Kristina Bennet Emdal
Assistant Professor, Special Consultant
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Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.Research output: Contribution to journal › Journal article › Research › peer-review
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Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Emdal, Kristina Bennet & Lundby, Alicia, 2020, In: Molecular & Cellular Oncology. 7, 1, 3 p., e1692643.Research output: Contribution to journal › Comment/debate › Research › peer-review
Characterization of in vivo resistance to osimertinib and JNJ-61186372, an EGFR/Met bispecific antibody, reveals unique and consensus mechanisms of resistance
Emdal, Kristina Bennet, Dittmann, A., Reddy, R. J., Lescarbeau, R. S., Moores, S. L., Laquerre, S. & White, F. M., 1 Nov 2017, In: Molecular Cancer Therapeutics. 16, 11, p. 2572-2585 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
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Differential ultracentrifugation enables deep plasma proteomics through enrichment of extracellular vesicles
Kverneland, Anders Handrup, Østergaard, Ole, Emdal, Kristina Bennet, Svane, Inge Marie & Olsen, Jesper Velgaard, 2023, In: Proteomics. 23, 7-8, 2200039.Research output: Contribution to journal › Journal article › Research › peer-review
Identifying and targeting sporadic oncogenic genetic aberrations in mouse models of triple-negative breast cancer
Liu, H., Murphy, C. J., Karreth, F. A., Emdal, Kristina Bennet, Yang, K., White, F. M., Elemento, O., Toker, A., Wulf, G. M. & Cantley, L. C., 2018, In: Cancer Discovery. 8, 3, p. 354-369 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 33521777
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
271
downloads
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
84
downloads
Molecular switches in signaling networks as a mechanism of action for oncogenic mutations in proximity of tyrosine residues
Research output: Contribution to journal › Comment/debate › Research › peer-review
Published