Jiri Lukas
Executive Director, Professor
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Ectopic expression of RNF168 and 53BP1 increases mutagenic but not physiological non-homologous end joining
Zong, D., Callén, E., Pegoraro, G., Lukas, Claudia, Lukas, Jiri & Nussenzweig, A., 26 May 2015, In: Nucleic Acids Research. 43, 10, p. 4950-61 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ATR-Chk1-APC/C-dependent stabilization of Cdc7-ASK (Dbf4) kinase is required for DNA lesion bypass under replication stress
Yamada, M., Watanabe, K., Mistrik, M., Vesela, E., Protivankova, I., Mailand, Niels, Lee, M. H., Masai, H., Lukas, Jiri & Bartek, J., 15 Nov 2013, In: Genes & Development. 27, 22, p. 2459-2472 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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JMJD1C demethylates MDC1 to regulate the RNF8 and BRCA1-mediated chromatin response to DNA breaks
Watanabe, S., Watanabe, K., Akimov, V., Bartkova, J., Blagoev, B., Lukas, Jiri & Bartek, J., 17 Nov 2013, In: Nature Structural and Molecular Biology. 20, p. 1425-1433Research output: Contribution to journal › Journal article › Research › peer-review
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ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA
Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Replication Catastrophe: When a Checkpoint Fails because of Exhaustion
Toledo, L., Neelsen, K. J. & Lukas, Jiri, 15 Jun 2017, In: Molecular Cell. 66, 6, p. 735-749 15 p.Research output: Contribution to journal › Review › Research › peer-review
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53BP1 nuclear bodies enforce replication timing at under-replicated DNA to limit heritable DNA damage
Spies, J., Lukas, Claudia, Somyajit, K., Rask, M., Lukas, Jiri & Neelsen, K. J., 2019, In: Nature Cell Biology. 21, p. 487-497Research output: Contribution to journal › Journal article › Research › peer-review
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Homologous recombination as a fundamental genome surveillance mechanism during dna replication
Spies, J., Polasek-Sedlackova, H., Lukas, Jiri & Somyajit, K., 2021, In: Genes. 12, 12, 17 p., 1960.Research output: Contribution to journal › Review › Research › peer-review
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Mammalian RAD52 Functions in Break-Induced Replication Repair of Collapsed DNA Replication Forks
Sotiriou, S. K., Kamileri, I., Lugli, N., Evangelou, K., Da-Ré, C., Huber, F., Padayachy, L., Tardy, S., Nicati, N. L., Barriot, S., Ochs, Fena, Lukas, Claudia, Lukas, Jiri, Gorgoulis, V. G., Scapozza, L. & Halazonetis, T. D., 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1127-1134 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Homology-directed repair protects the replicating genome from metabolic assaults
Somyajit, K., Spies, J., Coscia, F., Kirik, U., Rask, M., Lee, J., Neelsen, K. J., Mund, Andreas, Jensen, Lars Juhl, Paull, T. T., Mann, Matthias & Lukas, Jiri, 2021, In: Developmental Cell. 56, 4, p. 461-477.e7Research output: Contribution to journal › Journal article › Research › peer-review
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Redox-sensitive alteration of replisome architecture safeguards genome integrity
Somyajit, K., Gupta, R., Sedlackova, H., Neelsen, K. J., Ochs, Fena, Rask, M., Choudhary, Chunaram & Lukas, Jiri, 10 Nov 2017, In: Science. 358, 6364, p. 797-802 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Equilibrium between nascent and parental MCM proteins protects replicating genomes
Sedlackova, H., Rask, M., Gupta, R., Choudhary, Chunaram, Somyajit, K. & Lukas, Jiri, 2020, In: Nature. 587, p. 297-302 34 p.Research output: Contribution to journal › Journal article › Research › peer-review
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E2F activity is essential for survival of Myc-overexpressing human cancer cells
Santoni Rugiu, Eric, Duro, D., Farkas, T., Mathiasen, I. S., Jäättelä, M., Bartek, J. & Lukas, Jiri, 2002, In: Oncogene. 21, 42, p. 6498-6509 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Involvement of Myc activity in a G(1)/S-promoting mechanism parallel to the pRb/E2F pathway
Santoni Rugiu, Eric, Falck, J., Mailand, Niels, Bartek, J. & Lukas, Jiri, May 2000, In: Molecular and Cellular Biology. 20, 10, p. 3497-509 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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HCLK2 is required for activity of the DNA damage response kinase ATR
Rendtlew Danielsen, J. M., Larsen, D. H., Schou, K. B., Freire, R., Falck, J., Bartek, J. & Lukas, Jiri, 2008, In: Journal of Biological Chemistry. 284, 7, p. 4140-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes
Polasek-Sedlackova, H., Miller, Thomas, Krejci, J., Rask, M. B. & Lukas, Jiri, 2022, In: Nature Communications. 13, 11 p., 6090.Research output: Contribution to journal › Journal article › Research › peer-review
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Profiling DNA damage response following mitotic perturbations
Pedersen, R. S., Karemore, G., Gudjónsson, Thorkell, Rask, M., Neumann, B., Hériché, J., Pepperkok, R., Ellenberg, J., Gerlich, D. W., Lukas, Jiri & Lukas, Claudia, 15 Dec 2016, In: Nature Communications. 7, 12 p., 13887.Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of candidate biomarkers to predict cancer cell sensitivity or resistance to PARP-1 inhibitor treatment
Oplustilova, L., Wolanin, K., Bartkova, J., Lukas, Jiri, Bartek, J., Lau, A., O'Connor, M. J., Mistrik, M., Korinkova, G., Simkova, D., Bouchal, J. & Lenobel, R., 15 Oct 2012, In: Cell Cycle. 11, 20, p. 3837-3850 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stabilization of chromatin topology safeguards genome integrity
Ochs, Fena, Karemore, G., Miron, E., Brown, J., Sedlackova, H., Rask, M., Lampe, M., Buckle, V., Schermelleh, L., Lukas, Jiri & Lukas, Claudia, 2019, In: Nature. 574, 7779, p. 571-574 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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53BP1 fosters fidelity of homology-directed DNA repair
Ochs, Fena, Somyajit, K., Altmeyer, M., Rask, M. D., Lukas, Jiri & Lukas, Claudia, Aug 2016, In: Nature Structural and Molecular Biology. 23, 8, p. 714-21 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity
Moudry, P., Watanabe, K., Wolanin, K. M., Bartkova, J., Wassing, I. E., Watanabe, S., Strauss, R., Pedersen, R. T., Østergaard, Vibe Hallundbæk, Lisby, Michael, Andújar-Sánchez, M., Maya-Mendoza, A., Esashi, F., Lukas, Jiri & Bartek, J., 2016, In: The Journal of Cell Biology. 212, 3, p. 281-288 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ubiquitin-activating enzyme UBA1 is required for cellular response to DNA damage
Moudry, P., Lukas, Claudia, Macurek, L., Hanzlikova, H., Hodny, Z., Lukas, Jiri & Bartek, J., 15 Apr 2012, In: Cell Cycle. 11, 8, p. 1573-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Low-dose DNA damage and replication stress responses quantified by optimized automated single-cell image analysis
Mistrik, M., Oplustilova, L., Lukas, Jiri & Bartek, J., 2009, In: Cell Cycle. 8, 16, p. 2592-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin
Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response
Marteijn, J. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, Jiri & Vermeulen, W., 2009, In: Journal of Cell Biology. 186, 6, p. 835-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Destruction of Claspin by SCFbetaTrCP restrains Chk1 activation and facilitates recovery from genotoxic stress
Mailand, Niels, Bekker-Jensen, Simon Holst, Bartek, J. & Lukas, Jiri, 2006, In: Molecular Cell. 23, 3, p. 307-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Deregulated human Cdc14A phosphatase disrupts centrosome separation and chromosome segregation
Mailand, Niels, Lukas, Claudia, Kaiser, B. K., Jackson, P. K., Bartek, J. & Lukas, Jiri, Apr 2002, In: Nature Cell Biology. 4, 4, p. 317-22 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins
Mailand, Niels, Bekker-Jensen, Simon Holst, Faustrup, H., Melander, F., Bartek, J., Lukas, Claudia & Lukas, Jiri, 2007, In: Cell. 131, 5, p. 887-900 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability.
Mailand, Niels, Podtelejnikov, A. V., Groth, Anja, Mann, M., Bartek, J. & Lukas, Jiri, 2002, In: EMBO Journal. 21, 21, p. 5911-20 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Rapid destruction of human Cdc25A in response to DNA damage
Mailand, Niels, Falck, J., Lukas, Claudia, Syljuåsen, R. G., Welcker, M., Bartek, J. & Lukas, Jiri, 26 May 2000, In: Science (New York, N.Y.). 288, 5470, p. 1425-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Immunoprecipitation of Proteins under Nondenaturing Conditions
Lukas, Jiri, Bartek, J. & Hansen, K., 1 Dec 2006, Cell Biology, Four-Volume Set. Elsevier Science Inc., Vol. 4. p. 253-258 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Jiri Lukas: Visualizing genome integrity maintenance. Interview by Caitlin Sedwick
Lukas, Jiri, 9 Jul 2012, In: Journal of Cell Biology. 198, 1, p. 4-5 2 p.Research output: Contribution to journal › Journal article › Communication
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A lncRNA to repair DNA
Lukas, Jiri & Altmeyer, M., 2015, In: E M B O Reports. 16, 11, p. 1413-1414 2 p.Research output: Contribution to journal › Comment/debate › Research
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DNA repair: New tales of an old tail
Lukas, Jiri & Bartek, J., 2009, In: Nature. 458, 7238, p. 581-3 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Shielding broken DNA for a quick fix
Lukas, Jiri & Lukas, Claudia, 8 Feb 2013, In: Science. 339, 6120, p. 652-653 2 p.Research output: Contribution to journal › Review › Research › peer-review
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53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
DNA damage-activated kinase Chk2 is independent of proliferation or differentiation yet correlates with tissue biology
Lukas, Claudia, Bartkova, J., Latella, L., Falck, J., Mailand, Niels, Schroeder, T., Sehested, M., Lukas, Jiri & Bartek, J., 1 Jul 2001, In: Cancer Research. 61, 13, p. 4990-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Claspin operates downstream of TopBP1 to direct ATR signaling towards Chk1 activation
Liu, S., Bekker-Jensen, Simon Holst, Mailand, Niels, Lukas, Claudia, Bartek, J. & Lukas, Jiri, 2006, In: Molecular and Cellular Biology. 26, 16, p. 6056-64 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage
Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, L. I., Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In: Nature Cell Biology. 16, 8, p. 792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Centrosome-associated Chk1 prevents premature activation of cyclin-B-Cdk1 kinase
Krämer, A., Mailand, Niels, Lukas, Claudia, Syljuåsen, R. G., Wilkinson, C. J., Nigg, E. A., Bartek, J. & Lukas, Jiri, Sep 2004, In: Nature Cell Biology. 6, 9, p. 884-91 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses
Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 272-285 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Autocrine VEGF-VEGFR2-Neuropilin-1 signaling promotes glioma stem-like cell viability and tumor growth
Hamerlik, P., Lathia, J. D., Rasmussen, R., Wu, Q., Bartkova, J., Lee, M., Moudry, P., Bartek, J., Fischer, W., Lukas, Jiri, Rich, J. N. & Bartek, J., 12 Mar 2012, In: The Journal of Experimental Medicine. 209, 3, p. 507-20 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity
Gupta, R., Somyajit, K., Narita, Takeo, Maskey, E., Stanlie, A., Kremer, M., Typas, D., Lammers, M., Mailand, Niels, Nussenzweig, A., Lukas, Jiri & Choudhary, Chunaram, 2018, In: Cell. 173, 4, p. 972-988Research output: Contribution to journal › Journal article › Research › peer-review
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TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.
Groth, Anja, Lukas, Jiri, Nigg, E., Silljé, H., Wernstedt, C., Bartek, J. & Hansen, K., Apr 2003, In: The EMBO Journal. 22, 7, p. 1676-1687Research output: Contribution to journal › Journal article › Research › peer-review
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., Georgakilas, A. G., Geacintov, N., Scorrano, L., Lukas, C., Lukas, J., Livneh, Z., Lygerou, Z., Chowdhury, D., Sørensen, C. S., Bartek, J. & 1 others, , 2018, In: Genome Biology (Online Edition). 19, p. 1-18 37.Research output: Contribution to journal › Journal article › Research › peer-review
Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities
Fugger, K., Mistrik, M., Danielsen, J. R., Dinant, C., Falck, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 186, 5, p. 655-63 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin
Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
CDK targeting of NBS1 promotes DNA-end resection, replication restart and homologous recombination
Falck, J., Forment, J. V., Coates, J., Mistrik, M., Lukas, Jiri, Bartek, J. & Jackson, S. P., Jun 2012, In: E M B O Reports. 13, 6, p. 561-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
Falck, J., Mailand, Niels, Syljuåsen, R. G., Bartek, J. & Lukas, Jiri, 12 Apr 2001, In: Nature. 410, 6830, p. 842-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis
Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., Kosar, M., Liloglou, T., Trougakos, I. P., Dyrskjot, L., Andersen, C. L., Papaioannou, M., Drosos, Y., Papafotiou, G., Hodny, Z., Sosa-Pineda, B., Wu, X-R., Klinakis, A., Ørntoft, T. F., Lukas, J. & 2 others, , 1 Nov 2013, In: Cell Death and Differentiation. 20, 11, p. 1485-1497 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Ercilla, A., Benada, Jan, Gadi, Sampath Amitash, Zonderland, Gijs, Baldi, G., Somyajit, K., Ochs, Fena, Costanzo, V., Lukas, Jiri & Toledo, L., 2020, In: Cell Reports. 30, 7, p. 2416-2429.e7 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins
Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LEDGF (p75) promotes DNA-end resection and homologous recombination
Daugaard, M., Baude, A., Fugger, K., Povlsen, L. K., Beck, H., Sørensen, Claus Storgaard, Petersen, N. H. T., Sorensen, P. H. B., Lukas, Claudia, Bartek, J., Lukas, Jiri, Rohde, M. & Jaattela, Marja, Aug 2012, In: Nature Structural & Molecular Biology. 19, 8, p. 803-810 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrating proteomic and functional genomic technologies in discovery-driven translational breast cancer research
Celis, J. E., Gromov, P., Gromova, I., Moreira, J. M. A., Cabezón, T., Ambartsumian, N., Grigorian, M., Lukanidin, E., Thor Straten, P., Guldberg, P., Bartkova, J., Bartek, J., Lukas, J., Lukas, C., Lykkesfeldt, A., Jäättelä, M., Roepstorff, P., Bolund, L., Ørntoft, T. F., Brünner, N. & 5 others, , 2003, In: Molecular and Cellular Proteomics. 2, 6, p. 369-377 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection
Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In: EMBO Journal. 28, 6, p. 652-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA damage-induced dynamic changes in abundance and cytosol-nuclear translocation of proteins involved in translational processes, metabolism, and autophagy
Bennetzen, M. V., Kosar, M., Bunkenborg, J., Payne, M. R., Bartkova, J., Lindström, M. S., Lukas, Jiri, Andersen, J. S., Bartek, J. & Larsen, D. H., 2018, In: Cell Cycle. 17, 17, p. 2146-2163Research output: Contribution to journal › Journal article › Research › peer-review
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Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response
Bennetzen, M., Andersen, J. S., Lasen, D. H., Dinant, C., Watanabe, S., Bartek, J. & Lukas, Jiri, 1 Jun 2013, In: Cell Cycle. 12, 11, p. 1688-1695 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes
Bekker-Jensen, Simon Holst, Danielsen, J. M. R., Fugger, K., Gromova, I., Nerstedt, A., Bartek, J., Lukas, Jiri & Mailand, Niels, 2010, In: Nature Cell Biology. 12, 1, p. 80-6; sup pp 1-12Research output: Contribution to journal › Letter › Research › peer-review
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Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks
Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
Bartkova, J., Horejsí, Z., Koed, K., Krämer, A., Tort, F., Zieger, K., Guldberg, P., Sehested, M., Nesland, J. M., Lukas, Claudia, Ørntoft, T., Lukas, Jiri & Bartek, J., 14 Apr 2005, In: Nature. 434, 7035, p. 864-70 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In: Nature Communications. 6, p. 1-12 8088.Research output: Contribution to journal › Journal article › Research › peer-review
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Guarding against Collateral Damage during Chromatin Transactions
Altmeyer, M. & Lukas, Jiri, 20 Jun 2013, In: Cell. 153, 7, p. 1431-4 4 p.Research output: Contribution to journal › Review › Research › peer-review
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The Chromatin Scaffold Protein SAFB1 Renders Chromatin Permissive for DNA Damage Signaling
Altmeyer, M., Toledo Lazaro, L. I., Gudjónsson, Thorkell, Grøfte, M., Rask, M., Lukas, Claudia, Akimov, V., Blagoev, B., Bartek, J. & Lukas, Jiri, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 206-220Research output: Contribution to journal › Journal article › Research › peer-review
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To spread or not to spread - chromatin modifications in response to DNA damage
Altmeyer, M. & Lukas, Jiri, 9 Jan 2013, In: Current Opinion in Genetics & Development. 23, 2, p. 156-165 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37762642
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TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity
Research output: Contribution to journal › Journal article › Research › peer-review
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175
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Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability
Research output: Contribution to journal › Journal article › Research › peer-review
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156
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Physiological Tolerance to ssDNA Enables Strand Uncoupling during DNA Replication
Research output: Contribution to journal › Journal article › Research › peer-review
Published