Michael Lund Nielsen

Michael Lund Nielsen

Professor

ORCID: 0000-0002-0067-9039

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  1. Published

    PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

    Đukić, N., Strømland, Ø., Elsborg, J. D., Munnur, D., Zhu, K., Schuller, M., Chatrin, C., Kar, P., Duma, L., Suyari, O., Rack, J. G. M., Baretić, D., Crudgington, D. R. K., Groslambert, J., Fowler, G., Wijngaarden, S., Prokhorova, E., Rehwinkel, J., Schüler, H., Filippov, D. V. & 5 others, Sanyal, S., Ahel, D., Nielsen, Michael Lund, Smith, R. & Ahel, I., 2023, In: Science Advances. 9, 37, 19 p., eadi2687.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

    de Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, Michael Lund, Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M., 2008, In: Nature. 455, 7217, p. 1251-4 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Identification of dominant signaling pathways from proteomics expression data

    Zubarev, R. A., Nielsen, Michael Lund, Fung, E. M., Savitski, M. M., Kel-Margoulis, O., Wingender, E. & Kel, A., 2008, In: Journal of Proteomics. 71, 1, p. 89-96 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Tandem ionization mass spectrometry of biomolecules

    Zubarev, R. A., Nielsen, Michael Lund & Budnik, B. A., 2000, In: European Journal of Mass Spectrometry. 6, 3, p. 235-240 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Toward error-free proteomics

    Zubarev, R., Nielsen, Michael Lund, Savitski, M. & Kocher, T., 2005, In: Molecular and Cellular Proteomics. 4, 8, p. S16-S16

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Waves of sumoylation support transcription dynamics during adipocyte differentiation

    Zhao, X., Hendriks, Ivo Alexander, Le Gras, S., Ye, T., Ramos-Alonso, L., Nguea P, A., Lien, G. F., Ghasemi, F., Klungland, A., Jost, B., Enserink, J. M., Nielsen, Michael Lund & Chymkowitch, P., 2022, In: Nucleic Acids Research. 50, 3, p. 1351-1369 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling

    Zhang, G., Kruse, Thomas, López-Méndez, B., Sylvestersen, K. B., Garvanska, Dimitriya Hristoforova, Schopper, S., Nielsen, Michael Lund & Nilsson, Jakob, 12 Jun 2017, In: Nature Communications. 8, 12 p., 15822.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Improved Reversed Phase Chromatography of Hydrophilic Peptides from Spatial and Temporal Changes in Column Temperature

    Young, C., Podtelejnikov, A. V. & Nielsen, Michael Lund, 2 Jun 2017, In: Journal of Proteome Research. 16, 6, p. 2307-2317 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Citrullination of HP1γ chromodomain affects association with chromatin

    Wiese, M., Bannister, A. J., Basu, S., Boucher, W., Wohlfahrt, K., Christophorou, M. A., Nielsen, Michael Lund, Klenerman, D., Laue, E. D. & Kouzarides, T., 2019, In: Epigenetics & Chromatin. 12, 17 p., 21.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

    Webby, C. J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., Nielsen, Michael Lund, Schmitz, C., Butler, D. S., Yates, J. R., Delahunty, C. M., Hahn, P., Lengeling, A., Mann, M., Proudfoot, N. J., Schofield, C. J. & Boettger, A., 2009, In: Science. 325, 5936, p. 90-93 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Site-specific phosphorylation of PSD-95 dynamically regulates the postsynaptic density as observed by phase separation

    Vistrup-Parry, M., Chen, X., Johansen, T. L., Bach, S., Buch-Larsen, Sara Charlotte, Bartling, Christian Reinhard Otto, Ma, C., Clemmensen, L. S., Nielsen, Michael Lund, Zhang, M. & Strømgaard, Kristian, 2021, In: iScience. 24, 11, 103268.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

    Vesterlund, M., Zadjali, F., Persson, T., Nielsen, Michael Lund, Kessler, B. M., Norstedt, G. & Flores Morales, A., 1 Jan 2011, In: P L o S One. 6, 9, p. e25358 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Extensive SUMO Modification of Repressive Chromatin Factors Distinguishes Pluripotent from Somatic Cells

    Theurillat, I., Hendriks, Ivo Alexander, Cossec, J., Andrieux, A., Nielsen, Michael Lund & Dejean, A., 2020, In: Cell Reports. 32, 11, 20 p., 108146.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification

    Tessarz, P., Santos-Rosa, H., Robson, S. C., Sylvestersen, K. B., Nelson, C. J., Nielsen, Michael Lund & Kouzarides, T., 23 Jan 2014, In: Nature. 505, p. 564-568

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Regulation of GLI1 by cis DNA elements and epigenetic marks

    Taylor, R., Long, J., Yoon, J. W., Childs, R., Sylvestersen, K. B., Nielsen, Michael Lund, Leong, K., Iannaccone, S., Walterhouse, D. O., Robbins, D. J. & Iannaccone, P., 2019, In: DNA Repair. 79, p. 10-21 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Proteomic analysis of arginine methylation sites in human cells reveals dynamic regulation during transcriptional arrest

    Sylvestersen, K. B., Horn, H., Jungmichel, S., Jensen, Lars Juhl & Nielsen, Michael Lund, 21 Feb 2014, In: Molecular & Cellular Proteomics. 13, p. 2072-2088 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Large-Scale Identification of the Arginine Methylome by Mass Spectrometry

    Sylvestersen, K. B. & Nielsen, Michael Lund, 2 Nov 2015, Current Protocols in Protein Science. Vol. 82. 17 p. (Current Protocols in Protein Science).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  21. Published

    Advances in characterizing ubiquitylation sites by mass spectrometry

    Sylvestersen, K. B., Young, C. & Nielsen, Michael Lund, 5 Jan 2013, In: Current Opinion in Chemical Biology. 17, 1, p. 49-58 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism

    Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana, Blanca, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In: Cell Reports. 23, 7, p. 2211-2224 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    SCAI promotes error-free repair of DNA interstrand crosslinks via the Fanconi anemia pathway

    Schubert, Lisa, Hendriks, Ivo Alexander, Hertz, Emil Peter Thrane, Wu, Wei, Sellés Baiget, Selene, Hoffmann, Saskia, Bagge, Keerthana Stine Viswalingam, Gallina, I., Pentakota, S., Benedict, Bente, Johansen, Joachim, Apelt, K., Luijsterburg, M. S., Rasmussen, Simon, Lisby, Michael, Liu, Ying, Nielsen, Michael Lund, Mailand, Niels & Duxin, Julien, 2022, In: EMBO Reports. 23, 4, 20 p., e53639.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of The American Society for Mass Spectrometry. 18, 1, p. 113-120 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund, Garbuzynskiy, S. O., Galzitskaya, O. V., Surin, A. K. & Zubarev, R. A., 2007, In: Angewandte Chemie International Edition. 46, 9, p. 1481-1484 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Angewandte Chemie International Edition. 45, 32, p. 5301-5303 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Side-chain losses in electron capture dissociation to improve peptide identification

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Analytical Chemistry. 79, 6, p. 2296-2302 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 7, p. 2669-2673 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Proteomics-grade de novo sequencing approach

    Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F. & Zubarev, R. A., 2005, In: Journal of Proteome Research. 4, 6, p. 2348-2354 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Shifted-basis technique improves accuracy of peak position determination in Fourier transform mass spectrometry

    Savitski, M. M., Ivonin, I. A., Nielsen, Michael Lund, Zubarev, R. A., Tsybin, Y. O. & Hakansson, P., 2004, In: Journal of The American Society for Mass Spectrometry. 15, 4, p. 457-461 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 935-948 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. New data base-independent, sequence tag-based scoring of peptide MS/MS data validates Mowse scores, recovers below threshold data, singles out modified peptides, and assesses the quality of MS/MS techniques

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2005, In: Molecular and Cellular Proteomics. 4, 8, p. 1180-1188 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells

    Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In: Experimental Cell Research. 381, 1, p. 129-138 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Electrospray ionization tandem mass spectrometry sequencing of novel skin peptides from Ranid frogs containing disulfide bridges

    Samgina, T., Arternenko, K., Gorshkov, V., Lebedev, A., Nielsen, Michael Lund, Savitski, M. & Zubarev, R., 2007, In: European Journal of Mass Spectrometry. 13, 2, p. 155-163 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Chemical genetics and proteome-wide site mapping reveal cysteine MARylation by PARP-7 on immune-relevant protein targets

    Rodriguez, K. M., Buch-Larsen, Sara Charlotte, Kirby, I. T., Siordia, I. R., Hutin, D., Rasmussen, M., Grant, D. M., David, L. L., Matthews, J., Nielsen, Michael Lund & Cohen, M. S., 2021, In: eLife. 10, 35 p., e60480.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Regulation of Rad52-dependent replication fork recovery through serine ADP-ribosylation of PolD3

    Richards, F., Llorca-Cardenosa, M. J., Langton, J., Buch-Larsen, Sara Charlotte, Shamkhi, N. F., Sharma, A. B., Nielsen, Michael Lund & Lakin, N. D., 2023, In: Nature Communications. 14, 1, 14 p., 4310.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Characterizing citrullination by mass spectrometry-based proteomics

    Stripp, Alexandra, Hendriks, Ivo Alexander & Nielsen, Michael Lund, 2023, In: Philosophical transactions of the Royal Society of London. Series B, Biological sciences. 378, 1890, 14 p., 20220237.

    Research output: Contribution to journal › Review › Research › peer-review

  38. E-pub ahead of print

    A quantitative and site-specific atlas of the citrullinome reveals widespread existence of citrullination and insights into PADI4 substrates

    Stripp, Alexandra, Hendriks, Ivo Alexander, Elsborg, Jonas Damgaard, Buch-Larsen, Sara Charlotte, Nielsen, C. H., Terslev, L., Kirsch, Rebecca, Damgaard, D., Doncheva, Nadezhda Tsankova, Lennartsson, Caroline Linnea Elin, Rykær, M., Jensen, Lars Juhl, Christophorou, M. A. & Nielsen, Michael Lund, 2024, (E-pub ahead of print) In: Nature Structural and Molecular Biology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Experiences and perspectives of MALDI MS and MS/MS in proteomic research

    Rappsilber, J., Moniatte, M., Nielsen, Michael Lund, Podtelejnikov, A. V. & Mann, M., 2003, In: International Journal of Mass Spectrometry. 226, 1, p. 223-237 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Unrestrained poly-ADP-ribosylation provides insights into chromatin regulation and human disease

    Prokhorova, E., Agnew, T., Wondisford, A. R., Tellier, M., Kaminski, N., Beijer, D., Holder, J., Groslambert, J., Suskiewicz, M. J., Zhu, K., Reber, J. M., Krassnig, S. C., Palazzo, L., Murphy, S., Nielsen, Michael Lund, Mangerich, A., Ahel, D., Baets, J., O'Sullivan, R. J. & Ahel, I., 2021, In: Molecular Cell. 81, 12, p. 2640-2655

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Serine-linked PARP1 auto-modification controls PARP inhibitor response

    Prokhorova, E., Zobel, F., Smith, R., Zentout, S., Gibbs-Seymour, I., Schützenhofer, K., Peters, A., Groslambert, J., Zorzini, V., Agnew, T., Brognard, J., Nielsen, Michael Lund, Ahel, D., Huet, S., Suskiewicz, M. J. & Ahel, I., 2021, In: Nature Communications. 12, 1, 12 p., 4055.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Using guanidine-hydrochloride for fast and efficient protein digestion and single-step affinity-purification mass spectrometry

    Poulsen, J. W., Madsen, C. T., Young, C., Poulsen, F. M. & Nielsen, Michael Lund, 2013, In: Journal of Proteome Research. 12, 2, p. 1020-30 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Comprehensive profiling of proteome changes upon sequential deletion of deubiquitylating enzymes

    Poulsen, J. W., Madsen, C. T., Young, C., Kelstrup, C. D., Grell, H. C., Henriksen, P., Jensen, Lars Juhl & Nielsen, Michael Lund, 2012, In: Journal of Proteomics. 75, 13, p. 3886-97 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Comparison of electron capture dissociation and collisionally activated dissociation of polycations of peptide nucleic acids

    Olsen, Jesper Velgaard, Haselmann, K. F., Nielsen, Michael Lund, Budnik, B. A., Nielsen, P. E. & Zubarev, R. A., 2001, In: Rapid Communications in Mass Spectrometry. 15, 12, p. 969-74 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. HysTag--a novel proteomic quantification tool applied to differential display analysis of membrane proteins from distinct areas of mouse brain

    Olsen, Jesper Velgaard, Andersen, J. R., Nielsen, P. A., Nielsen, Michael Lund, Figeys, D., Mann, Matthias & Wisniewski, J. R., Jan 2004, In: Molecular and Cellular Proteomics. 3, 1, p. 82-92 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

    Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Extent of modifications in human proteome samples and their effect on dynamic range of analysis in shotgun proteomics

    Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2006, In: Molecular and Cellular Proteomics. 5, 12, p. 2384-2391 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Peptide end sequencing by orthogonal MALDI tandem mass spectrometry

    Nielsen, Michael Lund, Bennett, K. L., Larsen, B., Moniatte, M. & Mann, M., 2002, In: Journal of Proteome Research. 1, 1, p. 63-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Tandem MALDI/El ionization for tandem Fourier transform ion cyclotron resonance mass spectrometry of polypeptides

    Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F. & Zubarev, R. A., 2003, In: International Journal of Mass Spectrometry. 226, 1, p. 181-187 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 13143239