Jesper Velgaard Olsen

Jesper Velgaard Olsen

Professor, Deputy Head of Centre, Professor

Member of:


    1. 2023
    2. Published

      Optimizing Linear Ion-Trap Data-Independent Acquisition toward Single-Cell Proteomics

      Phlairaharn, T., Ye, Z., Krismer, Elena, Pedersen, A. K., Pietzner, M., Olsen, Jesper Velgaard, Schoof, E. M. & Searle, B. C., 2023, In: Analytical Chemistry. 95, 26, p. 9881-9891 11 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    3. Published

      Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1

      Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.

      Research output: Contribution to journalJournal articleResearchpeer-review

    4. Published

      ROS-induced ribosome impairment underlies ZAKα-mediated metabolic decline in obesity and aging

      Snieckute, G., Ryder, L., Vind, A. C., Wu, Z., Arendrup, F. S., Stoneley, M., Chamois, S., Martinez-Val, A., Leleu, M., Dreos, R., Russell, A., Gay, D. M., Genzor, A. V., Choi, B. S-Y., Basse, A. L., Sass, F., Dall, M., Dollet, L. C. M., Blasius, M., Willis, A. E. & 10 others, Lund, Anders H., Treebak, Jonas Thue, Olsen, Jesper Velgaard, Poulsen, Steen Seier, Pownall, M. E., Jensen, Benjamin Anderschou Holbech, Clemmensen, Christoffer, Gerhart-Hines, Zach, Gatfield, D. & Bekker-Jensen, Simon Holst, 2023, In: Science (New York, N.Y.). 382, 6675, 14 p., eadf3208.

      Research output: Contribution to journalJournal articleResearchpeer-review

    5. Published

      GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics

      Wright, S. C., Motso, A., Koutsilieri, S., Beusch, C. M., Sabatier, Pierre Camille, Berghella, A., Blondel-Tepaz, É., Mangenot, K., Pittarokoilis, I., Sismanoglou, D. C., Le Gouill, C., Olsen, Jesper Velgaard, Zubarev, R. A., Lambert, N. A., Hauser, Alexander Sebastian, Bouvier, M. & Lauschke, V. M., 2023, In: Nature Communications. 14, 1, 13 p., 6243.

      Research output: Contribution to journalJournal articleResearchpeer-review

    6. 2022
    7. Published

      A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos

      Demeter, F., Zanolli, C., Westaway, K. E., Joannes-Boyau, R., Duringer, P., Morley, M. W., Welker, F., Rüther, P. L., Skinner, M. M., McColl, H., Gaunitz, C., Vinner, L., Dunn, T. E., Olsen, J. V., Sikora, M., Ponche, J-L., Suzzoni, E., Frangeul, S., Boesch, Q., Antoine, P-O. & 20 others, Pan, L., Xing, S., Zhao, J., Bailey, R. M., Boualaphane, S., Sichanthongtip, P., Sihanam, D., Patole-Edoumba, E., Aubaile, F., Crozier, F., Bourgon, N., Zachwieja, A., Luangkhoth, T., Souksavatdy, V., Sayavongkhamdy, T., Cappellini, Enrico, Bacon, A., Hublin, J., Willerslev, Eske & Shackelford, L., 2022, In: Nature Communications. 13, 17 p., 2557.

      Research output: Contribution to journalJournal articleResearchpeer-review

    8. Published

      Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance

      Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.

      Research output: Contribution to journalJournal articleResearchpeer-review

    9. Published

      THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1

      Kamp, J. A., Lemmens, B. B. L. G., Romeijn, R. J., González-Prieto, R., Olsen, Jesper Velgaard, Vertegaal, A. C. O., van Schendel, R. & Tijsterman, M., 2022, In: Nucleic Acids Research. 50, 11, p. 6235-6250 16 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    10. Published

      Optimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing

      Koenig, Claire, Martinez-Val, A., Franciosa, Giulia & Olsen, Jesper Velgaard, 2022, In: Proteomics. 22, 19-20, 13 p., 2100245.

      Research output: Contribution to journalJournal articleResearchpeer-review

    11. Published

      Combining mass spectrometry and machine learning to discover bioactive peptides

      Madsen, C. T., Refsgaard, J. C., Teufel, F. G., Kjærulff, S. K., Wang, Z., Meng, G., Jessen, C., Heljo, P., Jiang, Q., Zhao, X., Wu, B., Zhou, X., Tang, Y., Jeppesen, J. F., Kelstrup, C. D., Buckley, S. T., Tullin, S., Nygaard-Jensen, J., Chen, X., Zhang, F. & 4 others, Olsen, Jesper Velgaard, Han, D., Grønborg, M. & de Lichtenberg, U., 2022, In: Nature Communications. 13, 17 p., 6235.

      Research output: Contribution to journalJournal articleResearchpeer-review

    12. Published

      The feasibility of palaeoproteomics for studying ancient hominins from South Africa

      Madupe, Palesa Petunia, Hlazo, N., Ruther, P. L., Mackie, Meaghan, Welker, Frido, Ramos Madrigal, Jazmin, Patramanis, Ioannis, Racimo, Fernando, Schroeder, L., Olsen, Jesper Velgaard, Ackermann, R. R. & Cappellini, Enrico, 2022, In: American journal of biological anthropology. 177, S73, p. 112 1 p.

      Research output: Contribution to journalConference abstract in journalResearchpeer-review

    13. Published

      Obtaining Complete Human Proteomes

      Martinez Del Val, Ana, Hernández Guzmán, Ulises & Olsen, Jesper Velgaard, 2022, In: Annual Review of Genomics and Human Genetics. 23, p. 10.1-10.23 23 p.

      Research output: Contribution to journalReviewResearchpeer-review

    14. Published

      ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

      Nordgaard, C., Vind, A. C., Stonadge, A., Kjøbsted, R., Snieckute, G., Antas, P., Blasius, M., Reinert, M. S., Del Val, A. M., Bekker-Jensen, D. B., Haahr, P., Miroshnikova, Y. A., Mazouzi, A., Falk, S., Perrier-Groult, E., Tiedje, C., Li, X., Jakobsen, J. R., Jørgensen, N. O., Wojtaszewski, J. & 12 others, Mallein-Gerin, F., Andersen, J. L., Pennisi, C. P., Clemmensen, Christoffer, Kassem, Moustapha Saad El-Deen, Jafari Kermani, Abbas, Brummelkamp, T., Li, V. S., Wickström, S. A., Olsen, Jesper Velgaard, Blanco, G. & Bekker-Jensen, Simon Holst, 2022, In: E M B O Journal. 41, 17, 19 p., e111650.

      Research output: Contribution to journalJournal articleResearchpeer-review

    15. Published

      Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML

      Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    16. Published

      Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology

      Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, Aznar, S., 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.

      Research output: Contribution to journalJournal articleResearchpeer-review

    17. Published

      SPIN enables high throughput species identification of archaeological bone by proteomics

      Rüther, P. L., Husic, I. M., Bangsgaard, Pernille, Gregersen, K. M., Pantmann, P., Carvalho, M., Godinho, R. M., Friedl, L., Cascalheira, J., Taurozzi, Alberto John, Jørkov, M L S, Benedetti, M. M., Haws, J., Bicho, N., Welker, Frido, Cappellini, Enrico & Olsen, Jesper Velgaard, 2022, In: Nature Communications. 13, 14 p., 2458.

      Research output: Contribution to journalJournal articleResearchpeer-review

    18. Published

      Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation

      Sampadi, B., Vermeulen, S., Mišovic, B., Boei, J. J., Batth, Tanveer Singh, Chang, J. G., Paulsen, M. T., Magnuson, B., Schimmel, J., Kool, H., Olie, C. S., Everts, B., Vertegaal, A. C. O., Olsen, Jesper Velgaard, Ljungman, M., Jeggo, P. A., Mullenders, L. H. F. & Vrieling, H., 2022, In: Cells. 11, 23, 25 p., 3794.

      Research output: Contribution to journalJournal articleResearchpeer-review

    19. Published

      Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)

      Scorrano, Gabriele, Nielsen, Sofie Holtsmark, Vetro, D. L., Sawafuji, R., Mackie, Meaghan, Margaryan, Ashot, Fotaki, Anna Katerina, Martínez-Labarga, C., Fabbri, P. F., Allentoft, Morten Erik, Carra, M., Martini, F., Rickards, O., Olsen, Jesper Velgaard, Pedersen, Mikkel Winther, Cappellini, Enrico & Sikora, Martin, 2022, In: Communications Biology. 5

      Research output: Contribution to journalJournal articleResearchpeer-review

    20. Published

      A deeper look at carrier proteome effects for single-cell proteomics

      Ye, Z., Batth, Tanveer Singh, Rüther, P. & Olsen, Jesper Velgaard, 2022, In: Communications Biology . 5, 8 p., 150.

      Research output: Contribution to journalJournal articleResearchpeer-review

    21. Published

      Characterization of TGF-β signaling in a human organotypic skin model reveals that loss of TGF-βRII induces invasive tissue growth

      Ye, Z., Kilic, G., Dabelsteen, Sally, Marinova, I. N., Thøfner, J. F. B., Song, Ming, Levann, Asha Maria Rudjord, Bagdonaite, Ieva , Vakhrushev, Sergey, Brakebusch, Cord Herbert, Olsen, Jesper Velgaard & Wandall, Hans H., 2022, In: Science Signaling. 15, 761, eabo2206.

      Research output: Contribution to journalJournal articleResearchpeer-review

    22. 2021
    23. Published

      The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes

      Davydova, E., Shimazu, T., Schuhmacher, M. K., Jakobsson, M. E., Willemen, H. L. D. M., Liu, T., Moen, A., Ho, A. Y. Y., Małecki, J., Schroer, L., Pinto, R., Suzuki, T., Grønsberg, I. A., Sohtome, Y., Akakabe, M., Weirich, S., Kikuchi, M., Olsen, J. V., Dohmae, N., Umehara, T. & 8 others, Sodeoka, M., Siino, V., McDonough, M. A., Eijkelkamp, N., Schofield, C. J., Jeltsch, A., Shinkai, Y. & Falnes, P., 2021, In: Nature Communications. 12, 14 p., 891.

      Research output: Contribution to journalJournal articleResearchpeer-review

    24. Published

      Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses

      Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.

      Research output: Contribution to journalJournal articleResearchpeer-review

    25. Published

      Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures

      Franciosa, Giulia, Smits, J. G. A., Minuzzo, S., Martinez Del Val, Ana, Indraccolo, S. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 19 p., 2507.

      Research output: Contribution to journalJournal articleResearchpeer-review

    26. Published

      FRMD6 has tumor suppressor functions in prostate cancer

      Haldrup, J., Strand, S. H., Cieza-Borrella, C., Jakobsson, M. E., Riedel, M., Norgaard, M., Hedensted, S., Dagnaes-Hansen, F., Ulhoi, B. P., Eeles, R., Borre, M., Olsen, Jesper Velgaard, Thomsen, M., Kote-Jarai, Z. & Sorensen, K. D., 2021, In: Oncogene. 40, p. 763-776 14 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    27. Published

      Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication

      Jones, M. J. K., Gelot, C., Munk, S., Koren, A., Kawasoe, Y., George, K. A., Santos, R. E., Olsen, Jesper Velgaard, McCarroll, S. A., Frattini, M. G., Takahashi, T. S. & Jallepalli, P. V., 2021, In: Molecular Cell. 81, 3, p. 426-441.e8 24 p.

      Research output: Contribution to journalJournal articleResearchpeer-review

    28. Published

      GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain

      Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, Chi, C. C., Gee, C. L., Frølund, Bente, Kornum, Birgitte Rahbek, van Woerden, G. M., Clausen, Rasmus Prætorius, Kuriyan, J., Clarkson, A. N. & Wellendorph, Petrine, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.

      Research output: Contribution to journalJournal articleResearchpeer-review

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    ID: 9925376