Michael Lund Nielsen
Professor
Nielsen Group
Blegdamsvej 3B
2200 København N
Improving protein identification using complementary fragmentation techniques in Fourier transform mass spectrometry
Nielsen, Michael Lund, Savitski, M. M. & Zubarev, R. A., 2005, In: Molecular and Cellular Proteomics. 4, 6, p. 835-845 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
Skotte, Niels Henning, Andersen, Jens Velde, Santos, A., Aldana, Blanca, Willert, C. W., Nørremølle, Anne, Waagepetersen, Helle S. & Nielsen, Michael Lund, 2018, In: Cell Reports. 23, 7, p. 2211-2224 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells
Samudyata, Amaral, P. P., Engström, P. G., Robson, S. C., Nielsen, Michael Lund, Kouzarides, T. & Castelo-Branco, G., 2019, In: Experimental Cell Research. 381, 1, p. 129-138 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
Intramolecular hydrogen atom transfer in hydrogen-deficient polypeptide radical cations
Nielsen, Michael Lund, Budnik, B. A., Haselmann, K. F., Olsen, Jesper Velgaard & Zubarev, R. A., 2000, In: Chemical Physics Letters. 330, 5-6, p. 558-562 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry
Nielsen, Michael Lund, Vermeulen, M., Bonaldi, T., Cox, J., Moroder, L. & Mann, M., 2008, In: Nature Methods. 5, 6, p. 459-460 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
Jmjd6 Catalyses Lysyl-Hydroxylation of U2AF65, a Protein Associated with RNA Splicing
Webby, C. J., Wolf, A., Gromak, N., Dreger, M., Kramer, H., Kessler, B., Nielsen, Michael Lund, Schmitz, C., Butler, D. S., Yates, J. R., Delahunty, C. M., Hahn, P., Lengeling, A., Mann, M., Proudfoot, N. J., Schofield, C. J. & Boettger, A., 2009, In: Science. 325, 5936, p. 90-93 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Large-Scale Identification of the Arginine Methylome by Mass Spectrometry
Sylvestersen, K. B. & Nielsen, Michael Lund, 2 Nov 2015, Current Protocols in Protein Science. Vol. 82. 17 p. (Current Protocols in Protein Science).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Liquid chromatography at critical conditions: Comprehensive approach to sequence-dependent retention time prediction
Gorshkov, A. V., Tarasova, I. A., Evreinov, V. V., Savitski, M. M., Nielsen, Michael Lund, Zubarev, R. A. & Gorshkov, M. V., 2006, In: Analytical Chemistry. 78, 22, p. 7770-7777 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)
Altmeyer, M., Neelsen, K. J., Teloni, F., Pozdnyakova, I., Pellegrino, S., Grøfte, M., Rask, M. D., Streicher, W., Jungmichel, S., Nielsen, Michael Lund & Lukas, Jiri, 19 Aug 2015, In: Nature Communications. 6, p. 1-12 8088.Research output: Contribution to journal › Journal article › Research › peer-review
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Lysine acetylation targets protein complexes and co-regulates major cellular functions
Choudhary, Chunaram, Kumar, C., Gnad, F., Nielsen, Michael Lund, Rehman, M., Walther, T. C., Olsen, Jesper Velgaard & Mann, Matthias, 2009, In: Science. 325, 5942, p. 834-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mapping Physiological ADP-Ribosylation Using Activated Ion Electron Transfer Dissociation
Buch-Larsen, Sara Charlotte, Hendriks, Ivo Alexander, Lodge, J. M., Rykaer, M., Furtwängler, Benjamin, Shishkova, E., Westphall, M. S., Coon, J. J. & Nielsen, Michael Lund, 2020, In: Cell Reports. 32, 12, 17 p., 108176.Research output: Contribution to journal › Journal article › Research › peer-review
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Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level
Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590Research output: Contribution to journal › Journal article › Research › peer-review
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MaxQuant. Live Enables Enhanced Selectivity and Identification of Peptides Modified by Endogenous SUMO and Ubiquitin
Hendriks, Ivo Alexander, Akimov, V., Blagoev, B. & Nielsen, Michael Lund, 2021, In: Journal of Proteome Research. 20, 4, p. 2042-2055 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mechanism and function of DNA replication-independent DNA-protein crosslink repair via the SUMO-RNF4 pathway
Liu, Julio, Kühbacher, U., Larsen, N. B., Borgermann, N., Garvanska, Dimitriya Hristoforova, Hendriks, Ivo Alexander, Ackermann, Leena, Haahr, Peter Thorlund, Gallina, I., Guérillon, C., Branigan, E., Hay, R. T., Azuma, Y., Nielsen, Michael Lund, Duxin, Julien & Mailand, Niels, 2021, In: E M B O Journal. 40, 21 p., e107413.Research output: Contribution to journal › Journal article › Research › peer-review
ModifiComb, a new proteomic tool for mapping substoichiometric post-translational modifications, finding novel types of modifications, and fingerprinting complex protein mixtures
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Molecular and Cellular Proteomics. 5, 5, p. 935-948 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multisite SUMOylation restrains DNA polymerase η interactions with DNA damage sites
Guerillon, Claire Aline, Smedegaard, S., Hendriks, Ivo Alexander, Nielsen, Michael Lund & Mailand, Niels, 2020, In: Journal of Biological Chemistry. 295, p. 8350-8362Research output: Contribution to journal › Journal article › Research › peer-review
New data base-independent, sequence tag-based scoring of peptide MS/MS data validates Mowse scores, recovers below threshold data, singles out modified peptides, and assesses the quality of MS/MS techniques
Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2005, In: Molecular and Cellular Proteomics. 4, 8, p. 1180-1188 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel serological neo-epitope markers of extracellular matrix proteins for the detection of portal hypertension
Leeming, D. J., Karsdal, M. A., Byrjalsen, I., Bendtsen, Flemming, Trebicka, J., Nielsen, Michael Lund, Christiansen, C., Møller, Søren & Krag, A., 2013, In: Alimentary Pharmacology and Therapeutics. 38, 9, p. 1086-1096 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
On studying protein phosphorylation patterns using bottom-up LC-MS/MS: the case of human alpha-casein
Kjeldsen, F., Savitski, M. M., Nielsen, Michael Lund, Shi, L. & Zubarev, R. A., 2007, In: Analyst. 132, 8, p. 768-776 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Optimized Fast and Sensitive Acquisition Methods for Shotgun Proteomics on a Quadrupole Orbitrap Mass Spectrometer
Kelstrup, C. D., Young, C., Lavallee, R., Nielsen, Michael Lund & Olsen, Jesper Velgaard, 2012, In: Journal of Proteome Research. p. 3487-3497 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination
Falcão, A. M., Meijer, M., Scaglione, A., Rinwa, P., Agirre, E., Liang, J., Buch-Larsen, Sara Charlotte, Heskol, A., Frawley, R., Klingener, M., Varas-Godoy, M., Raposo, A. A. S. F., Ernfors, P., Castro, D. S., Nielsen, Michael Lund, Casaccia, P. & Castelo-Branco, G., 2019, In: Cell Reports. 27, 4, p. 1090-1102.e10Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
Đukić, N., Strømland, Ø., Elsborg, J. D., Munnur, D., Zhu, K., Schuller, M., Chatrin, C., Kar, P., Duma, L., Suyari, O., Rack, J. G. M., Baretić, D., Crudgington, D. R. K., Groslambert, J., Fowler, G., Wijngaarden, S., Prokhorova, E., Rehwinkel, J., Schüler, H., Filippov, D. V. & 5 others, , 2023, In: Science Advances. 9, 37, 19 p., eadi2687.Research output: Contribution to journal › Journal article › Research › peer-review
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Pdx1 is post-translationally modified in vivo and serine 61 is the principal site of phosphorylation
Frogne, T., Sylvestersen, K. B., Kubicek, S., Nielsen, Michael Lund & Hecksher-Sørensen, J., 2012, In: P L o S One. 7, 4, p. e35233Research output: Contribution to journal › Journal article › Research › peer-review
Peptide end sequencing by orthogonal MALDI tandem mass spectrometry
Nielsen, Michael Lund, Bennett, K. L., Larsen, B., Moniatte, M. & Mann, M., 2002, In: Journal of Proteome Research. 1, 1, p. 63-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
PhosTShunter: A fast and reliable tool to detect phosphorylated peptides in liquid chromatography Fourier transform tandem mass spectrometry data sets
Kocher, T., Savitski, M. M., Nielsen, Michael Lund & Zubarev, R. A., 2006, In: Journal of Proteome Research. 5, 3, p. 659-668 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13143239
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Biotin starvation causes mitochondrial protein hyperacetylation and partial rescue by the SIRT3-like deacetylase Hst4p
Research output: Contribution to journal › Journal article › Research › peer-review
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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes
Research output: Contribution to journal › Journal article › Research › peer-review
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Integrative Characterization of the R6/2 Mouse Model of Huntington's Disease Reveals Dysfunctional Astrocyte Metabolism
Research output: Contribution to journal › Journal article › Research › peer-review
Published