Guillermo Montoya

Guillermo Montoya

Professor, head of research, Professor

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    ORCID: 0000-0002-8269-3941

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    1. Molecular scissors for in situ cellular repair

      Prieto, J., Molina, R. & Montoya, Guillermo, 31 Jan 2012, In: Critical Reviews in Biochemistry and Molecular Biology. 47, 3, p. 207-21 15 p.

      Research output: Contribution to journal › Review › Research › peer-review

    2. Published

      A novel TPR-BEN domain interaction mediates PICH-BEND3 association

      Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

      Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Mechanics of CRISPR-Cas12a and engineered variants on λ-DNA

      Paul, B., Chaubet, L., Verver, D. E. & Montoya, Guillermo, 2022, In: Nucleic Acids Symposium Series. 50, 9, p. 5208-5225 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      CRISPR-Cas12a: functional overview and applications

      Paul, B. & Montoya, Guillermo, 2020, In: Biomedical Journal. 43, 1, p. 8-17

      Research output: Contribution to journal › Review › Research › peer-review

    6. Published

      Crystal structure of the open conformation of the mammalian chaperonin CCT in complex with tubulin

      Muñoz, I. G., Yébenes, H., Zhou, M., Mesa, Pablo, Serna, M., Park, A. Y., Bragado-Nilsson, E., Beloso, A., de Cárcer, G., Malumbres, M., Robinson, C. V., Valpuesta, J. M. & Montoya, Guillermo, Jan 2011, In: Nature Structural & Molecular Biology. 18, 1, p. 14-9 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Molecular basis of Tousled-Like Kinase 2 activation

      Mortuza, G. B., Hermida, D., Pedersen, A., Segura-Bayona, S., López-Méndez, B., Redondo, P., Rüther, P., Pozdnyakova, I., Garrote, A. M., Muñoz, I. G., Villamor-Payà, M., Jauset, C., Olsen, Jesper Velgaard, Stracker, T. H. & Montoya, Guillermo, 2018, In: Nature Communications. 9, 1, p. 2535 2535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      XTACC3-XMAP215 association reveals an asymmetric interaction promoting microtubule elongation

      Mortuza, G. B., Cavazza, T., Garcia-Mayoral, M. F., Hermida, D., Peset, I., Pedrero, J. G., Merino, N., Blanco, F. J., Lyngsø, J., Bruix, M., Pedersen, J. S., Vernos, I. & Montoya, Guillermo, 29 Sep 2014, In: Nature Communications. 5, p. 1-12 12 p., 5072.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Editorial overview: Protein-nucleic acid interactions: 'Takes two to Tango'

      Montoya, Guillermo & Carlomagno, T., 2020, In: Current Opinion in Structural Biology. 65, p. v-vi 2 p.

      Research output: Contribution to journal › Editorial › Research

    10. Published

      How do CRISPR-Cas RNA-guided endonucleases cut specific DNA regions for Genome Editing?

      Montoya, Guillermo, 2018, In: Acta Crystallographica Section A: Foundations and Advances. 74, p. E3 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research

    11. Published

      Structural basis of cyclic oligoadenylate degradation by ancillary Type III CRISPR-Cas ring nucleases

      Molina Monterrubio, R. A., Jensen, A. L. G., Marchena-Hurtado, J., López-Méndez, B., Stella, S. & Montoya, Guillermo, 2021, In: Nucleic Acids Research. 49, 21, p. 12577-12590 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Structure of Csx1-cOA4 complex reveals the basis of RNA decay in Type III-B CRISPR-Cas

      Molina, R., Stella, S., Feng, M., Sofos, N., Jauniskis, V., Pozdnyakova, I., López-Méndez, B., She, Q. & Montoya, Guillermo, 2019, In: Nature Communications. 10, 14 p., 4302.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Visualizing phosphodiester-bond hydrolysis by an endonuclease

      Molina, R., Stella, S., Redondo, P., Gomez, H., Marcaida, M. J., Orozco, M., Prieto, J. & Montoya, Guillermo, Jan 2015, In: Nature Structural and Molecular Biology. 22, 1, p. 65-72 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Non-specific protein-DNA interactions control I-CreI target binding and cleavage

      Molina, R., Redondo, P., Stella, S., Marenchino, M., D'Abramo, M., Gervasio, F. L., Charles Epinat, J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 1 Aug 2012, In: Nucleic Acids Research. 40, 14, p. 6936-6945 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Molecular basis of cyclic tetra-oligoadenylate processing by small standalone CRISPR-Cas ring nucleases

      Molina, R., García Martín, Ricardo, López-Méndez, B., Jensen, A. L. G., Ciges Tomas, Jose Rafael, Marchena-Hurtado, J., Stella, S. & Montoya, Guillermo, 2022, In: Nucleic Acids Research. 50, 19, p. 11199-11213 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Key Players in I-DmoI Endonuclease Catalysis Revealed from Structure and Dynamics

      Molina, R., Besker, N., Marcaida, M. J., Montoya, Guillermo, Prieto, J. & D'Abramo, M., 8 Mar 2016, In: ACS chemical biology. 11, 5, p. 1401–1407

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Engineering a Nickase on the Homing Endonuclease I-DmoI Scaffold

      Molina, R., Marcaida, M. J., Redondo, P., Marenchino, M., Duchateau, P., D'Abramo, M., Montoya, Guillermo & Prieto, J., 2015, In: The Journal of Biological Chemistry. 290, 30, p. 18534-18544 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Crystal Structure of the Homing Endonuclease I-CvuI Provides a New Template for Genome Modification

      Molina, R., Redondo, P., López-Méndez, B., Villate, M., Merino, N., Blanco, F. J., Valton, J., Grizot, S., Duchateau, P., Prieto, J. & Montoya, Guillermo, 27 Nov 2015, In: The Journal of Biological Chemistry. 290, 48, p. 28727-36 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Structural basis of CRISPR-Cas Type III prokaryotic defence systems

      Molina, R., Sofos, N. & Montoya, Guillermo, 2020, In: Current Opinion in Structural Biology. 65, p. 119-129 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    20. Published

      VCF1 is a p97/VCP cofactor promoting recognition of ubiquitylated p97-UFD1-NPL4 substrates

      Mirsanaye, Ann Schirin, Hoffmann, Saskia, Weisser, Melanie, Mund, Andreas, Lopez Mendez, B., Typas, D., van den Boom, J., Benedict, Bente, Hendriks, Ivo Alexander, Nielsen, Michael Lund, Meyer, H., Duxin, Julien, Montoya, Guillermo & Mailand, Niels, 2024, In: Nature Communications. 15, 1, 16 p., 2459.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Directly from the source: endogenous preparations of molecular machines

      Mesa, Pablo, Deniaud, A., Montoya, Guillermo & Schaffitzel, C., Jun 2013, In: Current Opinion in Structural Biology. 23, 3, p. 319-25 7 p.

      Research output: Contribution to journal › Review › Research › peer-review

    22. Published

      Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites

      Lundby, Alicia, Franciosa, Giulia, Emdal, Kristina Bennet, Refsgaard, J. C., Gnosa, S. P., Bekker-Jensen, D. B., Secher, A., Maurya, S. R., Paul, I., Mendez, B. L., Kelstrup, C. D., Francavilla, C., Kveiborg, Marie, Montoya, Guillermo, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2019, In: Cell. 179, 2, p. 543-560

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening

      Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Realizing integration in structural biology: The 2022 ISBUC Annual Meeting

      Kragelund, Birthe Brandt, Loland, Claus Juul, Montoya, Guillermo, Hatzakis, Nikos, Martinez, Karen Laurence, Gajhede, Michael, Christensen, Caspar Elo & Holt, Lucy, 2023, In: Structure. 31, 7, p. 747-754

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Comprehensive analysis of the specificity of transcription activator-like effector nucleases

      Juillerat, A., Dubois, G., Valton, J., Thomas, S., Stella, S., Maréchal, A., Langevin, S., Benomari, N., Bertonati, C., Silva, G. H., Daboussi, F., Epinat, J., Montoya, Guillermo, Duclert, A. & Duchateau, P., Apr 2014, In: Nucleic Acids Research. 42, 8, p. 5390-402 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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