Jesper Velgaard Olsen
Professor, Deputy Head of Centre, Professor
- 2020
- Published
Quantitative phosphoproteomics to unravel the cellular response to chemical stressors with different modes of action
Sampadi, B., Pines, A., Munk, S., Mišovic, B., de Groot, A. J., van de Water, B., Olsen, Jesper Velgaard, Mullenders, L. H. F. & Vrieling, H., 2020, In: Archives of Toxicology. 94, p. 1655-1671 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ancient biomolecules reveal ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from Sicily
Scorrano, Gabriele, Nielsen, S. H., Lo Vetro, D., Mackie, Meaghan, Fabbri, P. F., Allentoft, Morten Erik, Martini, F., Martanez-Labarga, C., Rickards, O., Olsen, Jesper Velgaard, Willerslev, Eske, Cappellini, Enrico & Sikora, Martin, 2020, p. 255-255.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Genomic and proteomic evidence for Mycobacterium leprae in human medieval dental calculus from Trondheim, Norway
Vagene, A. J., Fotaki, Anna Katerina, Denham, S. D., Orbegozo, M., Mackie, Meaghan, Olsen, Jesper Velgaard, Cappellini, Enrico, Christophersen, A. & Gilbert, M Thomas P, 2020, In: American Journal of Physical Anthropology. 171, p. 291 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
Vind, Anna Constance, Snieckute, Goda, Blasius, Melanie, Tiedje, C., Krogh, Nicolai, Bekker-Jensen, D. B., Andersen, Kasper Langebjerg, Nordgaard, C., Tollenaere, M. A. X., Lund, Anders H., Olsen, Jesper Velgaard, Nielsen, Henrik & Bekker-Jensen, Simon Holst, 2020, In: Molecular Cell. 78, 4, p. 700-713.E7Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dental proteome of Homo antecessor: {with Author Correction]
Welker, F., Ramos-Madrigal, J., Gutenbrunner, P., Mackie, M., Tiwary, S., Rakownikow Jersie-Christensen, R., Chiva, C., Dickinson, M. R., Kuhlwilm, M., de Manuel, M., Gelabert, P., Martinón-Torres, M., Margvelashvili, A., Arsuaga, J. L., Carbonell, E., Marques-Bonet, T., Penkman, K., Sabidó, E., Cox, J., Olsen, J. V. & 6 others, , Apr 2020, In: Nature. 580, 7802, p. 235-238 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
The methyltransferase METTL9 mediates pervasive 1-methylhistidine modification in mammalian proteomes
Davydova, E., Shimazu, T., Schuhmacher, M. K., Jakobsson, M. E., Willemen, H. L. D. M., Liu, T., Moen, A., Ho, A. Y. Y., Małecki, J., Schroer, L., Pinto, R., Suzuki, T., Grønsberg, I. A., Sohtome, Y., Akakabe, M., Weirich, S., Kikuchi, M., Olsen, J. V., Dohmae, N., Umehara, T. & 8 others, , 2021, In: Nature Communications. 12, 14 p., 891.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Causal integration of multi-omics data with prior knowledge to generate mechanistic hypotheses
Dugourd, A., Kuppe, C., Sciacovelli, M., Gjerga, E., Gabor, A., Emdal, Kristina Bennet, Vieira, V., Bekker-Jensen, D. B., Kranz, J., Bindels, E. M. J., Costa, A. S. H., Sousa, A., Beltrao, P., Rocha, M., Olsen, Jesper Velgaard, Frezza, C., Kramann, R. & Saez-Rodriguez, J., 2021, In: Molecular Systems Biology. 17, 1, 17 p., e9730.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures
Franciosa, Giulia, Smits, J. G. A., Minuzzo, S., Martinez Del Val, Ana, Indraccolo, S. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 19 p., 2507.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FRMD6 has tumor suppressor functions in prostate cancer
Haldrup, J., Strand, S. H., Cieza-Borrella, C., Jakobsson, M. E., Riedel, M., Norgaard, M., Hedensted, S., Dagnaes-Hansen, F., Ulhoi, B. P., Eeles, R., Borre, M., Olsen, Jesper Velgaard, Thomsen, M., Kote-Jarai, Z. & Sorensen, K. D., 2021, In: Oncogene. 40, p. 763-776 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
Jones, M. J. K., Gelot, C., Munk, S., Koren, A., Kawasoe, Y., George, K. A., Santos, R. E., Olsen, Jesper Velgaard, McCarroll, S. A., Frattini, M. G., Takahashi, T. S. & Jallepalli, P. V., 2021, In: Molecular Cell. 81, 3, p. 426-441.e8 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GHB analogs confer neuroprotection through specific interaction with the CaMKIIα hub domain
Leurs, U., Klein, A. B., McSpadden, E. D., Griem-Krey, N., Solbak, S. M. Ø., Houlton, J., Villumsen, I. S., Vogensen, S. B., Hamborg, L., Gauger, S. J., Palmelund, L. B., Larsen, A. S. G., Shehata, M. A., Kelstrup, C. D., Olsen, J. V., Bach, A., Burnie, R. O., Kerr, D. S., Gowing, E. K., Teurlings, S. M. W. & 9 others, , 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31, 9 p., e2108079118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteome comparison of human hearts with those of model organisms
Linscheid, N., Santos, A., Poulsen, P. C., Mills, Robert William, Callø, Kirstine, Leurs, U., Ye, J. Z., Stolte, C., Thomsen, Morten Bækgaard, Bentzen, Bo Hjorth, Lundegaard, Pia Rengtved, Olesen, Morten Steen Salling, Jensen, Lars Juhl, Olsen, Jesper Velgaard & Lundby, Alicia, 2021, In: PLOS Biology. 19, 4, 22 p., e3001144.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2 Feb 2021, bioRxiv, p. 1-34, 34 p.Research output: Working paper › Preprint
- Published
Data Processing and Analysis for DIA-Based Phosphoproteomics Using Spectronaut
Martinez Del Val, Ana, Bekker-Jensen, D. B., Hogrebe, A. & Olsen, Jesper Velgaard, 2021, Proteomics Data Analysis. Cecconi, D. (ed.). Springer, p. 95-107 13 p. (Methods in Molecular Biology, Vol. 2361).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution
Martinez Del Val, Ana, Bekker-Jensen, D. B., Steigerwald, S., Koenig, Claire, Østergaard, Ole, Mehta, A., Tran, T., Sikorski, K., Torres Vega, Estefania, Kwasniewicz, E., Brynjólfsdóttir, S. H., Frankel, Lisa, Kjøbsted, Rasmus, Krogh, Nicolai, Lundby, Alicia, Bekker-Jensen, Simon Holst, Lund-Johansen, F. & Olsen, Jesper Velgaard, 2021, In: Nature Communications. 12, 1, 17 p., 7113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human METTL18 is a histidine-specific methyltransferase that targets RPL3 and affects ribosome biogenesis and function
Małecki, J. M., Odonohue, M., Kim, Y., Jakobsson, M. E., Gessa, L., Pinto, R., Wu, J., Davydova, E., Moen, A., Olsen, Jesper Velgaard, Thiede, B., Gleizes, P., Leidel, S. A. & Falnes, P. Ø., 2021, In: Nucleic Acids Research. 49, 6, p. 3185-3203 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of the golgi apparatus by p38 and JNK kinases during cellular stress responses
Nordgaard, C., Tollenaere, M. A. X., Martinez Del Val, Ana, Bekker-Jensen, D. B., Blasius, Melanie, Olsen, Jesper Velgaard & Bekker-Jensen, Simon Holst, 2021, In: International Journal of Molecular Sciences. 22, 17, 23 p., 9595.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic investigation of Cbl and Cbl-b in neuroblastoma cell differentiation highlights roles for SHP-2 and CDK16
Pedersen, A., Pfeiffer, A., Karemore, G., Akimov, V., Bekker-Jensen, D. B., Blagoev, B., Francavilla, C. & Olsen, Jesper Velgaard, 2021, In: iScience. 24, 4, 34 p., 102321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Faecal proteomics as a novel method to study mammalian behaviour and physiology
Tsutaya, T., Mackie, Meaghan, Sawafuji, R., Miyabe-Nishiwaki, T., Olsen, Jesper Velgaard & Cappellini, Enrico, 2021, In: Molecular Ecology Resources. 21, 6, p. 1808-1819 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A Middle Pleistocene Denisovan molar from the Annamite Chain of northern Laos
Demeter, F., Zanolli, C., Westaway, K. E., Joannes-Boyau, R., Duringer, P., Morley, M. W., Welker, F., Rüther, P. L., Skinner, M. M., McColl, H., Gaunitz, C., Vinner, L., Dunn, T. E., Olsen, J. V., Sikora, M., Ponche, J-L., Suzzoni, E., Frangeul, S., Boesch, Q., Antoine, P-O. & 20 others, , 2022, In: Nature Communications. 13, 17 p., 2557.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phosphoproteomics of primary AML patient samples reveals rationale for AKT combination therapy and p53 context to overcome selinexor resistance
Emdal, Kristina Bennet, Palacio-Escat, N., Wigerup, C., Eguchi, A., Nilsson, H., Bekker-Jensen, D. B., Rönnstrand, L., Kazi, J. U., Puissant, A., Itzykson, R., Saez-Rodriguez, J., Masson, K., Blume-Jensen, P. & Olsen, Jesper Velgaard, 2022, In: Cell Reports. 40, 6, 25 p., 111177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THO complex deficiency impairs DNA double-strand break repair via the RNA surveillance kinase SMG-1
Kamp, J. A., Lemmens, B. B. L. G., Romeijn, R. J., González-Prieto, R., Olsen, Jesper Velgaard, Vertegaal, A. C. O., van Schendel, R. & Tijsterman, M., 2022, In: Nucleic Acids Research. 50, 11, p. 6235-6250 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimal analytical strategies for sensitive and quantitative phosphoproteomics using TMT-based multiplexing
Koenig, Claire, Martinez-Val, A., Franciosa, Giulia & Olsen, Jesper Velgaard, 2022, In: Proteomics. 22, 19-20, 13 p., 2100245.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combining mass spectrometry and machine learning to discover bioactive peptides
Madsen, C. T., Refsgaard, J. C., Teufel, F. G., Kjærulff, S. K., Wang, Z., Meng, G., Jessen, C., Heljo, P., Jiang, Q., Zhao, X., Wu, B., Zhou, X., Tang, Y., Jeppesen, J. F., Kelstrup, C. D., Buckley, S. T., Tullin, S., Nygaard-Jensen, J., Chen, X., Zhang, F. & 4 others, , 2022, In: Nature Communications. 13, 17 p., 6235.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The feasibility of palaeoproteomics for studying ancient hominins from South Africa
Madupe, Palesa Petunia, Hlazo, N., Ruther, P. L., Mackie, Meaghan, Welker, Frido, Ramos Madrigal, Jazmin, Patramanis, Ioannis, Racimo, Fernando, Schroeder, L., Olsen, Jesper Velgaard, Ackermann, R. R. & Cappellini, Enrico, 2022, In: American journal of biological anthropology. 177, S73, p. 112 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
ID: 9925376
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Molecular basis of Tousled-Like Kinase 2 activation
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52 Genetic Loci Influencing Myocardial Mass
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Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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