Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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Analytic framework for peptidomics applied to large-scale neuropeptide identification
Secher, A., Kelstrup, C. D., Conde-Frieboes, K. W., Pyke, C., Raun, K., Wulff, B. S. & Olsen, Jesper Velgaard, 2016, In: Nature Communications. 7, 10 p., 11436.Research output: Contribution to journal › Journal article › Research › peer-review
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Ancient biomolecules reveal ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from Sicily
Scorrano, Gabriele, Nielsen, S. H., Lo Vetro, D., Mackie, Meaghan, Fabbri, P. F., Allentoft, Morten Erik, Martini, F., Martanez-Labarga, C., Rickards, O., Olsen, Jesper Velgaard, Willerslev, Eske, Cappellini, Enrico & Sikora, Martin, 2020, p. 255-255.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave (Sicily, Italy)
Scorrano, Gabriele, Nielsen, Sofie Holtsmark, Vetro, D. L., Sawafuji, R., Mackie, Meaghan, Margaryan, Ashot, Fotaki, Anna Katerina, Martínez-Labarga, C., Fabbri, P. F., Allentoft, Morten Erik, Carra, M., Martini, F., Rickards, O., Olsen, Jesper Velgaard, Pedersen, Mikkel Winther, Cappellini, Enrico & Sikora, Martin, 2022, In: Communications Biology. 5Research output: Contribution to journal › Journal article › Research › peer-review
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Comprehensive Identification of SUMO2/3 Targets and Their Dynamics during Mitosis
Schou, J., Kelstrup, C. D., Hayward, D. G., Olsen, Jesper Velgaard & Nilsson, Jakob, 27 Jun 2014, In: PLOS ONE. 9, 6, p. e100692 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of animal species in skin clothing from museum collections
Schmidt, A. L., Gilbert, M Thomas P, Cappellini, Enrico & Olsen, Jesper Velgaard, 2011. 8 p.Research output: Contribution to conference › Paper › Research › peer-review
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Uncovering SUMOylation Dynamics during Cell-Cycle Progression Reveals FoxM1 as a Key Mitotic SUMO Target Protein
Schimmel, J., Eifler, K., Sigurdsson, J. O., Cuijpers, S. A. G., Hendriks, I. A., Verlaan-de Vries, M., Kelstrup, C. D., Francavilla, C., Medema, R. H., Olsen, Jesper Velgaard & Vertegaal, A. C. O., 20 Mar 2014, In: Molecular Cell. 53, 6, p. 1053-1066Research output: Contribution to journal › Journal article › Research › peer-review
A mass spectrometry-friendly database for cSNP identification
Schandorff, S., Olsen, Jesper Velgaard, Bunkenborg, J., Blagoev, B., Zhang, Y., Andersen, J. S. & Mann, Matthias, 2007, In: Nature Methods. 4, 6, p. 465-6 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic profiling of archaeological human bone
Sawafuji, R., Cappellini, Enrico, Nagaoka, T., Fotaki, Anna Katerina, Jersie-Christensen, R. R., Olsen, Jesper Velgaard, Hirata, K. & Ueda, S., Jun 2017, In: Royal Society Open Science. 4, 6, 12 p., 161004.Research output: Contribution to journal › Journal article › Research › peer-review
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Cylindromatosis Tumor Suppressor Protein (CYLD) Deubiquitinase is Necessary for Proper Ubiquitination and Degradation of the Epidermal Growth Factor Receptor
Sanchez-Quiles, V., Akimov, V., Osinalde, N., Francavilla, C., Puglia, M., Barrio-Hernandez, I., Kratchmarova, I., Olsen, Jesper Velgaard & Blagoev, B., Aug 2017, In: Molecular and Cellular Proteomics. 16, 8, p. 1433-1446 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action
Sampadi, B., Pines, A., Munk, S., Mišovic, B., de Groot, A. J., van de Water, B., Olsen, Jesper Velgaard, Mullenders, L. H. F. & Vrieling, H., 2020, In: Archives of Toxicology. 94, p. 1655-1671 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Divergent Molecular and Cellular Responses to Low and High-Dose Ionizing Radiation
Sampadi, B., Vermeulen, S., Mišovic, B., Boei, J. J., Batth, Tanveer Singh, Chang, J. G., Paulsen, M. T., Magnuson, B., Schimmel, J., Kool, H., Olie, C. S., Everts, B., Vertegaal, A. C. O., Olsen, Jesper Velgaard, Ljungman, M., Jeggo, P. A., Mullenders, L. H. F. & Vrieling, H., 2022, In: Cells. 11, 23, 25 p., 3794.Research output: Contribution to journal › Journal article › Research › peer-review
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ProAlanase is an Effective Alternative to Trypsin for Proteomics Applications and Disulfide Bond Mapping
Samodova, D., Hosfield, C. M., Cramer, C. N., Giuli, M. V., Cappellini, Enrico, Franciosa, Giulia, Rosenblatt, M. M., Kelstrup, C. D. & Olsen, Jesper Velgaard, 2020, In: Molecular & Cellular Proteomics. 19, 12, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SPIN enables high throughput species identification of archaeological bone by proteomics
Rüther, P. L., Husic, I. M., Bangsgaard, Pernille, Gregersen, K. M., Pantmann, P., Carvalho, M., Godinho, R. M., Friedl, L., Cascalheira, J., Taurozzi, Alberto John, Jørkov, M L S, Benedetti, M. M., Haws, J., Bicho, N., Welker, Frido, Cappellini, Enrico & Olsen, Jesper Velgaard, 2022, In: Nature Communications. 13, 14 p., 2458.Research output: Contribution to journal › Journal article › Research › peer-review
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Brain proteome profiling implicates the complement and coagulation cascade in multiple system atrophy brain pathology
Rydbirk, R., Østergaard, O., Folke, J., Hempel, C., DellaValle, B., Andresen, T. L., Løkkegaard, A., Hejl, A-M., Bode, M., Blaabjerg, M., Møller, M., Danielsen, E. H., Salvesen, L., Starhof, C. C., Bech, S., Winge, K., Rungby, J., Pakkenberg, B., Brudek, T., Olsen, J. V. & 1 others, , 2022, In: Cellular and Molecular Life Sciences. 79, 6, 22 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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Expression and secretion of a lytic polysaccharide monooxygenase by a fast-growing cyanobacterium
Russo, D. A., Zedler, J. A. Z., Wittmann, D. N., Möllers, B., Singh, R. K., Batth, Tanveer Singh, van Oort, B., Olsen, Jesper Velgaard, Bjerrum, Morten Jannik & Jensen, Poul Erik, 2019, In: Biotechnology for Biofuels. 12, 1, 13 p., 74.Research output: Contribution to journal › Journal article › Research › peer-review
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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1
Levann, Asha Maria Rudjord, Ye, Z., Hafkenscheid, L., Horn, S., Wiegertjes, R., Nielsen, Mathias Alexander Ingemann, Song, Ming, Mathiesen, C. B. K., Stoop, J., Stowell, S., Straten, P. T., Leffler, H., Vakhrushev, Sergey, Dabelsteen, Sally, Olsen, Jesper Velgaard & Wandall, Hans H., 2023, In: iScience. 26, 7, 21 p., 106984.Research output: Contribution to journal › Journal article › Research › peer-review
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The Role of TTP Phosphorylation in the Regulation of Inflammatory Cytokine Production by MK2/3
Ronkina, N., Shushakova, N., Tiedje, C., Yakovleva, T., Tollenaere, M. A. X., Scott, A., Batth, Tanveer Singh, Olsen, Jesper Velgaard, Helmke, A., Bekker-Jensen, Simon Holst, Clark, A. R., Kotlyarov, A. & Gaestel, M., 2019, In: Journal of immunology (Baltimore, Md. : 1950). 203, 8, p. 2291-2300 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation
Rigbolt, K. T. G., Prokhorova, T., Akimov, V., Løkkegaard, Jeanette, Johansen, P. T., Kratchmarova, I., Kassem, M. S. E., Mann, Matthias, Olsen, Jesper Velgaard & Blagoev, B., 2011, In: Science Signaling. 4, 164, p. rs3Research output: Contribution to journal › Journal article › Research › peer-review
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miR-625-3p regulates oxaliplatin resistance by targeting MAP2K6-p38 signalling in human colorectal adenocarcinoma cells
Rasmussen, M. H., Lyskjær, I., Jersie-Christensen, R. R., Tarpgaard, L. S., Primdal-Bengtson, B., Nielsen, M. M., Pedersen, J. S., Kuhlmann, Tine Plato, Hansen, F., Olsen, Jesper Velgaard, Pfeiffer, P., Ørntoft, T. F. & Andersen, C. L., 2016, In: Nature Communications. 7, 15 p., 12436.Research output: Contribution to journal › Journal article › Research › peer-review
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PRIME-XS, a European infrastructure for proteomics
Raijmakers, R., Olsen, Jesper Velgaard, Aebersold, R. & Heck, A. J. R., 23 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1901-1904 4 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Combinatorial Drug Screening Identifies Ewing Sarcoma–specific Sensitivities
Radic-Sarikas, B., Tsafou, K. P., Emdal, Kristina Bennet, Papamarkou, T., Huber, K. V. M., Mutz, C., Toretsky, J. A., Bennett, K. L., Olsen, Jesper Velgaard, Brunak, S., Kovar, H. & Superti-Furga, G., Jan 2017, In: Molecular Cancer Therapeutics. 16, 1, p. 88-101 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immature truncated O-glycophenotype of cancer directly induces oncogenic features
Radhakrishnan, P., Dabelsteen, S., Madsen, F. B., Francavilla, C., Kopp, K. L., Steentoft, C., Vakhrushev, S. Y., Olsen, J. V., Hansen, L., Bennett, E. P., Woetmann, A., Yin, G., Chen, L., Song, H., Bak, M., Hlady, R. A., Peters, S. L., Opavsky, R., Thode, C., Qvortrup, K. & 4 others, , 12 Aug 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 39, p. e4066-e4077 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Palaeoproteomics resolves sloth relationships
Presslee, S., Slater, G. J., Pujos, F., Forasiepi, A. M., Fischer, R., Molloy, K., Mackie, M., Olsen, J. V., Kramarz, A., Taglioretti, M., Scaglia, F., Lezcano, M., Lanata, J. L., Southon, J., Feranec, R., Bloch, J., Hajduk, A., Martin, F. M., Salas Gismondi, R., Reguero, M. & 6 others, , 2019, In: Nature Ecology & Evolution. 3, p. 1121-1130Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative proteomics characterization of acutely isolated primary adult rat cardiomyocytes and fibroblasts
Poulsen, P. C., Schrölkamp, Maren, Bagwan, N., Leurs, U., Humphries, E. S. A., Bomholzt, S. H., Nielsen, Morten Schak, Bentzen, Bo Hjorth, Olsen, Jesper Velgaard & Lundby, Alicia, 2020, In: Journal of Molecular and Cellular Cardiology. 143, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability
Pladevall Morera, David, Munk, S., Ingham, Andreas, Garribba, L., Albers, E., Liu, Ying, Olsen, Jesper Velgaard & Lopez-Contreras, Andres, 2019, In: Nucleic Acids Research. 47, 15, p. 8004-8018 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A comprehensive platform for the analysis of ubiquitin-like protein modifications using in vivo biotinylation
Pirone, L., Xolalpa, W., Sigurdsson, J. O., Ramirez, J., Pérez, C., González, M., de Sabando, A. R., Elortza, F., Rodriguez, M. S., Mayor, U., Olsen, Jesper Velgaard, Barrio, R. & Sutherland, J. D., 2017, In: Scientific Reports. 7, 17 p., 40756.Research output: Contribution to journal › Journal article › Research › peer-review
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The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA
Pinto, R., Vågbø, C. B., Jakobsson, M. E., Kim, Y., Baltissen, M. P., O'Donohue, M., Hernández Guzmán, Ulises, Małecki, J. M., Wu, J., Kirpekar, F., Olsen, Jesper Velgaard, Gleizes, P., Vermeulen, M., Leidel, S. A., Slupphaug, G. & Falnes, P. Ø., 2020, In: Nucleic Acids Research. 48, 2, p. 830-846 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global phosphoproteome profiling reveals unanticipated networks responsive to cisplatin treatment of embryonic stem cells
Pines, A., Kelstrup, C. D., Vrouwe, M. G., Puigvert, J. C., Typas, D., Misovic, B., de Groot, A., von Stechow, L., van de Water, B., Danen, E. H. J., Vrieling, H., Mullenders, L. H. F. & Olsen, Jesper Velgaard, 2011, In: Molecular and Cellular Biology. 31, 24, p. 4964-77 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
SUMO modification of the ubiquitin-conjugating enzyme E2-25K
Pichler, A., Knipscheer, P., Oberhofer, E., van Dijk, W. J., Körner, R., Olsen, Jesper Velgaard, Jentsch, S., Melchior, F. & Sixma, T. K., 2005, In: Nature Structural and Molecular Biology. 12, 3, p. 264-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KIT(D816V) Induces SRC-Mediated Tyrosine Phosphorylation of MITF and Altered Transcription Program in Melanoma
Phung, B., Kazi, J. U., Lundby, Alicia, Bergsteinsdottir, K., Sun, J., Goding, C. R., Jönsson, G., Olsen, Jesper Velgaard, Steingrímsson, E. & Rönnstrand, L., 2017, In: Molecular cancer research : MCR. 15, 9, p. 1265-1274 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimizing Linear Ion-Trap Data-Independent Acquisition toward Single-Cell Proteomics
Phlairaharn, T., Ye, Z., Krismer, Elena, Pedersen, A. K., Pietzner, M., Olsen, Jesper Velgaard, Schoof, E. M. & Searle, B. C., 2023, In: Analytical Chemistry. 95, 26, p. 9881-9891 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
Pfeiffer, A., Franciosa, Giulia, Locard-Paulet, Marie, Piga, I., Reckzeh, K., Vemulapalli, V., Blacklow, S. C., Theilgaard-Mønch, Kim, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2022, In: Cancer Research. 82, 11, p. 2141-2155 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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B-lymphoid tyrosine kinase (Blk) is an oncogene and a potential target for therapy with Dasatinib in cutaneous T-cell lymphoma (CTCL)
Petersen, D. L., Krejsgaard, T., Berthelsen, J., Fredholm, S., Willerslev-Olsen, A., Sibbesen, N. A., Bonefeld, Charlotte Menne, Andersen, M. H., Francavilla, C., Olsen, Jesper Velgaard, Hu, T., Zhang, M., Wasik, M. A., Geisler, Carsten, Woetmann, Anders & Ødum, Niels, 12 Jun 2014, In: Leukemia. 28, p. 2109-12 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
Pedersen, A., Pfeiffer, A., Karemore, G., Akimov, V., Bekker-Jensen, D. B., Blagoev, B., Francavilla, C. & Olsen, Jesper Velgaard, 2021, In: iScience. 24, 4, 34 p., 102321.Research output: Contribution to journal › Journal article › Research › peer-review
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The ubiquitin ligase Cullin5SOCS2 regulates NDR1/STK38 stability and NF-κB transactivation
Paul, I., Batth, Tanveer Singh, Iglesias Gato, Diego, Al-Araimi, A., Al-Haddabi, I., Alkharusi, A., Norstedt, G., Olsen, Jesper Velgaard, Zadjali, F. & Flores-Morales, A., 2017, In: Scientific Reports. 7, 14 p., 42800.Research output: Contribution to journal › Journal article › Research › peer-review
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Repurposing the antipsychotic drug amisulpride for targeting synovial fibroblast activation in arthritis
Papadopoulou, D., Roumelioti, F., Tzaferis, C., Chouvardas, P., Pedersen, A., Charalampous, F., Christodoulou-Vafeiadou, E., Ntari, L., Karagianni, N., Denis, M. C., Olsen, Jesper Velgaard, Matralis, A. N. & Kollias, G., 2023, In: JCI insight. 8, 9, 18 p., e165024.Research output: Contribution to journal › Journal article › Research › peer-review
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Global effects of kinase inhibitors on signaling networks revealed by quantitative phosphoproteomics
Pan, C., Olsen, Jesper Velgaard, Daub, H. & Mann, Matthias, 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2796-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors
Pan, C., Gnad, F., Olsen, Jesper Velgaard & Mann, Matthias, 2008, In: Proteomics. 8, 21, p. 4534-46 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recalibrating Equus evolution using the genome sequence of an early Middle Pleistocene horse
Orlando, L. A. A., Ginolhac, A., Zhang, G., Froese, D., Albrechtsen, A., Stiller, M., Schubert, M., Cappellini, E., Petersen, B., Moltke, I., Johnson, P. L. F., Fumagalli, M., Mouatt, J. T. V., Raghavan, M., Korneliussen, T. S., Malaspinas, A. S., Vogt, J., Szklarczyk, D. M., Kelstrup, C., Vinther, J. & 36 others, , 4 Jul 2013, In: Nature. 499, 7456, p. 74-78 5 p.Research output: Contribution to journal › Letter › Research › peer-review
Large-scale proteomics analysis of the human kinome
Oppermann, F. S., Gnad, F., Olsen, Jesper Velgaard, Hornberger, R., Greff, Z., Kéri, G., Mann, M. & Daub, H., 2009, In: Molecular and Cellular Proteomics. 8, 7, p. 1751-64 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids
Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In: Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain
Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Higher-energy C-trap dissociation for peptide modification analysis
Olsen, Jesper Velgaard, Macek, B., Lange, O., Makarov, A., Horning, S. & Mann, Matthias, 2007, In: Nature Methods. 4, 9, p. 709-12 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative proteomic profiling of membrane proteins from the mouse brain cortex, hippocampus, and cerebellum using the HysTag reagent: mapping of neurotransmitter receptors and ion channels
Olsen, Jesper Velgaard, Nielsen, P. A., Andersen, J. R., Mann, Matthias & Wisniewski, J. R., 2007, In: Brain Research. 1134, 1, p. 95-106 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Trypsin cleaves exclusively C-terminal to arginine and lysine residues
Olsen, Jesper Velgaard, Ong, S. & Mann, Matthias, 2004, In: Molecular and Cellular Proteomics. 3, 6, p. 608-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks
Olsen, Jesper Velgaard, Blagoev, B., Gnad, F., Macek, B., Kumar, C., Mortensen, P. & Mann, Matthias, 2006, In: Cell. 127, 3, p. 635-48 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
Parts per million mass accuracy on an Orbitrap mass spectrometer via lock mass injection into a C-trap
Olsen, Jesper Velgaard, de Godoy, L. M. F., Li, G., Macek, B., Mortensen, P., Pesch, R., Makarov, A., Lange, O., Horning, S. & Mann, Matthias, 2005, In: Molecular and Cellular Proteomics. 4, 12, p. 2010-21 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Improved peptide identification in proteomics by two consecutive stages of mass spectrometric fragmentation
Olsen, Jesper Velgaard & Mann, Matthias, 2004, In: Proceedings of the National Academy of Science of the United States of America. 101, 37, p. 13417-22 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
A dual pressure linear ion trap orbitrap instrument with very high sequencing speed
Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis
Olsen, Jesper Velgaard, Vermeulen, M., Santamaria, A., Kumar, C., Miller, M. L., Jensen, Lars Juhl, Gnad, F., Cox, J., Jensen, T. S., Nigg, E. A., Brunak, Søren & Mann, Matthias, 2010, In: Science Signaling. 3, 104, p. ra3 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9925376
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Molecular basis of Tousled-Like Kinase 2 activation
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52 Genetic Loci Influencing Myocardial Mass
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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