Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
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Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Tsafou, K. P., Horn, H., Lindner, S., Schulte, J. H., Eggert, A., Jensen, Lars Juhl, Francavilla, C. & Olsen, Jesper Velgaard, 2015, In: Science Signaling. 8, 374, ra40.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrated proximal proteomics reveals IRS2 as a determinant of cell survival in ALK-driven neuroblastoma
Emdal, Kristina Bennet, Pedersen, A., Bekker-Jensen, D. B., Lundby, Alicia, Claeys, S., De Preter, K., Speleman, F., Francavilla, C. & Olsen, Jesper Velgaard, 20 Nov 2018, In: Science Signaling. 11, 557, p. 1-17 17 p., eaap9752.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
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Digging deeper into ancient skeletal proteomes through consecutive digestion with multiple proteases
Fagernäs, Zandra Selina, Troché, Gaudry Bruno, Olsen, Jesper Velgaard & Welker, Frido, 2024, In: Journal of Proteomics. 298, 10 p., 105143.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteogenomic characterization of patient-derived xenografts highlights the role of REST in neuroendocrine differentiation of castration-resistant prostate cancer
Flores-Morales, A., Bergmann, T. B., Lavallee, C., Batth, T. S., Lin, D., Lerdrup, M., Friis, S., Bartels, A., Kristensen, G., Krzyzanowska, A., Xue, H., Fazli, L., Hansen, K., Røder, M. A., Brasso, K., Moreira, J. M., Bjartell, A., Wang, Y., Olsen, J. V., Collins, C. C. & 1 others, , 2019, In: Clinical Cancer Research. 25, 2, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
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Control of endothelial cell tube formation by Notch ligand intracellular domain interactions with activator protein 1 (AP-1)
Forghany, Z., Robertson, F., Lundby, Alicia, Olsen, Jesper Velgaard & Baker, D. A., 2018, In: Journal of Biological Chemistry. 293, 4, p. 1229-1242 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-omic detection of Mycobacterium leprae in archaeological human dental calculus
Fotaki, Anna Katerina, Denham, S. D., Mackie, Meaghan, Iraeta Orbegozo, Miren, Mylopotamitaki, Dorothea, Gopalakrishnan, Shyam, Sicheritz-Pontén, Thomas, Olsen, Jesper Velgaard, Cappellini, Enrico, KU, thw266, Christophersen, A., Gilbert, M Thomas P & Vågene, Åshild Joanne, 2020, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 375, 1812, 10 p., 20190584.Research output: Contribution to journal › Journal article › Research › peer-review
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SILAC-Based Temporal Phosphoproteomics
Francavilla, C., Hekmat, O., Blagoev, B. & Olsen, Jesper Velgaard, 2014, Stable Isotope Labeling by Amino Acids in Cell Culture (SILAC): Methods and Protocols. Warscheid, B. (ed.). Vol. 1188. p. 125-48 24 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
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Functional Proteomics Defines the Molecular Switch Underlying FGF Receptor Trafficking and Cellular Outputs
Francavilla, C., Rigbolt, K. T. G., Emdal, Kristina Bennet, Carraro, G., Vernet, E., Bekker-Jensen, D. B., Streicher, W., Wikström, M., Sundström, M., Bellusci, S., Cavallaro, U., Blagoev, B. & Olsen, Jesper Velgaard, 26 Sep 2013, In: Molecular Cell. 51, 6, p. 707-22 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking
Francavilla, C., Papetti, M., Rigbolt, K. T. G., Pedersen, A., Sigurdsson, J. O., Cazzamali, G., Karemore, G., Blagoev, B. & Olsen, Jesper Velgaard, Jun 2016, In: Nature Structural and Molecular Biology. 23, 6, p. 608–618 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Phosphoproteomics of Primary Cells Reveals Druggable Kinase Signatures in Ovarian Cancer
Francavilla, C., Lupia, M., Tsafou, K., Villa, A., Kowalczyk, K., Rakownikow Jersie-Christensen, R., Bertalot, G., Confalonieri, S., Brunak, Søren, Jensen, Lars Juhl, Cavallaro, U. & Olsen, Jesper Velgaard, 28 Mar 2017, In: Cell Reports. 18, 13, p. 3242-3256 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Recent advances in kinase signaling network profiling by mass spectrometry
Franciosa, Giulia, Locard-Paulet, Marie, Jensen, Lars Juhl & Olsen, Jesper Velgaard, 2023, In: Current Opinion in Chemical Biology. 73, 11 p., 102260.Research output: Contribution to journal › Review › Research › peer-review
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Impact of SHP2 tyrosine phosphorylation on the development of acquired resistance to allosteric SHP2 inhibitors
Franciosa, Giulia & Olsen, Jesper Velgaard, 2023, In: OncoTarget. 14, p. 281-283 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Proteomics to study cancer immunity and improve treatment
Franciosa, Giulia, Kverneland, Anders Handrup, Jensen, Agnete Witness Præst, dqp123, dqp123 & Olsen, Jesper Velgaard, 2023, In: Seminars in Immunopathology. 45, 11 p., 241–251.Research output: Contribution to journal › Review › Research › peer-review
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Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures
Franciosa, Giulia, Smits, J. G. A., Minuzzo, S., Martinez Del Val, Ana, Indraccolo, S. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 19 p., 2507.Research output: Contribution to journal › Journal article › Research › peer-review
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Deciphering the human phosphoproteome
Franciosa, Giulia, Martinez-Val, A. & Olsen, Jesper Velgaard, 2020, In: Nature Biotechnology. 38, p. 285-286 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells
Galli, G. G., Carrara, M., Francavilla, C., Honnens de Lichtenberg, K., Olsen, Jesper Velgaard, Calogero, R. A. & Lund, Anders H., 16 Sep 2013, In: Molecular and Cellular Biology.Research output: Contribution to journal › Journal article › Research › peer-review
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Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High-accuracy identification and bioinformatic analysis of in vivo protein phosphorylation sites in yeast
Gnad, F., de Godoy, L. M. F., Cox, J., Neuhauser, N., Ren, S., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Proteomics. 9, 20, p. 4642-4652 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
PHOSIDA (phosphorylation site database): management, structural and evolutionary investigation, and prediction of phosphosites
Gnad, F., Ren, S., Cox, J., Olsen, Jesper Velgaard, Macek, B., Oroshi, M. & Mann, Matthias, 2007, In: Genome Biology. 8, 11, p. R250Research output: Contribution to journal › Journal article › Research › peer-review
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway
Gruhler, A., Olsen, Jesper Velgaard, Mohammed, S., Mortensen, P., Faergeman, N. J., Mann, Matthias & Jensen, O. N., 2005, In: Molecular and Cellular Proteomics. 4, 3, p. 310-27 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of N-terminal acetyltransferase A activity induces thermally unstable ribosomal proteins and increases their turnover in Saccharomyces cerevisiae
Hernández Guzmán, Ulises, Aksnes, H., Ree, R., Krogh, Nicolai, Jakobsson, M. E., Jensen, Lars Juhl, Arnesen, T. & Olsen, Jesper Velgaard, 2023, In: Nature Communications. 14, 4517.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Ultra-fast label-free quantification and comprehensive proteome coverage with narrow-window data-independent acquisition
Guzman, U. H., Martinez Del Val, A., Ye, Z., Damoc, E., Arrey, T. N., Pashkova, A., Renuse, S., Denisov, E., Petzoldt, J., Peterson, A. C., Harking, F., Østergaard, O., Rydbirk, R., Aznar, S., Stewart, H., Xuan, Y., Hermanson, D., Horning, S., Hock, C., Makarov, A. & 2 others, , 2024, (E-pub ahead of print) In: Nature Biotechnology.Research output: Contribution to journal › Journal article › Research › peer-review
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FRMD6 has tumor suppressor functions in prostate cancer
Haldrup, J., Strand, S. H., Cieza-Borrella, C., Jakobsson, M. E., Riedel, M., Norgaard, M., Hedensted, S., Dagnaes-Hansen, F., Ulhoi, B. P., Eeles, R., Borre, M., Olsen, Jesper Velgaard, Thomsen, M., Kote-Jarai, Z. & Sorensen, K. D., 2021, In: Oncogene. 40, p. 763-776 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic lineage priming is driven via direct enhancer regulation by ERK
Hamilton, W. B., Mosesson, Y., S. Monteiro, Rita, Emdal, Kristina Bennet, Knudsen, Teresa Emmilie Toudal, Francavilla, C., Barkai, N., Olsen, Jesper Velgaard & Brickman, Joshua Mark, 2019, In: Nature. 575, p. 355-360Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9925376
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Molecular basis of Tousled-Like Kinase 2 activation
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52 Genetic Loci Influencing Myocardial Mass
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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