Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor


  1. 2017
  2. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Electron Microscopy Structural Insights into CPAP Oligomeric Behavior: A Plausible Assembly Process of a Supramolecular Scaffold of the Centrosome

    Alvarez-Cabrera, A. L., Delgado, S., Gil-Carton, D., Mortuza, G. B., Montoya, Guillermo, Sorzano, C. O. S., Tang, T. K. & Carazo, J. M., 2017, In: Frontiers in Molecular Biosciences. 4, 14 p., 17.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Structure of the Cpf1 endonuclease R-loop complex after target DNA cleavage

    Stella, S., Alcón, P. & Montoya, Guillermo, 22 Jun 2017, In: Nature. 546, 7659, p. 559-563 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  5. Published

    Assembly of Francisella novicida Cpf1 endonuclease in complex with guide RNA and target DNA

    Alcón, P., Montoya, Guillermo & Stella, S., 1 Jul 2017, In: Acta Crystallographica Section F: Structural Biology Communications. 73, Pt 7, p. 409-415 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Allosteric regulation of Csx1, a type IIIB-associated CARF domain ribonuclease by RNAs carrying a tetraadenylate tail

    Han, W., Pan, S., López-Méndez, B., Montoya, Guillermo & She, Q., 13 Oct 2017, In: Nucleic Acids Research. 45, 18, p. 10740-10750 11 p., gkx726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Class 2 CRISPR-Cas RNA-guided endonucleases: Swiss Army knives of genome editing

    Stella, S., Alcón, P. & Montoya, Guillermo, Nov 2017, In: Nature Structural and Molecular Biology. 24, 11, p. 882-892 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Structure and dynamics of mesophilic variants from the homing endonuclease I-DmoI

    Alba, J., Marcaida, M. J., Prieto, J., Montoya, Guillermo, Molina, R. & D'Abramo, M., Dec 2017, In: Journal of Computer - Aided Molecular Design. 31, 12, p. 1063-1072 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2018
  10. Published

    A Type III-B Cmr effector complex catalyzes the synthesis of cyclic oligoadenylate second messengers by cooperative substrate binding

    Han, W., Stella, S., Zhang, Y., Guo, T., Sulek, K., Peng-Lundgren, L., Montoya, Guillermo & She, Q., 2018, In: Nucleic Acids Research. 46, 19, p. 10319-10330 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    How do CRISPR-Cas RNA-guided endonucleases cut specific DNA regions for Genome Editing?

    Montoya, Guillermo, 2018, In: Acta Crystallographica Section A: Foundations and Advances. 74, p. E3 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  12. Published

    Molecular basis of Tousled-Like Kinase 2 activation

    Mortuza, G. B., Hermida, D., Pedersen, Anna-Kathrine, Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Understanding the indirect DNA read-out specificity of I-CreI Meganuclease

    Prieto, J., Redondo, P., López-Méndez, B., D'Abramo, M., Merino, N., Blanco, F. J., Duchateau, P., Montoya, Guillermo & Molina, R., 2018, In: Scientific Reports. 8, p. 1-9 10286.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Conformational Activation Promotes CRISPR-Cas12a Catalysis and Resetting of the Endonuclease Activity

    Stella, S., Mesa, Pablo, Thomsen, J., Paul, B., Alcón, P., Jensen, S. B., Saligram, B., Moses, M. E., Hatzakis, Nikos & Montoya, Guillermo, 13 Dec 2018, In: Cell. 175, 7, p. 1856-1871.e21 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2019
  16. Published

    A Consensus Binding Motif for the PP4 Protein Phosphatase

    Ueki, Y., Kruse, Thomas, Weisser, Melanie, Sundell, G. N., Larsen, Marie Sofie Yoo, Mendez, B. L., Jenkins, N. P., Garvanska, Dimitriya Hristoforova, Cressey, L., Zhang, G., Davey, N., Montoya, Guillermo, Ivarsson, Y., Kettenbach, A. N. & Nilsson, Jakob, 2019, In: Molecular Cell. 76, 6, p. 953-964.e6

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    High-Resolution Structure of Cas13b and Biochemical Characterization of RNA Targeting and Cleavage

    Slaymaker, I. M., Mesa, Pablo, Kellner, M. J., Kannan, S., Brignole, E., Koob, J., Feliciano, P. R., Stella, S., Abudayyeh, O. O., Gootenberg, J. S., Strecker, J., Montoya, Guillermo & Zhang, F., 2019, In: Cell Reports. 26, 13, p. 3741-3751.e5 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Molecular architecture of the Jumonji C family histone demethylase KDM5B

    Dorosz, J., Kristensen, L. H., Aduri, N. G., Mirza, Osman Asghar, Lousen, R., Bucciarelli, S., Mehta, V., Sellés Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, P. A., Montoya, Guillermo, Nguyen, T. T. T. N., Rand, Kasper Dyrberg, Boesen, T. & Gajhede, Michael, 2019, In: Scientific Reports. 9, 13 p., 4019.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

    Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

    Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. 2020
  22. Published

    CRISPR-Cas12a: functional overview and applications

    Paul, B. & Montoya, Guillermo, 2020, In: Biomedical Journal. 43, 1, p. 8-17

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Editorial overview: Protein-nucleic acid interactions: 'Takes two to Tango'

    Montoya, Guillermo & Carlomagno, T., 2020, In: Current Opinion in Structural Biology. 65, p. v-vi 2 p.

    Research output: Contribution to journalEditorialResearch

  24. Published

    Molecular Basis of the Mechanisms Controlling MASTL

    Hermida, D., Mortuza, G. B., Pedersen, Anna-Kathrine, Pozdnyakova, I., Nguyen, T. T. T. N., Maroto, M., Williamson, M., Ebersole, T., Cazzamali, G., Rand, Kasper Dyrberg, Olsen, Jesper Velgaard, Malumbres, M. & Montoya, Guillermo, 2020, In: Molecular & Cellular Proteomics. 19, 2, p. 326-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structural basis of CRISPR-Cas Type III prokaryotic defence systems

    Molina, R., Sofos, N. & Montoya, Guillermo, 2020, In: Current Opinion in Structural Biology. 65, p. 119-129 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Structures of the Cmr-β Complex Reveal the Regulation of the Immunity Mechanism of Type III-B CRISPR-Cas

    Sofos, N., Feng, M., Stella, S., Pape, T., Fuglsang, Anders, Lin, Jinzhong, Huang, Q., Li, Y., She, Q. & Montoya, Guillermo, 2020, In: Molecular Cell. 79, 5, p. 741-757

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The TRiC/CCT Chaperonin and Its Role in Uncontrolled Proliferation

    Wang, D. Y., Kamuda, K., Montoya, Guillermo & Mesa, Pablo, 2020, HSF1 and Molecular Chaperones in Biology and Cancer. Mendillo, M. L., Pincus, D. & ScherzShouval, R. (eds.). Springer, p. 21-40 20 p. (Advances in Experimental Medicine and Biology, Vol. 1243).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  28. Published

    Direct Observation of CRISPR-Cas12 Conformational Sampling by SM FRET and Cryo EM Reveals how Conformational Activation Promotes Catalysis and Resetting of the Endonuclease Activity

    Stella, S., Mesa, Pablo, Thomsen, J., Paul, B., Alcon, P., Jensen, S. B., Moses, M. E., Montoya, Guillermo & Hatzakis, Nikos, 7 Feb 2020, In: Biophysical Journal. 118, 3, p. 223A-224A 2 p.

    Research output: Contribution to journalConference abstract in journalResearch

  29. Published

    DeepFRET, a software for rapid and automated single-molecule FRET data classification using deep learning

    Thomsen, J., Sletfjerding, M. B., Jensen, S. B., Stella, S., Paul, B., Malle, M. G., Montoya, Guillermo, Petersen, Troels Christian & Hatzakis, Nikos, Nov 2020, In: eLife. 9, 21 p., e60404.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 93716435