Michael Lund Nielsen

Michael Lund Nielsen

Professor


  1. 2012
  2. Published

    Proteomic analyses reveal divergent ubiquitylation site patterns in murinetissues

    Wagner, S. A., Beli, P., Weinert, B. T., Schölz, C. F., Kelstrup, C. D., Young, C., Nielsen, Michael Lund, Olsen, Jesper Velgaard, Brakebusch, Cord Herbert & Choudhary, Chunaram, 2012, In: Molecular & Cellular Proteomics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2011
  4. Published

    A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

    Wagner, S. A., Beli, P., Weinert, B. T., Nielsen, Michael Lund, Cox, J., Mann, Matthias & Choudhary, Chunaram, 1 Oct 2011, In: Molecular and Cellular Proteomics. 10, 10, p. M111.013284

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level

    Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The SOCS2 Ubiquitin Ligase Complex Regulates Growth Hormone Receptor Levels

    Vesterlund, M., Zadjali, F., Persson, T., Nielsen, Michael Lund, Kessler, B. M., Norstedt, G. & Flores Morales, A., 1 Jan 2011, In: P L o S One. 6, 9, p. e25358 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. ATP Enhances Neuronal Differentiation of PC12 Cells by Activating PKC alpha Interactions with Cytoskeletal Proteins

    Marin-Vicente, C., Guerrero-Valero, M., Nielsen, Michael Lund, Savitski, M. M., Gomez-Fernandez, J. C., Zubarev, R. A. & Corbalan-Garcia, S., 2011, In: Journal of Proteome Research. 10, 2, p. 529-540 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2009
  9. A dual pressure linear ion trap orbitrap instrument with very high sequencing speed

    Olsen, Jesper Velgaard, Schwartz, J. C., Griep-Raming, J., Nielsen, Michael Lund, Damoc, E., Denisov, E., Lange, O., Remes, P., Taylor, D., Splendore, M., Wouters, E. R., Senko, M., Makarov, A., Mann, Matthias & Horning, S., 2009, In: Molecular and Cellular Proteomics. 8, 12, p. 2759-69 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Analysis of in vivo histone methylation kinetics by Heavy Methyl SILAC

    Bonaldi, T., Vitale, E., Nielsen, Michael Lund, Cox, J. & Mann, M., 2009, In: Amino Acids. 37, p. 66 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing

    Webby, C. J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., Nielsen, Michael Lund, Schmitz, C., Butler, D. S., Yates, J. R., Delahunty, C. M., Hahn, P., Lengeling, A., Mann, M., Proudfoot, N. J., Schofield, C. J. & Boettger, A., 2009, In: Science. 325, 5936, p. 90-93 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Lysine acetylation targets protein complexes and co-regulates major cellular functions

    Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 2008
  14. Analytical Utility of Small Neutral Losses from Reduced Species in Electron Capture Dissociation Studied Using SwedECD Database

    Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2008, In: Analytical Chemistry. 80, 21, p. 8089-8094 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast

    de Godoy, L. M. F., Olsen, J. V., Cox, J., Nielsen, Michael Lund, Hubner, N. C., Fröhlich, F., Walther, T. C. & Mann, M., 2008, In: Nature. 455, 7217, p. 1251-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Identification of dominant signaling pathways from proteomics expression data

    Zubarev, R. A., Nielsen, Michael Lund, Fung, E. M., Savitski, M. M., Kel-Margoulis, O., Wingender, E. & Kel, A., 2008, In: Journal of Proteomics. 71, 1, p. 89-96 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Immunoaffinity enrichments followed by mass spectrometric detection for studying global protein tyrosine phosphorylation

    Lind, S. B., Molin, M., Savitski, M. M., Emilsson, L., Astrom, J., Hedberg, L., Adams, C., Nielsen, Michael Lund, Engstrom, A., Elfineh, L., Andersson, E., Zubarev, R. A. & Pettersson, U., 2008, In: Journal of Proteome Research. 7, 7, p. 2897-2910 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry

    Nielsen, Michael Lund, Vermeulen, M., Bonaldi, T., Cox, J., Moroder, L. & Mann, M., 2008, In: Nature Methods. 5, 6, p. 459-460 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2007
  20. Backbone carbonyl group basicities are related to gas-phase fragmentation of peptides and protein folding

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund, Garbuzynskiy, S. O., Galzitskaya, O. V., Surin, A. K. & Zubarev, R. A., 2007, In: Angewandte Chemie International Edition. 46, 9, p. 1481-1484 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. De novo peptide sequencing and identification with precision mass spectrometry

    Frank, A. M., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Pevzner, P. A., 2007, In: Journal of Proteome Research. 6, 1, p. 114-123 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Electrospray ionization tandem mass spectrometry sequencing of novel skin peptides from Ranid frogs containing disulfide bridges

    Samgina, T., Arternenko, K., Gorshkov, V., Lebedev, A., Nielsen, Michael Lund, Savitski, M. & Zubarev, R., 2007, In: European Journal of Mass Spectrometry. 13, 2, p. 155-163 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Hydrogen rearrangement to and from radical z fragments in electron capture dissociation of peptides

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of The American Society for Mass Spectrometry. 18, 1, p. 113-120 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein

    Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In: Analyst. 132, 8, p. 768-776 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Relative specificities of water and ammonia losses from backbone fragments in collision-activated dissociation

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 7, p. 2669-2673 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Side-chain losses in electron capture dissociation to improve peptide identification

    Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2007, In: Analytical Chemistry. 79, 6, p. 2296-2302 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. SwedCAD, a database of annotated high-mass accuracy MS/MS spectra of tryptic peptides

    Falth, M., Savitski, M. M., Nielsen, Michael Lund, Kjeldsen, F., Andren, P. E. & Zubarev, R. A., 2007, In: Journal of Proteome Research. 6, 10, p. 4063-4067 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. The RBCC gene RFP2 (leu5) encodes a novel transmembrane E3 ubiquitin ligase involved in ERAD

    Lerner, M., Corcoran, M., Cepeda, D., Nielsen, Michael Lund, Zubarev, R., Ponten, F., Uhlen, M., Hober, S., Grander, D. & Sangfelt, O., 2007, In: Molecular Biology of the Cell. 18, 5, p. 1670-1682 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2006
  30. Complementary sequence preferences of electron-capture dissociation and vibrational excitation in fragmentation of polypeptide polycations

    Savitski, M. M., Kjeldsen, F., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Angewandte Chemie International Edition. 45, 32, p. 5301-5303 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Extent of modifications in human proteome samples and their effect on dynamic range of analysis in shotgun proteomics

    Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2006, In: Molecular and Cellular Proteomics. 5, 12, p. 2384-2391 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 13143239