Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
- 2013
- Published
Effectiveness of a coordinated and tailored return-to-work intervention for sickness absence beneficiaries with mental health problems
Martin, M., Nielsen, Michael Lund, Madsen, I., Petersen, S., Lange, Theis & Rugulies, R., 2013, In: Journal of Occupational Rehabilitation. 23, 4, p. 621-30 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension
Leeming, D. J., Karsdal, M. A., Byrjalsen, I., Bendtsen, Flemming, Trebicka, J., Nielsen, Michael Lund, Christiansen, C., Møller, Søren & Krag, A., 2013, In: Alimentary Pharmacology and Therapeutics. 38, 9, p. 1086-1096 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-DNA sequence differences spell genetic code ambiguities
Bentin, Thomas & Nielsen, Michael Lund, 2013, In: Artificial DNA. 2, 3, p. 69-70 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry
Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, Michael Lund, 2013, In: Journal of Proteome Research. 12, 2, p. 1020-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Advances in characterizing ubiquitylation sites by mass spectrometry
Sylvestersen, K. B., Young, C. & Nielsen, Michael Lund, 5 Jan 2013, In: Current Opinion in Chemical Biology. 17, 1, p. 49-58 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDK-mediated activation of the SCF(FBXO) (28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer
Cepeda, D., Ng, H-F., Sharifi, H. R., Mahmoudi, S., Cerrato, V. S., Fredlund, E., Magnusson, K., Nilsson, H., Malyukova, A., Rantala, J., Klevebring, D., Viñals, F., Bhaskaran, N., Zakaria, S. M., Rahmanto, A. S., Grotegut, S., Nielsen, M. L., Szigyarto, C. A-K., Sun, D., Lerner, M. & 10 others, , 3 Jul 2013, In: E M B O Molecular Medicine (Online). 5, 7, p. 1067-1086 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis
Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide Identification of Poly(ADP-Ribosyl)ation Targets in Different Genotoxic Stress Responses
Jungmichel, S., Rosenthal, F., Altmeyer, M., Lukas, Jiri, Hottiger, M. O. & Nielsen, Michael Lund, 24 Oct 2013, In: Molecular Cell. 52, 2, p. 272-285 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Tousled-like kinases phosphorylate Asf1 to promote histone supply during DNA replication
Kamalyukova, I. M., Young, C., Strømme, C. B., Ménard, Patrice, Jasencakova, Zuzana, Mejlvang, J., Ask, K., Ploug, Michael, Nielsen, Michael Lund, Jensen, O. N. & Groth, Anja, 2014, In: Nature Communications. 5, p. 3394Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification
Tessarz, P., Santos-Rosa, H., Robson, S. C., Sylvestersen, K. B., Nelson, C. J., Nielsen, Michael Lund & Kouzarides, T., 23 Jan 2014, In: Nature. 505, p. 564-568Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein Interaction Screening for the Ankyrin Repeats and Suppressor of Cytokine Signaling (SOCS) Box (ASB) Family Identify Asb11 as a Novel Endoplasmic Reticulum Resident Ubiquitin Ligase
Andresen, C. A., Smedegaard, S., Sylvestersen, K. B., Svensson, C., Iglesias Gato, Diego, Cazzamali, G., Nielsen, T. K., Nielsen, Michael Lund & Flores Morales, A., 24 Jan 2014, In: The Journal of Biological Chemistry. 289, 4, p. 2043-2054 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Specificity and commonality of the phosphoinositide-binding proteome analyzed by quantitative mass spectrometry
Jungmichel, S., Sylvestersen, K. B., Choudhary, Chunaram, Nguyen, S., Mann, Matthias & Nielsen, Michael Lund, 13 Feb 2014, In: Cell Reports. 6, 3, p. 578-91 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest
Sylvestersen, K. B., Horn, H., Jungmichel, S., Jensen, Lars Juhl & Nielsen, Michael Lund, 21 Feb 2014, In: Molecular & Cellular Proteomics. 13, p. 2072-2088 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Citrullination regulates pluripotency and histone H1 binding to chromatin
Christophorou, M. A., Castelo-Branco, G., Halley-Stott, R. P., Oliveira, C. S., Loos, R., Radzisheuskaya, A., Mowen, K. A., Bertone, P., Silva, J. C. R., Zernicka-Goetz, M., Nielsen, Michael Lund, Gurdon, J. B. & Kouzarides, T., 6 Mar 2014, In: Nature. 507, p. 104-108Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical utility of mass spectral binning in proteomic experiments by SPectral Immonium Ion Detection (SPIID)
Kelstrup, C. D., Freese, C., Heck, A. J. R., Olsen, Jesper Velgaard & Nielsen, Michael Lund, 3 Jun 2014, In: Molecular & Cellular Proteomics. 13, 8, p. 1914-1924 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The NBS1-Treacle complex controls ribosomal RNA transcription in response to DNA damage
Larsen, D. H., Hari, F., Clapperton, J. A., Gwerder, M., Gutsche, K., Altmeyer, M., Jungmichel, S., Toledo Lazaro, L. I., Fink, D., Rask, M., Grøfte, M., Lukas, Claudia, Nielsen, Michael Lund, Smerdon, S. J., Lukas, Jiri & Stucki, M., Aug 2014, In: Nature Cell Biology. 16, 8, p. 792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
A two-step protein quality control pathway for a misfolded DJ-1 variant in fission yeast
Mathiassen, S. G., Larsen, I. B., Poulsen, E. G., Madsen, C. T., Papaleo, E., Lindorff-Larsen, Kresten, Kragelund, Birthe Brandt, Nielsen, Michael Lund, Kriegenburg, F. & Hartmann-Petersen, Rasmus, 2015, In: The Journal of Biological Chemistry. 290, 34, p. 21141-21153 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
Madsen, C. T., Sylvestersen, K. B., Young, C., Buch-Larsen, Sara Charlotte, Poulsen, J. W., Andersen, M. A., Palmqvist, E. A., Hey-Mogensen, M., Jensen, P. B., Treebak, Jonas Thue, Lisby, Michael & Nielsen, Michael Lund, 2015, In: Nature Communications. 6, 12 p., 7726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Direct neuronal glucose uptake Heralds activity-dependent increases in cerebral metabolism
Lundgaard, I., Li, B., Xie, L., Kang, H., Sanggaard, S., Haswell, J. D. R., Sun, W., Goldman, S., Blekot, S., Nielsen, Michael Lund, Takano, T., Deane, R. & Nedergaard, Maiken, 2015, In: Nature Communications. 6, 12 p., 6807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In: Nature Communications. 6, p. 1-12 8088.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Large-Scale Identification of the Arginine Methylome by Mass Spectrometry
Sylvestersen, K. B. & Nielsen, Michael Lund, 2 Nov 2015, Current Protocols in Protein Science. Vol. 82. 17 p. (Current Protocols in Protein Science).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2016
- Published
Proteome-wide analysis of arginine monomethylation reveals widespread occurrence in human cells
Buch-Larsen, Sara Charlotte, Sylvestersen, K. B., Mund, Andreas, Lyon, D., Mullari, M., Madsen, M. V., Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 30 Aug 2016, In: Science Signaling. 9, 443, 14 p., rs9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide identification of the endogenous ADP-ribosylome of mammalian cells and tissue
Martello, R., Leutert, M., Jungmichel, S., Bilan, V., Buch-Larsen, Sara Charlotte, Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 1 Oct 2016, In: Nature Communications. 7, 13 p., 12917.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Bekker-Jensen, D. B., Kelstrup, C. D., Batth, Tanveer Singh, Buch-Larsen, Sara Charlotte, Haldrup, C., Bramsen, J. B., Sørensen, K. D., Høyer, S., Ørntoft, T. F., Andersen, C. L., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2017, In: Cell Systems. 4, 6, p. 587-599, e1-e4 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Citrullination modulates oligodendrocyte differentiation
Falcao, A., Meijer, M., Rinwa, P., Cummings, T., Varas, M., Liang, J., Casaccia, P., Christophorou, M., Nielsen, Michael Lund, Ernfors, P. & Castelo-Branco, G., 2017, In: Glia. 65, S1, p. E389 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Proteome-Wide Identification of In Vivo ADP-Ribose Acceptor Sites by Liquid Chromatography-Tandem Mass Spectrometry
Buch-Larsen, Sara Charlotte, Leutert, M., Bilan, V., Martello, R., Jungmichel, S., Young, C., Hottiger, M. O. & Nielsen, Michael Lund, 2017, Poly(ADP-Ribose) Polymerase. Tulin, A. V. (ed.). Humana Press, Vol. 1608. p. 149-162 14 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Specifying RNA-Binding Regions in Proteins by Peptide Cross-Linking and Affinity Purification
Mullari, M., Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2017, In: Journal of Proteome Research. 16, 8, p. 2762-2772 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation
Hendriks, Ivo Alexander, Lyon, D., Young, C., Jensen, Lars Juhl, Vertegaal, A. C. O. & Nielsen, Michael Lund, Mar 2017, In: Nature Structural and Molecular Biology. 24, 3, p. 325-336 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved Reversed Phase Chromatography of Hydrophilic Peptides from Spatial and Temporal Changes in Column Temperature
Young, C., Podtelejnikov, A. V. & Nielsen, Michael Lund, 2 Jun 2017, In: Journal of Proteome Research. 16, 6, p. 2307-2317 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling
Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Arginine Methylation by PRMT2 Controls the Functions of the Actin Nucleator Cobl
Hou, W., Nemitz, S., Schopper, S., Nielsen, Michael Lund, Kessels, M. M. & Qualmann, B., 2018, In: Developmental Cell. 45, 2, p. 262-275.E8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana, Blanca, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In: Cell Reports. 23, 7, p. 2211-2224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Site-specific characterization of endogenous SUMOylation across species and organs
Hendriks, Ivo Alexander, Lyon, D., Su, D., Skotte, Niels Henning, Daniel, J. A., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Nature Communications. 9, p. 1-17 2456.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide Analysis of Serine ADP-Ribosylation Reveals Widespread Occurrence and Site-Specific Overlap with Phosphorylation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lyon, D., Jensen, Lars Juhl & Nielsen, Michael Lund, 2018, In: Cell Reports. 24, 9, p. 2493-2505Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
An advanced strategy for comprehensive profiling of ADP-ribosylation sites using mass spectrometry-based proteomics
Hendriks, Ivo Alexander, Buch-Larsen, Sara Charlotte & Nielsen, Michael Lund, 2019, In: Molecular and Cellular Proteomics. 18, 5, p. 1010-1026Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Citrullination of HP1γ chromodomain affects association with chromatin
Wiese, M., Bannister, A. J., Basu, S., Boucher, W., Wohlfahrt, K., Christophorou, M. A., Nielsen, Michael Lund, Klenerman, D., Laue, E. D. & Kouzarides, T., 2019, In: Epigenetics & Chromatin. 12, 17 p., 21.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In: Experimental Cell Research. 381, 1, p. 129-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination
Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In: Cell Reports. 27, 4, p. 1090-1102.e10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of GLI1 by cis DNA elements and epigenetic marks
Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, Michael Lund, Leong, K., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P., 2019, In: DNA Repair. 79, p. 10-21 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SUMOylation promotes protective responses to DNA-protein crosslinks
Borgermann, N., Ackermann, Leena, Schwertman, P., Hendriks, Ivo Alexander, Thijssen, K., Liu, Julio, Lans, H., Nielsen, Michael Lund & Mailand, Niels, 2019, In: E M B O Journal. 38, 17 p., e101496.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells
Theurillat, I., Hendriks, Ivo Alexander, Cossec, J., Andrieux, A., Nielsen, Michael Lund & Dejean, A., 2020, In: Cell Reports. 32, 11, 20 p., 108146.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lodge, J. M., Rykaer, M., Furtwängler, Benjamin, Shishkova, E., Westphall, M. S., Coon, J. J. & Nielsen, Michael Lund, 2020, In: Cell Reports. 32, 12, 17 p., 108176.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites
Guerillon, Claire Aline, Smedegaard, S., Hendriks, Ivo Alexander, Nielsen, Michael Lund & Mailand, Niels, 2020, In: Journal of Biological Chemistry. 295, p. 8350-8362Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treacle controls the nucleolar response to rDNA breaks via TOPBP1 recruitment and ATR activation
Mooser, C., Symeonidou, I., Leimbacher, P., Ribeiro, A., Shorrocks, A. K., Jungmichel, S., Buch-Larsen, Sara Charlotte, Knechtle, K., Jasrotia, A., Zurbriggen, D., Jeanrenaud, A., Leikauf, C., Fink, D., Nielsen, Michael Lund, Blackford, A. N. & Stucki, M., 2020, In: Nature Communications. 11, 16 p., 123.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Applicability of Small-Molecule Inhibitors in the Study of Peptidyl Arginine Deiminase 2 (PAD2) and PAD4
Martín Monreal, M. T., Stripp, Alexandra, Massarenti, Laura, Mondal, S., Šenolt, L., Ødum, Niels, Nielsen, Michael Lund, Thompson, P. R., Nielsen, Claus Henrik & Damgaard, D., 2021, In: Frontiers in Immunology. 12, 11 p., 716250.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets
Rodriguez, K. M., Buch-Larsen, Sara Charlotte, Kirby, I. T., Siordia, I. R., Hutin, D., Rasmussen, M., Grant, D. M., David, L. L., Matthews, J., Nielsen, Michael Lund & Cohen, M. S., 2021, In: eLife. 10, 35 p., e60480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNAJC9 integrates heat shock molecular chaperones into the histone chaperone network
Hammond, Colin, Bao, H., Hendriks, Ivo Alexander, Carraro, Massimo, García-Nieto, A., Liu, Y., Reveron-Gomez, Nazaret, Spanos, C., Chen, L., Rappsilber, J., Nielsen, Michael Lund, Patel, D. J., Huang, H. & Groth, Anja, 2021, In: Molecular Cell. 81, 12, p. 2533-2548Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa
Liu, C., Wu, T., Shu, X., Li, S., Wang, D. R., Wang, N., Zhou, R., Yang, H., Jiang, H., Hendriks, Ivo Alexander, Gong, P., Zhang, L., Nielsen, Michael Lund, Li, K., Wang, L. & Yang, B., 2021, In: Advanced Biology. 5, 3, 11 p., 2000308.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MaxQuant. Live Enables Enhanced Selectivity and Identification of Peptides Modified by Endogenous SUMO and Ubiquitin
Hendriks, Ivo Alexander, Akimov, V., Blagoev, B. & Nielsen, Michael Lund, 2021, In: Journal of Proteome Research. 20, 4, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13143239
Most downloads
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488
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
292
downloads
An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
252
downloads
Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
Research output: Contribution to journal › Journal article › Research › peer-review
Published