Jakob Nilsson
Professor
Nilsson Group
Blegdamsvej 3B
2200 København N
- 2008
The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction
Nilsson, Jakob, Yekezare, M., Minshull, J. & Pines, J., 2008, In: Nature Cell Biology. 10, 12, p. 1411-20 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Cdc20 control of cell fate during prolonged mitotic arrest: do Cdc20 protein levels affect cell fate in response to antimitotic compounds?
Nilsson, Jakob, 2011, In: BioEssays. 33, 12, p. 903-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure of a Blinkin-BUBR1 complex reveals an interaction crucial for kinetochore-mitotic checkpoint regulation via an unanticipated binding Site
Bolanos-Garcia, V. M., Lischetti, T., Matak-Vinković, D., Cota, E., Simpson, P. J., Chirgadze, D. Y., Spring, D. R., Robinson, C. V., Nilsson, Jakob & Blundell, T. L., 9 Nov 2011, In: Structure. 19, 11, p. 1691-700 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ndc80 internal loop is required for recruitment of the Ska complex to establish end-on microtubule attachment to kinetochores
Zhang, G., Kelstrup, C. D., Hu, X., Hansen, M. J. K., Singleton, M. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2012, In: Journal of Cell Science. p. 3243-3253 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The architecture of the BubR1 tetratricopeptide tandem repeat defines a protein motif underlying mitotic checkpoint-kinetochore communication
Bolanos-Garcia, V. M., Nilsson, Jakob & Blundell, T. L., 1 Jan 2012, In: Bioarchitecture. 2, 1, p. 23-27 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Looping in on Ndc80 - how does a protein loop at the kinetochore control chromosome segregation?
Nilsson, Jakob, Dec 2012, In: BioEssays. 34, 12, p. 1070-7 8 p.Research output: Contribution to journal › Review › Research › peer-review
- 2013
- Published
Transcriptional intermediary factor 1γ binds to the anaphase-promoting complex/cyclosome and promotes mitosis
Sedgwick, G. G., Townsend, K., Martin, A., Shimwell, N. J., Grand, R. J. A., Stewart, G. S., Nilsson, Jakob & Turnell, A. S., 2013, In: Oncogene. 32, 39, p. 4622-4633 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct binding between BubR1 and B56-PP2A phosphatase complexes regulate mitotic progression
Kruse, Thomas, Zhang, G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Nielsen, T. K., Bjørn, S. P. & Nilsson, Jakob, 23 Jan 2013, In: Journal of Cell Science. 126, p. 1086-1092 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanisms controlling the temporal degradation of Nek2A and Kif18A by the APC/C-Cdc20 complex
Sedgwick, G. G., Hayward, D. G., Nilsson, Jakob, Di Fiore, B., Pines, J., Pardo, M. & Yu, L., 23 Jan 2013, In: E M B O Journal. 32, 2, p. 303-314 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Drosophila Microtubule-Associated Protein Mars Stabilizes Mitotic Spindles by Crosslinking Microtubules through Its N-Terminal Region
Zhang, G., Beati, H., Nilsson, Jakob & Wodarz, A., 4 Apr 2013, In: P L o S One. 8, 4, p. e60596 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A minimal number of MELT repeats supports all functions of KNL1 in chromosome segregation
Zhang, G., Lischetti, T. & Nilsson, Jakob, 20 Dec 2013, In: Journal of Cell Science. 127, p. 871-884Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint
Hein, J. B. & Nilsson, Jakob, 25 Jan 2014, In: E M B O Reports. 15, p. 264-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A direct role of Mad1 in the spindle assembly checkpoint beyond Mad2 kinetochore recruitment
Kruse, Thomas, Larsen, Marie Sofie Yoo, Sedgwick, G. G., Sigurdsson, J. O., Streicher, W., Olsen, Jesper Velgaard & Nilsson, Jakob, 29 Jan 2014, In: E M B O Reports. 15, p. 282-290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The internal Cdc20 binding site in BubR1 facilitates both spindle assembly checkpoint signalling and silencing
Lischetti, T., Zhang, G., Sedgwick, G. G., Bolanos-Garcia, V. M. & Nilsson, Jakob, Dec 2014, In: Nature Communications. 5, p. 1-12 12 p., 5563.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Regulation of mitotic progression by the spindle assembly checkpoint
Lischetti, T. & Nilsson, Jakob, 2015, In: Molecular & Cellular Oncology. 2, 1, e970484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TopBP1 is required at mitosis to reduce transmission of DNA damage to G1 daughter cells
Pedersen, R. T., Kruse, Thomas, Nilsson, Jakob, Østergaard, Vibe Hallundbæk & Lisby, Michael, 2015, In: Journal of Cell Biology. 210, 4, p. 565-582 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Can sequestering of mitotic spindle proteins cause aneuploidy? (Comment on DOI 10.1002/bies.201400175)
Nilsson, Jakob, Mar 2015, In: BioEssays. 37, 3, p. 234 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint
Zhang, G., Lischetti, T., Hayward, D. G. & Nilsson, Jakob, 2 Jun 2015, In: Nature Communications. 6, 14 p., 7162.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mps1-Ndc80: one interaction to rule them all
Nilsson, Jakob, 10 Jun 2015, In: OncoTarget. 6, 19, p. 16822–16823 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Bub1/BubR1: swiss army knives at kinetochores
Nilsson, Jakob, 11 Aug 2015, In: Cell Cycle. 14, 9, p. 2999-3000 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
- 2016
- Published
A Conserved Motif Provides Binding Specificity to the PP2A-B56 Phosphatase
Hertz, Emil Peter Thrane, Kruse, Thomas, Davey, N. E., López-Méndez, B., Sigurdsson, J. O., Montoya, Guillermo, Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: Molecular Cell. 63, 4, p. 686-695 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conformation-specific anti-Mad2 monoclonal antibodies for the dissection of checkpoint signaling
Sedgwick, G. G., Larsen, Marie Sofie Yoo, Lischetti, T., Streicher, W., Jersie-Christensen, R. R., Olsen, Jesper Velgaard & Nilsson, Jakob, 2016, In: mAbs. 8, 4, p. 689-697 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two functionally distinct kinetochore pools of BubR1 ensure accurate chromosome segregation
Zhang, G., Mendez, B. L., Sedgwick, G. G. & Nilsson, Jakob, 2016, In: Nature Communications. 7, p. 1-12 12 p., 12256.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8799501
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Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanisms of site-specific dephosphorylation and kinase opposition imposed by PP2A regulatory subunits
Research output: Contribution to journal › Journal article › Research › peer-review
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118
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A dynamic charge-charge interaction modulates PP2A:B56 substrate recruitment
Research output: Contribution to journal › Journal article › Research › peer-review
Published