D. & Mann, Matthias, 26 Sep 2017, In: Molecular Systems Biology. 13, 9, 16 p., 942.

      Research output: Contribution to journal › Review › Research › peer-review

    41. Lysine acetylome profiling uncovers novel histone deacetylase substrate proteins in Arabidopsis

      Hartl, M., Füßl, M., Boersema, P. J., Jost, J., Kramer, K., Bakirbas, A., Sindlinger, J., Plöchinger, M., Leister, D., Uhrig, G., Moorhead, G. B., Cox, J., Salvucci, M. E., Schwarzer, D., Mann, Matthias & Finkemeier, I., 2017, In: Molecular Systems Biology. 13, 10, 16 p., 949.

      Research output: Contribution to journal › Journal article › Research › peer-review

    42. Published

      A Primer on Concepts and Applications of Proteomics in Neuroscience

      Hosp, F. & Mann, Matthias, 1 Nov 2017, In: Neuron. 96, 3, p. 558-571 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    43. Lysine acetylation in mitochondria: From inventory to function

      Hosp, F., Lassowskat, I., Santoro, V., De Vleesschauwer, D., Fliegner, D., Redestig, H., Mann, Matthias, Christian, S., Hannah, M. A. & Finkemeier, I., Mar 2017, In: Mitochondrion. 33, p. 58-71 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    44. Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function

      Hosp, F., Gutiérrez-Ángel, S., Schaefer, M. H., Cox, J., Meissner, F., Hipp, M. S., Hartl, F., Klein, R., Dudanova, I. & Mann, Matthias, 21 Nov 2017, In: Cell Reports. 21, 8, p. 2291-2303 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. Phylointeractomics reconstructs functional evolution of protein binding

      Kappei, D., Scheibe, M., Paszkowski-Rogacz, M., Bluhm, A., Gossmann, T. I., Dietz, S., Dejung, M., Herlyn, H., Buchholz, F., Mann, Matthias & Butter, F., 8 Feb 2017, In: Nature Communications. 8, p. 14334

      Research output: Contribution to journal › Journal article › Research › peer-review

    46. Published

      Loss-less Nano-fractionator for High Sensitivity, High Coverage Proteomics

      Kulak, N. A., Geyer, P. E. & Mann, Matthias, Apr 2017, In: Molecular and Cellular Proteomics. 16, 4, p. 694-705 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. A Stat6/Pten Axis Links Regulatory T Cells with Adipose Tissue Function

      Kälin, S., Becker, M., Ott, V. B., Serr, I., Hosp, F., Mollah, M. M. H., Keipert, S., Lamp, D., Rohner-Jeanrenaud, F., Flynn, V. K., Scherm, M. G., Nascimento, L. F. R., Gerlach, K., Popp, V., Dietzen, S., Bopp, T., Krishnamurthy, P., Kaplan, M. H., Serrano, M., Woods, S. C. & 10 others, Tripal, P., Palmisano, R., Jastroch, M., Blüher, M., Wolfrum, C., Weigmann, B., Ziegler, A., Mann, Matthias, Tschöp, M. H. & Daniel, C., 5 Sep 2017, In: Cell Metabolism. 26, 3, p. 475-492.e7

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. Published

      Plenary Lecture Proteomics technologies for signaling, clinical applications

      Mann, Matthias, 2017, p. S62. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    49. Single Muscle Fiber Proteomics Reveals Fiber-Type-Specific Features of Human Muscle Aging

      Murgia, M., Toniolo, L., Nagaraj, N., Ciciliot, S., Vindigni, V., Schiaffino, S., Reggiani, C. & Mann, Matthias, 13 Jun 2017, In: Cell Reports. 19, 11, p. 2396-2409 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Multivalent binding of PWWP2A to H2A.Z regulates mitosis and neural crest differentiation

      Pünzeler, S., Link, S., Wagner, G., Keilhauer, E. C., Kronbeck, N., Spitzer, R. M., Leidescher, S., Markaki, Y., Mentele, E., Regnard, C., Schneider, K., Takahashi, D., Kusakabe, M., Vardabasso, C., Zink, L. M., Straub, T., Bernstein, E., Harata, M., Leonhardt, H., Mann, M. & 2 others, Rupp, R. A. & Hake, S. B., 1 Aug 2017, In: E M B O Journal. 36, 15, p. 2263-2279 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Social network architecture of human immune cells unveiled by quantitative proteomics

      Rieckmann, J. C., Geiger, R., Hornburg, D., Wolf, T., Kveler, K., Jarrossay, D., Sallusto, F., Shen-Orr, S. S., Lanzavecchia, A., Mann, Matthias & Meissner, F., May 2017, In: Nature Immunology. 18, 5, p. 583-593 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Phosphorylation Is a Central Mechanism for Circadian Control of Metabolism and Physiology

      Robles, M. S., Humphrey, S. J. & Mann, Matthias, 10 Jan 2017, In: Cell Metabolism. 25, 1, p. 118-127 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 5650809