Søren Brunak

Søren Brunak

Professor

ORCID: 0000-0003-0316-5866

Publication year:
All
201 - 300 out of 346Page size: 100
Sort by: Title
  1. Published

    Genetic variability in the absorption of dietary sterols affects the risk of coronary artery disease

    Helgadottir, A., Thorleifsson, G., Alexandersson, K. F., Tragante, V., Thorsteinsdottir, M., Eiriksson, F. F., Gretarsdottir, S., Björnsson, E., Magnusson, O., Sveinbjornsson, G., Jonsdottir, I., Steinthorsdottir, V., Ferkingstad, E., Jensson, B. Ö., Stefansson, H., Olafsson, I., Christensen, A. H., Torp-Pedersen, C., Køber, L., Pedersen, O. B. & 23 others, Erikstrup, C., Sørensen, E., Brunak, Søren, Banasik, Karina, Hansen, Thomas Folkmann, Nyegaard, M., Eyjolfssson, G. I., Sigurdardottir, O., Thorarinsson, B. L., Matthiasson, S. E., Steingrimsdottir, T., Bjornsson, E. S., Danielsen, R., Asselbergs, F. W., Arnar, D. O., Ullum, H., Bundgård, Henning, Sulem, P., Thorsteinsdottir, U., Thorgeirsson, G., Holm, H., Gudbjartsson, D. F. & Stefansson, K., 2020, In: European Heart Journal. 41, 28, p. 2618-2628 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Genetic studies of abdominal MRI data identify genes regulating hepcidin as major determinants of liver iron concentration

    Wilman, H. R., Parisinos, C. A., Atabaki-Pasdar, N., Kelly, M., Thomas, E. L., Neubauer, S., Jennison, C., Ehrhardt, B., Baum, P., Schoelsch, C., Freijer, J., Grempler, R., Graefe-Mody, U., Hennige, A., Dings, C., Lehr, T., Scherer, N., Sihinecich, I., Pattou, F., Raverdi, V. & 31 others, Caiazzo, R., Torres, F., Verkindt, H., Mari, A., Tura, A., Giorgino, T., Bizzotto, Froguel, P., Brorsson, C., Brunak, Søren, De Masi, F., Pedersen, H., Banasik, Karina, Thomas, Cecilia Engel, Lundgaard, Agnete Troen, Nielsen, A., Mazzoni, G., Karaderi, Tugce, Rasmussen, Simon, Johansen, Joachim, Allesøe, R., Arumugam, Mani, Allin, K., Hansen, Torben, Hansen, T., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Dutta, A., Vogt, J., drb459, drb459 & IMI-DIRECT consortium, I. C., 2019, In: Journal of Hepatology. 71, 3, p. 594-602 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Genetic prediction of 33 blood group phenotypes using an existing genotype dataset

    Moslemi, C., Sækmose, S. G., Larsen, R., Bay, J. T., Brodersen, T., Didriksen, M., Hjalgrim, H., Banasik, K., Nielsen, K. R., Bruun, M. T., Dowsett, J., Dinh, K. M., Mikkelsen, S., Mikkelsen, C., Hansen, T. F., Ullum, H., Erikstrup, C., Brunak, S., Krogfelt, K. A., Storry, J. R. & 3 others, Ostrowski, Sisse Rye, Olsson, M. L. & Pedersen, Ole Birger Vesterager, 2023, In: Transfusion. 63, 12, p. 2297-2310 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Genetic insight into sick sinus syndrome

    Thorolfsdottir, R. B., Sveinbjornsson, G., Aegisdottir, H. M., Benonisdottir, S., Stefansdottir, L., Ivarsdottir, E. V., Halldorsson, G. H., Sigurdsson, J. K., Torp-Pedersen, C., Weeke, P. E., Brunak, S., Westergaard, D., Pedersen, O. B., Sørensen, E., Nielsen, K. R., Burgdorf, K. S., Banasik, K., Brumpton, B., Zhou, W., Oddsson, A. & 25 others, Tragante, V., Hjorleifsson, K. E., Davidsson, O. B., Rajamani, S., Jonsson, S., Torfason, B., Valgardsson, A. S., Thorgeirsson, G., Frigge, M. L., Thorleifsson, G., Norddahl, G. L., Helgadottir, A., Gretarsdottir, S., Sulem, P., Jonsdottir, I., Willer, C. J., Hveem, K., Bundgård, Henning, Ullum, H., Arnar, D. O., Thorsteinsdottir, U., Gudbjartsson, D. F., Holm, H., Stefansson, K. & DBDS Genomic Consortium, D. G. C., 2021, In: European Heart Journal. 42, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development

    Hansen, K. L., Greenway, S. C., Rosenfeld, J. A., Wakimoto, H., Gorham, J. M., Segrè, A. V., Roberts, A. E., Smoot, L. B., Pu, W. T., C Pereira, A., Mesquita, S. M., Tommerup, Niels, Brunak, Søren, Ballif, B. C., Shaffer, L. G., Donahoe, P. K., Daly, M. J., Seidman, J. G., Seidman, C. E. & Larsen, Lars Allan, 2012, In: Proceedings of the National Academy of Sciences USA (PNAS). 109, 35, p. 14035-40 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits

    Brown, A. A., Fernandez-Tajes, J. J., Hong, M. G., Brorsson, C. A., Koivula, R. W., Davtian, D., Dupuis, T., Sartori, A., Michalettou, T. D., Forgie, I. M., Adam, J., Allin, K. H., Caiazzo, R., Cederberg, H., De Masi, F., Elders, P. J. M., Giordano, G. N., Haid, M., Hansen, T., Hansen, T. H. & 134 others, Hattersley, A. T., Heggie, A. J., Howald, C., Jones, A. G., Kokkola, T., Laakso, M., Mahajan, A., Mari, A., McDonald, T. J., McEvoy, D., Mourby, M., Musholt, P. B., Nilsson, B., Pattou, F., Penet, D., Raverdy, V., Ridderstråle, M., Romano, L., Rutters, F., Sharma, S., Teare, H., ‘t Hart, L., Tsirigos, Konstantinos, Vangipurapu, J., drb459, drb459, Brunak, Søren, Franks, P. W., Frost, G., Grallert, H., Jablonka, B., McCarthy, M. I., Pavo, I., Pedersen, Oluf Borbye, Ruetten, H., Walker, M., Adragni, K., Allesøe, R. L. L., Artati, A. A., Arumugam, Mani, Atabaki-Pasdar, N., Baltauss, T., Banasik, Karina, Barnett, A. L., Baum, P., Bell, J. D., Beulens, J. W., Bianzano, S. B., Bizzotto, R., Bonnefond, A., Cabrelli, L., Dale, M., Dawed, A. Y., de Preville, N., Dekkers, K. F., Deshmukh, H. A., Dings, C., Donnelly, L., Dutta, A., Ehrhardt, B., pjx571, pjx571, Eriksen, R., Fan, Yong, Ferrer, J., Fitipaldi, H., Forman, A., Fritsche, A., Froguel, P., Gassenhuber, J., Gough, S., Graefe-Mody, U., Grempler, R., Groeneveld, L., Groop, L., Gudmundsdóttir, V., Gupta, R., Hennige, A. M. H., Hill, A. V., Holl, R. W., Hudson, M., Jacobsen, Ulrik Plesner, Jennison, C., Johansen, Joachim, Jonsson, Anna Elisabet, Karaderi, Tugce, Kaye, J., Kennedy, G., Klintenberg, M., Kuulasmaa, T., Lehr, T., Loftus, H., Lundgaard, Agnete Troen, Mazzoni, G., McRobert, N., McVittie, I., Nice, R., Nicolay, C., Nijpels, G., Palmer, C. N., Pedersen, H. K., Perry, M. H., Pomares-Millan, H., Prehn, C. P., Ramisch, A., Rasmussen, Simon, Robertson, N., Rodriquez, M., Sackett, P., Scherer, N., Shah, N., Sihinevich, I., Slieker, R. C., Sondertoft, N. B., Steckel-Hamann, B., Thomas, M. K., Thomas, Cecilia Engel, Thomas, E. L. L., Thorand, B., Thorne, C. E., Tillner, J., Tura, A., Uhlen, M., van Leeuwen, N., van Oort, S., Verkindt, H., Vogt, J., Wad Sackett, P. W., Wesolowska-Andersen, A., Whitcher, B., White, M. W., Adamski, J., Schwenk, J. M., Pearson, E. R., Dermitzakis, E. T. & Viñuela, A., 2023, In: Nature Communications. 14, 17 p., 5062.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Genetic Variants Close to TTN, NKX2-5, and MYH6 Associate With AVNRT

    Andreasen, L., Ahlberg, G., Ægisdóttir, H. M., Sveinbjörnsson, G., Lundegaard, P. R., Hartmann, J. P., Paludan-Müller, C., Hadji-Turdeghal, K., Ghouse, J., Pehrson, S., Jensen, H. K., Riahi, S., Hansen, J., Sandgaard, N., Sørensen, E., Banasik, K., Sækmose, S. G., Bruun, M. T., Hjalgrim, H., Erikstrup, C. & 18 others, Pedersen, Ole Birger Vesterager, Wittig, M., Haunsø, Stig, Ostrowski, Sisse Rye, Genomic Consortium, D., Franke, A., Brunak, Søren, Kanters, Jørgen K., Ellervik, Christina, Bundgård, Henning, Ullum, H., Gudbjartsson, D. F., Thorsteinsdottir, U., Holm, H., Arnar, D. O., Stefansson, K., Svendsen, Jesper Hastrup & Olesen, Morten Steen Salling, 2022, In: Circulation Research. 131, 10, p. 862-865

    Research output: Contribution to journal › Letter › Research › peer-review

  8. Published

    Gene expression signature predicts rate of type 1 diabetes progression

    Suomi, T., Starskaia, I., Kalim, U. U., Rasool, O., Jaakkola, M. K., Grönroos, T., Välikangas, T., Brorsson, C., Mazzoni, G., Bruggraber, S., Overbergh, L., Dunger, D., Peakman, M., Chmura, P., Brunak, S., Schulte, A. M., Mathieu, C., Knip, M., Lahesmaa, R., Elo, L. L. & 4 others, Pociot, Flemming, Johannesen, Jesper, Rossing, Peter & INNODIA consortium, I. C., 2023, In: EBioMedicine. 92, 18 p., 104625.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis

    Estonian Biobank, E. B. & DBDS Genomic Consortium, D. G. C., 2024, In: Communications Biology . 7, 1, 10 p., 504.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Functionality of system components: conservation of protein function in protein feature space

    Jensen, L. J., Ussery, D. & Brunak, Søren, 2003, In: Genome Research. 13, 11, p. 2444-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

    Wesolowska-Andersen, A., Brorsson, C. A., Bizzotto, R., Mari, A., Tura, A., Koivula, R., Mahajan, A., Vinuela, A., Tajes, J. F., Sharma, S., Haid, M., Prehn, C., Artati, A., Hong, M. G., Musholt, P. B., Kurbasic, A., Masi, F. D., Tsirigos, K., Pedersen, H. K., Gudmundsdottir, V. & 31 others, Thomas, Cecilia Engel, Banasik, Karina, Jennison, C., Jones, A., Kennedy, G., Bell, J., Thomas, L., Frost, G., Thomsen, H., Allin, K., Hansen, T. H., drb459, drb459, Hansen, Torben, Rutters, F., Elders, P., t'Hart, L., Bonnefond, A., Canouil, M., Brage, S., Kokkola, T., Heggie, A., McEvoy, D., Hattersley, A., McDonald, T., Teare, H., Ridderstrale, M., Walker, M., Forgie, I., Pedersen, Oluf Borbye, Brunak, Søren & IMI-DIRECT consortium, I. C., 2022, In: Cell Reports Medicine. 3, 1, 25 p., 100477.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Finding Ophthalmic Risk and Evaluating the Value of Eye exams and their predictive Reliability (FOREVER)—A cohort study in a Danish high street optician setting: Design and methodology

    Freiberg, J., Rovelt, J., Gazzard, G., Cour, M. L., Kolko, M., Torp‐Pedersen, C., Benn, M., Brunak, S., Cour, M. L., Tolstrup, J., Toft‐Petersen, A. P., Burgdorf, K. S., Banasik, K., Chmura, P. J., Freiberg, J., Rovelt, J., Thornit, D. N., Foster, P., Gazzard, G., Crabb, D. P. & 4 others, Viswanathan, A., Barman, Sarah, Owen, C. G. & Rudnicka, A. R., 2024, In: Acta Ophthalmologica. 102, 1, p. 80-90 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Familial co-occurrence of congenital heart defects follows distinct patterns

    Ellesøe, S. G., Workman, C. T., Bouvagnet, P., Loffredo, C. A., McBride, K. L., Hinton, R. B., van Engelen, K., Gertsen, E. C., Mulder, B. J. M., Postma, A. V., Anderson, R. H., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, Mar 2018, In: European Heart Journal. 39, 12, p. 1015–1022

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Familial Atrial Septal Defect and Sudden Cardiac Death: Identification of a Novel NKX2-5 Mutation and a Review of the Literature

    Ellesøe, S. G., Johansen, M. M., Bjerre, J. V., Hjortdal, V. E., Brunak, Søren & Larsen, Lars Allan, 1 May 2016, In: Congenital Heart Disease. 11, 3, p. 283–290 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Facilitating the use of large-scale biological data and tools in the era of translational bioinformatics

    Kouskoumvekaki, I., Shublaq, N. & Brunak, Søren, 1 Aug 2013, In: Briefings in Bioinformatics. 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Extrapolation of drug induced liver injury responses from cancer cell lines using machine learning approaches

    Aguayo-Orozco, A., Brunak, Søren & Taboureau, O., 2021, In: Computational Toxicology. 17, 6 p., 100147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Expression profiling of human genetic and protein interaction networks in type 1 diabetes

    Brorsson, C., Lage, K., Nielsen, J. H., Brunak, Søren & Pociot, F., 2009, In: PLoS ONE. 4, 7, p. e6250

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Evolution of cell cycle control: same molecular machines, different regulation

    de Lichtenberg, U., Jensen, T. S., Brunak, Søren, Bork, P. & Jensen, L. J., 2007, In: Cell Cycle. 6, 15, p. 1819-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Estimating the effect of donor sex on red blood cell transfused patient mortality: A retrospective cohort study using a targeted learning and emulated trials-based approach

    Bruun-Rasmussen, P., Andersen, Per Kragh, Banasik, Karina, Brunak, Søren & Jo­hans­son, Pär In­ge­mar , 2022, In: EClinicalMedicine. 51, 10 p., 101628.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Estimating heritability and genetic correlations from large health datasets in the absence of genetic data

    Jia, G., Li, Y., Zhang, H., Chattopadhyay, I., Jensen, A. B., Blair, D. R., Davis, L., Robinson, P. N., Dahlen, T., Brunak, Søren, Benson, M., Edgren, G., Cox, N. J., Gao, X. & Rzhetsky, A., 2019, In: Nature Communications. 10, 11 p., 5508.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Established risk loci for systemic lupus erythematosus at NCF2, STAT4, TNPO3, IRF5 and ITGAM associate with distinct clinical manifestations: A Danish genome-wide association study

    DBDS Genomic Consortium, D. G. C., 2022, In: Joint Bone Spine. 89, 4, 105357.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  22. Published

    Erratum to: Dose-Specific Adverse Drug Reaction Identification in Electronic Patient Records: Temporal Data Mining in an Inpatient Psychiatric Population

    Eriksson, R., Werge, T., Jensen, Lars Juhl & Brunak, Søren, May 2014, In: Drug Safety. 37, 5, p. 379

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women

    Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Eliciting drug safety signals from patient records: a language-agnostic approach

    Kaas-Hansen, Benjamin Skov, Placido, Davide, Rodriguez, C., Thorsen-Meyer, H., Gentile, S., Nielsen, A., Brunak, Søren, Jürgens, Gesche & Andersen, S., 2022, p. S15-S16. 2 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  26. Published

    Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor

    Dowsett, J., Ferkingstad, E., Rasmussen, L. J. H., Thørner, L. W., Magnússon, M. K., Sugden, K., Thorleifsson, G., Frigge, M., Burgdorf, K. S., Ostrowski, S. R., Sørensen, E., Erikstrup, C., Pedersen, O. B., Hansen, T. F., Banasik, K., Brunak, S., Tragante, V., Lund, S. H., Stefansdottir, L., Gunnarson, B. & 10 others, Poulton, R., Arseneault, L., Caspi, A., Moffitt, T. E., Gudbjartsson, D., Eugen-Olsen, J., Stefánsson, H., Stefánsson, K., Ullum, H. & DBDS Genomic Consortium, D. G. C., 2021, In: Communications Biology . 4, 1, p. 655

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effects of active farnesoid X receptor on GLUTag enteroendocrine L cells

    Niss, K., Jakobsson, M. E., Westergaard, David, Belling, K. G., Olsen, Jesper Velgaard & Brunak, Søren, 2020, In: Molecular and Cellular Endocrinology. 517, 9 p., 110923.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Early divergent strains of Yersinia pestis in Eurasia 5,000 years ago

    Rasmussen, S., Allentoft, M. E., Nielsen, K., Orlando, L. A. A., Sikora, M., Sjögren, K-G., Pedersen, A. G., Schubert, M., Van Dam, A., Kapel, C. M. O., Nielsen, H. B., Brunak, S., Avetisyan, P., Epimakhov, A., Khalyapin, M. V., Gnuni, A., Kriiska, A., Lasak, I., Metspalu, M., Moiseyev, V. & 11 others, Gromov, A., Pokutta, D., Saag, L., Varul, L., Yepiskoposyan, L., Sicheritz-Ponten, T., Foley, R. A., Lahr, M. M., Nielsen, R., Kristiansen, K. & Willerslev, Eske, 2015, In: Cell. 163, 3, p. 571-582 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Early differences in islets from prediabetic NOD mice: combined microarray and proteomic analysis

    Crèvecoeur, I., Gudmundsdottir, V., Vig, S., Marques Câmara Sodré, F., D'Hertog, W., Fierro, A. C., Van Lommel, L., Gysemans, C., Marchal, K., Waelkens, E., Schuit, F., Brunak, Søren, Overbergh, L. & Mathieu, C., Mar 2017, In: Diabetologia. 60, 3, p. 475-489 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    ELIXIR-EXCELERATE: establishing Europe's data infrastructure for the life science research of the future

    ELIXIR-EXCELERATE Community, E. C., 2021, In: EMBO Journal. 40, 6, 9 p., e107409.

    Research output: Contribution to journal › Comment/debate › Research

  31. Dynamic complex formation during the yeast cell cycle

    de Lichtenberg, U., Jensen, L. J., Brunak, Søren & Bork, P., 2005, In: Science (New York, N.Y.). 307, 5710, p. 724-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Dynamic and explainable machine learning prediction of mortality in patients in the intensive care unit: a retrospective study of high-frequency data in electronic patient records

    Thorsen-Meyer, H., Nielsen, A. B., Nielsen, A. P., Kaas-Hansen, Benjamin Skov, Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Dybdahl, L., Spangsege, L., Hulsen, P., Belling, K., Brunak, Søren & Perner, Anders, 2020, In: The Lancet Digital Health. 2, 4, p. e179–91 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Drug interactions in hospital prescriptions in Denmark: Prevalence and associations with adverse outcomes

    Rodríguez, C. L., Kaas-Hansen, Benjamin Skov, Eriksson, R., Biel, J. H., Belling, K. G., Andersen, Stig Ejdrup & Brunak, Søren, 2022, In: Pharmacoepidemiology and Drug Safety. 31, 6, p. 632-642 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Drug dosage modifications in 24 million in-patient prescriptions covering eight years: A Danish population-wide study of polypharmacy

    Leal Rodríguez, C., Haue, Amalie Dahl, Mazzoni, G., Eriksson, R., Hernansanz Biel, J., Cantwell, Lisa, Westergaard, David, Belling, K. G. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 9, 27 p., e0000336.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Dose-specific adverse drug reaction identification in electronic patient records: temporal data mining in an inpatient psychiatric population

    Eriksson, R., Werge, T., Jensen, Lars Juhl & Brunak, Søren, Apr 2014, In: Drug Safety. 37, 4, p. 237-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Dissecting spatio-temporal protein networks driving human heart development and related disorders

    Hansen, K. L., Møllgård, K., Greenway, S., Wakimoto, H., Gorham, J. M., Workman, C. T., Bendsen, E., Hansen, N. T., Rigina, O., Roque, F. S., Wiese, C., Christoffels, V. M., Roberts, A. E., Smoot, L. B., Pu, W. T., Donahoe, P. K., Tommerup, N., Brunak, S., Seidman, C. E., Seidman, J. G. & 1 others, Larsen, Lars Allan, 2010, In: Molecular Systems Biology. 6, p. 381

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Yvonne Voigt, A., Vestergaard, H., Hercog, R., Igor Costea, P., Roat Kultima, J., Li, J., Jørgensen, T., Levenez, F. & 9 others, Dore, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Dusko Ehrlich, S., Bork, P. & Pedersen, Oluf Borbye, 2015, In: Nature. 528, 7581, p. 262-266 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients

    Siggaard, T., Reguant, R., Jørgensen, Isabella Friis, Haue, Amalie Dahl, Lademann, M., Aguayo-Orozco, A., Hjaltelin, Jessica Xin, Jensen, A. B., Banasik, Karina & Brunak, Søren, 2020, In: Nature Communications. 11, 1, 10 p., 4952.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Disease Trajectories for Hidradenitis Suppurativa in the Danish Population

    Andersen, Rune Kjærsgaard, Jørgensen, Isabella Friis, Reguant, R., Jemec, Gregor & Brunak, Søren, 2020, In: JAMA Dermatology. 156, 7, p. 780-786

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Discrete-time survival analysis in the critically ill: a deep learning approach using heterogeneous data

    Thorsen-Meyer, H., Placido, Davide, Kaas-Hansen, Benjamin Skov, Nielsen, A. P., Lange, Theis, Nielsen, A. B., Toft, P., Schierbeck, J., Strøm, T., Chmura, Piotr Jaroslaw, Heimann, M., Belling, K., Perner, Anders & Brunak, Søren, 2022, In: npj Digital Medicine. 5, 10 p., 142.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Discrepancies in listed adverse drug reactions in pharmaceutical product information supplied by the regulatory authorities in Denmark and the USA

    Eriksson, R., Aagaard, L., Jensen, Lars Juhl, Borisova, L., Hørlück, D., Brunak, Søren & Hansen, E. H., 2014, In: Pharmacology Research & Perspectives. 2, 3, p. 1-10 e00038.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models: [with Author Correction]

    Allesøe, R. L., Lundgaard, A. T., Hernández Medina, R., Aguayo-Orozco, A., Johansen, J., Nissen, J. N., Brorsson, C., Mazzoni, G., Niu, L., Biel, J. H., Brasas, V., Webel, H., Benros, M. E., Pedersen, A. G., Chmura, P. J., Jacobsen, U. P., Mari, A., Koivula, R., Mahajan, A., Vinuela, A. & 31 others, Tajes, J. F., Sharma, S., Haid, M., Hong, M., Musholt, P. B., De Masi, F., Vogt, J., Pedersen, H. K., Gudmundsdottir, V., Jones, A., Kennedy, G., Bell, J., Thomas, E. L., Frost, G., Thomsen, Henrik S., Hansen, E., Hansen, T. H., drb459, drb459, Muilwijk, M., Blom, M. T., 't Hart, L. M., Pattou, F., Raverdy, V., Brage, S., Ridderstråle, M., Pedersen, Oluf Borbye, Hansen, Torben, Banasik, Karina, Rasmussen, Simon, Brunak, Søren & IMI-DIRECT consortium, I. C., 2023, In: Nature Biotechnology. 41, 3, p. 399–408 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: rationale and design of the epidemiological studies within the IMI DIRECT Consortium: Diabetologia

    Koivula, R., Heggie, A., Barnett, A., Cederberg, H., Hansen, T. H., Koopman, A., Ridderstråle, M., Rutters, F., Vestergaard, H., Gupta, R., Herrgård, S., Heymans, M., Perry, M., Rauh, S., Siloaho, M., Teare, H. A., Thorand, B., Bell, J., Brunak, S., Frost, G. & 13 others, Jablonka, B., Mari, A., McDonald, T., Dekker, J., Hansen, Torben, Hattersley, A., Laakso, M., Pedersen, Oluf Borbye, Koivisto, V., Ruetten, H., Walker, M., Pearson, E. & Franks, P., 2014, In: Diabetologia. 57, 6, p. 1-11 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: descriptive characteristics of the epidemiological studies within the IMI DIRECT Consortium

    Koivula, R. W., Forgie, I. M., Kurbasic, A., Viñuela, A., Heggie, A., Giordano, G. N., Hansen, T. H., Hudson, M., Koopman, A. D. M., Rutters, F., Siloaho, M., Allin, K. H., Brage, S., Brorsson, C. A., Dawed, A. Y., De Masi, F., Groves, C. J., Kokkola, T., Mahajan, A., Perry, M. H. & 31 others, Rauh, S. P., Ridderstråle, M., Teare, H. J. A., Thomas, E. L., Tura, A., drb459, drb459, White, T., Adamski, J., Bell, J. D., Beulens, J. W., Brunak, Søren, Dermitzakis, E. T., Froguel, P., Frost, G., Gupta, R., Hansen, Torben, Hattersley, A., Jablonka, B., Kaye, J., Laakso, M., McDonald, T. J., Pedersen, Oluf Borbye, Schwenk, J. M., Pavo, I., Mari, A., McCarthy, M. I., Ruetten, H., Walker, M., Pearson, E., Franks, P. W. & IMI-DIRECT consortium, I. C., 2019, In: Diabetologia. 62, 9, p. 1601-1615

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Dietary metabolite profiling brings new insight into the relationship between nutrition and metabolic risk: An IMI DIRECT study

    Eriksen, R., Perez, I. G., Posma, J. M., Haid, M., Sharma, S., Prehn, C., Thomas, L. E., Koivula, R. W., Bizzotto, R., Prehn, C., Mari, A., Giordano, G. N., Pavo, I., Schwenk, J. M., De Masi, F., Tsirigos, K. D., Brunak, S., Viñuela, A., Mahajan, A., McDonald, T. J. & 18 others, Kokkola, T., Rutter, F., Teare, H., Hansen, T. H., Fernandez, J., Jones, A., Jennison, C., Walker, M., McCarthy, M. I., Pedersen, Oluf Borbye, Ruetten, H., Forgie, I., Bell, J. D., Pearson, E. R., Franks, P. W., Adamski, J., Holmes, E. & Frost, G., Aug 2020, In: EBioMedicine. 58, p. 102932

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Dictionary construction and identification of possible adverse drug events in Danish clinical narrative text

    Eriksson, R., Jensen, P. B., Pletscher-Frankild, S., Jensen, Lars Juhl & Brunak, Søren, 23 May 2013, In: JAMIA - Journal of the American Medical Informatics Association. 20, 5, p. 947-953 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Diagnosis trajectories of prior multi-morbidity predict sepsis mortality

    Beck, M. K., Jensen, A. B., Nielsen, A. B., Perner, Anders, Moseley, P. L. & Brunak, Søren, 4 Nov 2016, In: Scientific Reports. 6, 9 p., 36624.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Development of a dynamic prediction model for unplanned ICU admission and mortality in hospitalized patients

    Placido, Davide, Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Reguant, R. & Brunak, Søren, 2023, In: PLOS Digital Health. 2, 6, 18 p., e0000116.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Development and validation of a dynamic prediction model for unplanned ICU admission and mortality in hospitalized patients

    Placido, Davide, Thorsen-Meyer, H., Kaas-Hansen, Benjamin Skov, Reguant, R. & Brunak, Søren, 2022.

    Research output: Working paper › Preprint › Research

  50. E-pub ahead of print

    Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study

    Winther-Sørensen, Marie, Garcia, S. L., Bartholdy, Andreas, Ottenheijm, Maud Eline, Banasik, Karina, Brunak, Søren, Sorensen, Charlotte Mehlin, Gluud, Lise Lotte, Knop, Filip Krag, Holst, Jens Juul, Rosenkilde, Mette, Jensen, Majken Karoline & Albrechtsen, Nicolai Jacob Wewer, 6 May 2024, (E-pub ahead of print) In: Diabetologia.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Detection of Molecular Signatures of Homologous Recombination Deficiency in Bladder Cancer

    Pilmark, Judit Börcsök, Diossy, M., Sztupinszki, Z., Prosz, A., Tisza, V., Spisak, S., Rusz, O., Stormoen, D. R., Pappot, Helle, Csabai, I., Brunak, Søren, Mouw, K. W. & Szallasi, Z., 2021, In: Clinical Cancer Research. 27, 13, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Detailed stratified GWAS analysis for severe COVID-19 in four European populations

    Degenhardt, F., Ellinghaus, D., Juzenas, S., Lerga-Jaso, J., Wendorff, M., Maya-Miles, D., Uellendahl-Werth, F., ElAbd, H., Rühlemann, M. C., Arora, J., Özer, O., Lenning, O. B., Myhre, R., Vadla, M. S., Wacker, E. M., Wienbrandt, L., Ortiz, A. B., Salazar, A., Chercoles, A. G., Palom, A. & 31 others, Ruiz, A., Garcia-Fernandez, A., Blanco-Grau, A., Mantovani, A., Zanella, A., Holten, A. R., Mayer, A., Bandera, A., Cherubini, A., Protti, A., Aghemo, A., Gerussi, A., Ramirez, A., Braun, A., Nebel, A., Barreira, A., Lleo, A., Teles, A., Kildal, A. B., Biondi, A., Caballero-Garralda, A., Ganna, A., Gori, A., Glück, A., Lind, A., Hinney, A., Jensen, B., Banasik, Karina, Castro, P., Brunak, Søren & COVICAT study group, Aachen Study (COVAS), C. S. G. A. S. (., 2022, In: Human Molecular Genetics. 31, 23, p. 3945-3966 22 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Deficit of homozygosity among 1.52 million individuals and genetic causes of recessive lethality

    Oddsson, A., Sulem, P., Sveinbjornsson, G., Arnadottir, G. A., Steinthorsdottir, V., Halldorsson, G. H., Atlason, B. A., Oskarsson, G. R., Helgason, H., Nielsen, H. S., Westergaard, D., Karjalainen, J. M., Katrinardottir, H., Fridriksdottir, R., Jensson, B. O., Tragante, V., Ferkingstad, E., Jonsson, H., Gudjonsson, S. A., Beyter, D. & 31 others, Moore, K. H. S., Thordardottir, H. B., Kristmundsdottir, S., Stefansson, O. A., Rantapää-Dahlqvist, S., Sonderby, I. E., Didriksen, Maria, Stridh, P., Haavik, J., Tryggvadottir, L., Frei, O., Walters, G. B., Kockum, I., Hjalgrim, Henrik, Olafsdottir, T. A., Selbaek, G., Nyegaard, M., Erikstrup, C., Brodersen, T., Saevarsdottir, S., Olsson, T., Nielsen, K. R., Hansen, Thomas Folkmann, Brunak, Søren, Jacobsen, R. L., Brunak, Søren, Banasik, Karina, Askling, J., Pedersen, Ole Birger Vesterager, Ostrowski, Sisse Rye & DBDS Genomic Consortium, D. G. C., 2023, In: Nature Communications. 14, 15 p., 3453.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Deep integrative models for large-scale human genomics

    Sigurdsson, Arnór Ingi, Louloudis, Ioannis, Banasik, Karina, Westergaard, David, Winther, Ole, Lund, O., Ostrowski, Sisse Rye, Erikstrup, C., Pedersen, Ole Birger Vesterager, Nyegaard, Mette, Brunak, Søren, Vilhjálmsson, B. & Rasmussen, Simon, 2023, In: Nucleic Acids Symposium Series. 51, 12, 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Data Resource Profile: The Copenhagen Hospital Biobank (CHB)

    Sørensen, E., Christiansen, L., Wilkowski, B., Larsen, M. H., Burgdorf, Kristoffer Sølvsten, Thørner, L. W., Nissen, J., Pedersen, Ole Birger Vesterager, Banasik, Karina, Brunak, Søren, Bundgård, Henning, Stefánsson, H., Stefánsson, K., Melbye, M. & Ullum, H., 2021, In: International Journal of Epidemiology. 50, 3, p. 719-720e

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    DanMAC5: a browser of aggregated sequence variants from 8,671 whole genome sequenced Danish individuals

    Banasik, K., Møller, P. L., Techlo, T. R., Holm, P. C., Walters, G. B., Ingason, A., Rosengren, A., Rohde, P. D., Kogelman, L. J. A., Westergaard, D., Siggaard, T., Chmura, P. J., Chalmer, M. A., Magnússon, Ó., Þórisson, G., Stefánsson, H., Guðbjartsson, D. F., Stefánsson, K., Olesen, J., Winther, S. & 5 others, Bøttcher, M., Brunak, Søren, Werge, Thomas, Nyegaard, M. & Hansen, Thomas Folkmann, 2023, In: BMC Genomic Data. 24, 1, 4 p., 30.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  57. Published

    DBDS Genomic Cohort, a prospective and comprehensive resource for integrative and temporal analysis of genetic, environmental and lifestyle factors affecting health of blood donors

    Hansen, T. F., Banasik, K., Erikstrup, C., Pedersen, O. B., Westergaard, D., Chmura, P. J., Nielsen, K., Thørner, L., Hjalgrim, H., Paarup, H., Larsen, M. A. H., Petersen, M., Jennum, P., Andersen, S., Nyegaard, M., Jemec, G. B. E., Olesen, J., Werge, T., Johansson, P. I., Sørensen, E. & 3 others, Brunak, Søren, Ullum, H. & Burgdorf, Kristoffer Sølvsten, 9 Jun 2019, In: BMJ Open. 9, 6, p. 1-7 7 p., e028401.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Cyclebase.org: version 2.0, an updated comprehensive, multi-species repository of cell cycle experiments and derived analysis results

    Gauthier, N. P., Jensen, Lars Juhl, Wernersson, R., Brunak, Søren & Jensen, T. S., 2010, In: Nucleic Acids Research. 38, Database issue, p. D699-702

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Cutavirus in cutaneous malignant melanoma

    Mollerup, S., Fridholm, E. M. H., Vinner, Lasse, Kjartansdóttir, K. R., Friis-Nielsen, J., Asplund, M., Romero, J. A. H., Steiniche, T., Mourier, T., Brunak, Søren, Willerslev, Eske, Izarzugaza, J. M. G., Hansen, Anders Johannes & Nielsen, L. P., Feb 2017, In: Emerging Infectious Diseases . 23, 2, p. 363-365 3 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  60. Published

    Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel disease

    Uellendahl-Werth, F., Maj, C., Borisov, O., Juzenas, S., Wacker, E. M., Jorgensen, I. F., Steiert, T. A., Bej, S., Krawitz, P., Hoffmann, P., Schramm, C., Wolkenhauer, O., Banasik, K., Brunak, S., Schreiber, S., Karlsen, T. H., Degenhardt, F., Noethen, M., Franke, A., Folseraas, T. & 1 others, Ellinghaus, D., 2022, In: Communications Biology. 5, 15 p., 80.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Country-specific chemical signatures of persistent environmental compounds in breast milk

    Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T., Kiviranta, H., Taboureau, O., Brunak, S., Main, K. M., Krysiak-Baltyn, K., Toppari, J., Skakkebaek, N. E., Jensen, T. S., Virtanen, H. E., Schramm, K-W., Shen, H., Vartiainen, T. & 4 others, Kiviranta, H., Taboureau, O., Brunak, S. & Main, Katharina Maria, 1 Apr 2010, In: International Journal of Andrology. 33, 2, p. 270-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Cost-effective multiplexing before capture allows screening of 25 000 clinically relevant SNPs in childhood acute lymphoblastic leukemia

    Wesolowska, A., Gautier, L., Weinhold, N., Audouze, K. M. L., Brunak, Søren, Sicheritz-Ponten, T., Gupta, R., Dalgaard, M. D., Nielsen, B. F., Leffers, H., Borst, L., Helt, L. R., Nersting, J., Schmiegelow, Kjeld, Bak, M. & Tommerup, Niels, 1 Jun 2011, In: Leukemia. 25, 6, p. 1001-1006 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Corrigendum: Disentangling type 2 diabetes and metformin treatment signatures in the human gut microbiota

    Forslund, K., Hildebrand, F., Nielsen, T., Falony, G., Le Chatelier, E., Sunagawa, S., Prifti, E., Vieira-Silva, S., Gudmundsdottir, V., Pedersen, H. K., Arumugam, M., Kristiansen, K., Voigt, A. Y., Vestergaard, H., Hercog, R., Costea, P. I., Kultima, J. R., Li, J., Jørgensen, T., Levenez, F. & 10 others, Doré, J., Nielsen, H. B., Brunak, Søren, Raes, J., Hansen, Torben, Wang, J., Ehrlich, S. D., Bork, P., Pedersen, Oluf Borbye & MetaHIT consortium, M. C., 3 May 2017, In: Nature. 545, 116, 1 p., 22318.

    Research output: Contribution to journal › Comment/debate › Research

  64. Published

    Contaminating viral sequences in high-throughput sequencing viromics: a linkage study of 700 sequencing libraries

    Asplund, M., Kjartansdóttir, K. R., Mollerup, S., Vinner, L., Fridholm, H., Herrera, J. A. R., Friis-Nielsen, J., Hansen, T. A., Jensen, R. H., Nielsen, I. B., Richter, S. R., Rey-Iglesia, A., Matey-Hernandez, M. L., Alquezar-Planas, D. E., Olsen, P. V. S., Sicheritz-Pontén, T., Willerslev, E., Lund, O., Brunak, S., Mourier, T. & 3 others, Nielsen, L. P., Izarzugaza, J. M. G. & Hansen, Anders Johannes, 2019, In: Clinical Microbiology and Infection. 25, 10, p. 1277-1285

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Consistent metagenes from cancer expression profiles yield agent specific predictors of chemotherapy response

    Li, Q., Eklund, A. C., Birkbak, N. J., Desmedt, C., Haibe-Kains, B., Sotiriou, C., Symmans, W. F., Pusztai, L., Brunak, Søren, Richardson, A. L. & Szallasi, Z. I., 2011, In: B M C Bioinformatics. 12, p. 310

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Conflicting associations between dietary patterns and changes of anthropometric traits across subgroups of middle-aged women and men

    Jiang, L., Audouze, K., Romero Herrera, J. A., Ängquist, Lars, Kjærulff, S. K., Izarzugaza, J. M. G., Tjønneland, Anne, Halkjær, J., Overvad, K., Sørensen, Thorkild I.A. & Brunak, Søren, 2020, In: Clinical Nutrition. 39, 1, p. 265-275

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Concordance of gene expression in human protein complexes reveals tissue specificity and pathology

    Börnigen, D., Pers, T. H., Thorrez, L., Huttenhower, C., Moreau, Y. & Brunak, Søren, 5 Aug 2013, In: Nucleic Acids Research. 41, 18, p. e171

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Complex effects of sequence variants on lipid levels and coronary artery disease

    Snaebjarnarson, A. S., Helgadottir, A., Arnadottir, G. A., Ivarsdottir, E. V., Thorleifsson, G., Ferkingstad, E., Einarsson, G., Sveinbjornsson, G., Thorgeirsson, T. E., Ulfarsson, M. O., Halldorsson, B. V., Olafsson, I., Erikstrup, C., Pedersen, O. B., Nyegaard, M., Bruun, M. T., Ullum, H., Brunak, S., Iversen, K. K., Christensen, A. H. & 14 others, Olesen, Morten Steen Salling, Ghouse, Jonas, Banasik, Karina, Knowlton, K. U., Arnar, D. O., Thorgeirsson, G., Nadauld, L., Ostrowski, Sisse Rye, Bundgård, Henning, Holm, H., Sulem, P., Stefansson, K., Gudbjartsson, D. F. & DBDS Genomic Consortium, D. G. C., 2023, In: Cell. 186, 19, p. 4085-4099.e15

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Complete genes may pass from food to human blood

    Spisák, S., Solymosi, N., Ittzés, P., Bodor, A., Kondor, D., Vattay, G., Barták, B. K., Sipos, F., Galamb, O., Tulassay, Z., Szállási, Z., Rasmussen, Simon, Sicheritz-Ponten, T., Brunak, Søren, Molnár, B. & Csabai, I., 2013, In: PloS one. 8, 7, p. e69805

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Complete Topological Mapping of a Cellular Protein Interactome Reveals Bow-Tie Motifs as Ubiquitous Connectors of Protein Complexes

    Niss, K., Gomez-Casado, C., Hjaltelin, Jessica Xin, Joeris, T., Agace, W. W., Belling, K. G. & Brunak, Søren, 2020, In: Cell Reports. 31, 11, 15 p., 107763.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Compass: A hybrid method for clinical and biobank data mining

    Krysiak-Baltyn, K., Nordahl Petersen, T., Audouze, K. M. L., Jørgensen, N., Ängquist, Lars & Brunak, Søren, Feb 2014, In: Journal of Biomedical Informatics. 47, p. 160-170

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

    Gådin, J. R., Buil, A., Colantuoni, C., Jaffe, A. E., Nielsen, J., Shin, J., Hyde, T. M., Kleinman, J. E., Plath, N., Eriksson, P., Brunak, Søren, Didriksen, M., Weinberger, D. R., Folkersen, L. & BrainSeq Consortium, B. C., 2019, In: PLoS ONE. 14, 6, 16 p., e0217765.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Comparison of global gene expression profiles of microdissected human foetal Leydig cells with their normal and hyperplastic adult equivalents

    Lottrup, G., Belling, K., Leffers, H., Nielsen, J. E., Dalgaard, M. D., Juul, Anders, Skakkebæk, Niels Erik, Brunak, Søren & Meyts, E. R., 1 May 2017, In: Molecular Human Reproduction. 23, 5, p. 339-354 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Comparison of computational methods for the identification of cell cycle-regulated genes

    de Lichtenberg, U., Jensen, L. J., Fausbøll, A., Jensen, T. S., Bork, P. & Brunak, Søren, 2005, In: Bioinformatics. 21, 7, p. 1164-71 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Comorbidity landscape of the Danish patient population affected by chromosome abnormalities

    Jørgensen, Isabella Friis, Russo, F., Jensen, A. B., Westergaard, David, Lademann, M., Hjaltelin, Jessica Xin, Brunak, Søren & Belling, K., 2019, In: Genetics In Medicine. 21, 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Comorbidity landscape of the Danish patient population affected by chromosomal abnormalities

    Russo, F., Jørgensen, Isabella Friis, Westergaard, David, Jensen, A. B., Hjaltelin, Jessica Xin, Belling, K. & Brunak, Søren, 2018, In: European Journal of Human Genetics. 26, p. 697-698

    Research output: Contribution to journal › Conference abstract in journal › Research

  77. Published

    Cometin is a novel neurotrophic factor that promotes neurite outgrowth and neuroblast migration in vitro and supports survival of spiral ganglion neurons in vivo

    Jørgensen, J. R., Fransson, A., Fjord-Larsen, L., Thompson, L. H., Houchins, J. P., Andrade, N., Torp, M., Kalkkinen, N., Andersson, E., Lindvall, O., Ulfendahl, M., Brunak, Søren, Johansen, T. E. & Wahlberg, L. U., 2012, In: Experimental Neurology. 233, 1, p. 172-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Combing the Hairball: Improving Visualization of miRNA-Target Interaction Networks

    Russo, F., Hjaltelin, Jessica Xin, Romero Herrera, J. A. & Brunak, Søren, 2019, MicroRNA Target Identification: Methods and Protocols. Laganà, A. (ed.). Humana Press, p. 279-289 11 p. (Methods in Molecular Biology, Vol. 1970).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  79. Published

    Combined burden and functional impact tests for cancer driver discovery using DriverPower

    Shuai, S., Abascal, F., Amin, S. B., Bader, G. D., Bandopadhayay, P., Barenboim, J., Beroukhim, R., Bertl, J., Boroevich, K. A., Brunak, S., Campbell, P. J., Carlevaro-Fita, J., Chakravarty, D., Chan, C. W. Y., Chen, K., Choi, J. K., Deu-Pons, J., Dhingra, P., Diamanti, K., Feuerbach, L. & 32 others, Fink, J. L., Fonseca, N. A., Frigola, J., Gambacorti-Passerini, C., Garsed, D. W., Gerstein, M., Getz, G., Guo, Q., Gut, I. G., Haan, D., Hamilton, M. P., Haradhvala, N. J., Harmanci, A. O., Helmy, M., Herrmann, C., Hess, J. M., Hobolth, A., Hodzic, E., Hong, C., Hornshøj, H., Isaev, K., Izarzugaza, J. M. G., Johnson, R., Johnson, T. A., Juul, M., Juul, R. I., Kahles, A., Pedersen, J. S., Sidiropoulos, N., Weischenfeldt, Joachim Lütken, PCAWG Drivers and Functional Interpretation Working Group, P. D. A. F. I. W. G. & PCAWG Consortium, P. C., 2020, In: Nature Communications. 11, 1, 12 p., 734.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Combined Ensemble Docking and Machine Learning in Identification of Therapeutic Agents with Potential Inhibitory Effect on Human CES1

    Briand, E., Thomsen, Ragnar, Linnet, Kristian, Rasmussen, H. B., Brunak, Søren & Taboureau, O., 2019, In: Molecules. 24, 15, 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Cohort profile: Copenhagen Hospital Biobank - Cardiovascular Disease Cohort (CHB-CVDC): Construction of a large-scale genetic cohort to facilitate a better understanding of heart diseases

    Laursen, I. H., Banasik, K., Haue, A. D., Petersen, O., Holm, P. C., Westergaard, D., Bundgaard, H., Brunak, S., Frikke-Schmidt, R., Holm, H., Sørensen, E., Thorner, L. W., Larsen, M. A. H., Schwinn, M., Køber, L., Torp-Pedersen, C., Ostrowski, S. R., Erikstrup, C., Nyegaard, M., Stefansson, H. & 11 others, Gylfason, A., Zink, F., Walters, G. B., Oddsson, A., Thorleifsson, G., Masson, G., Thorsteinsdottir, U., Gudbjartsson, D., Pedersen, Ole Birger Vesterager, Stefansson, K. & Ullum, H., 2021, In: BMJ Open. 11, 12, 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Cohort Profile: The Danish Blood Donor Study

    Erikstrup, C., Sørensen, E., Nielsen, K. R., Bruun, M. T., Petersen, M. S., Rostgaard, K., Thørner, L. W., Larsen, M., Mikkelsen, S., Dinh, K. M., Schwinn, M., Rigas, A. S., Didriksen, M., Dowsett, J., von Stemann, J. H., Brodersen, T., Paulsen, I. W., Hindhede, L., Sækmose, S. G., Kaspersen, K. A. & 10 others, Boldsen, J. K., Kjerulff, B., Werge, Thomas, Brunak, Søren, Banasik, Karina, Hansen, Thomas Folkmann, Ullum, H., Hjalgrim, Henrik, Ostrowski, Sisse Rye & Pedersen, Ole Birger Vesterager, 2023, In: International Journal of Epidemiology. 52, 3, p. e162-e171 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Cofactory: Sequence-based prediction of cofactor specificity of Rossmann folds

    Geertz-Hansen, H. M., Blom, N., Feist, A., Brunak, Søren & Petersen, T. N., 13 Feb 2014, In: Proteins: Structure, Function, and Bioinformatics. 82, 9, p. 1819-1828 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Co-evolution of transcriptional and post-translational cell-cycle regulation

    Jensen, L. J., Jensen, T. S., de Lichtenberg, U., Brunak, Søren & Bork, P., 2006, In: Nature Study. 443, 7111, p. 594-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Clonal hematopoiesis and COVID-19 hospitalization in Danish adults

    Burgos Sequeros, C., Tulstrup, M., Bliddal, S., Sørensen, K. M., Nissen, I., Rezahosseini, O., Brooks, P. T., Feenstra, B., Gang, A. O., Geller, F., Hald, A., Harboe, Z. B., Helleberg, M., Jespersen, J. S., Lebech, A. M., Lindegaard, B., Mogensen, T. H., Møller, M. E. E., Nielsen, C. H., Niemann, C. U. & 13 others, Podlekareva, D., Sejdic, A., Sørensen, E., Teglgaard, R. S., Tommerup, Niels, Weis, Nina, Brunak, Søren, Pedersen, Ole Birger Vesterager, Banasik, Karina, Feldt-Rasmussen, Ulla, Nielsen, Susanne Dam, Ostrowski, Sisse Rye & Grønbæk, Kirsten, 2024, In: HemaSphere. 8, 3, 5 p., e58.

    Research output: Contribution to journal › Letter › Research › peer-review

  86. Published

    Clinical, genetic, and experimental increase in soluble urokinase plasminogen activator receptor levels promotes atherosclerosis

    Hindy, G., Tyrrell, D. J., Vasbinder, A., Wei, C., Presswalla, F., Wang, H., Blakely, P. K., Ozel, A. B., Graham, S. E., Holton, G. H., Dowsett, J., Fahed, A. C., Amadi, K-M., Erne, G. K., Tekumulla, A., Ismail, A., Launius, C., Sotoodehnia, N., Pankow, J. S., Thørner, L. W. & 22 others, Erikstrup, C., Pedersen, Ole Birger Vesterager, Banasik, Karina, Brunak, Søren, Ullum, H., Eugen-Olsen, J., Ostrowski, Sisse Rye, Haas, M. E., Nielsen, J. B., Lotta, L. A., Engström, G., Melander, O., Orho-Melander, M., Zhao, L., Murthy, V. L., Pinsky, D. J., Willer, C. J., Heckbert, S. R., Reiser, J., Goldstein, D. R., Desch, K. C. & Hayek, S. S., 2022, In: Journal of Clinical Investigation. 132, 24, 14 p., e158788.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Classification of Left and Right Coronary Arteries in Coronary Angiographies Using Deep Learning

    Eschen, Christian Kim, Banasik, Karina, Christensen, Alex Hørby, Chmura, Piotr Jaroslaw, Pedersen, F., Køber, Lars Valeur, Engstrøm, Thomas, Dahl, A. B., Brunak, Søren & Bundgård, Henning, 2022, In: Electronics (Switzerland). 11, 13, 9 p., 2087.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Circular reasoning rather than cyclic expression

    Jensen, Lars Juhl, de Lichtenberg, U., Jensen, T. S., Brunak, Søren & Bork, P., 2008, In: Genome Biology. 9, 6, p. 403

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Chromosome-wise Protein Interaction Patterns and Their Impact on Functional Implications of Large-Scale Genomic Aberrations

    Kirk, I. K., Weinhold, N., Belling, K., Skakkebæk, Niels Erik, Jensen, T. S., Leffers, H., Juul, Anders & Brunak, Søren, 22 Mar 2017, In: Cell Systems. 4, 3, 11 p., 357-364.e3.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Cholesterol not particle concentration mediates the atherogenic risk conferred by apolipoprotein B particles - A Mendelian randomization analysis

    Helgadottir, A., Thorleifsson, G., Snaebjarnarson, A., Stefansdottir, L., Sveinbjornsson, G., Tragante, V., Björnsson, E., Steinthorsdottir, V., Gretarsdottir, S., Helgason, H., Saemundsdottir, J., Olafsson, I., Thune, J. J., Axelsson Raja, A., Ghouse, J., Olesen, M. S., Christensen, A., Jacobsen, R. L., Dowsett, J., Bruun, M. T. & 18 others, Nielsen, K., Knowlton, K., Nadauld, L., Benediktsson, R., Erikstrup, C., Pedersen, Ole Birger Vesterager, Banasik, Karina, Brunak, Søren, Bundgård, Henning, Ostrowski, Sisse Rye, Sulem, P., Arnar, D. O., Thorgeirsson, G., Thorsteinsdottir, U., Gudbjartsson, D. F., Stefansson, K., Holm, H. & DBDS Genomic Consortium, D. G. C., 2022, In: European Journal of Preventive Cardiology. 29, 18, p. 2374–2385

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    ChemProt-3.0: a global chemical biology diseases mapping

    Kringelum, J. V., Kjærulff, S. K., Brunak, Søren, Lund, O., Oprea, T. I. & Taboureau, O. T., 2016, In: Database: The Journal of Biological Databases and Curation. 2016, 7 p., bav123.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. ChemProt-2.0: visual navigation in a disease chemical biology database

    Kim Kjærulff, S., Wich, L., Kringelum, J., Jacobsen, U. P., Kouskoumvekaki, I., Audouze, K., Lund, O., Brunak, Søren, Oprea, T. I. & Taboureau, O., Jan 2013, In: Nucleic Acids Research. 41, Database issue, p. D464-9

    Research output: Contribution to journal › Journal article › Research

  93. Published

    ChemProt: a disease chemical biology database

    Taboureau, O., Nielsen, S. K., Audouze, K. M. L., Weinhold, N., Edsgärd, D., Roque, F. S., Kouskoumvekaki, I., Bora, A., Curpan, R., Jensen, T. S., Brunak, Søren & Oprea, T., 2011, In: Nucleic Acids Research. 39, Database issue, p. D367-72

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Chance of live birth: a nationwide, registry-based cohort study

    Kolte, A. M., Westergaard, David, Lidegaard, Øjvind, Brunak, Søren & Nielsen, Henriette Svarre, 2021, In: Human Reproduction. 36, 4, p. 1065-1073 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Cancer LncRNA Census reveals evidence for deep functional conservation of long noncoding RNAs in tumorigenesis

    Carlevaro-Fita, J., Lanzós, A., Feuerbach, L., Hong, C., Mas-Ponte, D., Pedersen, J. S., Johnson, R., Sidiropoulos, N., Weischenfeldt, Joachim Lütken & Brunak, Søren, 2020, In: Communications Biology. 3, 1, p. 1-16 56.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease

    Banasik, Karina, Justesen, Johanne Marie, Hornbak, M., Krarup, N. T., Gjesing, A. P., Sandholt, C. H., Søndergaard Jensen, T., Grarup, Niels, Andersson, Åsa, Jørgensen, T., Witte, D. R., Sandbæk, A., Lauritzen, T., Thorens, B., Brunak, Søren, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye & Hansen, Torben, 1 Jan 2011, In: P L o S One. 6, 1, p. e16542

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Benchmarking the HLA typing performance of Polysolver and Optitype in 50 Danish parental trios

    Matey-Hernandez, M. L., Danish Pan Genome Consortium, D. P. G. C., Brunak, Søren, Izarzugaza, J. M. G., Sørensen, L. M., Petersen, Bent, Sibbesen, Jonas Andreas, Liu, S., Belling, K. G., Have, C. T., Bork-Jensen, J., Sun, J., Hansen, Torben, Krogh, Anders, Sørensen, Thorkild I.A., Pedersen, Oluf Borbye, Wang, J., Eiberg, Hans Rudolf Lytchoff & Kristiansen, Karsten, 2018, In: BMC Bioinformatics. 19, p. 1-12 239.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    BALDR: A Web-based platform for informed comparison and prioritization of biomarker candidates for type 2 diabetes mellitus

    Lundgaard, Agnete Troen, Burdet, F., Siggaard, T., Westergaard, David, Vagiaki, D., Cantwell, Lisa, Röder, T., Vistisen, D., Sparsø, T., Giordano, G. N., Ibberson, M., Banasik, Karina & Brunak, Søren, 2023, In: PLOS Computational Biology. 19, 8, 13 p., e1011403.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022

    Saunders, G., Baudis, M., Becker, R., Beltran, S., Béroud, C., Birney, E., Brooksbank, C., Brunak, S., Van den Bulcke, M., Drysdale, R., Capella-Gutierrez, S., Flicek, P., Florindi, F., Goodhand, P., Gut, I., Heringa, J., Holub, P., Hooyberghs, J., Juty, N., Keane, T. M. & 21 others, Korbel, J. O., Lappalainen, I., Leskosek, B., Matthijs, G., Mayrhofer, M. T., Metspalu, A., Navarro, A., Newhouse, S., Nyrönen, T., Page, A., Persson, B., Palotie, A., Parkinson, H., Rambla, J., Salgado, D., Steinfelder, E., Swertz, M. A., Valencia, A., Varma, S., Blomberg, N. & Scollen, S., Nov 2019, In: Nature Reviews. Genetics. 20, 11, p. 702

    Research output: Contribution to journal › Comment/debate › Research

  100. Published

    Associations of ABO and Rhesus D blood groups with phenome-wide disease incidence: A 41-year retrospective cohort study of 482,914 patients

    Bruun-Rasmussen, P., Dziegiel, Morten Hanefeld, Banasik, Karina, Jo­hans­son, Pär In­ge­mar & Brunak, Søren, 2023, In: eLife. 12, 17 p., e83116.

    Research output: Contribution to journal › Journal article › Research › peer-review

Previous 1 2 3 4 Next

ID: 12895347